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Ergogenic Use Of Anabolic Steroids
Since their discovery, anabolic steroids (AAS) have been widely used as performance-enhancing drugs to improve performance in sports, to improve one's physical appearance, as self-medication to recover from injury, and as an anti-aging aid. Use of anabolic steroids for purposes other than treating medical conditions is controversial and, in some cases, illegal. Major sports organizations have moved to ban the use of anabolic steroids. There is a wide range of health concerns for users. Legislation in many countries restricts and criminalizes AAS possession and trade. History Performance-enhancing substances have been used for thousands of years in traditional medicine by societies around the world, with the aim of promoting vitality and strength. The use of gonadal hormones pre-dates their identification and isolation. Medical use of testicle extract began in the late 19th century, while its effects on strength were still being studied. In 1889, the 72-year-old Mauritian neurol ...
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Anabolic Steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone (medication), testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone. They increase protein within cell (biology), cells, especially in skeletal muscles, and also have varying degrees of virilization, virilizing effects, including induction of the development and maintenance of male, masculine secondary sexual characteristics such as the growth of facial hair, facial and body hair. The word ''anabolic'', referring to anabolism, comes from the Greek ἀναβολή ''anabole'', "that which is thrown up, mound". Androgens or AAS are one of three types of sex hormone agonists, the others being estrogen (medication), estrogens like estradiol (medication), estradiol and progestogens like progesterone (medication), progesterone. AAS were synthesized in the 1930s, and are ...
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Dianabol
Metandienone, also known as methandienone or methandrostenolone and sold under the brand name Dianabol (D-Bol) among others, is an androgen and anabolic steroid (AAS) medication which is still quite often used because of its affordability and effectiveness for bulking cycles. It is also used non-medically for physique- and performance-enhancing purposes. It is often taken by mouth. Side effects of metandienone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire, estrogenic effects like fluid retention and breast enlargement, and liver damage. The drug is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT), and has strong anabolic effects and moderate androgenic effects. It also has moderate estrogenic effects. Metandienone was originally developed in 1955 by CIBA and marketed in Germany and the United States. As the CIBA product Dianabol, ...
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Muscle Dysmorphia
Muscle dysmorphia is a subtype of the obsessive mental disorder body dysmorphic disorder, but is often also grouped with eating disorders.Lee F Monaghan & Michael Atkinson, ''Challenging Myths of Masculinity: Understanding Physical Cultures'' (Surrey: Ashgate, 2014)p 86 In muscle dysmorphia, which is sometimes called "bigorexia", "megarexia", or "reverse anorexia", the delusional or exaggerated belief is that one's own body is too small, too skinny, insufficiently muscular, or insufficiently lean, although in most cases, the individual's build is normal or even exceptionally large and muscular already.Katharine A Phillips, ''Understanding Body Dysmorphic Disorder: An Essential Guide'' (New York: Oxford University Press, 2009), p50–51James E Leone, Edward J Sedory & Kimberly A Gray"Recognition and treatment of muscle dysmorphia and related body image disorders" ''Journal of Athletic Training'', 2005 Oct–Dec;40(4):352–359. Muscle dysmorphia affects mostly men, particularly thos ...
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Addiction (journal)
''Addiction'' is a monthly peer-reviewed scientific journal established in 1903 by the Society for the Study of Addiction to Alcohol and other Drugs as the ''British Journal of Inebriety''. It was renamed ''British Journal of Addiction to Alcohol & Other Drugs'' in 1947, then renamed to ''British Journal of Addiction'' in 1980, before finally obtaining its current name in 1993. It covers research relating to the abuse of alcohol abuse, alcohol, substance abuse, illicit drugs, and tobacco abuse, tobacco, as well as behavioural addictions. The editor-in-chief is John Marsden (scientist), John Marsden (King's College London). Article types The journal publishes research reports, reviews, commentaries, and letters to the editor relating to all aspects of addictive behaviours. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2019 impact factor of 6.340. References External links

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12th Grade
Twelfth grade, 12th grade, senior year, or grade 12 is the final year of secondary school in most of North America. In other regions, it may also be referred to as class 12 or Year 13. In most countries, students are usually between the ages of 17 and 18 years old. Some countries have a thirteenth grade, while other countries do not have a 12th grade/year at all. Twelfth grade is typically the last year of high school (graduation year). Australia In Australia, the twelfth grade is referred to as Year 12. In New South Wales, students are usually 16 or 17 years old when they enter Year 12 and 17 or 18 years during graduation (end of year). A majority of students in Year 12 work toward getting an ATAR (Australian Tertiary Admission Rank). Up until the start of 2020 the OP (Overall Position, which applies only to students in the state of Queensland) was used. Both of these allow/allowed them access to courses at university. In Western Australia, this is achieved by completing the WACE ...
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Middle School
A middle school (also known as intermediate school, junior high school, junior secondary school, or lower secondary school) is an educational stage which exists in some countries, providing education between primary school and secondary school. The concept, regulation and classification of middle schools, as well as the ages covered, vary between and sometimes within countries. Afghanistan In Afghanistan, middle school includes grades 6, 7, and 8, consisting of students from ages 11 to 14. Algeria In Algeria, a middle school includes 4 grades: 6, 7, 8, and 9, consisting of students from ages 11–15. Argentina The of secondary education (ages 11–14) is roughly equivalent to middle school. Australia No regions of Australia have segregated middle schools, as students go directly from primary school (for years K/preparatory–6) to secondary school (years 7–12, usually referred to as high school). As an alternative to the middle school model, some secondary schools classi ...
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Median
In statistics and probability theory, the median is the value separating the higher half from the lower half of a data sample, a population, or a probability distribution. For a data set, it may be thought of as "the middle" value. The basic feature of the median in describing data compared to the mean (often simply described as the "average") is that it is not skewed by a small proportion of extremely large or small values, and therefore provides a better representation of a "typical" value. Median income, for example, may be a better way to suggest what a "typical" income is, because income distribution can be very skewed. The median is of central importance in robust statistics, as it is the most resistant statistic, having a breakdown point of 50%: so long as no more than half the data are contaminated, the median is not an arbitrarily large or small result. Finite data set of numbers The median of a finite list of numbers is the "middle" number, when those numbers are list ...
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Heterosexual
Heterosexuality is romantic attraction, sexual attraction or sexual behavior between people of the opposite sex or gender. As a sexual orientation, heterosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions" to people of the opposite sex; it "also refers to a person's sense of identity based on those attractions, related behaviors, and membership in a community of others who share those attractions." Someone who is heterosexual is commonly referred to as ''straight.'' Along with bisexuality and homosexuality, heterosexuality is one of the three main categories of sexual orientation within the heterosexual–homosexual continuum. Across cultures, most people are heterosexual, and heterosexual activity is by far the most common type of sexual activity. Scientists do not know the exact cause of sexual orientation, but they theorize that it is caused by a complex interplay of genetic, hormonal, and environmental influences, and do not view it as ...
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NCAA
The National Collegiate Athletic Association (NCAA) is a nonprofit organization that regulates student athletics among about 1,100 schools in the United States, Canada, and Puerto Rico. It also organizes the athletic programs of colleges and universities in the United States and Canada and helps over 500,000 college student athletes who compete annually in college sports. The organization is headquartered in Indianapolis, Indiana. Until 1957, the NCAA was a single division for all schools. That year, the NCAA split into the University Division and the College Division. In August 1973, the current three-division system of Division I, Division II, and Division III was adopted by the NCAA membership in a special convention. Under NCAA rules, Division I and Division II schools can offer scholarships to athletes for playing a sport. Division III schools may not offer any athletic scholarships. Generally, larger schools compete in Division I and smaller schools in II and III. ...
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Double Blind
In a blind or blinded experiment, information which may influence the participants of the experiment is withheld until after the experiment is complete. Good blinding can reduce or eliminate experimental biases that arise from a participants' expectations, observer's effect on the participants, observer bias, confirmation bias, and other sources. A blind can be imposed on any participant of an experiment, including subjects, researchers, technicians, data analysts, and evaluators. In some cases, while blinding would be useful, it is impossible or unethical. For example, it is not possible to blind a patient to their treatment in a physical therapy intervention. A good clinical protocol ensures that blinding is as effective as possible within ethical and practical constraints. During the course of an experiment, a participant becomes unblinded if they deduce or otherwise obtain information that has been masked to them. For example, a patient who experiences a side effect may correc ...
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Oregon State University
Oregon State University (OSU) is a public land-grant, research university in Corvallis, Oregon. OSU offers more than 200 undergraduate-degree programs along with a variety of graduate and doctoral degrees. It has the 10th largest engineering college in the nation for 2022. Undergraduate enrollment for all colleges combined averages close to 32,000, making it the state's largest university. Out-of-state students make up over one-quarter of undergraduates and an additional 5,500 students are engaged in graduate coursework through the university. Since its founding, over 272,000 students have graduated from OSU. It is classified among "Doctoral Universities – Very high research activity". Chartered as a land-grant university initially, OSU became one of the four inaugural members of the Sea Grant in 1971. It joined the Space Grant and Sun Grant research consortia in 1991 and 2003, respectively, making it the first public university and one of just four in total to attain memb ...
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Open Label
An open-label trial, or open trial, is a type of clinical trial in which information is not withheld from trial participants. In particular, both the researchers and participants know which treatment is being administered. This contrasts with a blinded experiment, double-blinded trial, where information is withheld both from the researchers and the participants to reduce bias. Open-label trials may be appropriate for comparing two similar treatments to determine which is most effective, such as a comparison of different prescription drug, prescription anticoagulants, or possible relief from symptoms of some disorders when a placebo is given. An open-label trial may still be randomized controlled trial, randomized. Open-label trials may also be uncontrolled (without a placebo-controlled study, placebo group), with all participants receiving the same treatment. References

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