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Gary Ruvkun
Gary Bruce Ruvkun (born March 1952, Berkeley, California) is an American molecular biologist at Massachusetts General Hospital and professor of genetics at Harvard Medical School in Boston. Ruvkun discovered the mechanism by which ''lin-4'', the first microRNA (miRNA) discovered by Victor Ambros, regulates the translation of target messenger RNAs via imperfect base-pairing to those targets, and discovered the second miRNA, ''let-7'', and that it is conserved across animal phylogeny, including in humans. These miRNA discoveries revealed a new world of RNA regulation at an unprecedented small size scale, and the mechanism of that regulation. Ruvkun also discovered many features of insulin-like signaling in the regulation of aging and metabolism. He was elected a Member of the American Philosophical Society in 2019. Education Ruvkun obtained his undergraduate degree in 1973 at the University of California, Berkeley. His PhD work was done at Harvard University in the laboratory of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Berkeley, California
Berkeley ( ) is a city on the eastern shore of San Francisco Bay in northern Alameda County, California, United States. It is named after the 18th-century Irish bishop and philosopher George Berkeley. It borders the cities of Oakland and Emeryville to the south and the city of Albany and the unincorporated community of Kensington to the north. Its eastern border with Contra Costa County generally follows the ridge of the Berkeley Hills. The 2020 census recorded a population of 124,321. Berkeley is home to the oldest campus in the University of California System, the University of California, Berkeley, and the Lawrence Berkeley National Laboratory, which is managed and operated by the university. It also has the Graduate Theological Union, one of the largest religious studies institutions in the world. Berkeley is considered one of the most socially progressive cities in the United States. History Indigenous history The site of today's City of Berkeley was the territo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Walter Gilbert
Walter Gilbert (born March 21, 1932) is an American biochemist, physicist, molecular biology pioneer, and Nobel laureate. Education and early life Walter Gilbert was born in Boston, Massachusetts, on March 21, 1932, the son of Emma (Cohen), a child psychologist, and Richard V. Gilbert, an economist. When Gilbert was seven years old, the family moved to the Washington D.C. area so his father could work under Harry Hopkins on the New Deal brain trust. While living in Washington the family became friends with the family of I.F. Stone and Wally met Stone's oldest daughter, Celia, when they were both 8. They later married at age 21. He was educated at the Sidwell Friends School, and attended Harvard University for undergraduate and graduate studies, earning a baccalaureate in chemistry and physics in 1953 and a master's degree in physics in 1954. He studied for his doctorate at the University of Cambridge, where he earned a PhD in physics supervised by the Nobel laureate Abdus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New Yorker
''The New Yorker'' is an American weekly magazine featuring journalism, commentary, criticism, essays, fiction, satire, cartoons, and poetry. Founded as a weekly in 1925, the magazine is published 47 times annually, with five of these issues covering two-week spans. Although its reviews and events listings often focus on the Culture of New York City, cultural life of New York City, ''The New Yorker'' has a wide audience outside New York and is read internationally. It is well known for its illustrated and often topical covers, its commentaries on popular culture and eccentric American culture, its attention to modern fiction by the inclusion of Short story, short stories and literary reviews, its rigorous Fact-checking, fact checking and copy editing, its journalism on politics and social issues, and its single-panel cartoons sprinkled throughout each issue. Overview and history ''The New Yorker'' was founded by Harold Ross and his wife Jane Grant, a ''The New York Times, N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Panspermia
Panspermia () is the hypothesis, first proposed in the 5th century BCE by the Greek philosopher Anaxagoras, that life exists throughout the Universe, distributed by space dust, meteoroids, asteroids, comets, and planetoids, as well as by spacecraft carrying unintended contamination by microorganisms.Forward planetary contamination like '' Tersicoccus phoenicis'', that has shown resistance to methods usually used in spacecraft assembly clean rooms: Panspermia is a fringe theory with little support amongst mainstream scientists. Critics argue that it does not answer the question of the origin of life but merely places it on another celestial body. It is also criticized because it cannot be tested experimentally. Panspermia proposes (for example) that microscopic lifeforms which can survive the effects of space (such as extremophiles) can become trapped in debris ejected into space after collisions between planets and small Solar System bodies that harbor life. Panspermia studies c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Earliest Known Life Forms
The earliest known life forms on Earth are believed to be fossilized microorganisms found in hydrothermal vent precipitates, considered to be about 3.42 billion years old. The earliest time for the Abiogenesis, origin of life on Earth is at least 3.77 billion years ago, possibly as early as 4.28 billion years ago—not long after the oceans Origin of water on Earth#History of water on Earth, formed 4.5 billion years ago, and after the Age of Earth, formation of the Earth 4.54 billion years ago. The earliest ''direct'' evidence of life on Earth is from Micropaleontology#Microfossils, microfossils of microorganisms permineralized in 3.465-billion-year-old Australian Apex chert rocks. Biosphere Earth remains the only place in the universe known to harbor life. The Abiogenesis, origin of life on Earth was at least 3.77 billion years ago, possibly as early as 4.28 billion years ago. The Earth's biosphere extends down to at least below the surface, and up to at least into the A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Life
Life is a quality that distinguishes matter that has biological processes, such as signaling and self-sustaining processes, from that which does not, and is defined by the capacity for growth, reaction to stimuli, metabolism, energy transformation, and reproduction. Various forms of life exist, such as plants, animals, fungi, protists, archaea, and bacteria. Biology is the science that studies life. The gene is the unit of heredity, whereas the Cell (biology), cell is the structural and functional unit of life. There are two kinds of cells, prokaryotic and eukaryotic, both of which consist of cytoplasm enclosed within a membrane and contain many biomolecules such as proteins and nucleic acids. Cells reproduce through a process of cell division, in which the parent cell divides into two or more daughter cells and passes its genes onto a new generation, sometimes producing genetic variation. Organisms, or the individual entities of life, are generally thought t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Abiogenesis
In biology, abiogenesis (from a- 'not' + Greek bios 'life' + genesis 'origin') or the origin of life is the natural process by which life has arisen from non-living matter, such as simple organic compounds. The prevailing scientific hypothesis is that the transition from non-living to living entities on Earth was not a single event, but an evolutionary process of increasing complexity that involved the formation of a habitable planet, the prebiotic synthesis of organic molecules, molecular self-replication, self-assembly, autocatalysis, and the emergence of cell membranes. Many proposals have been made for different stages of the process. The study of abiogenesis aims to determine how pre-life chemical reactions gave rise to life under conditions strikingly different from those on Earth today. It primarily uses tools from biology and chemistry, with more recent approaches attempting a synthesis of many sciences. Life functions through the specialized chemistry of carbon and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Life On Mars
The possibility of life on Mars is a subject of interest in astrobiology due to the planet's proximity and similarities to Earth. To date, no proof of past or present life has been found on Mars. Cumulative evidence suggests that during the ancient Noachian time period, the surface environment of Mars had liquid water and may have been habitable for microorganisms, but habitable conditions do not necessarily indicate life. Scientific searches for evidence of life began in the 19th century and continue today via telescopic investigations and deployed probes. While early work focused on phenomenology and bordered on fantasy, the modern scientific inquiry has emphasized the search for water, chemical biosignatures in the soil and rocks at the planet's surface, and biomarker gases in the atmosphere. Mars is of particular interest for the study of the origins of life because of its similarity to the early Earth. This is especially true since Mars has a cold climate and lacks pl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mars
Mars is the fourth planet from the Sun and the second-smallest planet in the Solar System, only being larger than Mercury (planet), Mercury. In the English language, Mars is named for the Mars (mythology), Roman god of war. Mars is a terrestrial planet with a thin atmosphere (less than 1% that of Earth's), and has a crust primarily composed of elements similar to Earth's crust, as well as a core made of iron and nickel. Mars has surface features such as impact craters, valleys, dunes and polar ice caps. It has two small and irregularly shaped moons, Phobos (moon), Phobos and Deimos (moon), Deimos. Some of the most notable surface features on Mars include Olympus Mons, the largest volcano and List of tallest mountains in the Solar System, highest known mountain in the Solar System and Valles Marineris, one of the largest canyons in the Solar System. The North Polar Basin (Mars), Borealis basin in the Northern Hemisphere covers approximately 40% of the planet and may be a la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DNA Sequencer
A DNA sequencer is a scientific instrument used to automate the DNA sequencing process. Given a sample of DNA, a DNA sequencer is used to determine the order of the four bases: G (guanine), C (cytosine), A (adenine) and T (thymine). This is then reported as a text string, called a read. Some DNA sequencers can be also considered optical instruments as they analyze light signals originating from fluorochromes attached to nucleotides. The first automated DNA sequencer, invented by Lloyd M. Smith, was introduced by Applied Biosystems in 1987. It used the Sanger sequencing method, a technology which formed the basis of the "first generation" of DNA sequencers and enabled the completion of the human genome project in 2001. This first generation of DNA sequencers are essentially automated electrophoresis systems that detect the migration of labelled DNA fragments. Therefore, these sequencers can also be used in the genotyping of genetic markers where only the length of a DNA fragmen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NASA
The National Aeronautics and Space Administration (NASA ) is an independent agency of the US federal government responsible for the civil space program, aeronautics research, and space research. NASA was established in 1958, succeeding the National Advisory Committee for Aeronautics (NACA), to give the U.S. space development effort a distinctly civilian orientation, emphasizing peaceful applications in space science. NASA has since led most American space exploration, including Project Mercury, Project Gemini, the 1968-1972 Apollo Moon landing missions, the Skylab space station, and the Space Shuttle. NASA supports the International Space Station and oversees the development of the Orion spacecraft and the Space Launch System for the crewed lunar Artemis program, Commercial Crew spacecraft, and the planned Lunar Gateway space station. The agency is also responsible for the Launch Services Program, which provides oversight of launch operations and countdown management f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Berkeley
The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant university and the founding campus of the University of California system. Its fourteen colleges and schools offer over 350 degree programs and enroll some 31,800 undergraduate and 13,200 graduate students. Berkeley ranks among the world's top universities. A founding member of the Association of American Universities, Berkeley hosts many leading research institutes dedicated to science, engineering, and mathematics. The university founded and maintains close relationships with three national laboratories at Berkeley, Livermore and Los Alamos, and has played a prominent role in many scientific advances, from the Manhattan Project and the discovery of 16 chemical elements to breakthroughs in computer science and genomics. Berkeley is also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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