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Fever (Cook Novel)
''Fever'' is a 1982 novel by Robin Cook (novelist), Robin Cook and is in the category of Thriller (genre), medical thriller. Plot Set mainly in the Boston area and in rural New Hampshire, its main characters are a 12-year-old girl, Michelle Martel, with leukemia and her father, Charles Martel, a former allergist turned cancer researcher, as well as her stepmother Cathryn and her two older brothers, Chuck and Jean-Paul. After falling ill one winter morning, Michelle is hospitalized, diagnosed with acute myelogenous leukemia, acute myeloblastic leukemia, and given experimentally high doses of chemotherapy, to which her father objects, since it has no effect on her leukemia and weakens her with side effects. Cathryn, a former receptionist at the fictional Weinberger Institute in Cambridge, Massachusetts, where Charles has worked since turning to cancer research, has little medical knowledge and only wants what is best for her stepchildren, and feels torn between her husband and Mi ...
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Robin Cook (novelist)
Robert Brian "Robin" Cook (born May 4, 1940)Stookey, Lorena Laura (1996). ''Robin Cook: A Critical Companion'', Westport, Connecticut, London: Greenwood Press. is an American physician and novelist who writes about medicine and topics affecting public health. He is best known for combining medical writing with the thriller genre. Many of his books have been bestsellers on ''The New York Times'' Best Seller List. Several of his books have also been featured in ''Reader's Digest''. His books have sold nearly 400 million copies worldwide. Early life and career Cook was born in Brooklyn, New York City, and grew up in Woodside, Queens. He moved to Leonia, New Jersey when he was eight, where he could first have the "luxury" of having his own room. He graduated from Wesleyan University and Columbia University College of Physicians and Surgeons, and finished his postgraduate medical training at Harvard. Cook ran the Cousteau Society's blood-gas lab in the south of France. He lat ...
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Acute Myelogenous Leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. Occasionally, spread may occur to the brain, skin, or gums. As an acute leukemia, AML progresses rapidly, and is typically fatal within weeks or months if left untreated. Risk factors include smoking, previous chemotherapy or radiation therapy, myelodysplastic syndrome, and exposure to the chemical benzene. The underlying mechanism involves replacement of normal bone marrow with leukemia cells, which results in a drop in red blood cells, platelets, and normal white blood cells. Diagnosis is generally based on bone marrow aspiration and specific blood tests. AML has several subtypes for which treatments and outcomes may vary. The first-l ...
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Novels By Robin Cook
A novel is a relatively long work of narrative fiction, typically written in prose and published as a book. The present English word for a long work of prose fiction derives from the for "new", "news", or "short story of something new", itself from the la, novella, a singular noun use of the neuter plural of ''novellus'', diminutive of ''novus'', meaning "new". Some novelists, including Nathaniel Hawthorne, Herman Melville, Ann Radcliffe, John Cowper Powys, preferred the term "romance" to describe their novels. According to Margaret Doody, the novel has "a continuous and comprehensive history of about two thousand years", with its origins in the Ancient Greek and Roman novel, in Chivalric romance, and in the tradition of the Italian renaissance novella.Margaret Anne Doody''The True Story of the Novel'' New Brunswick, NJ: Rutgers University Press, 1996, rept. 1997, p. 1. Retrieved 25 April 2014. The ancient romance form was revived by Romanticism, especially the historica ...
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1982 American Novels
__NOTOC__ Year 198 (CXCVIII) was a common year starting on Sunday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Sergius and Gallus (or, less frequently, year 951 ''Ab urbe condita''). The denomination 198 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire *January 28 **Publius Septimius Geta, son of Septimius Severus, receives the title of Caesar. **Caracalla, son of Septimius Severus, is given the title of Augustus. China *Winter – Battle of Xiapi: The allied armies led by Cao Cao and Liu Bei defeat Lü Bu; afterward Cao Cao has him executed. By topic Religion * Marcus I succeeds Olympianus as Patriarch of Constantinople (until 211). Births * Lu Kai (or Jingfeng), Chinese official and general (d. 269) * Quan Cong, Chinese general and advisor (d. ...
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Plastic Recycling
Plastic recycling is the reprocessing of plastic waste into new products. When performed correctly, this can reduce dependence on landfill, conserve resources and protect the environment from plastic pollution and greenhouse gas emissions. Although recycling rates are increasing, they lag behind those of other recoverable materials, such as aluminium, glass and paper. Since the beginning of plastic production in the 20th century, until 2015, the world has produced some 6.3 billion tonnes of plastic waste, only 9% of which has been recycled, and only ~1% has been recycled more than once. Additionally, 12% was incinerated and the remaining 79% disposed of to landfill or to the environment including the sea. Recycling is necessary because almost all plastic is non-biodegradable and thus builds-up in the environment, where it can cause harm. For example, approximately 8 million tons of waste plastic enter the Earth's oceans every year, causing damage to the aquatic ecosystem and ...
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Benzene
Benzene is an organic chemical compound with the molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar ring with one hydrogen atom attached to each. Because it contains only carbon and hydrogen atoms, benzene is classed as a hydrocarbon. Benzene is a natural constituent of petroleum and is one of the elementary petrochemicals. Due to the cyclic continuous pi bonds between the carbon atoms, benzene is classed as an aromatic hydrocarbon. Benzene is a colorless and highly flammable liquid with a sweet smell, and is partially responsible for the aroma of gasoline. It is used primarily as a precursor to the manufacture of chemicals with more complex structure, such as ethylbenzene and cumene, of which billions of kilograms are produced annually. Although benzene is a major industrial chemical, it finds limited use in consumer items because of its toxicity. History Discovery The word "''benzene''" derives from "''gum benzoin''" (benzoin res ...
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Aplastic Anemia
Aplastic anemia is a cancer in which the body fails to make blood cells in sufficient numbers. Blood cells are produced in the bone marrow by stem cells that reside there. Aplastic anemia causes a deficiency of all blood cell types: red blood cells, white blood cells, and platelets. It occurs most frequently in people in their teens and twenties but is also common among the elderly. It can be caused by heredity, immune disease, or exposure to chemicals, drugs, or radiation. However, in about half of cases, the cause is unknown. Aplastic anemia can be definitively diagnosed by bone marrow biopsy. Normal bone marrow has 30–70% blood stem cells, but in aplastic anemia, these cells are mostly gone and are replaced by fat. First-line treatment for aplastic anemia consists of immunosuppressive drugs—typically either anti-lymphocyte globulin or anti-thymocyte globulin—combined with corticosteroids, chemotherapy, and ciclosporin. Hematopoietic stem cell transplantation is a ...
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Cambridge, Massachusetts
Cambridge ( ) is a city in Middlesex County, Massachusetts, United States. As part of the Boston metropolitan area, the cities population of the 2020 U.S. census was 118,403, making it the fourth most populous city in the state, behind Boston, Worcester, and Springfield. It is one of two de jure county seats of Middlesex County, although the county's executive government was abolished in 1997. Situated directly north of Boston, across the Charles River, it was named in honor of the University of Cambridge in England, once also an important center of the Puritan theology embraced by the town's founders. Harvard University, the Massachusetts Institute of Technology (MIT), Lesley University, and Hult International Business School are in Cambridge, as was Radcliffe College before it merged with Harvard. Kendall Square in Cambridge has been called "the most innovative square mile on the planet" owing to the high concentration of successful startups that have emerged in the vicinity ...
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ...
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Allergist
An allergist is a physician specially trained to manage and treat allergies, asthma and the other allergic diseases. They may also be called immunologists. Becoming an allergist Becoming an allergist/immunologist requires completion of at least nine years of training. After completing medical school and graduating with a medical degree, a physician will then undergo three years of training in internal medicine (to become an internist) or pediatrics (to become a pediatrician). Once physicians have finished training in one of these specialties, they must pass the exam of either the American Board of Pediatrics (ABP) or the American Board of Internal Medicine (ABIM). Internists or pediatricians who wish to focus on the sub-specialty of allergy-immunology then complete at least an additional two years of study, called a fellowship, in an allergy/immunology training program. Allergist/immunologists who are listed as ABAI-certified have successfully passed the certifying examination ...
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Thriller (genre)
Thriller is a genre of fiction, having numerous, often overlapping subgenres. Thrillers are characterized and defined by the mood (psychology), moods they elicit, giving viewers heightened feelings of suspense, Psychomotor agitation, excitement, Surprise (emotion), surprise, anticipation (emotion), anticipation and anxiety. Successful examples of thrillers are Alfred Hitchcock filmography, the films of Alfred Hitchcock. Thrillers generally keep the audience on the "edge of their seats" as the plot builds towards a climax (narrative), climax. The cover-up of important information is a common element. Literary devices such as red herrings, plot twists, unreliable narrators, and cliffhangers are used extensively. A thriller is often a villain-driven plot, whereby they present obstacles that the protagonist must overcome. The most common genres that overlap with the thriller genre include crime fiction, crime, horror fiction, horror and detective fiction. Characteristics Writer Vla ...
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Leukemia
Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ''leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia— acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myeloi ...
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