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Fermenting Wine
The process of fermentation in winemaking turns grape juice into an alcoholic beverage. During fermentation, yeasts transform sugars present in the juice into ethanol and carbon dioxide (as a by-product). In winemaking, the temperature and speed of fermentation are important considerations as well as the levels of oxygen present in the must at the start of the fermentation. The risk of stuck fermentation and the development of several wine faults can also occur during this stage, which can last anywhere from 5 to 14 days for ''primary fermentation'' and potentially another 5 to 10 days for a '' secondary fermentation''. Fermentation may be done in stainless steel tanks, which is common with many white wines like Riesling, in an open wooden vat, inside a wine barrel and inside the wine bottle itself as in the production of many sparkling wines. History The natural occurrence of fermentation means it was probably first observed long ago by humans.H. Johnson: ''Vintage: The Story ...
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Sparkling Wine
Sparkling wine is a wine with significant levels of carbon dioxide in it, making it fizzy. While the phrase commonly refers to champagne, European Union countries legally reserve that term for products exclusively produced in the Champagne region of France. Sparkling wine is usually either white or rosé, but there are examples of red sparkling wines such as the Italian Brachetto, Bonarda and Lambrusco, and the Australian sparkling Shiraz. The sweetness of sparkling wine can range from very dry ''brut'' styles to sweeter ''doux'' varieties (French for 'hard' and 'soft', respectively).J. Robinson (ed) ''"The Oxford Companion to Wine"'' Third Edition pp 656–660, Oxford University Press 2006 . The sparkling quality of these wines comes from its carbon dioxide content and may be the result of natural fermentation, either in a bottle, as with the traditional method, in a large tank designed to withstand the pressures involved (as in the Charmat process), or as a result of simp ...
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Candida (genus)
''Candida'' is a genus of yeasts and is the most common cause of fungal infections worldwide. Many species are harmless commensals or endosymbionts of hosts including humans; however, when mucosal barriers are disrupted or the immune system is compromised they can invade and cause disease, known as an opportunistic infection. Candida is located on most mucosal surfaces and mainly the gastrointestinal tract, along with the skin. ''Candida albicans'' is the most commonly isolated species and can cause infections (candidiasis or thrush) in humans and other animals. In winemaking, some species of ''Candida'' can potentially spoil wines. Many species are found in gut flora, including ''C. albicans'' in mammalian hosts, whereas others live as endosymbionts in insect hosts. Systemic infections of the bloodstream and major organs ( candidemia or invasive candidiasis), particularly in patients with an impaired immune system (immunocompromised), affect over 90,000 people a year in the U ...
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Genus
Genus ( plural genera ) is a taxonomic rank used in the biological classification of extant taxon, living and fossil organisms as well as Virus classification#ICTV classification, viruses. In the hierarchy of biological classification, genus comes above species and below family (taxonomy), family. In binomial nomenclature, the genus name forms the first part of the binomial species name for each species within the genus. :E.g. ''Panthera leo'' (lion) and ''Panthera onca'' (jaguar) are two species within the genus ''Panthera''. ''Panthera'' is a genus within the family Felidae. The composition of a genus is determined by taxonomy (biology), taxonomists. The standards for genus classification are not strictly codified, so different authorities often produce different classifications for genera. There are some general practices used, however, including the idea that a newly defined genus should fulfill these three criteria to be descriptively useful: # monophyly – all descendants ...
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Yeast On Grapes
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitute 1% of all described fungal species. Yeasts are unicellular organisms that evolved from multicellular ancestors, with some species having the ability to develop multicellular characteristics by forming strings of connected budding cells known as pseudohyphae or false hyphae. Yeast sizes vary greatly, depending on species and environment, typically measuring 3–4  µm in diameter, although some yeasts can grow to 40 µm in size. Most yeasts reproduce asexually by mitosis, and many do so by the asymmetric division process known as budding. With their single-celled growth habit, yeasts can be contrasted with molds, which grow hyphae. Fungal species that can take both forms (depending on temperature or other conditions) are called ...
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Single-use Bioreactor
A single-use bioreactor or ''disposable bioreactor'' is a bioreactor with a disposable bag instead of a culture vessel. Typically, this refers to a bioreactor in which the lining in contact with the cell culture will be plastic, and this lining is encased within a more permanent structure (typically, either a rocker or a cuboid or cylindrical steel support). Commercial single-use bioreactors have been available since the end of the 1990s and are now made by several well-known producers ( See below) . Single-use at bioreactors Single-use bioreactors are widely used in the field of mammalian cell culture and are now rapidly replacing conventional bioreactors. Instead of a culture vessel made from stainless steel or glass, a single-use bioreactor is equipped with a disposable bag. The disposable bag is usually made of a three-layer plastic foil. One layer is made from Polyethylene terephthalate or LDPE to provide mechanical stability. A second layer made using PVA or PVC acts ...
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Jakub Karol Parnas
Jakub Karol Parnas, also known as Yakov Oskarovich Parnas (russian: Яков Оскарович Парнас) (January 16, 1884 – January 29, 1949) was a prominent Polish–Soviet biochemist who contributed to the discovery of the Embden–Meyerhof–Parnas pathway, together with Otto Fritz Meyerhof and Gustav Georg Embden. He became a Soviet activist after the annexation of Western Ukraine in 1939. He was arrested during the Jewish Anti-Fascist Committee affair in 1949 and died in the prison, reportedly of heart attack. Biography Parnas was born in 1884 in Tarnopol, at that time part of the Austro-Hungarian Empire, in the province of Galicia (now split between Poland and Ukraine), to Jewish parents. He graduated from the Royal Technical College of Charlottenburg in 1904. From 1920 to 1941, he was head of the Institute of the Medical Chemistry at Lviv University. He traveled across Europe, collaborating with universities in Cambridge, Naples, Strasbourg, Ghent and Zuri ...
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Otto Fritz Meyerhof
Otto Fritz Meyerhof (; April 12, 1884 – October 6, 1951) was a German physician and biochemist who won the 1922 Nobel Prize in Physiology and Medicine. Biography Otto Fritz Meyerhof was born in Hannover, at Theaterplatz 16A (now:Rathenaustrasse 16A), the son of wealthy Jewish parents. In 1888, his family moved to Berlin, where Otto spent most of his childhood, and where he started his study of medicine. He continued these studies in Strasbourg and Heidelberg, from which he graduated in 1909, with a work titled "Contributions to the Psychological Theory of Mental Illness". In Heidelberg, he met Hedwig Schallenberg. They married in 1914 and became parents of a daughter, Bettina, and two sons, Gottfried (who referred, after emigration, to himself as Geoffrey) as well as Walter. In 1912, Otto Meyerhof moved to the University of Kiel, where he received a professorship in 1918. In 1922, he was awarded the Nobel Prize in Medicine, with Archibald Vivian Hill, for his work on muscle me ...
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Gustav Embden
Gustav Georg Embden (10 November 1874 – 25 July 1933) was a German physiological chemist. Background Gustav Embden was a son of the Hamburg lawyer and politician George Heinrich Embden. His grandmother Charlotte Heine was a well-known salonnière and a sister of the poet Heinrich Heine. Education and career Embden initially studied in Freiburg, Strasbourg, Munich, Berlin, and Zurich under the famous physiologists of his time, including Johannes von Kries, Franz Hofmeister, Gaule, Paul Ehrlich, and Julius Richard Ewald. In 1904, he became the director of the chemistry laboratory of the medical clinic at the Frankfurt-Sachsenhausen municipal hospital. His research here helped to build the clinic into the Physiological Institute by 1907 and into the University Institute for Vegetative Physiology in 1914. In the same year, he retained his directorship and started teaching at the University of Frankfurt am Main. Embden served as the rector of the university from 1925 to 1926. ...
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Glycolysis
Glycolysis is the metabolic pathway that converts glucose () into pyruvate (). The free energy released in this process is used to form the high-energy molecules adenosine triphosphate (ATP) and reduced nicotinamide adenine dinucleotide (NADH). Glycolysis is a sequence of ten reactions catalyzed by enzymes. Glycolysis is a metabolic pathway that does not require oxygen (In anaerobic conditions pyruvate is converted to lactic acid). The wide occurrence of glycolysis in other species indicates that it is an ancient metabolic pathway. Indeed, the reactions that make up glycolysis and its parallel pathway, the pentose phosphate pathway, occur in the oxygen-free conditions of the Archean oceans, also in the absence of enzymes, catalyzed by metal. In most organisms, glycolysis occurs in the liquid part of cells, the cytosol. The most common type of glycolysis is the ''Embden–Meyerhof–Parnas (EMP) pathway'', which was discovered by Gustav Embden, Otto Meyerhof, and Jakub Karol ...
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Louis Pasteur
Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist and microbiologist renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization, the latter of which was named after him. His research in chemistry led to remarkable breakthroughs in the understanding of the causes and preventions of diseases, which laid down the foundations of hygiene, public health and much of modern medicine. His works are credited to saving millions of lives through the developments of vaccines for rabies and anthrax. He is regarded as one of the founders of modern bacteriology and has been honored as the "father of bacteriology" and the "father of microbiology" (together with Robert Koch; the latter epithet also attributed to Antonie van Leeuwenhoek). Pasteur was responsible for disproving the doctrine of spontaneous generation. Under the auspices of the French Academy of Sciences, his experiment demonstrated that in sterilized ...
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