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Dermatology Life Quality Index
The Dermatology life Quality Index (DLQI) is a ten-question questionnaire used to measure the impact of skin disease on the quality of life of an affected person. It is designed for people aged 16 years and above. History The DLQI was created by Andrew Y Finlay and Gul Karim Khan from 1990 to 1994 at the Department of Dermatology, University of Wales College of Medicine (now Cardiff University), Cardiff, UK. 120 patients with a variety of skin diseases completed a questionnaire that asked them to write down all of the ways that their skin disease affected their lives. 49 different ways were identified, and these were used as the basis of the questions of the DLQI. The DLQI was first presented at the British Association of Dermatologists annual meeting in July 1993 and described in an article published in 1994 in ''Clinical and Experimental Dermatology''. This article has become one of the most frequently cited articles in clinical dermatology. The DLQI is the most frequently us ...
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Cutaneous Condition
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia and racquet nails). While only a small number of skin diseases account for most visits to the physician, thousands of skin conditions have been described. Classification of these conditions often presents many nosological challenges, since underlying causes and pathogenetics are often not known. Therefore, most current textbooks present a classification based on location (for example, conditions of the mucous membrane), morphology ( chronic blistering conditions), cause (skin conditions result ...
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Cardiff University School Of Medicine
The Cardiff University School of Medicine ( cy, Ysgol Feddygaeth Prifysgol Caerdydd) is the medical school of Cardiff University and is located in Cardiff, Wales, UK. Founded in 1893 as part of the University College of South Wales and Monmouthshire, it is the older of the two medical schools in Wales. It is one of the largest medical schools in the United Kingdom, employing nearly 500 academic and 300 support staff; and with over 1000 undergraduate and 1100 postgraduate students enrolled on medical and scientific courses. The school has an annual financial turnover of over £50 million, of which nearly half comes from competitive external research funding. The school is based at the University Hospital of Wales in Cardiff. History Origins The medical school was founded as ''Cardiff Medical School'' in 1893 when the Departments of Anatomy, Physiology and Pharmacology were established at University College of South Wales and Monmouthshire (now Cardiff University). Much of th ...
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British Association Of Dermatologists
The British Association of Dermatologists is a charity established in 1920 whose charitable objects are the practice, teaching, training, and research of dermatology. It produces the ''British Journal of Dermatology The ''British Journal of Dermatology'' is a monthly peer-reviewed medical journal that covers the field of dermatology. It is published by Wiley-Blackwell on behalf of the British Association of Dermatologists. The journal was established in 18 ...'', a monthly peer-reviewed medical journal and organises annual conferences. Notable presidents References External linksBritish Association of Dermatologists Dermatology organizations Health in the London Borough of Camden Medical associations based in the United Kingdom 1920 establishments in the United Kingdom Organisations based in the London Borough of Camden Presidents of the British Association of Dermatologists {{UK-charity-stub ...
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Psoriasis
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by raised areas of abnormal skin. These areas are red, pink, or purple, dry, itchy, and scaly. Psoriasis varies in severity from small, localized patches to complete body coverage. Injury to the skin can trigger psoriatic skin changes at that spot, which is known as the Koebner phenomenon. The five main types of psoriasis are plaque, guttate, inverse, pustular, and erythrodermic. Plaque psoriasis, also known as psoriasis vulgaris, makes up about 90% of cases. It typically presents as red patches with white scales on top. Areas of the body most commonly affected are the back of the forearms, shins, navel area, and scalp. Guttate psoriasis has drop-shaped lesions. Pustular psoriasis presents as small, noninfectious, pus-filled blisters. Inverse psoriasis forms red patches in skin folds. Erythrodermic psoriasis occurs when the rash becomes very widespread, and can develop from any of the other types. ...
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Chris Griffiths (dermatologist)
Christopher Ernest Maitland Griffiths (born June 1954) is Foundation Professor of Dermatology at the University of Manchester, Director of the Manchester Centre for Dermatology Research, and Head of the Dermatology Theme of the National Institute for Health Research (NIHR) Manchester Biomedical Research Centre. He is an Honorary Consultant Dermatologist at Salford Royal NHS Foundation Trust. Griffiths graduated with a first-class degree in Anatomy from St Thomas's Hospital Medical School in 1976 and completed an MBBS in Medicine in 1979. He trained in Dermatology at St Mary's Hospital, London, where he was a Wellcome Trust Clinical Research Training Fellow from 1985 to 1987. In 1987 he became a research fellow in Dermatology at the University of Michigan, becoming an Assistant Professor from 1989 to 1993. He founded the Manchester Dermatopharmacology Unit and the Manchester Psoriasis Service in 1994, and co-founded the International Psoriasis Council in 2004. He was President of ...
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Body Surface Area
In physiology and medicine, the body surface area (BSA) is the measured or calculated surface area of a human body. For many clinical purposes, BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass. Nevertheless, there have been several important critiques of the use of BSA in determining the dosage of medications with a narrow therapeutic index, such as chemotherapy. Typically there is a 4–10 fold variation in drug clearance between individuals due to differing the activity of drug elimination processes related to genetic and environmental factors. This can lead to significant overdosing and underdosing (and increased risk of disease recurrence). It is also thought to be a distorting factor in Phase I and II trials that may result in potentially helpful medications being prematurely rejected. The trend to personalized medicine is one approach to counter this weakness. Uses Examples of uses of the BSA: * Renal clearan ...
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Immunotherapy
Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as ''activation immunotherapies,'' while immunotherapies that reduce or suppress are classified as '' suppression immunotherapies''. Immunotherapy is under preliminary research for its potential to treat various forms of cancer. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural killer cells, and cytotoxic T lymphocytes work together to defend the body against cancer by targeting abnormal antigens expressed on the surface of tumor cells. Vaccine-induced immunity to COVID-19 relies mostly on an immunomodulatory T cell response. Therapies such as granulocyte colony-stimulating factor (G-CSF), interferons, imiquimod and cellular membrane fractions from bacteria are licensed for medical use. Others includin ...
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Copyright
A copyright is a type of intellectual property that gives its owner the exclusive right to copy, distribute, adapt, display, and perform a creative work, usually for a limited time. The creative work may be in a literary, artistic, educational, or musical form. Copyright is intended to protect the original expression of an idea in the form of a creative work, but not the idea itself. A copyright is subject to limitations based on public interest considerations, such as the fair use doctrine in the United States. Some jurisdictions require "fixing" copyrighted works in a tangible form. It is often shared among multiple authors, each of whom holds a set of rights to use or license the work, and who are commonly referred to as rights holders. These rights frequently include reproduction, control over derivative works, distribution, public performance, and moral rights such as attribution. Copyrights can be granted by public law and are in that case considered "territorial righ ...
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