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Donald C. Chang
Donald Choy Chang (; 1942) is a founding professor of the Hong Kong University of Science and Technology (HKUST). He was also the founding ''President'' of the Biophysical Society of Hong Kong. He is currently Professor Emeritus and Adjunct Professor in HKUST, and ''Council Member'' of Hong Kong Institute of Science (HKIS). Chang has wide research interest: He was an experimental physicist by training; but his publication ranges from nuclear magnetic resonance, biophysics and quantum physics. Detection of cancer using nuclear magnetic resonance (NMR) Chang is an early pioneer in the study of the physical properties of water in cells using spin-echo nuclear magnetic resonance (NMR) techniques. When Donald Chang was working in the Physics Department at Rice University, he built a home-made NMR spectrometer to measure the relaxation times (T1 and T2) of water in normal cells/tissues, cancer cells and simply in free water samples. His major collaborator at that time was the physiol ...
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Electroporation
Electroporation, or electropermeabilization, is a microbiology technique in which an electrical field is applied to cells in order to increase the permeability of the cell membrane, allowing chemicals, drugs, electrode arrays or DNA to be introduced into the cell (also called electrotransfer). In microbiology, the process of electroporation is often used to transform bacteria, yeast, or plant protoplasts by introducing new coding DNA. If bacteria and plasmids are mixed together, the plasmids can be transferred into the bacteria after electroporation, though depending on what is being transferred, cell-penetrating peptides or CellSqueeze could also be used. Electroporation works by passing thousands of volts (~8 kV/cm) across suspended cells in an electroporation cuvette. Afterwards, the cells have to be handled carefully until they have had a chance to divide, producing new cells that contain reproduced plasmids. This process is approximately ten times more effective in increasing ...
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Förster Resonance Energy Transfer
Förster resonance energy transfer (FRET), fluorescence resonance energy transfer, resonance energy transfer (RET) or electronic energy transfer (EET) is a mechanism describing energy transfer between two light-sensitive molecules ( chromophores). A donor chromophore, initially in its electronic excited state, may transfer energy to an acceptor chromophore through nonradiative dipole–dipole coupling. The efficiency of this energy transfer is inversely proportional to the sixth power of the distance between donor and acceptor, making FRET extremely sensitive to small changes in distance. Measurements of FRET efficiency can be used to determine if two fluorophores are within a certain distance of each other. Such measurements are used as a research tool in fields including biology and chemistry. FRET is analogous to near-field communication, in that the radius of interaction is much smaller than the wavelength of light emitted. In the near-field region, the excited chromophore e ...
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Hong Kong People
Hongkongers (), also known as Hong Kongers, Hong Kongese, Hongkongese, Hong Kong citizens and Hong Kong people, typically refers to residents of the territory of Hong Kong; although may also refer to others who were born and/or raised in the territory. The earliest inhabitants of Hong Kong are indigenous villagers, who have lived in the area since before British colonization. The majority of Hongkongers today are descended from Han Chinese migrants from mainland China, most of whom are Cantonese and trace their ancestral home to the province of Guangdong. However, the territory also holds other Han Chinese subgroups including the Hakka, Hoklo, Teochew (Chiuchow), Shanghainese, Sichuanese and Taiwanese. Meanwhile, non-Han Chinese Hongkongers such as the British, Filipinos, Indonesians, South Asians and Vietnamese also make up six per cent of Hong Kong's population. Terminology The terms ''Hongkonger'' and ''Hong Kongese'' are used to denote a residents of Hong Kong, includi ...
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1942 Births
Year 194 ( CXCIV) was a common year starting on Tuesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Septimius and Septimius (or, less frequently, year 947 ''Ab urbe condita''). The denomination 194 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus and Decimus Clodius Septimius Albinus Caesar become Roman Consuls. * Battle of Issus: Septimius Severus marches with his army (12 legions) to Cilicia, and defeats Pescennius Niger, Roman governor of Syria. Pescennius retreats to Antioch, and is executed by Severus' troops. * Septimius Severus besieges Byzantium (194–196); the city walls suffer extensive damage. Asia * Battle of Yan Province: Warlords Cao Cao and Lü Bu fight for control over Yan Province; the battle lasts for over 100 ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Digital Object Identifier
A digital object identifier (DOI) is a persistent identifier or handle used to uniquely identify various objects, standardized by the International Organization for Standardization (ISO). DOIs are an implementation of the Handle System; they also fit within the URI system ( Uniform Resource Identifier). They are widely used to identify academic, professional, and government information, such as journal articles, research reports, data sets, and official publications. DOIs have also been used to identify other types of information resources, such as commercial videos. A DOI aims to resolve to its target, the information object to which the DOI refers. This is achieved by binding the DOI to metadata about the object, such as a URL where the object is located. Thus, by being actionable and interoperable, a DOI differs from ISBNs or ISRCs which are identifiers only. The DOI system uses the indecs Content Model for representing metadata. The DOI for a document remains fixed over t ...
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OCLC
OCLC, Inc., doing business as OCLC, See also: is an American nonprofit cooperative organization "that provides shared technology services, original research, and community programs for its membership and the library community at large". It was founded in 1967 as the Ohio College Library Center, then became the Online Computer Library Center as it expanded. In 2017, the name was formally changed to OCLC, Inc. OCLC and thousands of its member libraries cooperatively produce and maintain WorldCat, the largest online public access catalog (OPAC) in the world. OCLC is funded mainly by the fees that libraries pay (around $217.8 million annually in total ) for the many different services it offers. OCLC also maintains the Dewey Decimal Classification system. History OCLC began in 1967, as the Ohio College Library Center, through a collaboration of university presidents, vice presidents, and library directors who wanted to create a cooperative, computerized network for libraries ...
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Michelson–Morley Experiment
The Michelson–Morley experiment was an attempt to detect the existence of the luminiferous aether, a supposed medium permeating space that was thought to be the carrier of light waves. The experiment was performed between April and July 1887 by American physicists Albert A. Michelson and Edward W. Morley at what is now Case Western Reserve University in Cleveland, Ohio, and published in November of the same year. The experiment compared the speed of light in perpendicular directions in an attempt to detect the relative motion of matter through the stationary luminiferous aether ("aether wind"). The result was negative, in that Michelson and Morley found no significant difference between the speed of light in the direction of movement through the presumed aether, and the speed at right angles. This result is generally considered to be the first strong evidence against the then-prevalent aether theory, as well as initiating a line of research that eventually led to special r ...
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Vacuum
A vacuum is a space devoid of matter. The word is derived from the Latin adjective ''vacuus'' for "vacant" or "void". An approximation to such vacuum is a region with a gaseous pressure much less than atmospheric pressure. Physicists often discuss ideal test results that would occur in a ''perfect'' vacuum, which they sometimes simply call "vacuum" or free space, and use the term partial vacuum to refer to an actual imperfect vacuum as one might have in a laboratory or in space. In engineering and applied physics on the other hand, vacuum refers to any space in which the pressure is considerably lower than atmospheric pressure. The Latin term ''in vacuo'' is used to describe an object that is surrounded by a vacuum. The ''quality'' of a partial vacuum refers to how closely it approaches a perfect vacuum. Other things equal, lower gas pressure means higher-quality vacuum. For example, a typical vacuum cleaner produces enough suction to reduce air pressure by around 20%. But hig ...
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Maxwell's Equations
Maxwell's equations, or Maxwell–Heaviside equations, are a set of coupled partial differential equations that, together with the Lorentz force law, form the foundation of classical electromagnetism, classical optics, and electric circuits. The equations provide a mathematical model for electric, optical, and radio technologies, such as power generation, electric motors, wireless communication, lenses, radar etc. They describe how electric and magnetic fields are generated by charges, currents, and changes of the fields.''Electric'' and ''magnetic'' fields, according to the theory of relativity, are the components of a single electromagnetic field. The equations are named after the physicist and mathematician James Clerk Maxwell, who, in 1861 and 1862, published an early form of the equations that included the Lorentz force law. Maxwell first used the equations to propose that light is an electromagnetic phenomenon. The modern form of the equations in their most common formul ...
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Planck's Law
In physics, Planck's law describes the spectral density of electromagnetic radiation emitted by a black body in thermal equilibrium at a given temperature , when there is no net flow of matter or energy between the body and its environment. At the end of the 19th century, physicists were unable to explain why the observed spectrum of black-body radiation, which by then had been accurately measured, diverged significantly at higher frequencies from that predicted by existing theories. In 1900, German physicist Max Planck heuristically derived a formula for the observed spectrum by assuming that a hypothetical electrically charged oscillator in a cavity that contained black-body radiation could only change its energy in a minimal increment, , that was proportional to the frequency of its associated electromagnetic wave. This resolved the problem of the ultraviolet catastrophe predicted by classical physics. This discovery was a pioneering insight of modern physics and is of fundam ...
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Planck Constant
The Planck constant, or Planck's constant, is a fundamental physical constant of foundational importance in quantum mechanics. The constant gives the relationship between the energy of a photon and its frequency, and by the mass-energy equivalence, the relationship between mass and frequency. Specifically, a photon's energy is equal to its frequency multiplied by the Planck constant. The constant is generally denoted by h. The reduced Planck constant, or Dirac constant, equal to the constant divided by 2 \pi, is denoted by \hbar. In metrology it is used, together with other constants, to define the kilogram, the SI unit of mass. The SI units are defined in such a way that, when the Planck constant is expressed in SI units, it has the exact value The constant was first postulated by Max Planck in 1900 as part of a solution to the ultraviolet catastrophe. At the end of the 19th century, accurate measurements of the spectrum of black body radiation existed, but the distribut ...
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