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GENESIS (software)
GENESIS (The ''General Neural Simulation System'') is a simulation environment for constructing realistic models of neurobiological systems at many levels of scale including: sub-cellular processes, individual neurons, networks of neurons, and neuronal systems. These simulations are “computer-based implementations of models whose primary objective is to capture what is known of the anatomical structure and physiological characteristics of the neural system of interest”. GENESIS is intended to quantify the physical framework of the nervous system in a way that allows for easy understanding of the physical structure of the nerves in question. “At present only GENESIS allows parallelized modeling of single neurons and networks on multiple-instruction-multiple-data parallel computers.” Development of GENESIS software spread from its home at Caltech to labs at the University of Texas at San Antonio, the University of Antwerp, the National Centre for Biological Sciences in Banga ...
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James M
James is a common English language surname and given name: *James (name), the typically masculine first name James * James (surname), various people with the last name James James or James City may also refer to: People * King James (other), various kings named James * Saint James (other) * James (musician) * James, brother of Jesus Places Canada * James Bay, a large body of water * James, Ontario United Kingdom * James College, a college of the University of York United States * James, Georgia, an unincorporated community * James, Iowa, an unincorporated community * James City, North Carolina * James City County, Virginia ** James City (Virginia Company) ** James City Shire * James City, Pennsylvania * St. James City, Florida Arts, entertainment, and media * ''James'' (2005 film), a Bollywood film * ''James'' (2008 film), an Irish short film * ''James'' (2022 film), an Indian Kannada-language film * James the Red Engine, a character in ''Thomas the Tank En ...
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Dendrite
Dendrites (from Greek δένδρον ''déndron'', "tree"), also dendrons, are branched protoplasmic extensions of a nerve cell that propagate the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project. Electrical stimulation is transmitted onto dendrites by upstream neurons (usually via their axons) via synapses which are located at various points throughout the dendritic tree. Dendrites play a critical role in integrating these synaptic inputs and in determining the extent to which action potentials are produced by the neuron. Dendritic arborization, also known as dendritic branching, is a multi-step biological process by which neurons form new dendritic trees and branches to create new synapses. The morphology of dendrites such as branch density and grouping patterns are highly correlated to the function of the neuron. Malformation of dendrites is also tightly correlated to impaired nervous syste ...
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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the brain ...
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How Genesis Works Screen Shot
How may refer to: * How (greeting), a word used in some misrepresentations of Native American/First Nations speech * How, an interrogative word in English grammar Art and entertainment Literature * ''How'' (book), a 2007 book by Dov Seidman * ''HOW'' (magazine), a magazine for graphic designers * H.O.W. Journal, an American art and literary journal Music * "How", a song by The Cranberries from ''Everybody Else Is Doing It, So Why Can't We?'' * "How", a song by Maroon 5 from ''Hands All Over'' * "How", a song by Regina Spektor from ''What We Saw from the Cheap Seats'' * "How", a song by Daughter from ''Not to Disappear'' * "How?" (song), by John Lennon Other media * HOW (graffiti artist), Raoul Perre, New York graffiti muralist * ''How'' (TV series), a British children's television show * ''How'' (video game), a platform game People * How (surname) * HOW (graffiti artist), Raoul Perre, New York graffiti muralist Places * How, Cumbria, England * How, Wisco ...
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GENESIS Screenshot
Genesis may refer to: Bible * Book of Genesis, the first book of the biblical scriptures of both Judaism and Christianity, describing the creation of the Earth and of mankind * Genesis creation narrative, the first several chapters of the Book of Genesis, which describes the origin of the Earth * Genesis Rabbah, a midrash probably written between 300 and 500 CE with some later additions, comprising a collection of interpretations of the Book of Genesis Literature and comics * Genesis (DC Comics), a 1997 DC Comics crossover * Genesis (Marvel Comics), a Marvel Comics supervillain * Genesis, a fictional character in the comic book series ''Preacher'' * ''Genesis'', a 1951 story by H. Beam Piper * ''Genesis: The Origins of Man and the Universe'', a 1982 science text by John Gribbin * ''Genesis'', a 1988 epic poem by Frederick Turner * ''Genesis'', a 2000 story by Poul Anderson * ''Genesis'' (novel), a 2006 work by Bernard Beckett * ''Genesis'', a 2007 story by Paul Chafe * ''Gene ...
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Theoretical Neuromorphology
Theoretical neuromorphology is the science of using morphology to mathematically describe the shape and the connectivity in the nervous system. History The rational study of shapes has been long to form. In the major progresses made during the last century, it is important to differentiate morphogenesis (the way forms are made) and morphology (realized forms). Morphogenesis Important conceptual changes about forms came from d'Arcy Thompson’s essay (1917) dealing with forms in nature. These were not considered as static but as the result of morphogenetic factors. Not knowable in its intimate nature, form is defined as the simple result of forces. Thom (1974), founder of the "catastrophe theory" acknowledged what he owed to this work. A series of various branches of non-linear mathematics catastrophe theory, the fractal theory, the theory of "dissipative structures", the chaos theory have led to what Boutot (1993) called "the morphologic revolution", which has deeply modified th ...
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Neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body (soma), dendrites, and a single axon. The soma is a compact structure, and the axon and dend ...
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Sub-cellular
The cell is the basic structural and functional unit of life forms. Every cell consists of a cytoplasm enclosed within a membrane, and contains many biomolecules such as proteins, DNA and RNA, as well as many small molecules of nutrients and metabolites.Cell Movements and the Shaping of the Vertebrate Body
in Chapter 21 of
Molecular Biology of the Cell
'' fourth edition, edited by Bruce Alberts (2002) published by Garland Science. The Alberts text discusses how the "cellular building blocks" move to shape developing s. It is also common to d ...
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Intel Paragon
The Intel Paragon is a discontinued series of massively parallel supercomputers that was produced by Intel in the 1990s. The Paragon XP/S is a productized version of the experimental ''Touchstone Delta'' system that was built at Caltech, launched in 1992. The Paragon superseded Intel's earlier iPSC/860 system, to which it is closely related. The Paragon series is based on the Intel i860 RISC microprocessor. Up to 2048 (later, up to 4096) i860s are connected in a 2D grid. In 1993, an entry-level Paragon XP/E variant was announced with up to 32 compute nodes. The system architecture is a partitioned system, with the majority of the system comprising diskless compute nodes and a small number of I/O nodes interactive service nodes. Since the bulk of the nodes have no permanent storage, it is possible to "Red/Black switch" the compute partition from classified to unclassified by disconnecting one set of I/O nodes with classified disks and then connecting an unclassified I/O partitio ...
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Open Software
Open-source software (OSS) is computer software that is released under a license in which the copyright holder grants users the rights to use, study, change, and distribute the software and its source code to anyone and for any purpose. Open-source software may be developed in a collaborative public manner. Open-source software is a prominent example of open collaboration, meaning any capable user is able to participate online in development, making the number of possible contributors indefinite. The ability to examine the code facilitates public trust in the software. Open-source software development can bring in diverse perspectives beyond those of a single company. A 2008 report by the Standish Group stated that adoption of open-source software models has resulted in savings of about $60 billion per year for consumers. Open source code can be used for studying and allows capable end users to adapt software to their personal needs in a similar way user scripts an ...
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Marine Biological Laboratory
The Marine Biological Laboratory (MBL) is an international center for research and education in biological and environmental science. Founded in Woods Hole, Massachusetts, in 1888, the MBL is a private, nonprofit institution that was independent for most of its history, but became officially affiliated with the University of Chicago on July 1, 2013. It also collaborates with numerous other institutions. As of 2022, 60 Nobel Prize winners have been affiliated with MBL as students, faculty members or researchers. In addition since 1960, there have been, 137 Howard Hughes Medical Institute investigators, early career scientists, international researchers, and professors; 306 members of the National Academy of Sciences; and 236 Members of the American Academy of Arts and Sciences who have been affiliated with the lab. History 19th century The Marine Biological Laboratory grew from the vision of several Bostonians and Spencer Fullerton Baird, the United States' first Fish Commiss ...
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Caltech
The California Institute of Technology (branded as Caltech or CIT)The university itself only spells its short form as "Caltech"; the institution considers other spellings such a"Cal Tech" and "CalTech" incorrect. The institute is also occasionally referred to as "CIT", most notably in its alma mater, but this is uncommon. is a private university, private research university in Pasadena, California. Caltech is ranked among the best and most selective academic institutions in the world, and with an enrollment of approximately 2400 students (acceptance rate of only 5.7%), it is one of the world's most selective universities. The university is known for its strength in science and engineering, and is among a small group of Institute of Technology (United States), institutes of technology in the United States which is primarily devoted to the instruction of pure and applied sciences. The institution was founded as a preparatory and vocational school by Amos G. Throop in 1891 and began ...
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