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FAKHRAVAC
FAKHRAVAC ( fa, واکسن فخرا) is a COVID-19 vaccine developed in Iran by the Organization of Defensive Innovation and Research, a subsidiary of Iran's Ministry of Defense. It's the third Iranian COVID-19 vaccine reaching clinical trials. It's currently in phase III. It has received emergency use authorization in Iran on 9 September 2021. The vaccine is named after the Iranian nuclear scientist Mohsen Fakhrizadeh. According to the Iranian authorities, he was working on a vaccine in response to the COVID-19 pandemic in Iran. Fakhrizadeh was assassinated in November 2020 in an attack Iran and US intelligence attributed to Israel. Medical uses It requiring two doses given by intramuscular injection 3 weeks apart. Pharmacology FAKHRAVAC is an inactivated virus-based vaccine. Manufacturing In August 2021, production capacity of the vaccine is reported to be 1 million dose per month and is planned to be "multiplied in a few months ". In October 2021, the production h ...
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Mohsen Fakhrizadeh
Mohsen Fakhrizadeh Mahabadi ( fa, محسن فخری‌زاده مهابادی ;195827 November 2020) was an Iranian nuclear physicist and scientist. He was regarded as the chief of Iran's nuclear program. Born in Qom in 1958, Fakhrizadeh joined the Islamic Revolutionary Guard Corps after the Iranian revolution of 1979. He attended Shahid Beheshti University and later received a PhD from the University of Isfahan. Beginning in 1991, he was a physics professor at Imam Hossein University. Fakhrizadeh led the Organization of Defensive Innovation and Research and the Green Salt Project. Due to Fakhrizadeh's affiliation with the Iranian nuclear program, both the United Nations Security Council and the United States ordered his assets frozen in the mid-2000s. In the early 2010s, he established and led the Organization of Defensive Innovation and Research, which, according to the United States, conducted research potentially useful for nuclear weapons. Iran has denied that its nuclear ...
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COVID-19 Vaccine
A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). This knowledge accelerated the development of various vaccine platforms during early 2020. The initial focus of SARS-CoV-2 vaccines was on preventing symptomatic, often severe illness. In January 2020, the SARS-CoV-2 genetic sequence data was shared through GISAID, and by March 2020, the global pharmaceutical industry announced a major commitment to address COVID19. In 2020, the first COVID19 vaccines were developed and made available to the public through emergency authorizations and conditional approvals. Initially, most COVID19 vaccines were two ...
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Organization Of Defensive Innovation And Research
The Organization of Defensive Innovation and Research or S.P.N.D. ( fa, سازمان پژوهش‌های نوین دفاعی, transliterated Sazman-e Pazhouheshhaye Novin-e Defa’i and abbreviated سازمان سپند) is a research and development agency of the Iran's Ministry of Defence responsible for the development of emerging technologies for use by the military. According to Iranian medias, it is the Iranian counterpart of the American DARPA. The organization was reportedly established and led by Mohsen Fakhrizadeh until his assassination outside Tehran on November 26, 2020. According to the Israeli officials, later backed up by American intelligence officials, it was tasked with the research and development of nuclear weapons, and took over some of the activities of the AMAD Project. It has been sanctioned by the United States Department of State and United States Department of the Treasury. According to the US, it was established in 2011. Amid the COVID-19 pandemic in ...
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COVID-19 Vaccine Clinical Research
COVID-19 vaccine clinical research uses clinical research to establish the characteristics of COVID-19 COVID-19 vaccine, vaccines. These characteristics include #Efficacy, efficacy, #Effectiveness, effectiveness and safety. , 40 vaccines are authorized by at least one national regulation of therapeutic goods, regulatory authority for public use: * one DNA vaccine: ZyCoV-D * four RNA vaccines: Pfizer–BioNTech COVID-19 vaccine, Pfizer–BioNTech, Moderna COVID-19 vaccine, Moderna, Walvax COVID-19 vaccine, Walvax, and HGC019, Gemcovac * twelve inactivated vaccines: Chinese Academy of Medical Sciences COVID-19 vaccine, Chinese Academy of Medical Sciences, CoronaVac, Covaxin, CoviVac (Russia COVID-19 vaccine), CoviVac, COVIran Barekat, FAKHRAVAC, Minhai COVID-19 vaccine, Minhai-Kangtai, QazCovid-in, QazVac, Sinopharm Sinopharm BIBP COVID-19 vaccine, BIBP, Sinopharm WIBP COVID-19 vaccine, WIBP, Turkovac, and Valneva COVID-19 vaccine, VLA2001. * six viral vector vaccines: Sputnik Li ...
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Pharmaceuticals In Iran
''For health issues in Iran see Health in Iran.'' Healthcare in Iran is based on three pillars: the public-governmental system, the private sector, and NGOs. The healthcare and medical sector's market value in Iran was almost US$24 billion in 2002 and is forecast to rise to US$96 billion in 2017. With a population of 80 million (2017), Iran is one of the most populous countries in West Asia. The country faces the common problem of other young demographic nations in the region, which is keeping pace with growth of an already huge demand for various public services. The young population will soon be old enough to start new families, which will boost the population growth rate and subsequently the need for public health infrastructures and services. Total healthcare spending is expected to rise from $24.3 billion in 2008, to $96 billion by 2017, reflecting the increasing demand on medical services. Total health spending was equivalent to 6% of GDP in Iran in 2017. About 90% of Irania ...
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Severe Acute Respiratory Syndrome Coronavirus 2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a Novel coronavirus, provisional name, 2019 novel coronavirus (2019-nCoV), and has also been called the human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization declared the outbreak a public health emergency of international concern on January 30, 2020, and a pandemic on March 11, 2020. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is Contagious disease, contagious in humans. SARS‑CoV‑2 is a virus of the species ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV), related to the Severe acute respiratory syndrome coronavirus 1, SARS-CoV-1 virus that caused the 2002–2004 SARS outbreak. Despite its close relation to SARS-CoV-1, i ...
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Inactivated Vaccine
An inactivated vaccine (or killed vaccine) is a vaccine consisting of virus particles, bacteria, or other pathogens that have been grown in culture and then killed to destroy disease-producing capacity. In contrast, live vaccines use pathogens that are still alive (but are almost always attenuated, that is, weakened). Pathogens for inactivated vaccines are grown under controlled conditions and are killed as a means to reduce infectivity and thus prevent infection from the vaccine. Inactivated vaccines were first developed in the late 1800s and early 1900s for cholera, plague, and typhoid. Today, inactivated vaccines exist for many pathogens, including influenza, polio (IPV), rabies, hepatitis A and pertussis. Because inactivated pathogens tend to produce a weaker response by the immune system than live pathogens, immunologic adjuvants and multiple "booster" injections may be required in some vaccines to provide an effective immune response against the pathogen. Attenuated vacci ...
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Iranian COVID-19 Vaccines
Iranian may refer to: * Iran, a sovereign state * Iranian peoples, the speakers of the Iranian languages. The term Iranic peoples is also used for this term to distinguish the pan ethnic term from Iranian, used for the people of Iran * Iranian languages, a branch of the Indo-Iranian languages * Iranian diaspora, Iranian people living outside Iran * Iranian architecture, architecture of Iran and parts of the rest of West Asia * Iranian foods, list of Iranian foods and dishes * Iranian.com, also known as ''The Iranian'' and ''The Iranian Times'' See also * Persian (other) * Iranians (other) * Languages of Iran * Ethnicities in Iran * Demographics of Iran * Indo-Iranian languages * Irani (other) * List of Iranians This is an alphabetic list of notable people from Iran or its historical predecessors. In the news * Ali Khamenei, supreme leader of Iran * Ebrahim Raisi, president of Iran, former Chief Justice of Iran. * Hassan Rouhani, former president o ...
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Clinical Trials
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ...
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Sinopharm BIBP COVID-19 Vaccine
The Sinopharm BIBP COVID-19 vaccine, also known as BBIBP-CorV, the Sinopharm COVID-19 vaccine, or BIBP vaccine, is one of two whole inactivated virus COVID-19 vaccines developed by Sinopharm's Beijing Institute of Biological Products (sometimes written as Beijing Bio-Institute of Biological Products, resulting in the two different acronyms BBIBP and BIBP for the same vaccine). It completed Phase III trials in Argentina, Bahrain, Egypt, Morocco, Pakistan, Peru, and the United Arab Emirates (UAE) with over 60,000 participants. BBIBP-CorV shares similar technology with CoronaVac and Covaxin, other inactivated virus vaccines for COVID-19. Its product name is SARS-CoV-2 Vaccine (Vero Cell), not to be confused with the similar product name of CoronaVac. Peer-reviewed results published in ''JAMA'' of Phase III trials in United Arab Emirates and Bahrain showed that the vaccine is 78.1% effective against symptomatic cases and 100% against severe cases (21 cases in vaccinated group vs. 95 c ...
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COVID-19 Pandemic In Iran
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, loss of smell, and loss of taste. Symptoms may begin one to fourteen days after exposure to the virus. At least a third of people who are infected do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure, shock, or multiorgan dysfunction). Older people are at a higher risk of developing severe ...
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Intramuscular Injection
Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle. In medicine, it is one of several methods for parenteral administration of medications. Intramuscular injection may be preferred because muscles have larger and more numerous blood vessels than subcutaneous tissue, leading to faster absorption than subcutaneous or intradermal injections. Medication administered via intramuscular injection is not subject to the first-pass metabolism effect which affects oral medications. Common sites for intramuscular injections include the deltoid muscle of the upper arm and the gluteal muscle of the buttock. In infants, the vastus lateralis muscle of the thigh is commonly used. The injection site must be cleaned before administering the injection, and the injection is then administered in a fast, darting motion to decrease the discomfort to the individual. The volume to be injected in the muscle is usually limited to 2–5 milliliters, depending on in ...
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