Collagen, Type V, Alpha 2
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Collagen, Type V, Alpha 2
Collagen alpha-2(V) chain is a protein that in humans is encoded by the ''COL5A2'' gene. This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, classical type, formerly known as types I and II. See also * Type-V collagen *TSR1 RTS 1 (french: RTS Un) is a Swiss public television channel owned by RTS Radio Télévision Suisse, the public broadcaster for the Romand people. History Launched on 1 May 1954 to succeed Télé Genà ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ...
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Type-V Collagen
Type V collagen is a form of fibrillar collagen associated with classical Ehlers-Danlos syndrome. It is found within the dermal/epidermal junction, placental tissues, as well as in association with tissues containing type I collagen. Autoimmunity against type V collagen is associated with lung transplant failure. Genes * COL5A1, COL5A2, COL5A3 Collagen alpha-3(V) chain is a protein that in humans is encoded by the ''COL5A3'' gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' ... References External links * Collagens {{protein-stub ...
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TSR1
RTS 1 (french: RTS Un) is a Swiss public television channel owned by RTS Radio Télévision Suisse, the public broadcaster for the Romand people. History Launched on 1 May 1954 to succeed Télé Genève, RTS Un is the first channel of the two Swiss French networks of television group RTS (the other being RTS Deux). In 1968 the channel first aired programmes in colour. RTS took part in the creation of TV5 in 1984, and provides programmes for the international channel. Following the launch of TSR 2 in 1997, TSR renamed itself to TSR 1 and RTS Un in 2012. RTS Un is available in Aosta Valley, Italy, due to Italian self-government laws, and until the cessation of all digital terrestrial signals in Switzerland in 2019 could also be received in the border areas via spillover. Logos and identities File:TSR1 logo (1997-2006).png, TSR 1 logo from 1997 to 2006 File:Tsr1 logo.png, TSR 1 logo from 2006 to 2012 File:RTS un.svg, RTS Un logo from 2012 to 2015 File:RTS un HD.svg, RT ...
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