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Evandro Chagas Institute
The Evandro Chagas Institute ( Portuguese ''Instituto Evandro Chagas'', or IEC) is a non-profit organization which promotes public health in Brazil named after Evandro Chagas. History In the 1940s fisherman Henrique Penna from the Rockefeller Foundation in Rio de Janeiro reported that he had discovered cases of leishmaniasis in Brazil's countryside. The disease had not been previously detected in Brazil, and as a response, Carlos Chagas of the Oswaldo Cruz Institute organized a commission leishmaniasis to be headed by his son Evandro Chagas. In 1938 this commission became the ''Instituto de Pathologia Experimental do Norte'', or Northern Institution for Experimental Pathology (IPEN), with a mission to study leishmaniasis and other regional diseases. In 1940 Evandro Chagas died in a plane crash. To acknowledge his work as a scientist, the government changed the name of the former IPEN into the Evandro Chagas Institute. Research The IEC organized local volunteers to participa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Portuguese Language
Portuguese ( or, in full, ) is a western Romance language of the Indo-European language family, originating in the Iberian Peninsula of Europe. It is an official language of Portugal, Brazil, Cape Verde, Angola, Mozambique, Guinea-Bissau and São Tomé and Príncipe, while having co-official language status in East Timor, Equatorial Guinea, and Macau. A Portuguese-speaking person or nation is referred to as " Lusophone" (). As the result of expansion during colonial times, a cultural presence of Portuguese speakers is also found around the world. Portuguese is part of the Ibero-Romance group that evolved from several dialects of Vulgar Latin in the medieval Kingdom of Galicia and the County of Portugal, and has kept some Celtic phonology in its lexicon. With approximately 250 million native speakers and 24 million L2 (second language) speakers, Portuguese has approximately 274 million total speakers. It is usually listed as the sixth-most spoken language, the third-most sp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non-profit Organization
A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in contrast with an entity that operates as a business aiming to generate a profit for its owners. A nonprofit is subject to the non-distribution constraint: any revenues that exceed expenses must be committed to the organization's purpose, not taken by private parties. An array of organizations are nonprofit, including some political organizations, schools, business associations, churches, social clubs, and consumer cooperatives. Nonprofit entities may seek approval from governments to be tax-exempt, and some may also qualify to receive tax-deductible contributions, but an entity may incorporate as a nonprofit entity without securing tax-exempt status. Key aspects of nonprofits are accountability, trustworthiness, honesty, and openness to eve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Public Health
Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the determinants of health of a population and the threats it faces is the basis for public health. The ''public'' can be as small as a handful of people or as large as a village or an entire city; in the case of a pandemic it may encompass several continents. The concept of ''health'' takes into account physical, psychological, and social well-being.What is the WHO definition of health? from the Preamble to the Constitution of WHO as adopted by the International Health Conference, New York, 19 June - 22 July 1946; signed on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brazil
Brazil ( pt, Brasil; ), officially the Federative Republic of Brazil (Portuguese: ), is the largest country in both South America and Latin America. At and with over 217 million people, Brazil is the world's fifth-largest country by area and the seventh most populous. Its capital is Brasília, and its most populous city is São Paulo. The federation is composed of the union of the 26 States of Brazil, states and the Federal District (Brazil), Federal District. It is the largest country to have Portuguese language, Portuguese as an List of territorial entities where Portuguese is an official language, official language and the only one in the Americas; one of the most Multiculturalism, multicultural and ethnically diverse nations, due to over a century of mass Immigration to Brazil, immigration from around the world; and the most populous Catholic Church by country, Roman Catholic-majority country. Bounded by the Atlantic Ocean on the east, Brazil has a Coastline of Brazi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evandro Chagas
Evandro Serafim Lobo Chagas (August 10, 1905 – November 8, 1940) the eldest son of Carlos Chagas (1879-1934), noted physician and scientist who discovered Chagas disease, and brother of Carlos Chagas Filho (1910-2000), also a noted physician and scientist who was president of the Pontifical Academy of Sciences. In 1926 Evandro Chagas got diploma from the Faculty of Medicine of Rio de Janeiro and made residence at Hospital São Francisco de Assis and at Hospital Oswaldo Cruz. At the same time, he attended the specialization course in microbiology at the Instituto Oswaldo Cruz. In 1930 he became professor at Clinical Infectious and Tropical Diseases (in Portuguese: Clínica de Doenças Tropicais e Infecciosas) at the Faculty of Medicine of Rio de Janeiro, whose discipline was taught by his father, Carlos Chagas. To fill the vacancy, he defended as a thesis the cardiac form of American trypanosomiasis. Being one of the pioneers in the use of electrocardiography has made sign ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rockefeller Foundation
The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, after the Carnegie Corporation, the foundation was ranked as the 39th largest U.S. foundation by total giving as of 2015. By the end of 2016, assets were tallied at $4.1 billion (unchanged from 2015), with annual grants of $173 million. According to the OECD, the foundation provided US$103.8 million for development in 2019. The foundation has given more than $14 billion in current dollars. The foundation was started by Standard Oil magnate John D. Rockefeller ("Senior") and son "Junior", and their primary business advisor, Frederick Taylor Gates, on May 14, 1913, when its charter was granted by New York. The foundation has had an international reach since the 1930s and major influence on global non-governmental organizations. The World Health Organiza ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rio De Janeiro
Rio de Janeiro ( , , ; literally 'River of January'), or simply Rio, is the capital of the state of the same name, Brazil's third-most populous state, and the second-most populous city in Brazil, after São Paulo. Listed by the GaWC as a beta global city, Rio de Janeiro is the sixth-most populous city in the Americas. Part of the city has been designated as a World Heritage Site, named "Rio de Janeiro: Carioca Landscapes between the Mountain and the Sea", on 1 July 2012 as a Cultural Landscape. Founded in 1565 by the Portuguese, the city was initially the seat of the Captaincy of Rio de Janeiro, a domain of the Portuguese Empire. In 1763, it became the capital of the State of Brazil, a state of the Portuguese Empire. In 1808, when the Portuguese Royal Court moved to Brazil, Rio de Janeiro became the seat of the court of Queen Maria I of Portugal. She subsequently, under the leadership of her son the prince regent João VI of Portugal, raised Brazil to the dignity of a k ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leishmaniasis
Leishmaniasis is a wide array of clinical manifestations caused by parasites of the trypanosome genus ''Leishmania''. It is generally spread through the bite of phlebotomine sandflies, ''Phlebotomus'' and ''Lutzomyia'', and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe. The disease can present in three main ways: cutaneous, mucocutaneous, or visceral. The cutaneous form presents with skin ulcers, while the mucocutaneous form presents with ulcers of the skin, mouth, and nose. The visceral form starts with skin ulcers and later presents with fever, low red blood cell count, and enlarged spleen and liver. Infections in humans are caused by more than 20 species of ''Leishmania''. Risk factors include poverty, malnutrition, deforestation, and urbanization. All three types can be diagnosed by seeing the parasites under microscopy. Additionally, visceral disease can be diagnosed by blood tests. Leishmaniasis can be partl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carlos Chagas
Carlos Justiniano Ribeiro Chagas, or Carlos Chagas (; July 9, 1879 – November 8, 1934), was a Brazilian sanitary physician, scientist, and bacteriologist who worked as a clinician and researcher. He discovered Chagas disease, also called ''American trypanosomiasis'', in 1909, while he was working at the Oswaldo Cruz Institute in Rio de Janeiro. Chagas's work holds a unique place in the history of medicine. Working in primitive conditions, Chagas described in detail a previously-unknown infectious disease, its pathogen, vector (Triatominae), host, clinical manifestations, and epidemiology. Chagas was also the first to discover and illustrate the parasitic fungal genus ''Pneumocystis'', which later became infamous for being linked to pneumocystis pneumonia in AIDS patients. Early life Chagas was the son of José Justiniano das Chagas, a coffee farmer from Minas Gerais, and Mariana Cândida Chagas, both of Portuguese descent. After his secondary studies at Itu, São Paulo and S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oswaldo Cruz Institute
The Oswaldo Cruz Foundation ( Portuguese ''Fundação Oswaldo Cruz'', also known as FIOCRUZ) is a scientific institution for research and development in biological sciences located in Rio de Janeiro, Brazil; it is considered one of the world's main public health research institutions. It was founded by Dr. Oswaldo Cruz, a noted physician and epidemiologist. The organization started in 1898 as the Federal SeroTherapy Institute with the objective of developing serum and vaccines against the bubonic plague. It was located outside Rio de Janeiro. The institute's activities, however, changed from simple production into research and experimental medicine, especially after Oswaldo Cruz assumed its leadership in 1902. From there on, the institute became the base for memorable sanitation campaigns in an age of outbreaks and epidemics of the bubonic plague, yellow fever, and smallpox. The institute, however, was not confined to Rio de Janeiro and collaborated in the occupation of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IPrEx
iPrEx (from es, Iniciativa Profilaxis Pre-Exposición, "pre-exposure prophylaxis initiative") was a phase III clinical trial to determine whether the antiretroviral medication emtricitabine/tenofovir (as tenofovir disoproxil fumarate) could safely and effectively prevent HIV acquisition through sex in men who have sex with men and transgender women. iPrEx was the first human study of an HIV prevention strategy known as pre-exposure prophylaxis, or PrEP. The study began in 2007 at four study sites in Peru and Ecuador, following three years of extensive community and stakeholder consultation. In 2008 the study expanded to seven additional sites in Brazil, South Africa, Thailand and the United States. Study sponsors iPrEx was sponsored by the US National Institutes of Health (NIH) through a grant to the Gladstone Institutes, a non-profit independent research organization affiliated to the University of California at San Francisco. Additional support for the conduct of the study w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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