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China Kadoorie Biobank
The China Kadoorie Biobank is acquiring genomic data on half a million Chinese participants. In 2022 Genome-wide genotyping had been conducted for more than 100,000 participants using custom-designed Axiom® arrays. It collected questionnaire and physical data and blood samples on 510,000 men and women aged between 30 and 79 from 10 regions in China between 2004-2008 with the aim of investigating chronic diseases (e.g. heart attack, stroke, diabetes, and cancer). Participants have been linked to mortality registers and nationwide health systems and a sub-group of 25,000 are retested every few years. It is a joint venture by the University of Oxford’s Clinical Trial Service Unit & Epidemiological Studies Unit and the Chinese Academy of Medical Sciences. Research based on the biobank published by the American Thoracic Society in 2018 found that respiratory disease hospitalization or death were 36% higher among people who used wood or coal for cooking compared to those who used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial Service Unit
The Clinical Trial Service Unit (CTSU) is a medical research institute within the Nuffield Department of Population Health at Oxford University. It primarily conducts large scale clinical trials (phase III – Final Testing) and epidemiological studies of chronic diseases, especially cancer and vascular conditions. It is located in the Richard Doll Building (RDB) on the Old Road Campus, in Headington, Oxford, England. History The unit developed from a research team originally formed by Richard Doll. It was founded in 1975 and is led by the joint co-directors Richard Peto and Rory Collins. In 2013, there were approximately 250 staff working directly within the unit at the Richard Doll Building and many hundreds more at satellite centres around the world. Major projects Major clinical trials run by the CTSU include Isis, the Heart Protection Study, Search and Sharp. The unit has also played key roles in the Kadoorie Study of Chronic Disease and the UK Biobank UK Biobank is a l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chinese Academy Of Medical Sciences
Peking Union Medical College (), founded in 1906, is a selective public medical college based in Dongcheng, Beijing, China. It is a Chinese Ministry of Education Double First Class University Plan university. The school is tied to the Peking Union Medical College Hospital and has a joint 8-year clinical medicine science program with Tsinghua University. Peking Union Medical College students in the 8-year clinical medicine program could receive a Peking Union Medical College diploma and degree signed by both the Peking Union Medical College and Tsinghua presidents. It was merged with the Chinese Academy of Medical Sciences in 1957 and operates as one single institution with two names directly under the Ministry of Health, now the National Health Commission. It is the first medical school in China to introduce the 8-year M.D. program. History The Peking Union Medical College Hospital was founded in 1906. The American Board of Commissioners for Foreign Missions, the Board of F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Thoracic Society
The American Thoracic Society (ATS) is a nonprofit organization focused on improving care for pulmonary diseases, critical illnesses and sleep-related breathing disorders. It was established in 1905 as the American Sanatorium Association, and changed its name in 1938 to the American Trudeau Society. In 1960, it changed its name again to the American Thoracic Society. Originally the medical section of the American Lung Association, the Society became independently incorporated in 2000 as a 501 (c) (3) organization. Medical and scientific areas of interest Pulmonology, critical care, sleep medicine, infectious disease, pediatrics, allergy/immunology, thoracic surgery, behavioral science, environmental and occupational medicine, physiology, molecular biology, among others. Membership More than 15,000 physicians, research scientists, and nurses and other allied healthcare professionals (32 percent of whom work outside the United States). ATS Assemblies The interests of members ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart (journal)
''Heart'' is a biweekly peer-reviewed medical journal covering all areas of cardiovascular medicine and surgery. It is the official journal of the British Cardiovascular Society. It was established in 1939 as the ''British Heart Journal'' and is published by the BMJ Group. The name was changed from ''British Heart Journal'' to ''Heart'' in 1996 with the start of volume 75. The editor-in-chief is Catherine Otto (University of Washington). A sister journal, '' Open Heart'', was established in 2010 with the aim of covering cardiovascular research with less emphasis on novelty or priority. History In 2010, ''Heart'' established a sister journal, ''Heart Asia''. It was the official journal of the Asia Pacific Heart Association and aimed to focus on cardiovascular research in the Asia Pacific region. In 2019, the journal ceased publication. Abstracting and indexing The journal is abstracted and indexed by Index Medicus, Science Citation Index Expanded, EMBASE, and Scopus. According ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemorrhagic Stroke
A stroke is a disease, medical condition in which poor cerebral circulation, blood flow to the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemorrhagic, due to bleeding. Both cause parts of the brain to stop functioning properly. Signs and symptoms of a stroke may include an hemiplegia, inability to move or feel on one side of the body, receptive aphasia, problems understanding or expressive aphasia, speaking, dizziness, or Homonymous hemianopsia, loss of vision to one side. Signs and symptoms often appear soon after the stroke has occurred. If symptoms last less than one or two hours, the stroke is a transient ischemic attack (TIA), also called a mini-stroke. A subarachnoid hemorrhage, hemorrhagic stroke may also be associated with a thunderclap headache, severe headache. The symptoms of a stroke can be permanent. Long-term complications may include pneumonia and Urinary incontin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ischemic Heart Disease
Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of atherosclerotic plaque in the arteries of the heart. It is the most common of the cardiovascular diseases. Types include stable angina, unstable angina, myocardial infarction, and sudden cardiac death. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and improve with rest. Shortness of breath may also occur and sometimes no symptoms are present. In many cases, the first sign is a heart attack. Other complications include heart failure or an abnormal heartbeat. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biobank Organizations
A biobank is a type of biorepository that stores biological samples (usually human) for use in research. Biobanks have become an important resource in medical research, supporting many types of contemporary research like genomics and personalized medicine. Biobanks can give researchers access to data representing a large number of people. Samples in biobanks and the data derived from those samples can often be used by multiple researchers for cross purpose research studies. For example, many diseases are associated with single-nucleotide polymorphisms. Genome-wide association studies using data from tens or hundreds of thousands of individuals can identify these genetic associations as potential disease biomarkers. Many researchers struggled to acquire sufficient samples prior to the advent of biobanks. Biobanks have provoked questions on privacy, research ethics, and medical ethics. Viewpoints on what constitutes appropriate biobank ethics diverge. However, a consensus has bee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Databases
Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis. They contain information from research areas including genomics, proteomics, metabolomics, microarray gene expression, and phylogenetics. Information contained in biological databases includes gene function, structure, localization (both cellular and chromosomal), clinical effects of mutations as well as similarities of biological sequences and structures. Biological databases can be classified by the kind of data they collect (see below). Broadly, there are molecular databases (for sequences, molecules, etc.), functional databases (for physiology, enzyme activities, phenotypes, ecology etc), taxonomic databases (for species and other taxonomic ranks), images and other media, or specimens (for museum collections etc.) Databases are important tools in assisting scientists to analyze and explain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
