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David Jack (pharmacologist)
Sir David Jack (22 February 1924 – 8 November 2011) was a Scottish pharmacologist and medicinal chemist who specialised in the development of drugs for treating asthma. He was head of research and development at Glaxo from 1978 until 1987. Early life and education Jack was born the sixth and youngest child of a coal miner, in Markinch, Fife, Scotland. He attended Buckhaven High School before turning down a place at Edinburgh University to become an apprentice pharmacist. In 1944, having completed his apprenticeship, he began a BSc course in chemistry and pharmacy at the Royal Technical College, Glasgow. He won a number of undergraduate prizes and graduated with first class honours. Career He turned down an offer to study for a doctorate and instead worked as an assistant lecturer at the University of Glasgow. In 1951 he joined the pharmaceutical company Glaxo Laboratories, moving to Smith Kline and French in 1953. In 1961 he became director of research at Allen an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Markinch
Markinch (, (Scottish Gaelic: Marc Innis) is both a village and a parish in the heart of Fife, Scotland. According to an estimate taken in 2008, the village has a population of 2,420. The civil parish had a population of 16,530 (in 2011).Census of Scotland 2011, Table KS101SC – Usually Resident Population, publ. by National Records of Scotland. Web site http://www.scotlandscensus.gov.uk/ retrieved March 2016. See “Standard Outputs”, Table KS101SC, Area type: Civil Parish 1930 Markinch is east of Fife's administrative centre, Glenrothes and preceded Cupar as Fife's place of warranty and justice prior to the 13th century. History The earliest indications of human activity around Markinch are Balfarg henge and Balbirnie Stone Circle, in an area now incorporated into the new town of Glenrothes, but formerly part of Markinch Parish. They are said to date back to 3,000 BC from the Neolithic period.Fiet ''Old Markinch'' pp.3-4.Fife Council ''Glenrothes and Surrounding Villages ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Daily Telegraph
''The Daily Telegraph'', known online and elsewhere as ''The Telegraph'', is a national British daily broadsheet newspaper published in London by Telegraph Media Group and distributed across the United Kingdom and internationally. It was founded by Arthur B. Sleigh in 1855 as ''The Daily Telegraph & Courier''. Considered a newspaper of record over ''The Times'' in the UK in the years up to 1997, ''The Telegraph'' generally has a reputation for high-quality journalism, and has been described as being "one of the world's great titles". The paper's motto, "Was, is, and will be", appears in the editorial pages and has featured in every edition of the newspaper since 19 April 1858. The paper had a circulation of 363,183 in December 2018, descending further until it withdrew from newspaper circulation audits in 2019, having declined almost 80%, from 1.4 million in 1980.United Newspapers PLC and Fleet Holdings PLC', Monopolies and Mergers Commission (1985), pp. 5–16. Its si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beclometasone
Beclomethasone, also known as beclomethasone dipropionate, and sold under the brand name Qvar among others, is a corticosteroid, steroid medication. It is available as an inhaler, cream, pills, and nasal spray. The inhaled form is used in the long-term management of asthma. The cream may be used for dermatitis and psoriasis. The pills have been used to treat ulcerative colitis. The nasal spray is used to treat allergic rhinitis and nasal polyps. Common side effects with the inhaled form include Respiratory tract infection, respiratory infections, headaches, and throat inflammation. Serious side effects include an increased risk of infection, cataracts, Cushing's syndrome, and anaphylaxis, severe allergic reactions. Long-term use of the pill form may cause adrenal insufficiency. The pills may also cause mood or personality changes. The inhaled form is generally regarded as safe in pregnancy. Beclometasone is mainly a glucocorticoid. Beclomethasone dipropionate was first patented ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allen And Hanburys
Allen and Hanburys Ltd was a British pharmaceutical manufacturer, absorbed by Glaxo Laboratories in 1958. GlaxoSmithKline, its successor company, used the Allen and Hanburys name for the specialist respiratory division until beginning to phase it out in 2013. In 2021, the name was trademarked in the United States as part of the formation of Allen & Hanburys Inc., an American pharmaceutical and consumer products company focused on Pediatrics, Dermatology and Respiratory Care exclusively within the United States. History The business was founded in 1715 in Old Plough Court, Lombard Street, London, by Silvanus Bevan, a Welshman, apothecary and a Quaker. Bevan and his brother, Timothy, who became his partner and later succeeded him, were known for their just dealings and the integrity and quality of their drugs. The company grew into a respected pharmaceutical centre and had established a strong reputation with American doctors by the late 18th century. The West Indies was also an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glaxo Laboratories
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tenth largest pharmaceutical company and #294 on the 2022 ''Fortune'' Global 500, ranked behind other pharmaceutical companies China Resources, Sinopharm, Johnson & Johnson, Pfizer, Roche, AbbVie, Novartis, Bayer, and Merck. The company has a primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. , it had a market capitalisation of £70 billion, the eighth largest on the London Stock Exchange. It has a secondary listing on the New York Stock Exchange. The company developed the first malaria vaccine, RTS,S, which it said in 2014 it would make available for five percent above cost. Legacy products developed at GSK include several listed in the World Health Organization's List of Essential Medicines, such as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glasgow
Glasgow ( ; sco, Glesca or ; gd, Glaschu ) is the most populous city in Scotland and the fourth-most populous city in the United Kingdom, as well as being the 27th largest city by population in Europe. In 2020, it had an estimated population of 635,640. Straddling the border between historic Lanarkshire and Renfrewshire, the city now forms the Glasgow City Council area, one of the 32 council areas of Scotland, and is governed by Glasgow City Council. It is situated on the River Clyde in the country's West Central Lowlands. Glasgow has the largest economy in Scotland and the third-highest GDP per capita of any city in the UK. Glasgow's major cultural institutions – the Burrell Collection, Kelvingrove Art Gallery and Museum, the Royal Conservatoire of Scotland, the Royal Scottish National Orchestra, Scottish Ballet and Scottish Opera – enjoy international reputations. The city was the European Capital of Culture in 1990 and is notable for its architecture, cult ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacist
A pharmacist, also known as a chemist (Commonwealth English) or a druggist (North American and, archaically, Commonwealth English), is a healthcare professional who prepares, controls and distributes medicines and provides advice and instructions on the correct and safe use of medicines to achieve maximum benefit, minimal side effects and to avoid drug interactions. They also serve as primary care providers in the community. Pharmacists undergo university or graduate-level education to understand the biochemical mechanisms and actions of drugs, drug uses, therapeutic roles, side effects, potential drug interactions, and monitoring parameters. This is mated to anatomy, physiology, and pathophysiology. Pharmacists interpret and communicate this specialized knowledge to patients, physicians, and other health care providers. Among other licensing requirements, different countries require pharmacists to hold either a Bachelor of Pharmacy, Master of Pharmacy, or Doctor of Pharmacy d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edinburgh University
The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1582 and officially opened in 1583, it is one of Scotland's four ancient universities and the sixth-oldest university in continuous operation in the English-speaking world. The university played an important role in Edinburgh becoming a chief intellectual centre during the Scottish Enlightenment and contributed to the city being nicknamed the "Athens of the North." Edinburgh is ranked among the top universities in the United Kingdom and the world. Edinburgh is a member of several associations of research-intensive universities, including the Coimbra Group, League of European Research Universities, Russell Group, Una Europa, and Universitas 21. In the fiscal year ending 31 July 2021, it had a total income of £1.176 billion, of which £3 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Buckhaven High School
Buckhaven High School was a six-year co-educational non-denominational comprehensive school in Buckhaven, Fife, Scotland. In the past, Buckhaven was Levenmouth's high school for pupils who passed their qualifying exam. The school's motto was ''Perseverando''. The school's origins dated back to the 1860s and for many years it occupied a site in College Street, Buckhaven. The most recent building was in use from 1957 until 2016, and in 1976 an extension was completed. The catchments for the school were Buckhaven Primary, Methilhill Primary, East Wemyss Primary, Coaltown of Wemyss Primary, Parkhill Primary, Kirkton of Largo Primary and Kennoway Primary. They also received pupils from out with the catchments who submitted placing requests. Merger In June 2012 Fife Council proposed that the school should merge with neighbouring Kirkland High School and Community College to create Levenmouth Academy. The plans were approved in April 2014 and the new school opened to pupils on 17 Augu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scotland
Scotland (, ) is a country that is part of the United Kingdom. Covering the northern third of the island of Great Britain, mainland Scotland has a border with England to the southeast and is otherwise surrounded by the Atlantic Ocean to the north and west, the North Sea to the northeast and east, and the Irish Sea to the south. It also contains more than 790 islands, principally in the archipelagos of the Hebrides and the Northern Isles. Most of the population, including the capital Edinburgh, is concentrated in the Central Belt—the plain between the Scottish Highlands and the Southern Uplands—in the Scottish Lowlands. Scotland is divided into 32 administrative subdivisions or local authorities, known as council areas. Glasgow City is the largest council area in terms of population, with Highland being the largest in terms of area. Limited self-governing power, covering matters such as education, social services and roads and transportation, is devolved from the Scott ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asthma
Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise. Asthma is thought to be caused by a combination of genetic and environmental factors. Environmental factors include exposure to air pollution and allergens. Other potential triggers include medications such as aspirin and beta blockers. Diagnosis is usually based on the pattern of symptoms, response to therapy over time, and spirometry lung function testing. Asthma is classified according to the frequency of symptoms, forced expiratory volume in one second (FEV1), and peak expiratory flow rate. It may also be classified as atopic or non-atopic, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medicinal Chemist
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). Medicinal chemistry is a highly interdisciplinary science combining organic chemistry with biochemistry, computational chemistry, pharmacology, molecular biology, statistics, and physical chemistry. Compounds used as medicines are most often organic compounds, which are often divided into the broad classes of small organic molecules (e.g., atorvastatin, fluticasone, clopidogrel) and "biologics" (infliximab, erythropoietin, insulin glargine), the latter of which are most often medicinal preparations of proteins (natural and recombinant antibodi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
