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Delcath Systems, Inc.
Delcath Systems, Inc. (NASDAQ: DCTH) is a publicly traded specialty pharmaceutical and medical device company, that develops percutaneous perfusion technologies for the targeted administration of high-dose chemotherapeutic agents to specific organs or regions of the body. Based in Queensbury, New York, the company has an intellectual property portfolio consisting of 28 patents worldwide. Delcath's Percutaneous Hepatic Perfusion (PHP) is currently undergoing Phase II and Phase III trials against tumors in the liver. Delcath has a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute and has received Fast Track and a Special Protocol Assessment from the Food and Drug Administration for its use of melphalan in treating unresectable liver tumors. PHP, also known as the Delcath System, is tested for the treatment of metastatic melanoma in the liver and for primary liver cancer and metastatic hepatic malignancies from neuroendocrine ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilmington, Delaware
Wilmington ( Lenape: ''Paxahakink /'' ''Pakehakink)'' is the largest city in the U.S. state of Delaware. The city was built on the site of Fort Christina, the first Swedish settlement in North America. It lies at the confluence of the Christina River and Brandywine Creek, near where the Christina flows into the Delaware River. It is the county seat of New Castle County and one of the major cities in the Delaware Valley metropolitan area. Wilmington was named by Proprietor Thomas Penn after his friend Spencer Compton, Earl of Wilmington, who was prime minister during the reign of George II of Great Britain. At the 2020 census, the city's population was 70,898. The Wilmington Metropolitan Division, comprising New Castle County, Delaware, Cecil County, Maryland and Salem County, New Jersey, had an estimated 2016 population of 719,887. Wilmington is part of the Delaware Valley metropolitan statistical area, which also includes Philadelphia, Reading, Camden, and other urban are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melanoma
Melanoma, also redundantly known as malignant melanoma, is a type of skin cancer that develops from the pigment-producing cells known as melanocytes. Melanomas typically occur in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). In women, they most commonly occur on the legs, while in men, they most commonly occur on the back. About 25% of melanomas develop from moles. Changes in a mole that can indicate melanoma include an increase in size, irregular edges, change in color, itchiness, or skin breakdown. The primary cause of melanoma is ultraviolet light (UV) exposure in those with low levels of the skin pigment melanin. The UV light may be from the sun or other sources, such as tanning devices. Those with many moles, a history of affected family members, and poor immune function are at greater risk. A number of rare genetic conditions, such as xeroderma pigmentosum, also increase the risk. Diagnosis is by biopsy and analysis of any skin lesion ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Maryland Medical Center Midtown Campus
University of Maryland Medical Center Midtown Campus (formerly Maryland General Hospital) is a hospital in the downtown area of Baltimore, Maryland. The hospital was founded for teaching purposes in 1881 by a group of local doctors. The hospital has been affiliated with the University of Maryland Medical System since 1999, and has over 1,400 employees and 500 doctors, covering 30 different specialties. Originally known as the Baltimore Medical College, it affiliated with the University of Maryland School of Medicine in 1911. An affiliation with the Baltimore Eye, Ear, Nose and Throat Hospital began in 1965. The hospital became part of the University of Maryland Medical System in 1999. Maryland General opened its own nursing school in 1893. The last class of the Maryland General Hospital School of Nursing graduated in January 1987, when the hospital's nursing school closed. The Obstetrics Service at Maryland General was discontinued effective June 30, 2013, due to declining volume ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swedish Medical Center (Colorado)
:''This article refers to the hospital in Englewood, Colorado. For the hospital in Seattle, Washington, see Swedish Medical Center.'' Swedish Medical Center is a 408-bed acute care hospital located in Englewood, Colorado, United States. It is a Level I trauma and burn center serving Colorado and the Rocky Mountain region. It is operated by HealthONE, part of HCA Healthcare's Continental Division. History Swedish Medical Center was founded in 1905 in Colorado as a tuberculosis sanatorium. In 1924, the hospital was expanded with funds donated by the Swedish Women of Chicago. In 1956, with the decline of TB as a major health threat, the hospital's focus turned to general healthcare. Swedish Medical Center was the first hospital in Colorado to use MRI and CT technology, as well as angiography. Swedish is a regional referral center for neurotrauma and in 2003 it was designated one of the three Level I Trauma Centers in Colorado. Swedish also became the first Comprehensive Stroke ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morristown Medical Center
Morristown Medical Center (MMC) is a 735 bed non-profit, tertiary, research and academic medical center located in Morristown, New Jersey, serving northern New Jersey and the New York metropolitan area. The hospital is the flagship facility of Atlantic Health System and is the largest medical center in the system. Morristown Medical Center is affiliated with the Sidney Kimmel School of Medicine at Thomas Jefferson University. The facility is an American College of Surgeons designated Level I and Level 2 trauma center by the State of New Jersey and has a rooftop helipad to receive and dispatch medevac patients. Goryeb Children's Hospital is located on the campus of Morristown Medical Center and specializes in the treatment of infants, children, adolescents, and young adults up to the age of 21. Morristown Medical Center was established in 1892. With approximately 7,000 employees, it is Morristown's largest employer and one of the largest employers in Morris County, New J ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albany Medical Center
Albany Medical Center (AMC) is the name of the umbrella organization over the Albany Medical Center Hospital and Albany Medical College in Albany, New York. Though the name Albany Medical Center referring to the two institutions on their shared campus has been used for over a century, the two institutions were independent until the formation of the formal Albany Medical Center in 1982. AMC awards the Albany Medical Center Prize, the second-highest value prize in medicine and biomedical research in the United States, annually. Within AMCH is the Bernard & Millie Duker Children's Hospital that treats infants, children, teens, and young adults aged 0–21 throughout the region. History In 1839, Dr. Alden March and Dr. James H. Armsby founded Albany Medical College in the former Lancaster School at the corner of Lancaster and Eagle Streets in the City of Albany. Albany Hospital was incorporated in 1849 and established two years later on the southwest corner of Dove Street and Lydius ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Pittsburgh Medical Center
The University of Pittsburgh Medical Center (UPMC) is a $23billion integrated global nonprofit health enterprise that has 92,000 employees, 40 hospitals with more than 8,000 licensed beds, 800 clinical locations including outpatient sites and doctors' offices, a 3.8million-member health insurance division, as well as commercial and international ventures.Updated with Sept 1 merger with Pinnacle Health UPMC, http://www.pinnaclehealth.org/our-health-system/news-and-announcements/article/pinnaclehealth-joins-upmc-to-expand-health-care-services-advance-quality-care It is closely affiliated with its academic partner, the University of Pittsburgh. It is considered a leading American health care provider, as its flagship facilities have ranked in '' U.S. News & World Report'' "Honor Roll" of the approximately 15 to 20 best hospitals in America for over 15 years. As of 2016, its flagship hospital UPMC Presbyterian is ranked 12th nationally among the best hospitals (and first in Pennsylva ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Capecitabine
Capecitabine, sold under the brand name Xeloda among others, is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer. For breast cancer it is often used together with docetaxel. It is taken by mouth. Common side effects include abdominal pain, vomiting, diarrhea, weakness, and rashes. Other severe side effects include blood clotting problems, allergic reactions, heart problems such as cardiomyopathy, and low blood cell counts. It is not recommended in people with kidney problems. Use during pregnancy may result in harm to the fetus. Capecitabine, inside the body, is converted to 5-fluorouracil (5-FU) through which it acts. It belongs to the class of medications known as fluoropyrimidines, which also includes 5-FU and tegafur. Capecitabine was patented in 1992 and approved for medical use in 1998. It is on the World Health Organization's List of Essential Medicines. Medical uses It is used in the treatment of the following cancers: * Co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Busulfan
Busulfan (Myleran, GlaxoSmithKline, Busulfex IV, Otsuka America Pharmaceutical, Inc.) is a chemotherapy drug in use since 1959. It is a cell cycle non-specific alkylating antineoplastic agent, in the class of alkyl sulfonates. Its chemical designation is 1,4-butanediol dimethanesulfonate. History Busulfan was approved by the US Food and Drug Administration (FDA) for treatment of chronic myeloid leukemia (CML) in 1999. Busulfan was the mainstay of the chemotherapeutic treatment of chronic myeloid leukemia (CML) until it was displaced by the new gold standard, imatinib, though it is still in use to a degree as a result of the drug's relative low cost. Indications Busulfan is used in pediatrics and adults in combination with cyclophosphamide or fludarabine/clofarabine as a conditioning agent prior to bone marrow transplantation, especially in chronic myelogenous leukemia (CML) and other leukemias, lymphomas, and myeloproliferative disorders. Busulfan can control tumor burden ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intravenous Therapy
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth. It may also be used to administer medications or other medical therapy such as blood products or electrolytes to correct electrolyte imbalances. Attempts at providing intravenous therapy have been recorded as early as the 1400s, but the practice did not become widespread until the 1900s after the development of techniques for safe, effective use. The intravenous route is the fastest way to deliver medications and fluid replacement throughout the body as they are introduced directly into the circulatory system and thus quickly distributed. For this reason, the intravenous route of administration is also used for the consump ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Route Of Administration
A route of administration in pharmacology and toxicology is the way by which a medication, drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral administration, oral and intravenous therapy, intravenous administration. Routes can also be classified based on where the target of action is. Action may be topical medication, topical (local), enteral administration, enteral (system-wide effect, but delivered through the gastrointestinal tract), or #Parenteral, parenteral (systemic action, but delivered by routes other than the GI tract). Route of administration and dosage form are aspects of drug delivery. Classification Routes of administration are usually classified by application location (or exposition). The route or course the active substance takes from application location to the location where it has its target effect is usually rather ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenocarcinomas
Adenocarcinoma (; plural adenocarcinomas or adenocarcinomata ) (AC) is a type of cancerous tumor that can occur in several parts of the body. It is defined as neoplasia of epithelial tissue that has glandular origin, glandular characteristics, or both. Adenocarcinomas are part of the larger grouping of carcinomas, but are also sometimes called by more precise terms omitting the word, where these exist. Thus invasive ductal carcinoma, the most common form of breast cancer, is adenocarcinoma but does not use the term in its name—however, esophageal adenocarcinoma does to distinguish it from the other common type of esophageal cancer, esophageal squamous cell carcinoma. Several of the most common forms of cancer are adenocarcinomas, and the various sorts of adenocarcinoma vary greatly in all their aspects, so that few useful generalizations can be made about them. In the most specific usage (narrowest sense), the glandular origin or traits are exocrine; endocrine gland tumors, suc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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