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Diseases And Epidemics Of The 19th Century
Diseases and epidemics of the 19th century included long-standing epidemic threats such as smallpox, typhus, yellow fever, and scarlet fever. In addition, cholera emerged as an epidemic threat and spread worldwide in six pandemics in the nineteenth century. The third plague pandemic emerged in China in the mid-nineteenth century and spread worldwide in the 1890s. Medical responses Medicine in the 19th century Epidemics of the 19th century were faced without the medical advances that made 20th-century epidemics much rarer and less lethal. Micro-organisms (viruses and bacteria) had been discovered in the 18th century, but it was not until the late 19th century that the experiments of Lazzaro Spallanzani and Louis Pasteur disproved spontaneous generation conclusively, allowing germ theory and Robert Koch's discovery of micro-organisms as the cause of disease transmission. Thus throughout the majority of the 19th century, there was only the most basic, common-sense understa ...
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The Cow Pock
''The'' () is a grammatical article in English, denoting persons or things that are already or about to be mentioned, under discussion, implied or otherwise presumed familiar to listeners, readers, or speakers. It is the definite article in English. ''The'' is the most frequently used word in the English language; studies and analyses of texts have found it to account for seven percent of all printed English-language words. It is derived from gendered articles in Old English which combined in Middle English and now has a single form used with nouns of any gender. The word can be used with both singular and plural nouns, and with a noun that starts with any letter. This is different from many other languages, which have different forms of the definite article for different genders or numbers. Pronunciation In most dialects, "the" is pronounced as (with the voiced dental fricative followed by a schwa) when followed by a consonant sound, and as (homophone of the archaic pr ...
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Chloroform
Chloroform, or trichloromethane, is an organic compound with chemical formula, formula Carbon, CHydrogen, HChlorine, Cl3 and a common organic solvent. It is a colorless, strong-smelling, dense liquid produced on a large scale as a precursor to PTFE. It is also a precursor to various refrigerants. It is trihalomethane. It is a powerful anesthetic, euphoriant, anxiolytic, and sedative when inhaled or ingested. Structure The molecule adopts a tetrahedral molecular geometry with C3v symmetry group, symmetry. Natural occurrence The total global flux of chloroform through the environment is approximately tonnes per year, and about 90% of emissions are natural in origin. Many kinds of seaweed produce chloroform, and fungi are believed to produce chloroform in soil. Abiotic processes are also believed to contribute to natural chloroform productions in soils although the mechanism is still unclear. Chloroform volatilizes readily from soil and surface water and undergoes degradation in ...
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Timeline Of Antibiotics
This is the timeline of modern antimicrobial (anti-infective) therapy. The years show when a given drug was released onto the pharmaceutical market. This is not a timeline of the development of the antibiotics themselves. * 1911 – Arsphenamine a.k.a. Salvarsan * 1912 – Neosalvarsan * 1935 – Prontosil (an oral precursor to sulfanilamide), the first sulfonamide * 1936 – Sulfanilamide * 1938 – Sulfapyridine (M&B 693) * 1939 – sulfacetamide * 1940 – sulfamethizole * 1942 – benzylpenicillin, the first penicillin * 1942 – gramicidin S, the first peptide antibiotic * 1942 – sulfadimidine * 1943 – sulfamerazine * 1944 – streptomycin, the first aminoglycoside * 1947 – sulfadiazine * 1948 – chlortetracycline, the first tetracycline * 1949 – chloramphenicol, the first amphenicol * 1949 – neomycin * 1950 – oxytetracycline * 1950 – penicillin G procaine * 1952 – erythromycin, the first macrolide * 1954 – benzathine penicillin * 1955 – spiramycin * ...
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Sulfonamide
In organic chemistry, the sulfonamide functional group (also spelled sulphonamide) is an organosulfur group with the structure . It consists of a sulfonyl group () connected to an amine group (). Relatively speaking this group is unreactive. Because of the rigidity of the functional group, sulfonamides are typically crystalline; for this reason, the formation of a sulfonamide is a classic method to convert an amine into a crystalline derivative which can be identified by its melting point. Many important drugs contain the sulfonamide group. A sulfonamide (compound) is a chemical compound that contains this group. The general formula is or , where each R is some organic group; for example, "methanesulfonamide" (where R = methane, R' = R" = hydrogen) is . Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group () with an amine group. In medicine, the term "sulfonamide" is sometimes used as a synonym for sulfa drug, a derivative or var ...
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Antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antiseptics) ...
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Waldemar Haffkine
Waldemar Mordechai Wolff Haffkine ( uk, Володимир Мордехай-Вольф Хавкін; russian: Мордехай-Вольф Хавкин; 15 March 1860 Odessa – 26 October 1930 Lausanne) was a Ukrainian-French bacteriologist known for his pioneering work in vaccines. Born into a Jewish family in Odessa, Russian Empire, Haffkin was educated at the University of Odessa and later emigrated first to Switzerland, then to France, working at the Pasteur Institute in Paris, where he developed a cholera vaccine that he tried out successfully in India. He is recognized as the first microbiologist who developed and used vaccines against cholera and bubonic plague. He tested the vaccines on himself. Lord Joseph Lister named him "a saviour of humanity". He was appointed Companion of the Order of the Indian Empire (CIE) in Queen Victoria's 1897 Diamond Jubilee Honours. The ''Jewish Chronicle'' of that time noted "a Ukraine Jew, trained in the schools of European science, save ...
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Jaume Ferran I Clua
''Jaime Ferrán y Clúa'' (Corbera d'Ebre, 1851 – Barcelona 1929) was a Spanish- French bacteriologist and sanitarian , contemporary of Robert Koch, and said by his fellows to have made some of the discoveries attributed to Koch. As early as 1885, he wrote on immunization against cholera. In 1893, his work on this subject was translated into French with the title ''L'Inoculation préventive contre le Cholera''. Tuberculosis is another disease in which Ferran was always deeply interested. Some of his ideas on the transmission and virulence of tuberculosis are revolutionary. He died in 1929 and was buried in Montjuïc Cemetery, Barcelona Barcelona ( , , ) is a city on the coast of northeastern Spain. It is the capital and largest city of the autonomous community of Catalonia, as well as the second most populous municipality of Spain. With a population of 1.6 million within ci .... Bibliography * U. TRUJILLANO, ''Ferrán, su obra sanitaria'', Madrid 1945; * G. M ...
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Filippo Pacini
Filippo Pacini (25 May 1812 – 9 July 1883) was an Italian anatomist, posthumously famous for isolating the cholera bacterium ''Vibrio cholerae'' in 1854, well before Robert Koch's more widely accepted discoveries 30 years later. Pacini was born in Pistoia, Tuscany, to Francesco, a humble cobbler, and Umiltà Dolfi, but was given a religious education in hopes that he would become a bishop. However, in 1830, he was given a scholarship to the most venerable medical school in Pistoia. He learned his job as a doctor and how to examine and dissect dead bodies under a microscope. In 1831, during a dissection class, Pacini discovered small sensory organs in the nervous system which can detect pressure and vibrations. He studied them closely from 1833 on, and first discussed them in 1835 at the ''Società medico-fisica'' in Florence, but did not publish his research ("''Nuovi organi scoperti nel corpo umano''") until 1840. Within just a few years, the work was widely known in Europe ...
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Baxby, Derrick
Derrick Baxby (1940 – 24 March 2017) was a British microbiologist and authority on ''Orthopoxviruses''. He was a senior lecturer in medical microbiology at the University of Liverpool. He proposed that a presumed horsepox virus could be the long-sought ancestor of vaccinia. In 1977, he reported 12 cases of cowpox occurring in England between 1965 and 1976. Selected publications * ''Jenner's Smallpox Vaccine: The Riddle of Vaccinia Virus and Its Origin''. Heinemann Educational Books, London, 1981. "Two hundred years of vaccination" ''Current Biology'', Vol. 6 (1996), No. 7, pp. 769–772. * "The End of Smallpox", ''History Today'', Vol. 49, No. 3 (March 1999). * "Edward Jenner's Inquiry; A Bicentenary Analysis", ''Vaccine A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verifie ...'' ...
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Vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or Antigen, killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic vaccines, therapeutic (to fight a disease that has already occurred, such as cancer vaccine, cancer).
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Medical Literature
Medical literature is the scientific literature of medicine: articles in journals and texts in books devoted to the field of medicine. Many references to the medical literature include the health care literature generally, including that of dentistry, veterinary medicine, pharmacy, nursing, and the allied health professions. Contemporary and historic views regarding diagnosis, prognosis and treatment of medical conditions have been documented for thousands of years. The Edwin Smith papyrus is the first known medical treatise. Ancient medical literature often described inflictions related to warfare. History Throughout history people have written about diseases, how human beings might contract them and what could be done to remedy it. Medicine ranged from folklore, witchcraft to the current evidence-based medicine. Among the most notable descriptions are texts from Egypt (Imhotep, ''Edwin Smith Papyrus'', '' Ebers Papyrus'', ''Kahun Gynecological Papyrus''), Mesopotamia ('' D ...
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Thomas Latta
Thomas may refer to: People * List of people with given name Thomas * Thomas (name) * Thomas (surname) * Saint Thomas (other) * Thomas Aquinas (1225–1274) Italian Dominican friar, philosopher, and Doctor of the Church * Thomas the Apostle * Thomas (bishop of the East Angles) (fl. 640s–650s), medieval Bishop of the East Angles * Thomas (Archdeacon of Barnstaple) (fl. 1203), Archdeacon of Barnstaple * Thomas, Count of Perche (1195–1217), Count of Perche * Thomas (bishop of Finland) (1248), first known Bishop of Finland * Thomas, Earl of Mar (1330–1377), 14th-century Earl, Aberdeen, Scotland Geography Places in the United States * Thomas, Illinois * Thomas, Indiana * Thomas, Oklahoma * Thomas, Oregon * Thomas, South Dakota * Thomas, Virginia * Thomas, Washington * Thomas, West Virginia * Thomas County (other) * Thomas Township (other) Elsewhere * Thomas Glacier (Greenland) Arts, entertainment, and media * ''Thomas'' (Burton novel) 1969 ...
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