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Ernest Kennaway
Sir Ernest Laurence Kennaway FRS (23 May 1881 – 1 January 1958) was a British pathologist and Royal Medal winner. He first became interested in natural life when, due to a childhood illness, he was encouraged to spend time outdoors. He was trained at University College London, and in 1898 was accepted into New College, Oxford on an open scholarship to study natural sciences. He graduated with a B.A. in 1903, and after three years at Middlesex Hospital he completed a Bachelor of Medicine and Surgery. After graduating he worked for The Lister Institute for Preventive Medicine and UCL before returning to Oxford, this time to Brasenose College on a Hulme scholarship in 1909. He became a Travelling Fellow of Brasenose in 1910, a Doctor of Medicine in 1911 and a Doctor of Science (specifically physiological chemistry) in 1915. In 1909 he became a physiology demonstrator at Guy's Hospital, where he remained until he was made head of the department of chemical pathology at the Bland-Sut ...
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Exeter
Exeter () is a city in Devon, South West England. It is situated on the River Exe, approximately northeast of Plymouth and southwest of Bristol. In Roman Britain, Exeter was established as the base of Legio II Augusta under the personal command of Vespasian. Exeter became a religious centre in the Middle Ages. Exeter Cathedral, founded in the mid 11th century, became Anglican in the 16th-century English Reformation. Exeter became an affluent centre for the wool trade, although by the First World War the city was in decline. After the Second World War, much of the city centre was rebuilt and is now a centre for education, business and tourism in Devon and Cornwall. It is home to two of the constituent campuses of the University of Exeter: Streatham and St Luke's. The administrative area of Exeter has the status of a non-metropolitan district under the administration of the County Council. It is the county town of Devon and home to the headquarters of Devon County Council. A p ...
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Doctor Of Science
Doctor of Science ( la, links=no, Scientiae Doctor), usually abbreviated Sc.D., D.Sc., S.D., or D.S., is an academic research degree awarded in a number of countries throughout the world. In some countries, "Doctor of Science" is the degree used for the standard doctorate in the sciences; elsewhere the Sc.D. is a "higher doctorate" awarded in recognition of a substantial and sustained contribution to scientific knowledge beyond that required for a Doctor of Philosophy (PhD). Africa Algeria and Morocco In Algeria, Morocco, Libya and Tunisia, all universities accredited by the state award a "Doctorate" in all fields of science and humanities, equivalent to a PhD in the United Kingdom or United States. Some universities in these four Arab countries award a "Doctorate of the State" in some fields of study and science. A "Doctorate of the State" is slightly higher in esteem than a regular doctorate, and is awarded after performing additional in-depth post-doctorate research or ach ...
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1958 Deaths
Events January * January 1 – The European Economic Community (EEC) comes into being. * January 3 – The West Indies Federation is formed. * January 4 ** Edmund Hillary's Commonwealth Trans-Antarctic Expedition completes the third overland journey to the South Pole, the first to use powered vehicles. ** Sputnik 1 (launched on October 4, 1957) falls to Earth from its orbit, and burns up. * January 13 – Battle of Edchera: The Moroccan Army of Liberation ambushes a Spanish patrol. * January 27 – A Soviet-American executive agreement on cultural, educational and scientific exchanges, also known as the " Lacy–Zarubin Agreement", is signed in Washington, D.C. * January 31 – The first successful American satellite, Explorer 1, is launched into orbit. February * February 1 – Egypt and Syria unite, to form the United Arab Republic. * February 6 – Seven Manchester United footballers are among the 21 people killed in the Munich air disaster in West G ...
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1881 Births
Events January–March * January 1– 24 – Siege of Geok Tepe: Russian troops under General Mikhail Skobelev defeat the Turkomans. * January 13 – War of the Pacific – Battle of San Juan and Chorrillos: The Chilean army defeats Peruvian forces. * January 15 – War of the Pacific – Battle of Miraflores: The Chileans take Lima, capital of Peru, after defeating its second line of defense in Miraflores. * January 24 – William Edward Forster, chief secretary for Ireland, introduces his Coercion Bill, which temporarily suspends habeas corpus so that those people suspected of committing an offence can be detained without trial; it goes through a long debate before it is accepted February 2. * January 25 – Thomas Edison and Alexander Graham Bell form the Oriental Telephone Company. * February 13 – The first issue of the feminist newspaper ''La Citoyenne'' is published by Hubertine Auclert. * February 16 – The Canad ...
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Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms become more common. The most obvious early symptoms are tremor, rigidity, slowness of movement, and difficulty with walking. Cognitive and behavioral problems may also occur with depression, anxiety, and apathy occurring in many people with PD. Parkinson's disease dementia becomes common in the advanced stages of the disease. Those with Parkinson's can also have problems with their sleep and sensory systems. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain, leading to a dopamine deficit. The cause of this cell death is poorly understood, but involves the build-up of misfolded proteins into Lewy bodies in the neurons. Collectively, the main motor symptoms are also known as ...
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Case–control Study
A case–control study (also known as case–referent study) is a type of observational study in which two existing groups differing in outcome are identified and compared on the basis of some supposed causal attribute. Case–control studies are often used to identify factors that may contribute to a medical condition by comparing subjects who have that condition/disease (the "cases") with patients who do not have the condition/disease but are otherwise similar (the "controls"). They require fewer resources but provide less evidence for causal inference than a randomized controlled trial. A case–control study produces only an odds ratio, which is an inferior measure of strength of association compared to relative risk. Definition The case–control is a type of epidemiological observational study. An observational study is a study in which subjects are not randomized to the exposed or unexposed groups, rather the subjects are ''observed'' in order to determine both their expos ...
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Medical Research Council (United Kingdom)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ...
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University Of London
The University of London (UoL; abbreviated as Lond or more rarely Londin in post-nominals) is a federal public research university located in London, England, United Kingdom. The university was established by royal charter in 1836 as a degree-awarding examination board for students holding certificates from University College London and King's College London and "other such other Institutions, corporate or unincorporated, as shall be established for the purpose of Education, whether within the Metropolis or elsewhere within our United Kingdom". This fact allows it to be one of three institutions to claim the title of the third-oldest university in England, and moved to a federal structure in 1900. It is now incorporated by its fourth (1863) royal charter and governed by the University of London Act 2018. It was the first university in the United Kingdom to introduce examinations for women in 1869 and, a decade later, the first to admit women to degrees. In 1913, it appointe ...
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Polycyclic Aromatic Hydrocarbon
A polycyclic aromatic hydrocarbon (PAH) is a class of organic compounds that is composed of multiple aromatic rings. The simplest representative is naphthalene, having two aromatic rings and the three-ring compounds anthracene and phenanthrene. PAHs are uncharged, non-polar and planar. Many are colorless. Many of them are found in coal and in oil deposits, and are also produced by the combustion of organic matter—for example, in engines and incinerators or when biomass burns in forest fires. Polycyclic aromatic hydrocarbons are discussed as possible starting materials for abiotic syntheses of materials required by the earliest forms of life. Nomenclature and structure The terms polyaromatic hydrocarbon or polynuclear aromatic hydrocarbon are also used for this concept. By definition, polycyclic aromatic hydrocarbons have multiple rings, precluding benzene from being considered a PAH. Some sources, such as the US EPA and CDC, consider naphthalene to be the simplest PAH. ...
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Izrael Hieger
Izrael Hieger DSc (London) (13 June 1901 – 14 October 1986) was a biochemist whose work focused on carcinogenesis. He discovered the first known organic carcinogenic compound. In 1937 Hieger, with colleagues Ernest Kennaway and J. W. Cook, was nominated for a Nobel Prize for work on isolating chemical carcinogenic agents from tar and studies on the relation between chemical constitution and carcinogenic activity. Early life Hieger was born in Siedlce, Russian Empire (present Republic of Poland), and was the youngest of nine. Preempting the pogrom of 1906, Heiger's parents emigrated with the younger children, settling in London. There he attended Christ's College, Finchley, going on to study at Birkbeck, University of London and University College London. Heiger married Esther (née Bull), and although not a member, financially assisted a Trotskyist group in London run by C.L.R. James, of which Esther and her future husband Earle Birney were a part. Their marriage ended in 193 ...
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Methylcholanthrene
Methylcholanthrene is a highly carcinogenic polycyclic aromatic hydrocarbon produced by burning organic compounds at very high temperatures. Methylcholanthrene is also known as 3-methylcholanthrene, 20-methylcholanthrene or the IUPAC name 3-methyl-1,2-dyhydrobenzo ceanthrylene. The short notation often used is 3-MC or MCA. This compound forms pale yellow solid crystals when crystallized from benzene and ether. It has a melting point around 180 °C and its boiling point is around 280 °C at a pressure of 80 mmHg. Methylcholanthrene is used in laboratory studies of chemical carcinogenesis. It is an alkylated derivative of benz 'a''nthracene and has a similar UV spectrum. The most common isomer is 3-methylcholanthrene, although the methyl group can occur in other places. 3-Methylcholanthrene, a known carcinogen which builds up in the prostate due to cholesterol breakdown, is implicated in prostate cancer. It "readily produces" primary sarcomas in mice. History In 19 ...
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Cyclic Hydrocarbon
A cyclic compound (or ring compound) is a term for a compound in the field of chemistry in which one or more series of atoms in the compound is connected to form a ring. Rings may vary in size from three to many atoms, and include examples where all the atoms are carbon (i.e., are carbocycles), none of the atoms are carbon (inorganic cyclic compounds), or where both carbon and non-carbon atoms are present (heterocyclic compounds). Depending on the ring size, the bond order of the individual links between ring atoms, and their arrangements within the rings, carbocyclic and heterocyclic compounds may be aromatic or non-aromatic; in the latter case, they may vary from being fully saturated to having varying numbers of multiple bonds between the ring atoms. Because of the tremendous diversity allowed, in combination, by the valences of common atoms and their ability to form rings, the number of possible cyclic structures, even of small size (e.g., < 17 total atoms) numbers in the many b ...
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