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Clinical Trial Service Unit
The Clinical Trial Service Unit (CTSU) is a medical research institute within the Nuffield Department of Population Health at Oxford University. It primarily conducts large scale clinical trials (phase III – Final Testing) and epidemiological studies of chronic diseases, especially cancer and vascular conditions. It is located in the Richard Doll Building (RDB) on the Old Road Campus, in Headington, Oxford, England. History The unit developed from a research team originally formed by Richard Doll. It was founded in 1975 and is led by the joint co-directors Richard Peto and Rory Collins. In 2013, there were approximately 250 staff working directly within the unit at the Richard Doll Building and many hundreds more at satellite centres around the world. Major projects Major clinical trials run by the CTSU include Isis, the Heart Protection Study, Search and Sharp. The unit has also played key roles in the Kadoorie Study of Chronic Disease and the UK Biobank UK Biobank is a l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Peto
Sir Richard Peto (born 14 May 1943) is an English statistician and epidemiologist who is Professor of Medical Statistics and Epidemiology at the University of Oxford, England. Education He attended Taunton's School in Southampton and subsequently studied the Natural Sciences Tripos at Trinity College, Cambridge followed by a Master of Science degree in Statistics at Imperial College London. Career and research His career has included collaborations with Richard Doll beginning at the Medical Research Council Statistical Research Unit in London. He set up the Clinical Trial Service Unit (CTSU) in Oxford in 1975 and is currently co-director. Peto's paradox is named after him. Awards and honours He was elected a Fellow of the Royal Society in 1989 for his contributions to the development of meta-analysis. He is a leading expert on deaths related to tobacco use. "When Sir Richard Peto began work with the late Richard Doll fifty years ago, the UK had the worst death rates from s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Institutes In Oxford
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Departments Of The University Of Oxford
The various academic faculties, departments, and institutes of the University of Oxford are organised into four divisions, each with its own Head and elected board. They are the Humanities Division; the Social Sciences Division; the Mathematical, Physical and Life Sciences Division; and the Medical Sciences Division. Humanities Division The Humanities Division has received considerable praise for its work at the forefront of digitising the Humanities. The Humanities Division has been physically expanding into the new Radcliffe Observatory Quarter in Oxford. The current Head of the Humanities Division is Professor Karen O'Brien. Professor Sally Shuttleworth was Head from 2006 to 2011, Professor Shearer West served as Head between August 2011 and 2015, and Chris Wickham until 2018. The Division contains the following faculties and departments: * Rothermere American Institute * Ruskin School of Art * Faculty of Classics * Faculty of English * Faculty of History * History of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial Organizations
Clinical may refer to: Healthcare * Of or about a clinic, a healthcare facility * Of or about the practice of medicine Other uses * ''Clinical'' (film), a 2017 American horror thriller See also * * * Clinical chemistry, the analysis of bodily fluids for diagnostic and therapeutic purposes * Clinical death, the cessation of blood circulation and breathing * Clinical formulation, a theoretically-based explanation of information obtained from clinical assessment * Clinical governance, a systematic approach to maintaining and improving the quality of patient care * Clinical linguistics, linguistics applied to speech-language pathology * Clinical psychology, the understanding, preventing, and relieving psychologically-based distress or dysfunction * Clinical research, to determine the safety and effectiveness of medications etc. * Clinical significance, the practical importance of a treatment effect * Clinical trial, experiments or observations done in clinical research * Clinical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Institutes Established In 1975
Research is " creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, discovery, interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemologies, which vary considerably both within and between humanities and sciences. There are several forms of research: scientific, humanities, artistic, econom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1975 Establishments In The United Kingdom
It was also declared the ''International Women's Year'' by the United Nations and the European Architectural Heritage Year by the Council of Europe. Events January * January 1 - Watergate scandal (United States): John N. Mitchell, H. R. Haldeman and John Ehrlichman are found guilty of the Watergate cover-up. * January 2 ** The Federal Rules of Evidence are approved by the United States Congress. ** Bangladesh revolutionary leader Siraj Sikder is killed by police while in custody. ** A bomb blast at Samastipur, Bihar, India, fatally wounds Lalit Narayan Mishra, Minister of Railways. * January 5 – Tasman Bridge disaster: The Tasman Bridge in Hobart, Tasmania, Australia, is struck by the bulk ore carrier , killing 12 people. * January 7 – OPEC agrees to raise crude oil prices by 10%. * January 10–February 9 – The flight of '' Soyuz 17'' with the crew of Georgy Grechko and Aleksei Gubarev aboard the '' Salyut 4'' space station. * January 15 – Alvor Agreeme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UK Biobank
UK Biobank is a large long-term biobank study in the United Kingdom (UK) which is investigating the respective contributions of genetic predisposition and environmental exposure (including nutrition, lifestyle, medications etc.) to the development of disease. It began in 2006. Based in Stockport, Greater Manchester, it is incorporated as a limited company and registered charity in England and Wales, and registered as a charity in Scotland. Design The study is following about 500,000 volunteers in the UK, enrolled at ages from 40 to 69. Initial enrollment took place over four years from 2006, and the volunteers will be followed for at least 30 years thereafter. Prospective participants were invited to visit an assessment centre, at which they completed an automated questionnaire and were interviewed about lifestyle, medical history and nutritional habits; basic variables such weight, height, blood pressure etc. were measured; and blood and urine samples were taken. These sam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart Protection Study
The Heart Protection Study was a randomized controlled trial run by the Clinical Trial Service Unit, and funded by the Medical Research Council (UK), Medical Research Council (MRC) and the British Heart Foundation (BHF) in the United Kingdom. It studied the use of the statin, cholesterol lowering drug, simvastatin 40 mg and vitamin supplementation (vitamin E, vitamin C and carotene, beta carotene) in people who were at risk of cardiovascular disease. It was led by Jane Armitage, an epidemiologist at the Clinical Trial Service Unit. Results An outline of the study protocol was published in 1999. Initial results were published in 2002, which indicated that vitamins made little difference in modifying cardiovascular risk, but that simvastatin could significantly reduce the risk of cardiovascular events. Further publications, from 2003 and 2004, were concerned with the efficacy of simvastatin in diabetes patients and preventing stroke. A 2005 paper analyses the cost-effectiveness o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rory Collins
Sir Rory Edwards Collins FMedSci FRS (born 3 January 1955) is a British physician who is Professor of Medicine and Epidemiology at the Clinical Trial Service Unit within the University of Oxford, the head of the Nuffield Department of Population Health and a Fellow of Green Templeton College, Oxford. His work has been in the establishment of large-scale epidemiological studies of the causes, prevention and treatment of heart attacks, other vascular disease, and cancer, while also being closely involved in developing approaches to the combination of results from related studies ("meta-analyses"). Education Collins was educated at Dulwich College and studied Medicine at St Thomas's Hospital Medical School, part of the University of London (1974-1980), and Statistics at George Washington University from 1976 to 1977 and the University of Oxford from 1982 to 1983. Career and research Since 1985, Collins has been co-director with Sir Richard Peto of the University of Oxford's Clin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Doll
Sir William Richard Shaboe Doll (28 October 1912 – 24 July 2005) was a British physician who became an epidemiologist in the mid-20th century and made important contributions to that discipline. He was a pioneer in research linking smoking to health problems. With Ernst Wynder, Bradford Hill and Evarts Graham, he was credited with being the first to prove that smoking increased the risk of :lung cancer and :heart disease. (German studies had suggested a link as early as the 1920s but were forgotten or ignored until the 1990s.) He also carried out pioneering work on the relationship between radiation and leukaemia as well as that between asbestos and lung cancer, and alcohol and breast cancer. On 28 June 2012, he was the subject of an episode of ''The New Elizabethans'', a series broadcast on BBC Radio Four to mark the Diamond Jubilee of Queen Elizabeth II, dealing with 60 public figures from her reign. Biography Doll was born at Hampton, Middlesex (now part of south-we ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuffield Department Of Population Health
The Nuffield Department of Population Health (NDPH) of Oxford University is located at the Old Road Campus in Headington, Oxford, England. It is one of the largest departments within Oxford University's Medical Sciences Division. The head of department is Professor Sir Rory Collins. History The Nuffield Department of Population Health was formed from the merger of ten research units in the Medical Sciences Division in 2013, the majority of which were in the Department of Public Health which ceased to exist. These centres were the Cancer Epidemiology Unit (CEU); Centre for Health, Law and Emerging Technologies (HeLEX); Centre on Population Approaches for Non Communicable Disease Prevention (CPNP); Clinical Trial Service Unit (CTSU); the Ethox Centre; Health Economics Research Centre (HERC); Health Services Research Unit (HSRU); Medical Careers Research Group (MCRG); Medical Research Council Population Health Research Unit (MRC PHRU); and the National Perinatal Epidemiology Un ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
