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Denis Wirtz
Denis Wirtz is the vice provost for research and Theophilus Halley Smoot Professor of Engineering Science at Johns Hopkins University. He is an expert in the molecular and biophysical mechanisms of cell motility and adhesion and nuclear dynamics in health and disease. Wirtz was the first to establish how a three-dimensional environment fundamentally affects the way cancer cells migrate, providing more biologically and medically relevant information than two-dimensional studies. He also pioneered the technique of particle-tracking microrheology to probe the rheological properties of complex fluids and living cells and tissues. He is a professor in the Departments of Chemical Engineering & Biomolecular Engineering and Materials Science & Engineering in the Whiting School of Engineering, and in the Departments of Oncology and Pathology in the Johns Hopkins School of Medicine. Wirtz was named vice provost for research in February 2014, charged with directing the university's $2.24 bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brussels
Brussels (french: Bruxelles or ; nl, Brussel ), officially the Brussels-Capital Region (All text and all but one graphic show the English name as Brussels-Capital Region.) (french: link=no, Région de Bruxelles-Capitale; nl, link=no, Brussels Hoofdstedelijk Gewest), is a region of Belgium comprising 19 municipalities, including the City of Brussels, which is the capital of Belgium. The Brussels-Capital Region is located in the central portion of the country and is a part of both the French Community of Belgium and the Flemish Community, but is separate from the Flemish Region (within which it forms an enclave) and the Walloon Region. Brussels is the most densely populated region in Belgium, and although it has the highest GDP per capita, it has the lowest available income per household. The Brussels Region covers , a relatively small area compared to the two other regions, and has a population of over 1.2 million. The five times larger metropolitan area of Brusse ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AAAS Fellow
Fellowship of the American Association for the Advancement of Science (FAAAS) is an honor accorded by the American Association for the Advancement of Science (AAAS) to distinguished persons who are members of the Association. Fellows are elected annually by the AAAS Council for "efforts on behalf of the advancement of science or its applications hichare scientifically or socially distinguished". Examples of areas in which nominees may have made significant contributions are research; teaching; technology; services to professional societies; administration in academe, industry, and government; and communicating and interpreting science to the public. The association has awarded fellowships since 1874. AAAS publishes annual update of active Fellows list, which also provides email address to verify status of non-active Fellows. See also :Fellows of the American Association for the Advancement of Science for more examples. AAAS Fellows AAAS Fellows include Nobel Prize winners M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johns Hopkins School Of Medicine
The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospital and Johns Hopkins Children's Center, established in 1889. It has consistently ranked among the top medical schools in the United States in terms of the number/amount of research grants/funding awarded by the National Institutes of Health, among other measures. History The founding physicians (the "Four Doctors") of the Johns Hopkins School of Medicine included pathologist William Henry Welch (1850–1934), the first dean of the school and a mentor to generations of research scientists; a Canadian, internist Sir William Osler (1849–1919), regarded as the ''Father of Modern Medicine'', having been perhaps the most influential physician of the late 19th and early 20th centuries as author of '' The Principles and Practice of Medicine'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whiting School Of Engineering
The G.W.C. Whiting School of Engineering is the engineering college of the Johns Hopkins University, a private research university in Baltimore, Maryland. History Engineering at Johns Hopkins was originally created in 1913 as an educational program that included exposure to liberal arts and scientific inquiry. In 1919, the engineering department became a separate school, known as the School of Engineering. By 1937, over 1,000 students had graduated with engineering degrees. By 1946 the school had six departments. In 1961, the School of Engineering changed its name to the School of Engineering Sciences and, in 1966, merged with the Faculty of Philosophy to become part of the School of Arts and Sciences. In 1979, the engineering programs were organized into a separate academic division that was named the G.W.C. Whiting School of Engineering. The school's named benefactor is George William Carlyle Whiting, co-founder of The Whiting-Turner Contracting Company. Several department ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rheological
Rheology (; ) is the study of the flow of matter, primarily in a fluid (liquid or gas) state, but also as "soft solids" or solids under conditions in which they respond with plastic flow rather than deforming elastically in response to an applied force. Rheology is a branch of physics, and it is the science that deals with the deformation and flow of materials, both solids and liquids.W. R. Schowalter (1978) Mechanics of Non-Newtonian Fluids Pergamon The term ''rheology'' was coined by Eugene C. Bingham, a professor at Lafayette College, in 1920, from a suggestion by a colleague, Markus Reiner.The Deborah Number The term was inspired by the of |
Microrheology
Microrheology is a technique used to measure the rheological properties of a medium, such as microviscosity, via the measurement of the trajectory of a flow tracer (a micrometre-sized particle). It is a new way of doing rheology, traditionally done using a rheometer. There are two types of microrheology: ''passive microrheology'' and ''active microrheology''. Passive microrheology uses inherent thermal energy to move the tracers, whereas active microrheology uses externally applied forces, such as from a magnetic field or an optical tweezer, to do so. Microrheology can be further differentiated into 1- and 2-particle methods. Passive microrheology '' Passive microrheology '' uses the thermal energy (''kT'') to move the tracers, although recent evidence suggests that active random forces inside cells may instead move the tracers in a diffusive-like manner. The trajectories of the tracers are measured optically either by microscopy, or alternatively by light scattering techniqu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Adhesion
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released by cells into spaces between them. Cells adhesion occurs from the interactions between cell-adhesion molecules (CAMs), transmembrane proteins located on the cell surface. Cell adhesion links cells in different ways and can be involved in signal transduction for cells to detect and respond to changes in the surroundings. Other cellular processes regulated by cell adhesion include cell migration and tissue development in multicellular organisms. Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthritis. Cell adhesion is also essential for in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Migration
Cell migration is a central process in the development and maintenance of multicellular organisms. Tissue formation during embryonic development, wound healing and immune responses all require the orchestrated movement of cells in particular directions to specific locations. Cells often migrate in response to specific external signals, including chemical signals and mechanical signals. Errors during this process have serious consequences, including intellectual disability, vascular disease, tumor formation and metastasis. An understanding of the mechanism by which cells migrate may lead to the development of novel therapeutic strategies for controlling, for example, invasive tumour cells. Due to the highly viscous environment (low Reynolds number), cells need to continuously produce forces in order to move. Cells achieve active movement by very different mechanisms. Many less complex prokaryotic organisms (and sperm cells) use flagella or cilia to propel themselves. Eukaryot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892.Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and biochemistry. Overview ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Mechanics
Molecular mechanics uses classical mechanics to model molecular systems. The Born–Oppenheimer approximation is assumed valid and the potential energy of all systems is calculated as a function of the nuclear coordinates using force fields. Molecular mechanics can be used to study molecule systems ranging in size and complexity from small to large biological systems or material assemblies with many thousands to millions of atoms. All-atomistic molecular mechanics methods have the following properties: * Each atom is simulated as one particle * Each particle is assigned a radius (typically the van der Waals radius), polarizability, and a constant net charge (generally derived from quantum calculations and/or experiment) * Bonded interactions are treated as ''springs'' with an equilibrium distance equal to the experimental or calculated bond length Variants on this theme are possible. For example, many simulations have historically used a ''united-atom'' representation in which ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academies Of Belgium
In Belgium, academies are publicly funded learned societies, often divided by academic discipline or linguistic group. Besides holding meetings, many publish academic monographs, peer-reviewed journals and hold conferences. Membership is usually by election and non-Belgians are usually admitted only as corresponding members. Originating during the Enlightenment, the concept can be traced to the Imperial and Royal Academy of Brussels which was the first academy in Belgium, founded in 1772 by the Empress Maria Theresa when the country was under Austrian rule. The principle academies in Belgium are interdisciplinary but divided linguistically. Both trace their origins to the original academy of 1772 and are based in the Academy Palace in Brussels, which also houses three others. They are: * Royal Academy of Sciences, Literature and Fine Arts of Belgium, a French-speaking institution known as the "Theresean Academy"; * Royal Flemish Academy of Belgium for Science and the Arts (KV ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Belgian American Educational Foundation
The Belgian American Educational Foundation (BAEF) is an educational charity. It supports the exchange of university students, scientists and scholars between the United States and Belgium. The foundation fosters the higher education of deserving Belgians and Americans through its exchange-fellowship program. Since 1977, Dr. Emile Boulpaep is the president of the BAEF. History During World War I, from October 1914, Herbert Hoover organized the Committee for Relief in Belgium (USA) and the ''Commission for Relief in Belgium'' (Belgium). After the war, the University Foundation, and on 9 January 1920, the B.A.E.F., were founded with the budget remaining in the hands of the commission after five years of relief work. The ''Belgian American Educational Foundation'' became the heir of the Commission for Relief in Belgium. After World War I, the BAEF invested in land and buildings for the Université libre de Bruxelles (Solbosch campus) and also for rebuilding the library of the Catho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
