Genome Reference Consortium
The Genome Reference Consortium (GRC) is an international collective of academic and research institutes with expertise in genome mapping, sequencing, and informatics, formed to improve the representation of reference genomes. At the time the human reference was initially described, it was clear that some regions were recalcitrant to analysis with existing technology, leaving gaps in the known sequence. The main reason for improving the reference assemblies are that they are the cornerstones upon which all whole genome studies are based (e.g. the 1000 Genomes Project). The GRC is a collaborative effort which interacts with various groups in the scientific community. The primary member institutes are: * The Wellcome Sanger Institute * The McDonnell Genome Institute at Washington University * The European Bioinformatics Institute * The National Center for Biotechnology Information * Zebrafish Model Organism Database * Rat Genome Database The goal of the Consortium is to correct ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Human Whole Genome
Humans (''Homo sapiens'') or modern humans are the most common and widespread species of primate, and the last surviving species of the genus ''Homo''. They are Hominidae, great apes characterized by their Prehistory of nakedness and clothing#Evolution of hairlessness, hairlessness, bipedality, bipedalism, and high Human intelligence, intelligence. Humans have large Human brain, brains, enabling more advanced cognitive skills that facilitate successful adaptation to varied environments, development of sophisticated tools, and formation of complex social structures and civilizations. Humans are Sociality, highly social, with individual humans tending to belong to a Level of analysis, multi-layered network of distinct social groups — from families and peer groups to corporations and State (polity), political states. As such, social interactions between humans have established a wide variety of Value theory, values, norm (sociology), social norms, languages, and traditions (co ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ensembl
Ensembl genome database project is a scientific project at the European Bioinformatics Institute, which provides a centralized resource for geneticists, molecular biologists and other researchers studying the genomes of our own species and other vertebrates and model organisms. Ensembl is one of several well known genome browsers for the retrieval of genomic information. Similar databases and browsers are found at National Center for Biotechnology Information, NCBI and UCSC Genome Browser, the University of California, Santa Cruz (UCSC). History The human genome consists of three billion base pairs, which code for approximately 20,000–25,000 genes. However the genome alone is of little use, unless the locations and relationships of individual genes can be identified. One option is manual annotation, whereby a team of scientists tries to locate genes using experimental data from scientific journals and public databases. However this is a slow, painstaking task. The alternative, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Science And Technology In Cambridgeshire
Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which study the physical world, and the social sciences, which study individuals and societies. While referred to as the formal sciences, the study of logic, mathematics, and theoretical computer science are typically regarded as separate because they rely on deductive reasoning instead of the scientific method as their main methodology. Meanwhile, applied sciences are disciplines that use scientific knowledge for practical purposes, such as engineering and medicine. The history of science spans the majority of the historical record, with the earliest identifiable predecessors to modern science dating to the Bronze Age in Egypt and Mesopotamia (). Their contributions to mathematics, astronomy, and medicine entered and shaped the Greek natural philo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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International Scientific Organizations
International is an adjective (also used as a noun) meaning "between nations". International may also refer to: Music Albums * ''International'' (Kevin Michael album), 2011 * ''International'' (New Order album), 2002 * ''International'' (The Three Degrees album), 1975 *''International'', 2018 album by L'Algérino Songs * The Internationale, the left-wing anthem * "International" (Chase & Status song), 2014 * "International", by Adventures in Stereo from ''Monomania'', 2000 * "International", by Brass Construction from ''Renegades'', 1984 * "International", by Thomas Leer from ''The Scale of Ten'', 1985 * "International", by Kevin Michael from ''International'' (Kevin Michael album), 2011 * "International", by McGuinness Flint from ''McGuinness Flint'', 1970 * "International", by Orchestral Manoeuvres in the Dark from '' Dazzle Ships'', 1983 * "International (Serious)", by Estelle from '' All of Me'', 2012 Politics * Internationalism (politics) * Political international, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genome Projects
Genome projects are scientific endeavours that ultimately aim to determine the complete genome sequence of an organism (be it an animal, a plant, a fungus, a bacterium, an archaean, a protist or a virus) and to annotate protein-coding genes and other important genome-encoded features. The genome sequence of an organism includes the collective DNA sequences of each chromosome in the organism. For a bacterium containing a single chromosome, a genome project will aim to map the sequence of that chromosome. For the human species, whose genome includes 22 pairs of autosomes and 2 sex chromosomes, a complete genome sequence will involve 46 separate chromosome sequences. The Human Genome Project is a well known example of a genome project. Genome assembly Genome assembly refers to the process of taking a large number of short DNA sequences and reassembling them to create a representation of the original chromosomes from which the DNA originated. In a shotgun sequencing project, all th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genomics England
Genomics England is a company wholly owned by the United Kingdom's Department of Health and Social Care. Established in 2013, it was tasked with delivering the 100,000 Genomes Project, a pioneering initiative that sequenced 100,000 genomes from approximately 85,000 National Health Service patients affected by rare conditions and cancers. This project paved the way for the NHS to incorporate genomic medicine into routine care through the NHS Genomic Medicine Service. In March 2024, Dr. Rich Scott was appointed Chief Executive Officer of Genomics England, having first joined the organisation in 2015. History Genomics England was established in July 2013 as a company fully owned by the UK Department of Health and Social Care. The company was launched by Jeremy Hunt, Secretary of State for Health, on 5 July, in an announcement timed to coincide with the 65th birthday of the NHS. Genomics England's first major initiative, the 100,000 Genomes Project, began recruiting patients ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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King's College London
King's College London (informally King's or KCL) is a public university, public research university in London, England. King's was established by royal charter in 1829 under the patronage of George IV of the United Kingdom, King George IV and the Arthur Wellesley, 1st Duke of Wellington, Duke of Wellington. In 1836, King's became one of the two founding colleges of the University of London. It is one of the Third-oldest university in England debate, oldest university-level institutions in England. In the late 20th century, King's grew through a series of mergers, including with Queen Elizabeth College and Chelsea College of Science and Technology (1985), the Institute of Psychiatry (1997), the United Medical and Dental Schools of Guy's and St Thomas' Hospitals and the Florence Nightingale School of Nursing and Midwifery (in 1998). King's operates across five main campuses: the historic Strand Campus in central London, three other Thames-side campuses (Guy's, St Thomas' an ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tim Hubbard
Timothy John Phillip Hubbard is a Professor of Bioinformatics at King's College London, Head of Genome Analysis at Genomics England and Honorary Faculty at the Wellcome Trust Sanger Institute in Cambridge, UK. From 1 March 2024, Hubbard became the director of Europe's Life Science Data Infrastructure ELIXIR. Education Hubbard was educated at the University of Cambridge where he was awarded a Bachelor of Arts degree in Natural Sciences (Biochemistry) in 1985. He went on to do research in protein design in the Department of Crystallography, Birkbeck College, London where he was awarded a PhD in 1988 for research supervised by Tom Blundell. Research and career Hubbard's research interests are in Bioinformatics, Computational biology and Genome Informatics. During his tenure at WTSI he supervised several successful PhD students to completion in these areas of research. Hubbard was appointed Professor of Bioinformatics at King's in October 2013. His research has been published in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Cambridge
The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, world's third-oldest university in continuous operation. The university's founding followed the arrival of scholars who left the University of Oxford for Cambridge after a dispute with local townspeople. The two ancient university, ancient English universities, although sometimes described as rivals, share many common features and are often jointly referred to as Oxbridge. In 1231, 22 years after its founding, the university was recognised with a royal charter, granted by Henry III of England, King Henry III. The University of Cambridge includes colleges of the University of Cambridge, 31 semi-autonomous constituent colleges and List of institutions of the University of Cambridge#Schools, Faculties, and Departments, over 150 academic departm ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Richard M
Richard is a male given name. It originates, via Old French, from Frankish language, Old Frankish and is a Compound (linguistics), compound of the words descending from Proto-Germanic language, Proto-Germanic ''*rīk-'' 'ruler, leader, king' and ''*hardu-'' 'strong, brave, hardy', and it therefore means 'strong in rule'. Nicknames include "Richie", "Dick (nickname), Dick", "Dickon", "Dickie (name), Dickie", "Rich (given name), Rich", "Rick (given name), Rick", "Rico (name), Rico", "Ricky (given name), Ricky", and more. Richard is a common English (the name was introduced into England by the Normans), German and French male name. It's also used in many more languages, particularly Germanic, such as Norwegian, Danish, Swedish, Icelandic, and Dutch, as well as other languages including Irish, Scottish, Welsh and Finnish. Richard is cognate with variants of the name in other European languages, such as the Swedish "Rickard", the Portuguese and Spanish "Ricardo" and the Italian "Ricc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Deanna M
Deanna or DeAnna is a feminine given name. It is a variant of the name Diana apparently created in 1936 as a stage name for actress and singer Deanna Durbin, whose given name was originally Edna Mae. The name is also used as a feminine version of the name Dean. Deanne is a variant. Usage The name was among the top 1,000 names in use for newborn American girls between 1936 and 2013. Its greatest use was between 1938 and 1941, when it was among the top 150 names for girls, and between 1969 and 1971, when it was among the top 100 names for newborn American girls. It was a top 100 name for girls in Canada between 1937 and 1941 and again between 1969 and 1973. It was also among the top 1,000 names for girls in the United Kingdom at different points until 2008. People with the given name * Deanna Archuleta, American politician * Deanna Ballard (born 1978), American politician * Deanna Barch, American psychologist and professor * DeAnna Bennett (born 1984), American mixed martial art ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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UCSC Genome Browser
The UCSC Genome Browser is an online and downloadable genome browser hosted by the University of California, Santa Cruz (UCSC). It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with a large collection of aligned annotations. The Browser is a graphical viewer optimized to support fast interactive performance and is an open-source, web-based tool suite built on top of a MySQL database for rapid visualization, examination, and querying of the data at many levels. The Genome Browser Database, browsing tools, downloadable data files, and documentation can all be found on the UCSC Genome Bioinformatics website. History Origins and Early Development (2000–2003) The UCSC Genome Browser was developed in 2000 by graduate student Jim Kent and Professor David Haussler at the University of California, Santa Cruz (UCSC), to provide public access to the draft human genome sequence ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |