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Fontainea Picrosperma
''Fontainea picrosperma'', commonly known as the blushwood tree, is a rainforest tree in the family Euphorbiaceae endemic to Queensland in Australia, where it grows on the Atherton Tablelands. Uses An anti-cancer drug known as EBC-46 has been developed from an extract of the fruits of ''Fontainea picrosperma''. Trials have shown that it has activity against four different types of tumours, including basal-cell carcinoma Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer. It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it. It may also present as a raise ..., melanoma, squamous cell carcinoma and breast adenocarcinoma. The fruits are toxic to humans if eaten. References picrosperma Trees of Australia Malpighiales of Australia Critically endangered flora of Australia Flora of Queensland {{rosid-tree-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Euphorbiaceae
Euphorbiaceae, the spurge family, is a large family of flowering plants. In English, they are also commonly called euphorbias, which is also the name of a genus in the family. Most spurges, such as ''Euphorbia paralias'', are herbs, but some, especially in the tropics, are shrubs or trees, such as ''Hevea brasiliensis''. Some, such as ''Euphorbia canariensis'', are succulent and resemble cacti because of convergent evolution. This family has a cosmopolitan global distribution. The greatest diversity of species is in the tropics, however, the Euphorbiaceae also have many species in nontropical areas of all continents except Antarctica. Description The leaves are alternate, seldom opposite, with stipules. They are mainly simple, but where compound, are always palmate, never pinnate. Stipules may be reduced to hairs, glands, or spines, or in succulent species are sometimes absent. The plants can be monoecious or dioecious. The radially symmetrical flowers are unisexual, w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endemic
Endemism is the state of a species being found in a single defined geographic location, such as an island, state, nation, country or other defined zone; organisms that are indigenous to a place are not endemic to it if they are also found elsewhere. For example, the Cape sugarbird is found exclusively in southwestern South Africa and is therefore said to be ''endemic'' to that particular part of the world. An endemic species can be also be referred to as an ''endemism'' or in scientific literature as an ''endemite''. For example '' Cytisus aeolicus'' is an endemite of the Italian flora. '' Adzharia renschi'' was once believed to be an endemite of the Caucasus, but it was later discovered to be a non-indigenous species from South America belonging to a different genus. The extreme opposite of an endemic species is one with a cosmopolitan distribution, having a global or widespread range. A rare alternative term for a species that is endemic is "precinctive", which applies to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Queensland
) , nickname = Sunshine State , image_map = Queensland in Australia.svg , map_caption = Location of Queensland in Australia , subdivision_type = Country , subdivision_name = Australia , established_title = Before federation , established_date = Colony of Queensland , established_title2 = Separation from New South Wales , established_date2 = 6 June 1859 , established_title3 = Federation , established_date3 = 1 January 1901 , named_for = Queen Victoria , demonym = , capital = Brisbane , largest_city = capital , coordinates = , admin_center_type = Administration , admin_center = 77 local government areas , leader_title1 = Monarch , leader_name1 = Charles III , leader_title2 = Governor , leader_name2 = Jeannette Young , leader_title3 = Premier , leader_name3 = Annastacia Palaszczuk ( ALP) , legislature = Parliament of Queensland , judiciary = Supreme Court of Queensland , national_representation = Parliament of Australia , national_representation_type ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atherton Tableland
The Atherton Tableland is a fertile plateau which is part of the Great Dividing Range in Queensland, Australia. The principal river flowing across the plateau is the Barron River. It was dammed to form an irrigation reservoir named Lake Tinaroo. Tinaroo Hydro, a small 1.6 MW hydroelectric power station, is located near the spillway. Physiography This area is a distinct physiographic section of the larger North Queensland Highlands province, which in turn is part of the larger East Australian Cordillera physiographic division. South of the Tablelands is the Bellenden Ker Range. Geological history About 100 million years ago, the eastern edge of the Australian continent extended much further to the east, before tectonic forces fractured the eastern margin, pulling it apart. At the same time, slowly rising mantle material caused a doming up of the continental crust. As the eastern part of the continent broke away, it gradually sank below sea level. Since that time, the up ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
EBC-46
Tigilanol tiglate (USAN; ), sold under the brand name Stelfonta is a medication used to treat dogs with non-metastatic, skin-based (cutaneous) mast cell tumors (MCTs). The FDA is also approving Stelfonta to treat non-metastatic MCTs located under the dog's skin ( subcutaneous), in particular areas of a dog's leg. Stelfonta is injected directly into the MCT (intratumoral injection). Stelfonta works by activating a protein that spreads throughout the treated tumor, which disintegrates tumor cells. It is a tiglien-3-on derivative, with a tigliane backbone. Since the substance is obtained by extraction, impurities with other tiglian-3-one derivatives are possible. Initially, the synthesis was only used to confirm the structure and is possible via the Wender synthesis. In 2022, the Wender group reported an efficient semi-synthesis of tigilanol tiglate from phorbol (12% overall yield over 12 steps). Tigilanol tiglate was approved for use in dogs in the European Union in January 2020. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basal-cell Carcinoma
Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer. It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it. It may also present as a raised area with ulceration. Basal-cell cancer grows slowly and can damage the tissue around it, but it is unlikely to spread to distant areas or result in death. Risk factors include exposure to ultraviolet light, having lighter skin, radiation therapy, long-term exposure to arsenic and poor immune-system function. Exposure to UV light during childhood is particularly harmful. Tanning beds have become another common source of ultraviolet radiation. Diagnosis often depends on skin examination, confirmed by tissue biopsy. It remains unclear whether sunscreen affects the risk of basal-cell cancer. Treatment is typically by surgical removal. This can be by simple excision if the cancer is small; otherwise, Mohs surgery is generally recommen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melanoma
Melanoma, also redundantly known as malignant melanoma, is a type of skin cancer that develops from the pigment-producing cells known as melanocytes. Melanomas typically occur in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). In women, they most commonly occur on the legs, while in men, they most commonly occur on the back. About 25% of melanomas develop from moles. Changes in a mole that can indicate melanoma include an increase in size, irregular edges, change in color, itchiness, or skin breakdown. The primary cause of melanoma is ultraviolet light (UV) exposure in those with low levels of the skin pigment melanin. The UV light may be from the sun or other sources, such as tanning devices. Those with many moles, a history of affected family members, and poor immune function are at greater risk. A number of rare genetic conditions, such as xeroderma pigmentosum, also increase the risk. Diagnosis is by biopsy and analysis of any skin lesion ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Squamous Cell Carcinoma
Squamous-cell carcinomas (SCCs), also known as epidermoid carcinomas, comprise a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts. Common types include: * Squamous-cell skin cancer: A type of skin cancer * Squamous-cell carcinoma of the lung: A type of lung cancer * Squamous-cell thyroid carcinoma: A type of thyroid cancer * Esophageal squamous-cell carcinoma: A type of esophageal cancer * Squamous-cell carcinoma of the vagina: A type of vaginal cancer Despite sharing the name "squamous-cell carcinoma", the SCCs of different body sites can show differences in their presented symptoms, natural history, prognosis, and response to treatment. By body location Human papillomavirus infection has been associated with SCCs of the oropharynx, lung, fingers, and anogenital region. Head and neck cancer About 90% of cases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenocarcinoma
Adenocarcinoma (; plural adenocarcinomas or adenocarcinomata ) (AC) is a type of cancerous tumor that can occur in several parts of the body. It is defined as neoplasia of epithelial tissue that has glandular origin, glandular characteristics, or both. Adenocarcinomas are part of the larger grouping of carcinomas, but are also sometimes called by more precise terms omitting the word, where these exist. Thus invasive ductal carcinoma, the most common form of breast cancer, is adenocarcinoma but does not use the term in its name—however, esophageal adenocarcinoma does to distinguish it from the other common type of esophageal cancer, esophageal squamous cell carcinoma. Several of the most common forms of cancer are adenocarcinomas, and the various sorts of adenocarcinoma vary greatly in all their aspects, so that few useful generalizations can be made about them. In the most specific usage (narrowest sense), the glandular origin or traits are exocrine; endocrine gland tumors, suc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fontainea
''Fontainea'' is a genus constituting part of the plant family Euphorbiaceae. The nine currently known species grow naturally in Queensland (Qld) and New South Wales (NSW) Australia (6 spp.), New Caledonia and Vanuatu (1 sp.), and Papua New Guinea (2 spp.). Some species are commonly named blushwood. One species, '' Fontainea oraria'', the coast fontainea, is known only from 10 living plants growing on private property near Lennox Head in northern New South Wales, Australia. Its status is critically endangered. In 1870 in a European medical science doctoral thesis Édouard Marie Heckel first named this genus in honour of his supervisor Constant Aristide Fontaine (1818–1900), professor of chemistry and toxicology at Toulon, France. A compound, EBC-46, taken from the seed or other plant parts of these spp. or from '' Hylandia dockrillii'' has potential cancer-fighting properties in current research and recently published studies. The experimental drug shows promising early resul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trees Of Australia
The flora of Australia comprises a vast assemblage of plant species estimated to over 30,000 vascular and 14,000 non-vascular plants, 250,000 species of fungi and over 3,000 lichens. The flora has strong affinities with the flora of Gondwana, and below the family level has a highly endemic angiosperm flora whose diversity was shaped by the effects of continental drift and climate change since the Cretaceous. Prominent features of the Australian flora are adaptations to aridity and fire which include scleromorphy and serotiny. These adaptations are common in species from the large and well-known families Proteaceae (''Banksia''), Myrtaceae (''Eucalyptus'' - gum trees), and Fabaceae ('' Acacia'' - wattle). The arrival of humans around 50,000 years ago and the settlement by Europeans from 1788, has had a significant impact on the flora. The use of fire-stick farming by Aboriginal people led to significant changes in the distribution of plant species over time, and the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malpighiales Of Australia
The Malpighiales comprise one of the largest orders of flowering plants, containing about 36 families and more than species, about 7.8% of the eudicots. The order is very diverse, containing plants as different as the willow, violet, poinsettia, manchineel, rafflesia and coca plant, and are hard to recognize except with molecular phylogenetic evidence. It is not part of any of the classification systems based only on plant morphology. Molecular clock calculations estimate the origin of stem group Malpighiales at around 100 million years ago ( Mya) and the origin of crown group Malpighiales at about 90 Mya. The Malpighiales are divided into 32 to 42 families, depending upon which clades in the order are given the taxonomic rank of family. In the APG III system, 35 families were recognized. Medusagynaceae, Quiinaceae, Peraceae, Malesherbiaceae, Turneraceae, Samydaceae, and Scyphostegiaceae were consolidated into other families. The largest family, by far, is the Euphorbiaceae, wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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