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Eve Marder
Eve Marder is a University Professor and the Victor and Gwendolyn Beinfield Professor of Neuroscience at Brandeis University. At Brandeis, Marder is also a member of the Volen National Center for Complex Systems. Dr. Marder is known for her pioneering work on small neuronal networks which her team has interrogated via a combination of complementary experimental and theoretical techniques. Marder is particularly well known in the community for her work on neural circuits in the crustacean stomatogastric nervous system (STNS), a small network of 30 neurons. She discovered that circuits are not “hard-wired” to produce a single output or behavior, but can be reconfigured by neuromodulators to produce many outputs and behaviors while still maintaining the integrity of the circuit. Her work has revolutionized the way scientists approach the studies of neural circuits with respect to the study of structural and functional behavior. The general principles that have resulted from he ...
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Brandeis University
, mottoeng = "Truth even unto its innermost parts" , established = , type = Private research university , accreditation = NECHE , president = Ronald D. Liebowitz , provost = Carol Fierke , city = Waltham , state = Massachusetts , country = United States , endowment = $1.07 billion (2019) , students = 5,458 (2021) , undergrad = 3,591 (2021) , postgrad = 1,967 (2021) , faculty = 544 (2021) , administrative_staff = 1,314 (2021) , campus = Small City, , mascot = The Judge and Ollie the Owl (named for Justice Oliver Wendell Holmes Jr.) , sports_nickname = Judges , colors = Brandeis Blue , athletics_affiliations = , academic_affiliations = , website = , logo ...
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Eugene, Oregon
Eugene ( ) is a city in the U.S. state of Oregon. It is located at the southern end of the Willamette Valley, near the confluence of the McKenzie and Willamette rivers, about east of the Oregon Coast. As of the 2020 United States Census, Eugene had a population of 176,654 and covers city area of 44.21 sq mi (114.50 sq km). Eugene is the seat of Lane County and the state's second largest city after Portland. The Eugene-Springfield metropolitan statistical area is the 146th largest in the United States and the third largest in the state, behind those of Portland and Salem. In 2022, Eugene's population was estimated to have reached 179,887. Eugene is home to the University of Oregon, Bushnell University, and Lane Community College. The city is noted for its natural environment, recreational opportunities (especially bicycling, running/jogging, rafting, and kayaking), and focus on the arts, along with its history of civil unrest, protests, and green activism. Eugene's offi ...
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NAS Award In The Neurosciences
The NAS Award in the Neurosciences is awarded by the U.S. National Academy of Sciences "in recognition of extraordinary contributions to progress in the fields of neuroscience, including neurochemistry, neurophysiology, neuropharmacology, developmental neuroscience, neuroanatomy, and behavioral and clinical neuroscience." It was first awarded in 1988. Recipients SourceNational Academy of Sciences * Eve Marder (2019) For her body of work that has transformed the perception of neuronal circuits as static structures well-described by connectivity diagrams, to our current understanding of microcircuits as flexible and dynamic entities that efficiently balance the needs for plasticity and stability. * Mortimer Mishkin (2016) For fundamental contributions to understanding the functional organization of the primate brain, including discovery of the visual functions of inferior temporal cortex, the role of the dorsal and ventral visual pathways in spatial and object processing, and anat ...
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Princeton University
Princeton University is a private university, private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth, New Jersey, Elizabeth as the College of New Jersey, Princeton is the List of Colonial Colleges, fourth-oldest institution of higher education in the United States and one of the nine colonial colleges chartered before the American Revolution. It is one of the highest-ranked universities in the world. The institution moved to Newark, New Jersey, Newark in 1747, and then to the current site nine years later. It officially became a university in 1896 and was subsequently renamed Princeton University. It is a member of the Ivy League. The university is governed by the Trustees of Princeton University and has an endowment of $37.7 billion, the largest List of colleges and universities in the United States by endowment, endowment per student in the United States. Princeton provides undergraduate education, undergraduate and graduate education, graduate in ...
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Computational Neuroscience
Computational neuroscience (also known as theoretical neuroscience or mathematical neuroscience) is a branch of neuroscience which employs mathematical models, computer simulations, theoretical analysis and abstractions of the brain to understand the principles that govern the development, structure, physiology and cognitive abilities of the nervous system. Computational neuroscience employs computational simulations to validate and solve mathematical models, and so can be seen as a sub-field of theoretical neuroscience; however, the two fields are often synonymous. The term mathematical neuroscience is also used sometimes, to stress the quantitative nature of the field. Computational neuroscience focuses on the description of biologically plausible neurons (and neural systems) and their physiology and dynamics, and it is therefore not directly concerned with biologically unrealistic models used in connectionism, control theory, cybernetics, quantitative psychology, ...
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Neuromodulation
Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal. This modulation can last for hundreds of milliseconds to several minutes. Some of the effects of neuromodulators include: alter intrinsic firing activity, increase or decrease voltage-dependent currents, alter synaptic efficacy, increase bursting activity and reconfiguration of synaptic connectivity. Major neuromodulators in the central nervous system include: dopamine, serotonin, acetylcholine, histamine, norepinephrine, nitric oxide, and several neuropeptides. Cannabinoids can also be powerful CNS neuromodulators. Neuromodulators can be packaged into vesicles and released by neurons, secreted as hormones and delivered through the circulatory system. A neuromodulator ...
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ELife
''eLife'' is a not-for-profit, peer-reviewed, open access, scientific journal for the biomedical and life sciences. It was established at the end of 2012 by the Howard Hughes Medical Institute, Max Planck Society, and Wellcome Trust, following a workshop held in 2010 at the Janelia Farm Research Campus. Together, these organizations provided the initial funding to support the business and publishing operations. In 2016, the organizations committed US$26 million to continue publication of the journal. The current editor-in-chief is Michael Eisen (University of California, Berkeley). Editorial decisions are made largely by senior editors and members of the board of reviewing editors, all of whom are active scientists working in fields ranging from human genetics and neuroscience to biophysics, epidemiology, and ecology. Business model ''eLife'' is a non-profit organisation, but for long-term sustainability of the service, the journal asks for an article processing charge of ...
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Society For Neuroscience
The Society for Neuroscience (SfN) is a professional society, headquartered in Washington, DC, for basic scientists and physicians around the world whose research is focused on the study of the brain and nervous system. It is especially well known for its annual meeting, consistently one of the largest scientific conferences in the world. History SfN was founded in 1969 by Ralph W. Gerard and, at nearly 37,000 members, has grown to be the largest neuroscience society in the world. The stated mission of the society is to: #Advance the understanding of the brain and the nervous system. #Provide professional development activities, information, and educational resources. #Promote public information and general education about science and neuroscience. #Inform legislators and other policy makers about the implications of research for public policy, societal benefit, and continued scientific progress. Annual meeting The Society holds an annual meeting that is attended by scien ...
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United States National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scie ...
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Larry Abbott
Laurence Frederick Abbott"LAURENCE F. ABBOTT CV"
Retrieved on 31 March 2020.
(born 1950) is an American theoretical neuroscientist, who is currently the William Bloor Professor of Theoretical Neuroscience at , where he helped create the Center for Theoretical Neuroscience. He is widely regarded as one of the leaders of , and is coauthor, along with , on the first comprehensive textboo ...
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Homeostasis
In biology, homeostasis (British English, British also homoeostasis) Help:IPA/English, (/hɒmɪə(ʊ)ˈsteɪsɪs/) is the state of steady internal, physics, physical, and chemistry, chemical conditions maintained by organism, living systems. This is the condition of optimal functioning for the organism and includes many variables, such as body temperature and fluid balance, being kept within certain pre-set limits (homeostatic range). Other variables include the pH of extracellular fluid, the concentrations of sodium, potassium and calcium ions, as well as that of the blood sugar level, and these need to be regulated despite changes in the environment, diet, or level of activity. Each of these variables is controlled by one or more regulators or homeostatic mechanisms, which together maintain life. Homeostasis is brought about by a natural resistance to change when already in the optimal conditions, and equilibrium is maintained by many regulatory mechanisms: it is thought to be ...
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Neural Plasticity
Neuroplasticity, also known as neural plasticity, or brain plasticity, is the ability of neural networks in the brain to change through growth and reorganization. It is when the brain is rewired to function in some way that differs from how it previously functioned. These changes range from individual neuron pathways making new connections, to systematic adjustments like cortical remapping. Examples of neuroplasticity include circuit and network changes that result from learning a new ability, environmental influences, practice, and psychological stress. Neuroplasticity was once thought by neuroscientists to manifest only during childhood, but research in the latter half of the 20th century showed that many aspects of the brain can be altered (or are "plastic") even through adulthood. However, the developing brain exhibits a higher degree of plasticity than the adult brain. Activity-dependent plasticity can have significant implications for healthy development, learning, memory ...
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