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Franz Hillenkamp
Franz Hillenkamp (March 18, 1936 – August 22, 2014) was a German scientist known for his development of the laser microprobe mass analyzer and, with Michael Karas, matrix-assisted laser desorption/ionization (MALDI). Early life and education Franz Hillenkamp was born in 1936 in Essen, Germany. He attended high school in Lünen, graduating in 1955. He received a M.S. degree in electrical engineering from Purdue University in 1961. He received a Ph.D. (Dr.-Ing.) from the Technische Universität München in 1966 with a thesis entitled “An Absolutely Calibrated Calorimeter for the Measurement of Pulsed Laser Radiation.” Academic career Hillenkamp was a professor at Goethe University Frankfurt in Frankfurt from 1982 to 1986. In 1986, he became a professor on the Medical Faculty of the University of Münster where he remained until his retirement in 2001. Laser microprobe In 1973, Hillenkamp developed a high performance laser microprobe mass spectrometer with a spatial resolution ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Münster
Münster (; nds, Mönster) is an independent city (''Kreisfreie Stadt'') in North Rhine-Westphalia, Germany. It is in the northern part of the state and is considered to be the cultural centre of the Westphalia region. It is also a state district capital. Münster was the location of the Anabaptist rebellion during the Protestant Reformation and the site of the signing of the Treaty of Westphalia ending the Thirty Years' War in 1648. Today it is known as the bicycle capital of Germany. Münster gained the status of a ''Großstadt'' (major city) with more than 100,000 inhabitants in 1915. , there are 300,000 people living in the city, with about 61,500 students, only some of whom are recorded in the official population statistics as having their primary residence in Münster. Münster is a part of the international Euregio region with more than 1,000,000 inhabitants (Enschede, Hengelo, Gronau, Osnabrück). History Early history In 793, Charlemagne sent out Ludger as a miss ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mass Spectrometry Imaging
Mass spectrometry imaging (MSI) is a technique used in mass spectrometry to visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses. After collecting a mass spectrum at one spot, the sample is moved to reach another region, and so on, until the entire sample is scanned. By choosing a peak in the resulting spectra that corresponds to the compound of interest, the MS data is used to map its distribution across the sample. This results in pictures of the spatially resolved distribution of a compound pixel by pixel. Each data set contains a veritable gallery of pictures because any peak in each spectrum can be spatially mapped. Despite the fact that MSI has been generally considered a qualitative method, the signal generated by this technique is proportional to the relative abundance of the analyte. Therefore, quantification is possible, when its challenges are overcome. Although widely used traditional methodologies ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1936 Births
Events January–February * January 20 – George V of the United Kingdom and the British Dominions and Emperor of India, dies at his Sandringham Estate. The Prince of Wales succeeds to the throne of the United Kingdom as King Edward VIII. * January 28 – Britain's King George V state funeral takes place in London and Windsor. He is buried at St George's Chapel, Windsor Castle * February 4 – Radium E (bismuth-210) becomes the first radioactive element to be made synthetically. * February 6 – The 1936 Winter Olympics, IV Olympic Winter Games open in Garmisch-Partenkirchen, Germany. * February 10–February 19, 19 – Second Italo-Ethiopian War: Battle of Amba Aradam – Italian forces gain a decisive tactical victory, effectively neutralizing the army of the Ethiopian Empire. * February 16 – 1936 Spanish general election: The left-wing Popular Front (Spain), Popular Front coalition takes a majority. * February 26 – February 26 Inci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientists From North Rhine-Westphalia
A scientist is a person who conducts scientific research to advance knowledge in an area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosophical study of nature called natural philosophy, a precursor of natural science. Though Thales (circa 624-545 BC) was arguably the first scientist for describing how cosmic events may be seen as natural, not necessarily caused by gods,Frank N. Magill''The Ancient World: Dictionary of World Biography'', Volume 1 Routledge, 2003 it was not until the 19th century that the term ''scientist'' came into regular use after it was coined by the theologian, philosopher, and historian of science William Whewell in 1833. In modern times, many scientists have advanced degrees in an area of science and pursue careers in various sectors of the economy such as academia, industry, government, and nonprofit environments.'''' History The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mass Spectrometrists
Mass is an intrinsic property of a body. It was traditionally believed to be related to the quantity of matter in a physical body, until the discovery of the atom and particle physics. It was found that different atoms and different elementary particles, theoretically with the same amount of matter, have nonetheless different masses. Mass in modern physics has multiple definitions which are conceptually distinct, but physically equivalent. Mass can be experimentally defined as a measure of the body's inertia, meaning the resistance to acceleration (change of velocity) when a net force is applied. The object's mass also determines the strength of its gravitational attraction to other bodies. The SI base unit of mass is the kilogram (kg). In physics, mass is not the same as weight, even though mass is often determined by measuring the object's weight using a spring scale, rather than balance scale comparing it directly with known masses. An object on the Moon would weigh l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
History Of Mass Spectrometry
The history of mass spectrometry has its roots in physical and chemical studies regarding the nature of matter. The study of gas discharges in the mid 19th century led to the discovery of anode and cathode rays, which turned out to be positive ions and electrons. Improved capabilities in the separation of these positive ions enabled the discovery of stable isotopes of the elements. The first such discovery was with the element neon, which was shown by mass spectrometry to have at least two stable isotopes: 20Ne (neon with 10 protons and 10 neutrons) and 22Ne (neon with 10 protons and 12 neutrons). Mass spectrometers were used in the Manhattan Project for the separation of isotopes of uranium necessary to create the atomic bomb. Prout's Hypothesis Prout's hypothesis was an early 19th-century attempt to explain the properties of the chemical elements using the internal structure of the atom. In 1815, the English chemist William Prout observed that the atomic weights that had been mea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Mass Spectrometry Foundation
The International Mass Spectrometry Foundation (IMSF) is a non-profit scientific organization in the field of mass spectrometry. It operates the International Mass Spectrometry Society, which consists of 37 member societies and sponsors the International Mass Spectrometry Conference that is held once every two years. Aims The foundation has four aims: # organizing international conferences and workshops in mass spectrometry # improving mass spectrometry education # standardizing terminology in the field # aiding in the dissemination of mass spectrometry through publications Conferences Before the formation of the IMSF, the first International Mass Spectrometry Conference was held in London in 1958 and 41 papers were presented. Since then, conferences were held every three years until 2012, and every two years since. Conference proceedings are published in a book series, ''Advances in Mass Spectrometry'', which is the oldest continuous series of publications in mass spectrometry. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society For Mass Spectrometry
The American Society for Mass Spectrometry (ASMS) is a professional association based in the United States that supports the scientific field of mass spectrometry. As of 2018, the society had approximately 10,000 members primarily from the US, but also from around the world. The society holds a large annual meeting, typically in late May or early June as well as other topical conferences and workshops. The society publishes the Journal of the American Society for Mass Spectrometry. Awards The Society recognizes achievements and promotes academic research through four annual awards. The Biemann Medal and the John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry both are awarded in recognition of singular achievements or contributions in fundamental or applied mass spectrometry, with the Biemann Medal being focused on individuals who are early in their careers. The Ronald A. Hites Award is awarded for outstanding original research demonstrated in papers published ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rapid Communications In Mass Spectrometry
''Rapid Communications in Mass Spectrometry'' (''RCM'') is a biweekly peer-reviewed scientific journal published since 1987 by John Wiley & Sons. It covers research on all aspects of mass spectrometry. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 2.419. RCM Beynon Prize To mark the 80th birthday of John H. Beynon John H. Beynon FRS (29 December 1923 – 24 August 2015) was a Welsh chemist and physicist known for his work in mass spectrometry. Education and military service Beynon was born in the Welsh coal-mining town of Ystalyfera and was the older o ..., the founding Editor of RCM, in 2004 an annual award was established in his honour by the publishers. The award is made on the recommendation of an ad hoc Sub-committee of the Editorial Board of RCM. References External links * Mass spectrometry journals Publications established in 1987 Wiley (publisher) academic journals {{biochem-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Koichi Tanaka
is a Japanese electrical engineer who shared the Nobel Prize in Chemistry in 2002 for developing a novel method for mass spectrometric analyses of biological macromolecules with John Bennett Fenn and Kurt Wüthrich (the latter for work in NMR spectroscopy). Early life and education Tanaka was born and raised in Toyama, Japan, his biological mother died one month after he was born. Tanaka graduated from Tohoku University with a bachelor's degree in electrical engineering in 1983, afterward he joined Shimadzu Corporation, where he engaged in the development of mass spectrometers. Soft laser desorption For mass spectrometry analyses of a macromolecule, such as a protein, the analyte must be ionized and vaporized by laser irradiation. The problem is that the direct irradiation of an intense laser pulse on a macromolecule causes cleavage of the analyte into tiny fragments and the loss of its structure. In February 1985, Tanaka found that by using a mixture of ultra fine metal pow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biopolymer
Biopolymers are natural polymers produced by the cells of living organisms. Like other polymers, biopolymers consist of monomeric units that are covalently bonded in chains to form larger molecules. There are three main classes of biopolymers, classified according to the monomers used and the structure of the biopolymer formed: polynucleotides, polypeptides, and polysaccharides. The Polynucleotides, RNA and DNA, are long polymers of nucleotides. Polypeptides include proteins and shorter polymers of amino acids; some major examples include collagen, actin, and fibrin. Polysaccharides are linear or branched chains of sugar carbohydrates; examples include starch, cellulose and alginate. Other examples of biopolymers include natural rubbers (polymers of isoprene), suberin and lignin (complex polyphenolic polymers), cutin and cutan (complex polymers of long-chain fatty acids) and melanin. In addition to their many essential roles in living organisms, biopolymers have applications in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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