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EIF3S6
Eukaryotic translation initiation factor 3 subunit E (eIF3e) is a protein that in humans is encoded by the ''EIF3E'' gene. Interactions EIF3S6 has been shown to interact with: * BAT2, * COPS6 * CSN3, * EIF3A Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in translatio ..., and * TRIM27. See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * * * {{gene-8-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BAT2
Large proline-rich protein BAT2 is a protein that in humans is encoded by the ''BAT2'' gene. Function A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. There are two alternatively spliced transcripts encoding different isoforms described for this gene. Interactions BAT2 has been shown to interact with: * C1QBP, * EIF3S6, * HNRNPA1, * IFT88, * IMMT, and * UBAP2L Ubiquitin-associated protein 2-like is a protein that in humans is encoded by the ''UBAP2L'' gene. Interactions UBAP2L has been show ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COPS6
COP9 signalosome complex subunit 6 is a protein that in humans is encoded by the ''COPS6'' gene. Function The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. Interactions COPS6 has been shown to interact Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human ri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CSN3 (gene)
Kappa-casein is a protein that in humans is encoded by the ''CSN3'' gene. Interactions CSN3 (gene) has been shown to interact with EIF3S6 Eukaryotic translation initiation factor 3 subunit E (eIF3e) is a protein that in humans is encoded by the ''EIF3E'' gene. Interactions EIF3S6 has been shown to interact with: * BAT2, * COPS6 * CSN3, * EIF3A Eukaryotic translation initia .... References External links * Further reading * * * * * * * * * * * {{gene-4-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
EIF3A
Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in Eukaryotic_translation#Initiation, translation initiation in eukaryotes. Interactions EIF3A has been shown to Protein-protein interaction, interact with: * DISC1, * EIF3B, * EIF3C, * EIF3D, * EIF3EIP, * EIF3F, * EIF3G, * EIF3H, * EIF3I * EIF3J, * EIF3K, * EIF3S6, * EIF4B, * EIF4G2, and * FBXO32. See also *Eukaryotic initiation factor 3, Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * * {{gene-10-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TRIM27
Zinc finger protein RFP is a protein that in humans is encoded by the ''TRIM27'' gene. This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. Interactions TRIM27 has been shown to interact with PRAM1 and EIF3S6 Eukaryotic translation initiation factor 3 subunit E (eIF3e) is a protein that in humans is encoded by the ''EIF3E'' gene. Interactions EIF3S6 has been shown to interact with: * BAT2, * COPS6 * CSN3, * EIF3A Eukaryotic translation initia .... References Further ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
