David R. Brown (neuroscientist)
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David R. Brown (neuroscientist)
Professor David Ronald Brown (born 7 September 1964, Sydney, Australia) is an Australian-born research scientist notable for his work on prion diseases, which include bovine spongiform encephalopathy and vCJD. His most notable research relates to the metal binding of the protein central to these diseases, the prion protein, and its possible cellular role as an antioxidant. Brown was a member of the Spongiform Encephalopathy Advisory Committee (SEAC), a British government advisory board on BSE and related diseases. Since then he has pursued research related to other neurodegenerative diseases.Research Profile
University of Bath


Career

Brown completed his studies at the

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Sydney
Sydney ( ) is the capital city of the state of New South Wales, and the most populous city in both Australia and Oceania. Located on Australia's east coast, the metropolis surrounds Sydney Harbour and extends about towards the Blue Mountains to the west, Hawkesbury to the north, the Royal National Park to the south and Macarthur to the south-west. Sydney is made up of 658 suburbs, spread across 33 local government areas. Residents of the city are known as "Sydneysiders". The 2021 census recorded the population of Greater Sydney as 5,231,150, meaning the city is home to approximately 66% of the state's population. Estimated resident population, 30 June 2017. Nicknames of the city include the 'Emerald City' and the 'Harbour City'. Aboriginal Australians have inhabited the Greater Sydney region for at least 30,000 years, and Aboriginal engravings and cultural sites are common throughout Greater Sydney. The traditional custodians of the land on which modern Sydney stands are ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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Academics Of The University Of Bath
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, dev ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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1964 Births
Events January * January 1 – The Federation of Rhodesia and Nyasaland is dissolved. * January 5 - In the first meeting between leaders of the Roman Catholic and Orthodox churches since the fifteenth century, Pope Paul VI and Patriarch Athenagoras I of Constantinople meet in Jerusalem. * January 6 – A British firm, the Leyland Motor Corp., announces the sale of 450 buses to the Cuban government, challenging the United States blockade of Cuba. * January 9 – ''Martyrs' Day'': Armed clashes between United States troops and Panamanian civilians in the Panama Canal Zone precipitate a major international crisis, resulting in the deaths of 21 Panamanians and 4 U.S. soldiers. * January 11 – United States Surgeon General Luther Terry reports that smoking may be hazardous to one's health (the first such statement from the U.S. government). * January 12 ** Zanzibar Revolution: The predominantly Arab government of Zanzibar is overthrown by African nationalist rebels; a ...
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Charles, Prince Of Wales
Charles III (Charles Philip Arthur George; born 14 November 1948) is King of the United Kingdom and the 14 other Commonwealth realms. He was the longest-serving heir apparent and Prince of Wales and, at age 73, became the oldest person to accede to the British throne following the death of his mother, Elizabeth II, on 8 September 2022. Charles was born in Buckingham Palace during the reign of his maternal grandfather, King George VI, and was three when his mother ascended the throne in 1952, making him the heir apparent. He was made Prince of Wales in 1958 and his investiture was held in 1969. He was educated at Cheam and Gordonstoun schools, as was his father, Prince Philip, Duke of Edinburgh. Charles later spent six months at the Timbertop campus of Geelong Grammar School in Victoria, Australia. After earning a Bachelor of Arts degree from the University of Cambridge, Charles served in the Air Force and Navy from 1971 to 1976. In 1981, he married Lady Diana Spencer, ...
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Chelation Therapy
Chelation therapy is a medical procedure that involves the administration of Chelation, chelating agents to remove heavy metals from the body. Chelation therapy has a long history of use in clinical toxicology and remains in use for some very specific medical treatments, although it is administered under very careful medical supervision due to various inherent risks, including the mobilization of mercury and other metals through the brain and other parts of the body by the use of weak chelating agents that unbind with metals before elimination, exacerbating existing damage. To avoid mobilization, some practitioners of chelation use strong chelators, such as selenium, taken at low doses over a long period of time. Chelation therapy must be administered with care as it has a number of possible side effects, including death. In response to increasing use of chelation therapy as alternative medicine and in circumstances in which the therapy should not be used in conventional medicine ...
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Manganese
Manganese is a chemical element with the symbol Mn and atomic number 25. It is a hard, brittle, silvery metal, often found in minerals in combination with iron. Manganese is a transition metal with a multifaceted array of industrial alloy uses, particularly in stainless steels. It improves strength, workability, and resistance to wear. Manganese oxide is used as an oxidising agent; as a rubber additive; and in glass making, fertilisers, and ceramics. Manganese sulfate can be used as a fungicide. Manganese is also an essential human dietary element, important in macronutrient metabolism, bone formation, and free radical defense systems. It is a critical component in dozens of proteins and enzymes. It is found mostly in the bones, but also the liver, kidneys, and brain. In the human brain, the manganese is bound to manganese metalloproteins, most notably glutamine synthetase in astrocytes. Manganese was first isolated in 1774. It is familiar in the laboratory in the form of the ...
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Mark Purdey
John Mark Purdey (25 December 1953 – 12 November 2006) was an English organic farmer who came to public attention in the 1980s, when he began to circulate his own theories regarding the causes of bovine spongiform encephalopathy (BSE or "mad cow disease")."Mark Purdey"
''The Daily Telegraph'', 18 November 2006.


Investigations into BSE

Purdey's interest in the disease was triggered when four cows he purchased for his farm developed the disease, though no animal raised on his farm ever contracted it.
, ''markpurdey.com''.
He also became aware of a fact also considered by the Philips Inquiry: "1145. The practice in the UK of recycling animal p ...
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Journal Of Neurochemistry
The ''Journal of Neurochemistry'' is a biweekly peer-reviewed scientific journal covering all aspects of neurochemistry. It is published by Wiley-Blackwell on behalf of the International Society for Neurochemistry and was established in 1956. The editor-in-chief is Andrew J. Lawrence (University of Melbourne). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 5.372. Abstracting and indexing The journal is abstracted and indexed in: Editors-in-chief The following persons have been editor-in-chief of the journal: References External links * {{DEFAULTSORT:Journal Of Neurochemistry Neuroscience journals Wiley-Blackwell academic journals Publications established in 1956 English-language j ...
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University Of Bath
(Virgil, Georgics II) , mottoeng = Learn the culture proper to each after its kind , established = 1886 (Merchant Venturers Technical College) 1960 (Bristol College of Science and Technology) 1966 (Bath University of Technology) 1971 (university status) , type = Public , endowment = £8.1 million (2021) , budget = £289.5 million (2020–21) , chancellor = The Earl of Wessex , vice_chancellor = Ian H. White , academic_staff = 2,180 (2020) - including academic atypical staff , students = () , undergrad = () , postgrad = () , doctoral = , city = Bath, Somerset , country = England , coor = , campus = Suburban , free_label = , free = , website www.bath.ac.uk, logo = University of Bath logo.svg , affiliations = Association of Commonwealth Universities, ACUAssociation of MBAs, AMBAEuropean Quality Improvement System, EQUISEuropean University Association, EUAUniversities UK Wallace Group (universities), Wallace GroupGW4Sutton_Trust_30, Sutton 30SETs ...
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