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Flying Syringe
Flying syringe is a phrase that is used to refer to proposed, but not yet created, genetically modified mosquitoes that inject vaccines into people when they bite them. History In the 1990s, Bob Sinden of Imperial College, London, and Julian Crampton of the University of Liverpool, developed this idea and filled three related patents between 1997 and 2003. In 2008, the Gates Foundation awarded $100,000 to Hiroyuki Matsuoka of Jichi Medical University in Japan to do research on them, with a condition that any discoveries that were funded by the grant must be made available at affordable prices in the developing world. If Matsuoka proves that his idea has merit, he will be eligible for an additional $1 million of funding. ''The Washington Post'' referred to flying syringes as a "bold idea".Flying Syring ...
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Genetically Modified
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of Genetic engineering techniques, technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA is obtained by either isolating and copying the genetic material of interest using recombinant DNA methods or by Artificial gene synthesis, artificially synthesising the DNA. A Vector (molecular biology), construct is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made by Paul Berg in 1972 by combining DNA from the monkey virus SV40 with the Lambda phage, lambda virus. As well as inserting genes, the process can be used to remove, or "Gene knockout, knock out", genes. The new DNA can be inserted randomly, or Gene targeting, targeted to a specific ...
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Mosquitoes
Mosquitoes (or mosquitos) are members of a group of almost 3,600 species of small flies within the family Culicidae (from the Latin ''culex'' meaning "gnat"). The word "mosquito" (formed by ''mosca'' and diminutive ''-ito'') is Spanish for "little fly". Mosquitoes have a slender segmented body, one pair of wings, one pair of halteres, three pairs of long hair-like legs, and elongated mouthparts. The mosquito life cycle consists of egg, larva, pupa, and adult stages. Eggs are laid on the water surface; they hatch into motile larvae that feed on aquatic algae and organic material. These larvae are important food sources for many freshwater animals, such as dragonfly nymphs, many fish, and some birds such as ducks. The adult females of most species have tube-like mouthparts (called a proboscis) that can pierce the skin of a host and feed on blood, which contains protein and iron needed to produce eggs. Thousands of mosquito species feed on the blood of various hosts ⁠— v ...
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Vaccines
A vaccine is a biological preparation that provides active acquired immunity The adaptive immune system, also known as the acquired immune system, is a subsystem of the immune system that is composed of specialized, systemic cells and processes that eliminate pathogens or prevent their growth. The acquired immune system ... to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or Antigen, killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylact ...
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Human
Humans (''Homo sapiens'') are the most abundant and widespread species of primate, characterized by bipedalism and exceptional cognitive skills due to a large and complex brain. This has enabled the development of advanced tools, culture, and language. Humans are highly social and tend to live in complex social structures composed of many cooperating and competing groups, from families and kinship networks to political states. Social interactions between humans have established a wide variety of values, social norms, and rituals, which bolster human society. Its intelligence and its desire to understand and influence the environment and to explain and manipulate phenomena have motivated humanity's development of science, philosophy, mythology, religion, and other fields of study. Although some scientists equate the term ''humans'' with all members of the genus ''Homo'', in common usage, it generally refers to ''Homo sapiens'', the only extant member. Anatomically moder ...
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Julian Crampton
Julian M. Crampton (1 November 1952 – 26 June 2019) was a British biologist and academic. From 2005 to 2015, he was Vice-Chancellor of the University of Brighton. Early life and education Crampton was born on 1 November 1952. He graduated from the University of Sussex with a Bachelor of Science (BSc) degree. He undertook postgraduate research at Warwick University, and completed his Doctor of Philosophy (PhD) degree in 1978 with a doctoral thesis titled "The control of RNA synthesis in vitro". Academic career Crampton was a lecturer in molecular biology and tropical diseases at the University of Liverpool. He founded the Wolfson Unit of Molecular Genetics at the Liverpool School of Tropical Medicine in 1983. He was appointed to a personal chair in 1991 as Professor of Molecular Biology. He was made head of the newly created School of Biological Sciences in 1996, and pro-vice-chancellor for regional affairs in 2000. His research interests included the treatment of malaria, and t ...
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Gates Foundation
The Bill & Melinda Gates Foundation (BMGF), a merging of the William H. Gates Foundation and the Gates Learning Foundation, is an American private foundation founded by Bill Gates and Melinda French Gates. Based in Seattle, Washington, it was launched in 2000 and is reported as of 2020 to be the second largest charitable foundation in the world, holding $49.8 billion in assets. On his 43rd birthday, Bill Gates gave the foundation $1 billion. The primary stated goals of the foundation are to enhance healthcare and reduce extreme poverty across the world, and to expand educational opportunities and access to information technology in the U.S. Key individuals of the foundation include Bill Gates, Melinda French Gates, Warren Buffett, chief executive officer Mark Suzman, and Michael Larson. The BMGF had an endowment of approximately $50 billion . The scale of the foundation and the way it seeks to apply business techniques to giving makes it one of the leaders in venture philanthr ...
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Jichi Medical University
is a private university in Shimotsuke, Tochigi, Japan, established in 1972. In 2008 the Gates Foundation awarded $100,000 to Hiroyuki Matsuoka, a medical researcher at the university, to do research on flying syringe Flying syringe is a phrase that is used to refer to proposed, but not yet created, genetically modified mosquitoes that inject vaccines into people when they bite them. History In the 1990s, Bob Sinden of Imperial College, London, and Julian Cramp ...s.Flying Syringes and Other Bold Ideas
The Washington Post, October 23, 2008


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Japan
Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north toward the East China Sea, Philippine Sea, and Taiwan in the south. Japan is a part of the Ring of Fire, and spans Japanese archipelago, an archipelago of List of islands of Japan, 6852 islands covering ; the five main islands are Hokkaido, Honshu (the "mainland"), Shikoku, Kyushu, and Okinawa Island, Okinawa. Tokyo is the Capital of Japan, nation's capital and largest city, followed by Yokohama, Osaka, Nagoya, Sapporo, Fukuoka, Kobe, and Kyoto. Japan is the List of countries and dependencies by population, eleventh most populous country in the world, as well as one of the List of countries and dependencies by population density, most densely populated and Urbanization by country, urbanized. About three-fourths of Geography of Japan, the c ...
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Developing World
A developing country is a sovereign state with a lesser developed industrial base and a lower Human Development Index (HDI) relative to other countries. However, this definition is not universally agreed upon. There is also no clear agreement on which countries fit this category. The term low and middle-income country (LMIC) is often used interchangeably but refers only to the economy of the countries. The World Bank classifies the world's economies into four groups, based on gross national income per capita: high, upper-middle, lower-middle, and low income countries. Least developed countries, landlocked developing countries and small island developing states are all sub-groupings of developing countries. Countries on the other end of the spectrum are usually referred to as high-income countries or developed countries. There are controversies over this term's use, which some feel it perpetuates an outdated concept of "us" and "them". In 2015, the World Bank declared that ...
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The Washington Post
''The Washington Post'' (also known as the ''Post'' and, informally, ''WaPo'') is an American daily newspaper published in Washington, D.C. It is the most widely circulated newspaper within the Washington metropolitan area and has a large national audience. Daily broadsheet editions are printed for D.C., Maryland, and Virginia. The ''Post'' was founded in 1877. In its early years, it went through several owners and struggled both financially and editorially. Financier Eugene Meyer purchased it out of bankruptcy in 1933 and revived its health and reputation, work continued by his successors Katharine and Phil Graham (Meyer's daughter and son-in-law), who bought out several rival publications. The ''Post'' 1971 printing of the Pentagon Papers helped spur opposition to the Vietnam War. Subsequently, in the best-known episode in the newspaper's history, reporters Bob Woodward and Carl Bernstein led the American press's investigation into what became known as the Watergate scandal ...
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Hunter-seeker
This is a list of terminology used in the fictional Dune (franchise), ''Dune'' universe created by Frank Herbert, the primary source being "Terminology of the Imperium", the glossary contained in the novel ''Dune (novel), Dune'' (1965). ''Dune'' word construction could be classified into three domains of vocabulary, each marked with its own neology: the names and terms related to the politics and culture of the Galactic Empire, the names and terms characteristic of the mystic sodality of the Bene Gesserit, and the barely displaced Arabic of the Fremen language. Fremen share vocabulary for Arrakis, Arrakeen phenomena with the Empire, but use completely different vocabulary for Bene Gesserit-implanted Messianism, messianic religion. Due to the similarities between some of Herbert's terms and ideas and actual words and concepts in the Arabic language, Arabic and Hebrew languages as well as the series' "Islamic Subtext, undertones" and themes a Middle Eastern influence on Herbert's ...
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Vaccination
Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating the body's adaptive immunity, they help prevent sickness from an infectious disease. When a sufficiently large percentage of a population has been vaccinated, herd immunity results. Herd immunity protects those who may be immunocompromised and cannot get a vaccine because even a weakened version would harm them. The effectiveness of vaccination has been widely studied and verified. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the elimination of diseases such as polio and tetanus from much of the world. However, some diseases, such as measles outbreaks in America, have seen rising cases due to relative ...
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