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E45 Cream
E45 cream is a skin care product created in 1952 and currently marketed by Karo Pharma. It contains the following active ingredients: lanolin, white soft paraffin and liquid paraffin. Although it was initially only available in hospitals, increased demand and successful results made the product available at retail as well. After belonging to a subsidiary of the Reckitt group until mid-year, the brand was sold on April 1, 2022 and ownership was transferred by Crookes Healthcare to Karo Pharma. E45 cream E45 is an emollient. Emollients are proven to seal in moisture. Paraffin creates a breathable and hypoallergenic layer over damaged skin to protect it from potential irritants whilst lanolin heals and softens the epidermis. The effectiveness of E45 doubles when applied on skin that is still slightly damp. In 2016 it was one of the biggest selling branded over-the-counter medications sold in Great Britain, with sales of £35.5 million. The product contains paraffin (a fire ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skin Care Product
Cosmetics are constituted mixtures of chemical compounds derived from either Natural product, natural sources, or synthetically created ones. Cosmetics have various purposes. Those designed for personal care and skin care can be used to Cleaning, cleanse or protect the body or skin. Cosmetics designed to enhance or alter one's appearance (makeup) can be used to conceal blemishes, enhance one's natural features (such as the eyebrows and eyelashes), add color to a person's face, or change the appearance of the face entirely to resemble a different person, creature or object. Cosmetics can also be designed to add fragrance to the body. Definition and etymology The word ''cosmetics'' derives from the Ancient Greek, Greek (), meaning "technique of dress and ornament", from (), "skilled in ordering or arranging" and that from (), meaning "order" and "ornament". Cosmetics are constituted from a mixture of chemical compound A chemical compound is a chemical substance com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Over-the-counter
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription. In many countries, OTC drugs are selected by a regulatory agency to ensure that they contain ingredients that are safe and effective when used without a physician's care. OTC drugs are usually regulated according to their active pharmaceutical ingredient (API) rather than final products. By regulating APIs instead of specific drug formulations, governments allow manufacturers the freedom to formulate ingredients, or combinations of ingredients, into proprietary mixtures. The term ''over-the-counter'' (''OTC'') refers to a medication that can be purchased without a medical prescription. In contrast, prescription drugs require a prescription from a doctor or other health care professional and should only be used by the prescribe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycerol Monostearate
Glycerol monostearate, commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods. It takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic. Chemically it is the glycerol ester of stearic acid It is also used as hydration powder in exercise formulas Structure, synthesis, and occurrence Glycerol monostearate exists as three stereoisomers, the enantiomeric pair of 1-glycerol monostearate and 2-glycerol monostearate. Typically these are encountered as a mixture as many of their properties are similar. Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol. Glycerol monostearate occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase. It is present at very low levels in certain seed oils. Uses GMS is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Liquid Paraffin (drug)
Liquid paraffin, also known as ''paraffinum liquidum'', paraffin oil, liquid paraffin oil or Russian mineral oil, is a very highly refined mineral oil used in cosmetics and medicine. Cosmetic or medicinal liquid paraffin should not be confused with the paraffin (i.e. kerosene) used as a fuel. The generic sense of paraffin meaning alkane led to regional differences for the meanings of both ''paraffin'' and ''paraffin oil''. It is a transparent, colorless, nearly odorless, and oily liquid that is composed of saturated hydrocarbons derived from petroleum. The term ''paraffinum perliquidum'' is sometimes used to denote light liquid paraffin, while the term ''paraffinum subliquidum'' is sometimes used to denote a thicker mineral oil. History Petroleum is said to have been used as a medicine since 400 BC, and has been mentioned in the texts of classical writers Herodotus, Plutarch, Dioscorides, Pliny, and others. It was used extensively by early Arabians and was important in early ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paraffin Wax
Paraffin wax (or petroleum wax) is a soft colorless solid derived from petroleum, coal, or oil shale that consists of a mixture of hydrocarbon molecules containing between 20 and 40 carbon atoms. It is solid at room temperature and begins to melt above approximately , and its boiling point is above . Common applications for paraffin wax include lubrication, electrical insulation, and candles; dyed paraffin wax can be made into crayons. It is distinct from kerosene and other petroleum products that are sometimes called paraffin. Un-dyed, unscented paraffin candles are odorless and bluish-white. Paraffin wax was first created by Carl Reichenbach in Germany in 1830 and marked a major advancement in candlemaking technology, as it burned more cleanly and reliably than tallow candles and was cheaper to produce. In chemistry, ''paraffin'' is used synonymously with ''alkane'', indicating hydrocarbons with the general formula C''n''H2''n''+2. The name is derived from Latin ''parum'' (" ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lanolin
Lanolin (from Latin 'wool', and 'oil'), also called wool yolk, wool wax, or wool grease, is a wax secreted by the sebaceous glands of wool-bearing animals. Lanolin used by humans comes from domestic sheep breeds that are raised specifically for their wool. Historically, many pharmacopoeias have referred to lanolin as wool fat (''adeps lanae''); however, as lanolin lacks glycerides (glycerol esters), it is not a true fat. Lanolin primarily consists of sterol esters instead. Lanolin's waterproofing property aids sheep in shedding water from their coats. Certain breeds of sheep produce large amounts of lanolin. Lanolin's role in nature is to protect wool and skin from climate and the environment; it also plays a role in skin ( integumental) hygiene. Lanolin and its derivatives are used in the protection, treatment, and beautification of human skin. Composition A typical high-purity grade of lanolin is composed predominantly of long chain waxy esters (approximately 97% by weight) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fire
Fire is the rapid oxidation of a material (the fuel) in the exothermic chemical process of combustion, releasing heat, light, and various reaction Product (chemistry), products. At a certain point in the combustion reaction, called the ignition point, flames are produced. The ''flame'' is the visible portion of the fire. Flames consist primarily of carbon dioxide, water vapor, oxygen and nitrogen. If hot enough, the gases may become ionized to produce Plasma (physics), plasma. Depending on the substances alight, and any impurities outside, the color of the flame and the fire's Intensity (heat transfer), intensity will be different. Fire in its most common form can result in conflagration, which has the potential to cause physical damage through burning. Fire is an important process that affects ecological systems around the globe. The positive effects of fire include stimulating growth and maintaining various ecological systems. Its negative effects include hazard to life and pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fire Accelerant
In fire protection, an accelerant is any substance or mixture that accelerates or speeds the development and escalation of fire. Accelerants are often used to commit arson, and some accelerants may cause an explosion. Some fire investigators use the term "accelerant" to mean any substance that initiates and promotes a fire without implying intent or malice. A fire is a self-sustaining, exothermic reaction, exothermic oxidation reaction that emits heat and light. When a fire is accelerated, it can produce more heat, consume the reactants more quickly, burn at a higher temperature, and increase the spread of the fire. An accelerated fire is said to have a higher "heat release rate," meaning it burns more quickly. Fire investigation Indicators of an incendiary fire or arson can lead fire investigators to look for the presence of accelerants in fire debris. Accelerants can leave behind evidence of their presence and use. Accelerants present in areas they should not be can indicate an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidermis
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. The epidermis layer provides a barrier to infection from environmental pathogens and regulates the amount of water released from the body into the atmosphere through transepidermal water loss. The epidermis is composed of multiple layers of flattened cells that overlie a base layer (stratum basale) composed of columnar cells arranged perpendicularly. The layers of cells develop from stem cells in the basal layer. The human epidermis is a familiar example of epithelium, particularly a stratified squamous epithelium. The word epidermis is derived through Latin , itself and . Something related to or part of the epidermis is termed epidermal. Structure Cellular components The epidermis primarily consists of keratinocytes ( proliferating basal and differentiated suprabasal), which comprise 90% of its cells, but also contains melanocytes, Langerhans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karo Pharma
Karo may refer to: Ethnic groups * Karo people (East Africa), a group of tribes in East Africa * Karo people (Ethiopia), an ethnic group from Ethiopia * Karo people (Indonesia), the indigenous people of the Karo Plateau in North Sumatra Languages * Karo language (Brazil), a Tupian language * Karo language (Ethiopia), an Omotic language * Karo language (Nilotic), a Nilotic language of Uganda, South Sudan and the DRC * Karo language (Indonesia), an Austronesian language spoken in Sumatra, Indonesia * The Kalo dialect of the Austronesian Keapara language of Papua New Guinea * The Karo dialect of the Papuan Rawa language of Papua New Guinea People * Karo (name), a list of people with the given name or surname Other uses * Karo Regency, a regency of North Sumatra, Indonesia * KARO (98.7 FM) a radio station of Oregon, the United States * Karō, samurai officials and advisers of feudal Japan * Karo-kari (honor killings against men is Karo) *Karo syrup, a US brand of corn syrup * Kar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Moisturizer
A moisturizer, or emollient, is a cosmetic preparation used for protecting, moisturizing, and lubricating the skin. These functions are normally performed by sebum produced by healthy skin. The word "emollient" is derived from the Latin verb ''mollire'', to soften. Mechanism of action In the human body, water constantly evaporates from the deeper layers of the skin through an effect known as transepidermal water loss (TEWL). By regulating its water content, human skin naturally maintains a dry, easily shed surface as a barrier against pathogens, dirt, or damage, while protecting itself from drying out and becoming brittle and rigid. The ability to retain moisture depends on the lipid bilayer between the corneocytes. Moisturizers modify the rate of water loss, with active ingredients of moisturizers falling into one of two categories: occlusives and humectants. Occlusives form a coating on the surface of the skin, keeping moisture from escaping. The more occlusive the formula ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crookes Healthcare
Crookes Healthcare is a healthcare manufacturer based in Nottingham, UK and a subsidiary of Reckitt. It manufactures some of the most well-known health remedies and over-the-counter medicines (OTC) found in British chemists. History The name comes from Sir William Crookes, a chemist. Crookes Collosols, started by Henry Crookes, the son of William Crookes, was formed on 29 March 1912. British Colloids Ltd, formed in December 1918, bought this company in January 1919. In 1946, it became The Crookes Laboratories Ltd, on ''Gorst Road'' in north-west London. It became a public company on 28 February 1951. Crookes Laboratories was an international company. One of its best-selling products was the LactoCalamine skin-care range. This latter featured the Hollywood film star Audrey Hepburn in its adverts. By the 1960s it was making dosulepin, a tricyclic antidepressant (TCA), under the brand name ''Prothiaden''. Ownership Guinness In November 1960 it was bought by Arthur Guinness Son ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
