Desmanthus Illinoensis
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Desmanthus Illinoensis
''Desmanthus illinoensis'', commonly known as Illinois bundleflower, prairie-mimosa or prickleweed, is a common plant in many areas of the south central and Midwestern US. Habitat It can often be found growing on the sides of roads, needing full sun and ample moisture during its short growing season. USDA Zones 5-8 are recommended for outside cultivation. Chemistry Root bark of ''D. illinoensis'' has been found to contain N,N-DMT, NMT, N-hydroxy-N-methyltryptamine, 2-hydroxy-N-methyltryptamine, and gramine (toxic). Nutritional benefits The plant is nutritious and high in protein. The Land Institute in Salina, Kansas has done extensive research into the food uses of the seeds of this plant. Studies found the dry seeds composed of 38% protein, compared to 40% for soybeans. Ayahuasca analogue The root bark is mixed with a native source of beta-Carbolines (e.g., passion flower in North America) to produce a hallucinogenic plant concoction analogous to the shamanic Sou ...
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Midwestern US
The Midwestern United States, also referred to as the Midwest or the American Midwest, is one of four census regions of the United States Census Bureau (also known as "Region 2"). It occupies the northern central part of the United States. It was officially named the North Central Region by the Census Bureau until 1984. It is between the Northeastern United States and the Western United States, with Canada to the north and the Southern United States to the south. The Census Bureau's definition consists of 12 states in the north central United States: Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, and Wisconsin. The region generally lies on the broad Interior Plain between the states occupying the Appalachian Mountain range and the states occupying the Rocky Mountain range. Major rivers in the region include, from east to west, the Ohio River, the Upper Mississippi River, and the Missouri River. The 2020 United St ...
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N,N-DMT
''N'',''N''-Dimethyltryptamine (DMT or ''N'',''N''-DMT, SPL026) is a substituted tryptamine that occurs in many plants and animals, including human beings, and which is both a derivative and a structural analog of tryptamine. It is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. DMT has a rapid onset, intense effects, and a relatively short duration of action. For those reasons, DMT was known as the "business trip" during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as LSD or psilocybin mushrooms. DMT can be inhaled, ingested, or injected and its effects depend on the dose, as well as the mode of administration. When inhaled or injected, the effects last a short period of time: about five to 15 minutes. Effects can last three hours or more when orally ingested along with a monoamine oxidase inhibitor (MAOI), such a ...
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N-Methyltryptamine
''N''-Methyltryptamine (NMT) is a member of the substituted tryptamine chemical class and a natural product which is biosynthesized in the human body from tryptamine by certain N-methyltransferase enzymes, such as indolethylamine ''N''-methyltransferase. It is a common component in human urine. NMT is an alkaloid derived from L-tryptophan that has been found in the bark, shoots and leaves of several plant genera, including ''Virola'', ''Acacia'', ''Mimosa'', and ''Desmanthus''—often together with the related compounds ''N'',''N''-dimethyltryptamine (DMT) and 5-methoxy-''N'',''N''-dimethyltryptamine (5-MeO-DMT). Orally administered NMT appears to produce no psychoactive effects, likely as a result of extensive first-pass metabolism.Foye's principles of medicinal chemistry By William O. Foye, Thomas L. Lemke, David A. Williams However, it may become active upon combination with a MAOA inhibitor (MAOI). By vaporization NMT shows activity at 50–100 mg, with a duration o ...
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2-hydroxy-N-methyltryptamine
2-Hydroxy-''N''-methyltryptamine (2-HO-NMT) is a tryptamine and is the 2- hydroxy analog of ''N''-methyltryptamine (NMT). It is briefly mentioned in Alexander Shulgin's book ''TiHKAL'' (Tryptamines I Have Known and Loved) under the DMT entry and is stated to be found in ''Desmanthus illinoensis ''Desmanthus illinoensis'', commonly known as Illinois bundleflower, prairie-mimosa or prickleweed, is a common plant in many areas of the south central and Midwestern US. Habitat It can often be found growing on the sides of roads, needing fu ...''. See also * NMT * DMT References Tryptamines {{Psychoactive-stub ...
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Gramine
Gramine (also called donaxine) is a naturally occurring indole alkaloid present in several plant species. Gramine may play a defensive role in these plants, since it is toxic to many organisms. Occurrence Gramine has been found in the giant reed, ''Arundo donax'', ''Acer saccharinum'' (Silver Maple), ''Hordeum'', (a grass genus that includes barley) and ''Phalaris'' (another grass genus). Effects and toxicity Gramine has been found to act as an agonist of the adiponectin receptor 1 Adiponectin receptor 1 (AdipoR1) is a protein which in humans is encoded by the ''ADIPOR1'' gene. It is a member of the progestin and adipoQ receptor (PAQR) family, and is also known as PAQR1. Structure Similar to G protein-coupled receptors (GP ... (AdipoR1). The LD50 of gramine is 44.6 mg/ kg iv in mice and 62.9 mg/ kg iv in rats. Numerous studies have been done on the toxicity in insects harmful to crops for use as a possible insecticide. References {{Reflist Adiponectin receptor a ...
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Desmanthus Illinoensis Seeds
''Desmanthus'' is a genus of flowering plants in the mimosoid clade of the subfamily Caesalpinioideae of the pea family, Fabaceae. The name is derived from the Greek words δεσμός (''desmos''), meaning "bundle", and ἄνθος (''anthos''), meaning "flower". It contains about 24 species of herbs and shrubs that are sometimes described as being suffruiticose and have bipinnate leaves. ''Desmanthus'' is closely related to ''Leucaena'' and in appearance is similar to '' Neptunia''. Like ''Mimosa'' and ''Neptunia'', ''Desmanthus'' species fold their leaves in the evening. They are native to Mexico and North, Central and South America. Members of the genus are commonly known as bundleflowers. Donkey beans is another common name and originated in Central America, where ''Desmanthus'' species are highly regarded as fodder for these domestic draught animals. Description There are considerable differences in the descriptions of ''Desmanthus'' in the literature ...
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Salina, Kansas
Salina is a city in, and the county seat of, Saline County, Kansas, United States. As of the 2020 census, the population was 46,889. In the early 1800s, the Kanza tribal land reached eastward from the middle of the Kansas Territory. In 1858, settlers from Lawrence founded the Salina Town Company with a wagon circle, under constant threat of High Plains tribal attacks from the west. It was named for the salty Saline River. Saline County was soon organized around this township, and in 1870, Salina incorporated as a city. As the westernmost town on the Smoky Hill Trail, Salina boomed until the Civil War by establishing itself as a trading post for westbound immigrants, gold prospectors bound for Pikes Peak, and area American Indian tribes. It boomed again from the 1940s-1950s when the Smoky Hill Army Airfield was built for World War II strategic bombers. It is now a micropolis and regional trade center for North Central Kansas. Higher education institutions include th ...
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Soybean
The soybean, soy bean, or soya bean (''Glycine max'') is a species of legume native to East Asia, widely grown for its edible bean, which has numerous uses. Traditional unfermented food uses of soybeans include soy milk, from which tofu and tofu skin are made. Fermented soy foods include soy sauce, fermented bean paste, nattō, and tempeh. Fat-free (defatted) soybean meal is a significant and cheap source of protein for animal feeds and many packaged meals. For example, soybean products, such as textured vegetable protein (TVP), are ingredients in many meat and dairy substitutes. Soybeans contain significant amounts of phytic acid, dietary minerals and B vitamins. Soy vegetable oil, used in food and industrial applications, is another product of processing the soybean crop. Soybean is the most important protein source for feed farm animals (that in turn yields animal protein for human consumption). Etymology The word "soy" originated as a corruption of the Cantonese or ...
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Beta-Carboline
β-Carboline (9''H''- pyrido ,4-''b'' ndole) represents the basic chemical structure for more than one hundred alkaloids and synthetic compounds. The effects of these substances depend on their respective substituent. Natural β-carbolines primarily influence brain functions but can also exhibit antioxidant effects. Synthetically designed β-carboline derivatives have recently been shown to have neuroprotective, cognitive enhancing and anti-cancer properties. Pharmacology The pharmacological effects of specific β-carbolines are dependent on their substituents. For example, the natural β-carboline harmine has substituents on position 7 and 1. Thereby, it acts as a selective inhibitor of the DYRK1A protein kinase, a molecule necessary for neurodevelopment. It also exhibits various antidepressant-like effects in rats by interacting with serotonin receptor 2A. Furthermore, it increases levels of the brain-derived neurotrophic factor (BDNF) in rat hippocampus. A decreased BDNF le ...
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Passiflora Incarnata
''Passiflora incarnata'', commonly known as maypop, purple passionflower, true passionflower, wild apricot, and wild passion vine, is a fast-growing perennial vine with climbing or trailing stems. A member of the passionflower genus ''Passiflora'', the maypop has large, intricate flowers with prominent styles and stamens. One of the hardiest species of passionflower, it is both found as a wildflower in the southern United States and in cultivation for its fruit and striking bluish purple blooms. ''Passiflora incarnata'' fruit contain many seeds, each surrounded by an aril holding edible juice, and this juice can be consumed fresh or used to flavor processed products. Description The stems can be smooth or pubescent; they are long and trailing, possessing many tendrils. Leaves are alternate and palmately 3-lobed and occasionally 5-lobed, measuring . They have two characteristic glands at the base of the blade on the petiole. Flowers have five bluish-white petals. They exhibit a ...
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Concoction
Concoction is the process of preparing a medicine, food or other substance out of many ingredients, and also the result of such a process. Historically, the word referred to digestion, as conceived by Aristotle who theorized that this was the result of the heat of the body acting upon the material, causing it to mature and ripen. The term later came to refer to liquid broths, cocktails and potions which are similarly formed by heating or blending multiple ingredients. Concoctions that were made in apothecaries, or as used in traditional medicine, , rather than nourishment or pleasure (in which case it would be cookery or cuisine). In a medical context, such concoctions have largely been superseded by modern medicine. In modern usage, the term may refer more loosely to any mixture of various ingredients, including soups and cocktails, or abstract ingredients, such as design elements in architecture or fashion, or an elaborate excuse. In such uses, the term often retains a connota ...
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Shamanism
Shamanism is a religious practice that involves a practitioner (shaman) interacting with what they believe to be a Spirit world (Spiritualism), spirit world through Altered state of consciousness, altered states of consciousness, such as trance. The goal of this is usually to direct Non-physical entity, spirits or Energy (esotericism), spiritual energies into the physical world for the purpose of healing, divination, or to aid human beings in some other way. Beliefs and practices categorized as "shamanic" have attracted the interest of scholars from a variety of disciplines, including anthropologists, archeologists, historians, religious studies scholars, philosophers and psychologists. Hundreds of books and Academic publishing#Scholarly paper, academic papers on the subject have been produced, with a peer-reviewed academic journal being devoted to the study of shamanism. In the 20th century, non-Indigenous Peoples, Indigenous Westerners involved in countercultural movements, ...
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