Elisabeth Bik
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Elisabeth Bik
Elisabeth Margaretha Harbers-Bik (born 1966) is a Dutch microbiologist and scientific integrity consultant. Bik is known for her work detecting photo manipulation in scientific publications, and identifying over 4,000 potential cases of improper research conduct, including 400 research papers published by authors in China from a research paper mill company. Bik is the founder of Microbiome Digest, a blog with daily updates on microbiome research, and the Science Integrity Digest blog. Bik was awarded the 2021 John Maddox Prize for "outstanding work exposing widespread threats to research integrity in scientific papers". Early life and education Bik was born in the Netherlands. Since childhood, she had a good ability to spot repeating patterns. She studied at the Utrecht University, where she obtained her MSc degree and subsequently a PhD in 1996, both in microbiology. Her dissertation was about developing vaccines for new strains of ''Vibrio cholerae'' involved in cholera epi ...
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Netherlands
) , anthem = ( en, "William of Nassau") , image_map = , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of the Netherlands , established_title = Before independence , established_date = Spanish Netherlands , established_title2 = Act of Abjuration , established_date2 = 26 July 1581 , established_title3 = Peace of Münster , established_date3 = 30 January 1648 , established_title4 = Kingdom established , established_date4 = 16 March 1815 , established_title5 = Liberation Day (Netherlands), Liberation Day , established_date5 = 5 May 1945 , established_title6 = Charter for the Kingdom of the Netherlands, Kingdom Charter , established_date6 = 15 December 1954 , established_title7 = Dissolution of the Netherlands Antilles, Caribbean reorganisation , established_date7 = 10 October 2010 , official_languages = Dutch language, Dutch , languages_type = Regional languages , languages_sub = yes , languages = , languages2_type = Reco ...
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California
California is a U.S. state, state in the Western United States, located along the West Coast of the United States, Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the List of states and territories of the United States by population, most populous U.S. state and the List of U.S. states and territories by area, 3rd largest by area. It is also the most populated Administrative division, subnational entity in North America and the 34th most populous in the world. The Greater Los Angeles area and the San Francisco Bay Area are the nation's second and fifth most populous Statistical area (United States), urban regions respectively, with the former having more than 18.7million residents and the latter having over 9.6million. Sacramento, California, Sacramento is the state's capital, while Los Angeles is the List of largest California cities by population, most populous city in the state and the List of United States cities by population, ...
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Western Blot
The western blot (sometimes called the protein immunoblot), or western blotting, is a widely used analytical technique in molecular biology and immunogenetics to detect specific proteins in a sample of tissue homogenate or extract. Besides detecting the proteins, this technique is also utilized to visualize, distinguish, and quantify the different proteins in a complicated protein combination. Western blot technique uses three elements to achieve its task of separating a specific protein from a complex: separation by size, transfer of protein to a solid support, and marking target protein using a primary and secondary antibody to visualize. A synthetic or animal-derived antibody (known as the primary antibody) is created that recognizes and binds to a specific target protein. The electrophoresis membrane is washed in a solution containing the primary antibody, before excess antibody is washed off. A secondary antibody is added which recognizes and binds to the primary antibody ...
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PubPeer
PubPeer is a website that allows users to discuss and review scientific research after publication, i.e. post-publication peer review. The site has served as a whistleblowing platform, in that it highlighted shortcomings in several high-profile papers, in some cases leading to retractions and to accusations of scientific fraud, as noted by Retraction Watch. Contrary to most platforms, it allows anonymous post-publication commenting, a controversial feature which is the main factor for its success. Consequently, accusations of libel have been levelled at some of PubPeer's users; correspondingly the website now requires commentators to use only facts that can be publicly verified. See also * Journal club * JournalReview.org * Publons Publons was a commercial website that provided a free service for academics to track, verify, and showcase their peer review and editorial contributions for academic journals. It was launched in 2012 and was bought by Clarivate in 2017. It claime . ...
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Retraction Watch
Retraction Watch is a blog that reports on retractions of scientific papers and on related topics. The blog was launched in August 2010 and is produced by science writers Ivan Oransky (Former Vice President, Editorial ''Medscape'') and Adam Marcus (editor of ''Gastroenterology & Endoscopy News''). Its parent organization is the Center for Scientific Integrity. Scope Oransky and Marcus were motivated to launch ''Retraction Watch'' to increase the transparency of the retraction process. They observed that retractions of papers generally are not announced, that the reasons for retractions are not publicized, and that other researchers or the public who are unaware of the retraction may make decisions based on invalid results. Oransky described an example of a paper published in ''Proceedings of the National Academy of Sciences'' which reported a potential role for a drug against some types of breast cancers. Although the paper was later retracted, its retraction was not reported ...
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Case Western Reserve University School Of Medicine
Case Western Reserve School of Medicine (CWRU SOM, CaseMed) is the medical school of Case Western Reserve University, a private research university in Cleveland, Ohio. It is the largest biomedical research center in Ohio. History On November 1, 1843, under President George Edmond Pierce, five faculty members including Jared Potter Kirtland and John Delamater, and sixty-seven students began the first medical lectures at the Medical Department of Western Reserve College (also known as the Cleveland Medical College) in Hudson, Ohio. Kirtland and Delamater had previously been instructors at a medical college started in 1834, the Medical Department of Willoughby University of Lake Erie, which had closed in 1843 due to faculty disagreements. Other faculty from that Medical Department went on to found Willoughby Medical College of Columbus, a precursor to the Ohio State University College of Medicine. Women in Medicine In 1852, the medical school became the second in the U.S. t ...
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Image Manipulation Discovered By Elisabeth Bik
An image is a visual representation of something. It can be two-dimensional, three-dimensional, or somehow otherwise feed into the visual system to convey information. An image can be an artifact, such as a photograph or other two-dimensional picture, that resembles a subject. In the context of signal processing, an image is a distributed amplitude of color(s). In optics, the term “image” may refer specifically to a 2D image. An image does not have to use the entire visual system to be a visual representation. A popular example of this is of a greyscale image, which uses the visual system's sensitivity to brightness across all wavelengths, without taking into account different colors. A black and white visual representation of something is still an image, even though it does not make full use of the visual system's capabilities. Images are typically still, but in some cases can be moving or animated. Characteristics Images may be two or three-dimensional, such as a pho ...
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San Diego
San Diego ( , ; ) is a city on the Pacific Ocean coast of Southern California located immediately adjacent to the Mexico–United States border. With a 2020 population of 1,386,932, it is the List of United States cities by population, eighth most populous city in the United States and the county seat, seat of San Diego County, the List of the most populous counties in the United States, fifth most populous county in the United States, with 3,338,330 estimated residents as of 2019. The city is known for its mild year-round climate, natural deep-water harbor, extensive beaches and parks, long association with the United States Navy, and recent emergence as a healthcare and biotechnology development center. San Diego is the List of municipalities in California, second largest city in the U.S. state, state of California, after Los Angeles. Historically home to the Kumeyaay people, San Diego is frequently referred to as the "Birthplace of California", as it was the first site vi ...
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Sea Lion
Sea lions are pinnipeds characterized by external ear flaps, long foreflippers, the ability to walk on all fours, short and thick hair, and a big chest and belly. Together with the fur seals, they make up the family Otariidae, eared seals. The sea lions have six extant and one extinct species (the Japanese sea lion) in five genera. Their range extends from the subarctic to tropical waters of the global ocean in both the Northern and Southern Hemispheres, with the notable exception of the northern Atlantic Ocean. They have an average lifespan of 20–30 years. A male California sea lion weighs on average about and is about long, while the female sea lion weighs and is long. The largest sea lions are Steller's sea lions, which can weigh and grow to a length of . Sea lions consume large quantities of food at a time and are known to eat about 5–8% of their body weight (about ) at a single feeding. Sea lions can move around in water and at their fastest they can reach a ...
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Office Of Naval Research
The Office of Naval Research (ONR) is an organization within the United States Department of the Navy responsible for the science and technology programs of the U.S. Navy and Marine Corps. Established by Congress in 1946, its mission is to plan, foster, and encourage scientific research to maintain future naval power and preserve national security. It carries this out through funding and collaboration with schools, universities, government laboratories, nonprofit organizations, and for-profit organizations, and overseeing the Naval Research Laboratory, the corporate research laboratory for the Navy and Marine Corps. NRL conducts a broad program of scientific research, technology and advanced development. ONR Headquarters is in the Ballston neighborhood of Arlington, Virginia. ONR Global has offices overseas in Santiago, Sao Paulo, London, Prague, Singapore, and Tokyo. Overview ONR was authorized by an Act of Congress, Public Law 588, and subsequently approved by President ...
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Gut Microbiota
Gut microbiota, gut microbiome, or gut flora, are the microorganisms, including bacteria, archaea, fungi, and viruses that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota. The gut is the main location of the human microbiome. The gut microbiota has broad impacts, including effects on colonization, resistance to pathogens, maintaining the intestinal epithelium, metabolizing dietary and pharmaceutical compounds, controlling immune function, and even behavior through the gut–brain axis. The microbial composition of the gut microbiota varies across regions of the digestive tract. The colon contains the highest microbial density recorded in any habitat on Earth, representing between 300 and 1000 different species. Bacteria are the largest and to date, best studied component and 99% of gut bacteria come from about 30 or 40 species. Up to 60% of the dry mass of feces is bacteria. Over 99% of the b ...
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Oral Microbiota
Oral microbiology is the study of the microorganisms (microbiota) of the oral cavity and their interactions between oral microorganisms or with the host. The environment present in the human mouth is suited to the growth of characteristic microorganisms found there. It provides a source of water and nutrients, as well as a moderate temperature. Resident microbes of the mouth adhere to the teeth and gums to resist mechanical flushing from the mouth to stomach where acid-sensitive microbes are destroyed by hydrochloric acid. Anaerobic bacteria in the oral cavity include: ''Actinomyces'', '' Arachnia'' ('' Propionibacterium propionicus''), ''Bacteroides'', ''Bifidobacterium'', ''Eubacterium'', ''Fusobacterium'', ''Lactobacillus'', '' Leptotrichia'', ''Peptococcus'', ''Peptostreptococcus'', ''Propionibacterium'', ''Selenomonas'', ''Treponema'', and ''Veillonella''. Genera of fungi that are frequently found in the mouth include '' Candida'', ''Cladosporium'', ''Aspergillus'', ''Fusar ...
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