Generalized Estimating Equations
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Generalized Estimating Equations
In statistics, a generalized estimating equation (GEE) is used to estimate the parameters of a generalized linear model with a possible unmeasured correlation between observations from different timepoints. Although some believe that Generalized estimating equations are robust in everything even with the wrong choice of working-correlation matrix, Generalized estimating equations are only robust to loss of consistency with the wrong choice. Regression beta coefficient estimates from the Liang Zeger GEE are consistent, unbiased, asymptotically normal even when the working correlation is misspecified, under mild regularity conditions. GEE is higher in efficiency than generalized linear iterative model GLIM (software) in the presence of high autocorrelation. When the true working-correlation is known, consistency does not require MCAR. Huber-White standard errors improve the efficiency of Liang Zeger GEE in the absence of serial Autocorrelation but may remove the marginal interpretat ...
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Statistics
Statistics (from German language, German: ''wikt:Statistik#German, Statistik'', "description of a State (polity), state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of statistical survey, surveys and experimental design, experiments.Dodge, Y. (2006) ''The Oxford Dictionary of Statistical Terms'', Oxford University Press. When census data cannot be collected, statisticians collect data by developing specific experiment designs and survey sample (statistics), samples. Representative sampling as ...
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Score Test
In statistics, the score test assesses constraints on statistical parameters based on the gradient of the likelihood function—known as the ''score''—evaluated at the hypothesized parameter value under the null hypothesis. Intuitively, if the restricted estimator is near the maximum of the likelihood function, the score should not differ from zero by more than sampling error. While the finite sample distributions of score tests are generally unknown, they have an asymptotic χ2-distribution under the null hypothesis as first proved by C. R. Rao in 1948, a fact that can be used to determine statistical significance. Since function maximization subject to equality constraints is most conveniently done using a Lagrangean expression of the problem, the score test can be equivalently understood as a test of the magnitude of the Lagrange multipliers associated with the constraints where, again, if the constraints are non-binding at the maximum likelihood, the vector of Lagrange mu ...
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Python (programming Language)
Python is a high-level, general-purpose programming language. Its design philosophy emphasizes code readability with the use of significant indentation. Python is dynamically-typed and garbage-collected. It supports multiple programming paradigms, including structured (particularly procedural), object-oriented and functional programming. It is often described as a "batteries included" language due to its comprehensive standard library. Guido van Rossum began working on Python in the late 1980s as a successor to the ABC programming language and first released it in 1991 as Python 0.9.0. Python 2.0 was released in 2000 and introduced new features such as list comprehensions, cycle-detecting garbage collection, reference counting, and Unicode support. Python 3.0, released in 2008, was a major revision that is not completely backward-compatible with earlier versions. Python 2 was discontinued with version 2.7.18 in 2020. Python consistently ranks as ...
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Julia (programming Language)
Julia is a high-level, dynamic programming language. Its features are well suited for numerical analysis and computational science. Distinctive aspects of Julia's design include a type system with parametric polymorphism in a dynamic programming language; with multiple dispatch as its core programming paradigm. Julia supports concurrent, (composable) parallel and distributed computing (with or without using MPI or the built-in corresponding to "OpenMP-style" threads), and direct calling of C and Fortran libraries without glue code. Julia uses a just-in-time (JIT) compiler that is referred to as "just- ahead-of-time" (JAOT) in the Julia community, as Julia compiles all code (by default) to machine code before running it. Julia is garbage-collected, uses eager evaluation, and includes efficient libraries for floating-point calculations, linear algebra, random number generation, and regular expression matching. Many libraries are available, including some (e.g., for fast Fo ...
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R (programming Language)
R is a programming language for statistical computing and graphics supported by the R Core Team and the R Foundation for Statistical Computing. Created by statisticians Ross Ihaka and Robert Gentleman, R is used among data miners, bioinformaticians and statisticians for data analysis and developing statistical software. Users have created packages to augment the functions of the R language. According to user surveys and studies of scholarly literature databases, R is one of the most commonly used programming languages used in data mining. R ranks 12th in the TIOBE index, a measure of programming language popularity, in which the language peaked in 8th place in August 2020. The official R software environment is an open-source free software environment within the GNU package, available under the GNU General Public License. It is written primarily in C, Fortran, and R itself (partially self-hosting). Precompiled executables are provided for various operating systems. R ...
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Stata
Stata (, , alternatively , occasionally stylized as STATA) is a general-purpose statistical software package developed by StataCorp for data manipulation, visualization, statistics, and automated reporting. It is used by researchers in many fields, including biomedicine, epidemiology, sociology and science. Stata was initially developed by Computing Resource Center in California and the first version was released in 1985. In 1993, the company moved to College Station, TX and was renamed Stata Corporation, now known as StataCorp. A major release in 2003 included a new graphics system and dialog boxes for all commands. Since then, a new version has been released once every two years. The current version is Stata 17, released in April 2021. Technical overview and terminology User interface From its creation, Stata has always employed an integrated command-line interface. Starting with version 8.0, Stata has included a graphical user interface based on Qt framework which uses m ...
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SPSS
SPSS Statistics is a statistical software suite developed by IBM for data management, advanced analytics, multivariate analysis, business intelligence, and criminal investigation. Long produced by SPSS Inc., it was acquired by IBM in 2009. Current versions (post 2015) have the brand name: IBM SPSS Statistics. The software name originally stood for Statistical Package for the Social Sciences (SPSS), reflecting the original market, then later changed to Statistical Product and Service Solutions. Overview SPSS is a widely used program for statistical analysis in social science. It is also used by market researchers, health researchers, survey companies, government, education researchers, marketing organizations, data miners, and others. The original SPSS manual (Nie, Bent & Hull, 1970) has been described as one of "sociology's most influential books" for allowing ordinary researchers to do their own statistical analysis. In addition to statistical analysis, data management (ca ...
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SAS (software)
SAS (previously "Statistical Analysis System") is a statistical software suite developed by SAS Institute for data management, advanced analytics, multivariate analysis, business intelligence, criminal investigation, and predictive analytics. SAS was developed at North Carolina State University from 1966 until 1976, when SAS Institute was incorporated. SAS was further developed in the 1980s and 1990s with the addition of new statistical procedures, additional components and the introduction of JMP. A point-and-click interface was added in version 9 in 2004. A social media analytics product was added in 2010. Technical overview and terminology SAS is a software suite that can mine, alter, manage and retrieve data from a variety of sources and perform statistical analysis on it. SAS provides a graphical point-and-click user interface for non-technical users and more through the SAS language. SAS programs have DATA steps, which retrieve and manipulate data, and PROC steps, whic ...
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MATLAB
MATLAB (an abbreviation of "MATrix LABoratory") is a proprietary multi-paradigm programming language and numeric computing environment developed by MathWorks. MATLAB allows matrix manipulations, plotting of functions and data, implementation of algorithms, creation of user interfaces, and interfacing with programs written in other languages. Although MATLAB is intended primarily for numeric computing, an optional toolbox uses the MuPAD symbolic engine allowing access to symbolic computing abilities. An additional package, Simulink, adds graphical multi-domain simulation and model-based design for dynamic and embedded systems. As of 2020, MATLAB has more than 4 million users worldwide. They come from various backgrounds of engineering, science, and economics. History Origins MATLAB was invented by mathematician and computer programmer Cleve Moler. The idea for MATLAB was based on his 1960s PhD thesis. Moler became a math professor at the University of New Mexico and starte ...
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Biometrics (journal)
''Biometrics'' is a journal that publishes articles on the application of statistics and mathematics to the biological sciences. It is published by the International Biometric Society (IBS).Biometrics homepage
Originally published in 1945 under the title ''Biometrics Bulletin'', the journal adopted the shorter title in 1947. Biometrics, Vol. 3, No. 1, Mar., 1947 Page 53
/ref> A notable contributor to the journal was , for whom a memorial edition was published in 1964.
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Quasi-likelihood Under The Independence Model Criterion
In statistics, quasi-likelihood methods are used to estimate parameters in a statistical model when exact likelihood methods, for example maximum likelihood estimation, are computationally infeasible. Due to the wrong likelihood being used, quasi-likelihood estimators lose asymptotic efficiency compared to, e.g., maximum likelihood estimators. Under broadly applicable conditions, quasi-likelihood estimators are consistent and asymptotically normal. The asymptotic covariance matrix can be obtained using the so-called sandwich estimator. Examples of quasi-likelihood methods are the generalized estimating equations and pairwise likelihood approaches. History The term quasi-likelihood function was introduced by Robert Wedderburn in 1974 to describe a function that has similar properties to the log-likelihood function but is not the log-likelihood corresponding to any actual probability distribution. He proposed to fit certain quasi-likelihood models using a straightforward exte ...
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