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Dimitris Anastassiou
Dimitris Anastassiou is an electrical engineer and Charles Batchelor Professor of Electrical Engineering in the Columbia University School of Engineering. Anastassiou's earlier work focuses primarily on signal and information processing and reverse engineering. His more recent work involves interdisciplinary research, specifically in systems biology, with investigators at Columbia University Medical Center. Anastassiou is Fellow of the IEEE as well as Fellow of the National Academy of Inventors and recipient of both the National Science Foundation Presidential Young Investigator Award and the IBM Outstanding Innovation Award. Anastassiou has made significant advances in the areas of digital technology. His research resulted in Columbia being the only university to hold patent in MPEG-2 technology, a crucial technique used in all types of digital televisions, DVDs, satellite TV, HDTV, digital cable systems, computer video, and other interactive media. In 2013, a team led by A ...
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Athens
Athens ( ; el, Αθήνα, Athína ; grc, Ἀθῆναι, Athênai (pl.) ) is both the capital and largest city of Greece. With a population close to four million, it is also the seventh largest city in the European Union. Athens dominates and is the capital of the Attica region and is one of the world's oldest cities, with its recorded history spanning over 3,400 years and its earliest human presence beginning somewhere between the 11th and 7th millennia BC. Classical Athens was a powerful city-state. It was a centre for the arts, learning and philosophy, and the home of Plato's Academy and Aristotle's Lyceum. It is widely referred to as the cradle of Western civilization and the birthplace of democracy, largely because of its cultural and political influence on the European continent—particularly Ancient Rome. In modern times, Athens is a large cosmopolitan metropolis and central to economic, financial, industrial, maritime, political and cultural life in Gre ...
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National Academy Of Inventors
The National Academy of Inventors (NAI) is a US non-profit organization dedicated to encouraging inventors in academia, following the model of the National Academies of the United States. It was founded at the University of South Florida in 2010. Starting in 2012, the NAI has inducted 757 Fellows into the organization. Fellows must be named as an inventor on at least one US patent and are selected by the NAI Fellows Committee. The NAI also includes colleges and universities as institutional members, beginning with 9 such institutions in 2012; it now has over 200, including 30 outside the United States.. Since 2013, the National Academy of Inventors and the Intellectual Property Owners Association have released an annual report listing the top 100 universities by the number of US patents. The University of California has topped the list each year. The NAI has held a yearly national conference since 2011. In 2017, US Representative Dennis A. Ross introduced the bill HR 976, w ...
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Gene Expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, protein or non-coding RNA, and ultimately affect a phenotype, as the final effect. These products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) and small nuclear RNA (snRNA), the product is a functional non-coding RNA. Gene expression is summarized in the central dogma of molecular biology first formulated by Francis Crick in 1958, further developed in his 1970 article, and expanded by the subsequent discoveries of reverse transcription and RNA replication. The process of gene expression is used by all known life—eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses—to generate the macromolecular machinery for life. In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, '' ...
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Breast Cancer
Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a lack of physical exercise, alcoholism, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer. About 5–10% of cases are the result of a genetic predisposition inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly develops in cells from the lining of milk ducts and the lobules that supply these ...
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Dialogue For Reverse Engineering Assessments And Methods
DREAM Challenges (Dialogue for Reverse Engineering Assessment and Methods) is a non-profit initiative for advancing biomedical and systems biology research via crowd-sourced competitions. Started in 2006, DREAM challenges collaborate with Sage Bionetworks to provide a platform for competitions run on the Synapse platform. Over 60 DREAM challenges have been conducted over the span of over 15 years. Overview DREAM Challenges were founded in 2006 by Gustavo Stolovizky from IBM Research and Andrea Califano from Columbia University. Current chair of the DREAM organization is Paul Boutros from University of California. Further organization spans emeritus chairs Justin Guinney and Gustavo Stolovizky, and multiple DREAM directors. Individual challenges focus on tackling a specific biomedical research question, typically narrowed down to a specific disease. A prominent disease focus has been on oncology, with multiple past challenges focused on breast cancer, acute myeloid leukemia, an ...
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Sage Bionetworks
Sage Bionetworks is a nonprofit organization in Seattle that promotes open science and patient engagement in the research process. It is led by Lara Mangravite. It was co-founded by Stephen Friend and Eric Schadt. Open science Sage Bionetworks is notable for being an early advocate of open science. The company operates a software platform for collaborative data analysis called Synapse that allows researchers to work together on data curation and computational modeling asynchronously in a manner inspired by GitHub. Synapse also serves as the software infrastructure for running computational challenges. Sage is also developing a citizen-science platform called Bridge. Research The bulk of Sage's scientific results emerge from cancer and neurosciences, with notable contributions to the Cancer Genome Atlas Pan-Cancer project. Another Sage initiative, ''The Resilience Project'' describes itself as a search for individuals who have genetic changes expected to cause severe illness bu ...
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Bipolar Disorder
Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that last from days to weeks each. If the elevated mood is severe or associated with psychosis, it is called mania; if it is less severe, it is called hypomania. During mania, an individual behaves or feels abnormally energetic, happy or irritable, and they often make impulsive decisions with little regard for the consequences. There is usually also a reduced need for sleep during manic phases. During periods of depression, the individual may experience crying and have a negative outlook on life and poor eye contact with others. The risk of suicide is high; over a period of 20 years, 6% of those with bipolar disorder died by suicide, while 30–40% engaged in self-harm. Other mental health issues, such as anxiety disorders and substance use disorders, are commonly associated with bipolar disorder. While the causes of ...
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Schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a history that includes the person's reported experiences, and reports of others familiar with the person. To be diagnosed with schizophrenia, symptoms and functional impairment need to be present for six months (DSM-5) or one month (ICD-11). Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime. In 2 ...
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Maria Karayiorgou
Maria may refer to: People * Mary, mother of Jesus * Maria (given name), a popular given name in many languages Place names Extraterrestrial *170 Maria, a Main belt S-type asteroid discovered in 1877 *Lunar maria (plural of ''mare''), large, dark basaltic plains on Earth's Moon Terrestrial *Maria, Maevatanana, Madagascar *Maria, Quebec, Canada *Maria, Siquijor, the Philippines *María, Spain, in Andalusia *Îles Maria, French Polynesia *María de Huerva, Aragon, Spain *Villa Maria (other) Arts, entertainment, and media Films *Maria (1947 film), ''Maria'' (1947 film), Swedish film *Maria (1975 film), ''Maria'' (1975 film), Swedish film *Maria (2003 film), ''Maria'' (2003 film), Romanian film *Maria (2019 film), ''Maria'' (2019 film), Filipino film *Maria (2021 film), ''Maria'' (2021 film), Canadian film directed by Alec Pronovost *Maria (Sinhala film), ''Maria'' (Sinhala film), Sri Lankan upcoming film Literature *María (novel), ''María'' (novel), an 1867 novel by Jo ...
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National Institute Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institut ...
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MPEG LA
MPEG LA is an American company based in Denver, Colorado that licenses patent pools covering essential patents required for use of the MPEG-2, MPEG-4, IEEE 1394, VC-1, ATSC, MVC, MPEG-2 Systems, AVC/H.264 and HEVC standards. History MPEG LA started operations in July 1997 immediately after receiving a Department of Justice Business Review Letter. During formation of the MPEG-2 standard, a working group of companies that participated in the formation of the MPEG-2 standard recognized that the biggest challenge to adoption was efficient access to essential patents owned by many patent owners. That ultimately led to a group of various MPEG-2 patent owners to form MPEG LA, which in turn created the first modern-day patent pool as a solution. The majority of patents underlying MPEG-2 technology were owned by three companies: Sony (311 patents), Thomson (198 patents) and Mitsubishi Electric (119 patents). In June 2012, MPEG LA announced a call for patents essential to the High ...
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Videoconference
Videotelephony, also known as videoconferencing and video teleconferencing, is the two-way or multipoint reception and transmission of audio and video signals by people in different locations for real time communication.McGraw-Hill Concise Encyclopedia of EngineeringVideotelephony McGraw-Hill, 2002. Retrieved from the FreeDictionary.com website, January 9, 2010 A videophone is a telephone with a video camera and video display, capable of simultaneous video and audio communication. Videoconferencing implies the use of this technology for a group or organizational meeting rather than for individuals, in a videoconference.Mulbach et al, 1995. pg. 291. Telepresence may refer either to a high-quality videotelephony system (where the goal is to create the illusion that remote participants are in the same room) or to meetup technology, which can go beyond video into robotics (such as moving around the room or physically manipulating objects). Videoconferencing has also been called "visu ...
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