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GALVmed
The Global Alliance for Livestock Veterinary Medicines (GALVmed), formerly the Global Alliance for Livestock Vaccines (GALV), is a not-for-profit livestock health product development and access partnership. It operates as a public-private partnership and a UK registered charity headquartered in Edinburgh. GALVmed’s purpose is "protecting livestock, improving human lives" and its mission is to improve the livelihoods of resource-poor farmers by providing animal health tools within a sustainable economic framework. The intended beneficiaries of GALVmed’s work are many of the 900 million people worldwide who rely on livestock for their livelihoods. History Originally GALVmed was known as the Global Alliance for Livestock Vaccines (GALV). GALV was founded in 2004. Earlier, in the early 2000s, scoping work under the DFID Animal Health Programme (AHP), identified the need for an organisation to promote the creation of a consortium to invest in research to produce livestock vacci ...
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Nagana
Animal trypanosomiasis, also known as nagana and nagana pest, or sleeping sickness, is a disease of vertebrates. The disease is caused by trypanosomes of several species in the genus ''Trypanosoma'' such as ''Trypanosoma brucei''. ''Trypanosoma vivax'' causes nagana mainly in West Africa, although it has spread to South America. The trypanosomes infect the blood of the vertebrate host, causing fever, weakness, and lethargy, which lead to weight loss and anemia; in some animals the disease is fatal unless treated. The trypanosomes are transmitted by tsetse flies. An interesting feature is the remarkable tolerance to nagana pathology shown by some breeds of cattle, notably the N'Dama – a West African ''Bos taurus'' breed. This contrasts with the susceptibility shown by East African '' Bos indicus'' cattle such as the zebu. Transmission Most trypanosomes develop in tsetse flies (''Glossina'' spp.), its biological vector, in about one to a few weeks. When an infected tsetse fly b ...
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GAVI Alliance
GAVI, officially Gavi, the Vaccine Alliance (previously the GAVI Alliance, and before that the Global Alliance for Vaccines and Immunization) is a Public–private partnership, public–private global health partnership with the goal of increasing access to immunization in poor countries. In 2016, Gavi channeled more than half of total donor assistance for health, and most donor assistance for immunization, by monetary measure. Gavi supports the immunization of almost half the world's children. Gavi has helped immunize over 760 million children, preventing over 13 million deaths worldwide, helping increase DPT vaccine, diphtheria vaccine coverage in supported countries from 59% in 2000 to 81% in 2019, contributing to reducing child mortality by half. It also seeks to improve the economics of vaccines, negotiating bulk prices, supporting price discrimination, and reducing the commercial risks that manufacturers face when selling vaccines to the poor and developing vaccin ...
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DFID
, type = Department , logo = DfID.svg , logo_width = 180px , logo_caption = , picture = File:Admiralty Screen (411824276).jpg , picture_width = 180px , picture_caption = Department for International Development (London office) (far right) , seal = , seal_width = , seal_caption = , formed = 1997 , preceding1 = Ministry of Overseas Development (ODM) , preceding2 = Overseas Development Administration (ODA) , dissolved = 2 September 2020 , superseding = Foreign, Commonwealth and Development Office , jurisdiction = United Kingdom , headquarters = 22 Whitehall, London, EnglandEast Kilbride, Scotland , employees = , budget = £13.4bn , minister1_name = , minister1_pfo = , minister2_name = , minister2_pfo = , minister3_name = , minister3_pfo = , chief1_name = , chief1_position = , chief2_name = , chief2_position = , child1_agency = , website = , footnotes = , chief3_name = , chief3_position = , chief4_name = , chief4_position = , chief ...
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Bill & Melinda Gates Foundation
The Bill & Melinda Gates Foundation (BMGF), a merging of the William H. Gates Foundation and the Gates Learning Foundation, is an American private foundation founded by Bill Gates and Melinda French Gates. Based in Seattle, Washington, it was launched in 2000 and is reported as of 2020 to be the second largest charitable foundation in the world, holding $49.8 billion in assets. On his 43rd birthday, Bill Gates gave the foundation $1 billion. The primary stated goals of the foundation are to enhance healthcare and reduce extreme poverty across the world, and to expand educational opportunities and access to information technology in the U.S. Key individuals of the foundation include Bill Gates, Melinda French Gates, Warren Buffett, chief executive officer Mark Suzman, and Michael Larson. The BMGF had an endowment of approximately $50 billion . The scale of the foundation and the way it seeks to apply business techniques to giving makes it one of the leaders in venture philanthr ...
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Zoonotic
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. Typically, the first infected human transmits the infectious agent to at least one other human, who, in turn, infects others. Major modern diseases such as Ebola virus disease and salmonellosis are zoonoses. HIV was a zoonotic disease transmitted to humans in the early part of the 20th century, though it has now evolved into a separate human-only disease. Most strains of influenza that infect humans are human diseases, although many strains of bird flu and swine flu are zoonoses; these viruses occasionally recombine with human strains of the flu and can cause pandemics such as the 1918 Spanish flu or the 2009 swine flu. ''Taenia solium'' infection is one of the neglected tropical diseases with public health and veterinary concern in ende ...
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East Coast Fever
East Coast fever, also known as theileriosis, is a disease of cattle which occurs in Africa and is caused by the protozoan parasite ''Theileria parva''. The primary vector which spreads ''T. parva'' between cattle is a tick, ''Rhipicephalus appendiculatus''. East Coast fever is of major economic importance to livestock farmers in Africa, killing at least one million cattle each year. The disease occurs in Burundi, Democratic Republic of Congo, Kenya, Malawi, Mozambique, Rwanda, South Sudan, Tanzania, Uganda, Zimbabwe, Zambia. In 2003, East Coast fever was introduced to Comoros by cattle imported from Tanzania. It has been eradicated in South Africa. A more acute form of East Coast fever called corridor disease occurs when buffalo-derived ''T. parva'' is transmitted to cattle. Another form, called January disease, only occurs over the winter months in Zimbabwe due to the tick lifecycle. Native cattle are often resistant to the parasite, but not without symptoms. They are hosts ...
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Newcastle Disease
Virulent Newcastle disease (VND), formerly exotic Newcastle disease, is a contagious viral avian disease affecting many domestic and wild bird species; it is transmissible to humans. Though it can infect humans, most cases are non-symptomatic; rarely it can cause a mild fever and influenza-like symptoms and/or conjunctivitis in humans. Its effects are most notable in domestic poultry due to their high susceptibility and the potential for severe impacts of an epizootic on the poultry industries. It is endemic to many countries. No treatment for VND is known, but the use of prophylactic vaccines and sanitary measures reduces the likelihood of outbreaks. The disease is caused by Newcastle disease virus (NDV), an avulavirus. Strains of Newcastle disease virus have been used to treat cancer in humans, since the virus appears to preferentially infect and kill cancerous cells. Strains of Newcastle disease virus have also been used to create viral vector vaccine candidates against Ebo ...
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Contagious Caprine Pleuropneumonia
{{Taxobox , name = ''Mycoplasma capricolum'' subsp. ''capricolum'' , regnum = Bacteria , phylum = Mycoplasmatota , classis = Mollicutes , ordo = Mycoplasmatales , familia = Mycoplasmataceae , genus = ''Mycoplasma'' , species = ''M. capricolum'' , subspecies = ''capricolum'' Contagious caprine pleuropneumonia (CCPP) is a cause of major economic losses to goat producers in Africa, Asia and the Middle East. Disease is caused by members of the Mycoplasma genus – usually ''Mycoplasma capricolum'' subsp. ''capricolum'' but sometimes by ''M. mycoides'' subsp. ''capri'' or ''M. mycoides'' subsp. ''mycoides''. It is extremely contagious with very high morbidity and mortality rates, causing an interstitial fibrinous pleuropneumonia in infected goats. Infection is spread by close-contact aerosol, therefore overcrowding and confinement increases disease incidence. Stress factors such as malnutrition and long transport can also predispose animals to disease. Goats are the only ...
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Contagious Bovine Pleuropneumonia
Contagious bovine pleuropneumonia (CBPP – also known as lung plague), is a contagious bacterial disease that afflicts the lungs of cattle, buffalo, zebu, and yaks. It is caused by the bacterium ''Mycoplasma mycoides'', and the symptoms are pneumonia and inflammation of the lung membranes. The incubation period is 20 to 123 days. It was particularly widespread in the United States in 1879, affecting herds from several states. The outbreak was so severe that it resulted in a trade embargo by the British government, blocking U.S. cattle exports to Britain and Canada. This prompted the United States to establish the Bureau of Animal Industry, set up in 1884 to eradicate the disease, which it succeeded in doing by 1892. Louis Willems, a Belgian doctor, began pioneering work in the 1850s on animal inoculation against the disease. The bacteria are widespread in Africa, the Middle East, Southern Europe, as well as parts of Asia. It is an airborne species, and can travel up to several k ...
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Peste Des Petits Ruminants
Ovine rinderpest, also commonly known as ''peste des petits ruminants'' (PPR), is a contagious disease primarily affecting goats and sheep; however, camels and wild small ruminants can also be affected. PPR is currently present in North, Central, West and East Africa, the Middle East, and South Asia. It is caused by ''small ruminants morbillivirus'' in the genus ''Morbillivirus,'' and is closely related to, among others,'' rinderpest morbillivirus, measles morbillivirus'', and ''canine morbillivirus'' (previously known as canine distemper virus). The disease is highly contagious, and can have an 80–100% mortality rate in acute cases in an epizootic setting. The virus does not infect humans. The disease was first described in 1942 in Côte d'Ivoire, and has since been detected in more than 70 countries in the world. In 2017, the disease was reported to be affecting saiga in Mongolia, causing near-catastrophic herd depletion for the endangered species. In 2018, it was stat ...
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African Swine Fever
''African swine fever virus'' (ASFV) is a large, double-stranded DNA virus in the '' Asfarviridae'' family. It is the causative agent of African swine fever (ASF). The virus causes a hemorrhagic fever with high mortality rates in domestic pigs; some isolates can cause death of animals as quickly as a week after infection. It persistently infects its natural hosts, warthogs, bushpigs, and soft ticks of the genus ''Ornithodoros'', which likely act as a vector, with no disease signs. It does not cause disease in humans. ASFV is endemic to sub-Saharan Africa and exists in the wild through a cycle of infection between ticks and wild pigs, bushpigs, and warthogs. The disease was first described after European settlers brought pigs into areas endemic with ASFV, and as such, is an example of an emerging infectious disease. ASFV replicates in the cytoplasm of infected cells. It is the only virus with a double-stranded DNA genome known to be transmitted by arthropods. Virology A ...
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