Caudovirales
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Caudovirales
''Caudovirales'' is an order of viruses known as the tailed bacteriophages (''cauda'' is Latin for "tail"). Under the Baltimore classification scheme, the ''Caudovirales'' are group I viruses as they have double stranded DNA (dsDNA) genomes, which can be anywhere from 18,000 base pairs to 500,000 base pairs in length. The virus particles have a distinct shape; each virion has an icosahedral head that contains the viral genome, and is attached to a flexible tail by a connector protein. The order encompasses a wide range of viruses, many containing genes of similar nucleotide sequence and function. However, some tailed bacteriophage genomes can vary quite significantly in nucleotide sequence, even among the same genus. Due to their characteristic structure and possession of potentially homologous genes, it is believed these bacteriophages possess a common origin. There are 14 families, 73 subfamilies, 927 genera, and 2,814 species in the order. This makes ''Caudovirales'' the ...
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Herelleviridae
''Herelleviridae'' is a family of bacterial viruses of the order ''Caudovirales'' infecting members of the phylum Firmicutes. The family has five subfamilies, 33 genera and 92 species. __TOC__ Etymology The family's name, ''Herelle'' is in honor of Félix d'Hérelle, a French-Canadian microbiologist A microbiologist (from Ancient Greek, Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of Microorganism, microscopic organisms such as bacteria, algae, f ..., the suffix ''-viridae'' is the standard suffix for virus families.Jakub Barylski ''et al.''Analysis of Spounaviruses as a Case Study for the Overdue Reclassification of Tailed Phages Systematic Biology, Volume 69, Issue 1, January 2020, Pages 110–123, doi:10.1093/sysbio/syz036. epub 25 May 2019 Taxonomy The following subfamilies and genera are assigned to ''Herelleviridae'' (-''virinae'' denotes subfamily and -''virus'' deno ...
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Bacteriophage Structure
A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have structures that are either simple or elaborate. Their genomes may encode as few as four genes (e.g. MS2) and as many as hundreds of genes. Phages replicate within the bacterium following the injection of their genome into its cytoplasm. Bacteriophages are among the most common and diverse entities in the biosphere. Bacteriophages are ubiquitous viruses, found wherever bacteria exist. It is estimated there are more than 1031 bacteriophages on the planet, more than every other organism on Earth, including bacteria, combined. Viruses are the most abundant biological entity in the water column of the world's oceans, and the second largest component of biomass ...
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Autographiviridae
''Autographiviridae'' is a family of viruses in the order ''Caudovirales''. Bacteria serve as natural hosts. There are 373 species in this family, assigned to 9 subfamilies and 133 genera. History Since the 1990s, the term "T7 supergroup" has been coined for the expanding group of bacteriophages related to coliphage T7, as members of the family ''Podoviridae''. Enterobacteriaceae phages SP6 and K1-5 were the first to be considered as an estranged subgroup of the "T7 supergroup". ''Pseudomonas'' phage phiKMV also shared commonalities at the genome organizational level. As such, based on the available morphological and proteomic data, this clade of viruses was established as a subfamily of the family ''Podoviridae''. The subfamily was later raised to the level of family in 2019. Etymology The name of this family, termed ''Autographiviridae'', refers to the “auto-graphein” or “self-transcribing” phages which encode their own (single subunit) RNA polymerase, a common charact ...
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Ackermannviridae
''Ackermannviridae'' is a family of viruses in the order ''Caudovirales''. Gammaproteobacteria in the phylum Pseudomonadota serve as natural hosts. There are 2 subfamilies, 10 genera, and 63 species in the family. Etymology The family's name, ''Ackermann'' is in honor of Hans-Wolfgang Ackermann (1936-2017), a German microbiologist, the suffix ''-viridae'' is the standard suffix for virus families.Hans-W. AckermannLife in science Bacteriophage. 2012 Oct 1; 2(4): 207. doi: 10.4161/bact.23159 . . A curriculum vitae. Taxonomy The following taxa are recognized (-''virinae'' denotes subfamily and -''virus'' denotes genus): * '' Aglimvirinae'' ** '' Agtrevirus'' ** '' Limestonevirus'' * '' Cvivirinae'' ** ''Kuttervirus'' ''incertae sedis ' () or ''problematica'' is a term used for a taxonomic group where its broader relationships are unknown or undefined. Alternatively, such groups are frequently referred to as "enigmatic taxa". In the system of open nomenclature, uncertainty ...
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Phage
A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have structures that are either simple or elaborate. Their genomes may encode as few as four genes (e.g. MS2) and as many as hundreds of genes. Phages replicate within the bacterium following the injection of their genome into its cytoplasm. Bacteriophages are among the most common and diverse entities in the biosphere. Bacteriophages are ubiquitous viruses, found wherever bacteria exist. It is estimated there are more than 1031 bacteriophages on the planet, more than every other organism on Earth, including bacteria, combined. Viruses are the most abundant biological entity in the water column of the world's oceans, and the second largest component of biomass ...
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Bacteriophage
A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have structures that are either simple or elaborate. Their genomes may encode as few as four genes (e.g. MS2) and as many as hundreds of genes. Phages replicate within the bacterium following the injection of their genome into its cytoplasm. Bacteriophages are among the most common and diverse entities in the biosphere. Bacteriophages are ubiquitous viruses, found wherever bacteria exist. It is estimated there are more than 1031 bacteriophages on the planet, more than every other organism on Earth, including bacteria, combined. Viruses are the most abundant biological entity in the water column of the world's oceans, and the second largest component of biom ...
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Baltimore Classification
Baltimore classification is a system used to classify viruses based on their manner of messenger RNA (mRNA) synthesis. By organizing viruses based on their manner of mRNA production, it is possible to study viruses that behave similarly as a distinct group. Seven Baltimore groups are described that take into consideration whether the viral genome is made of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), whether the genome is single- or double-stranded, and whether the sense of a single-stranded RNA genome is positive or negative. Baltimore classification also closely corresponds to the manner of replicating the genome, so Baltimore classification is useful for grouping viruses together for both transcription and replication. Certain subjects pertaining to viruses are associated with multiple, specific Baltimore groups, such as specific forms of translation of mRNA and the host range of different types of viruses. Structural characteristics such as the shape of the vir ...
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Myoviridae
''Myoviridae'' is a family of bacteriophages in the order ''Caudovirales''. Bacteria and archaea serve as natural hosts. There are 625 species in this family, assigned to eight subfamilies and 217 genera. Subdivisions The subfamily ''Tevenvirinae'' (synonym: ''Tequatrovirinae'') is named after its type species ''Enterobacteria phage T4''. Members of this subfamily are morphologically indistinguishable and have moderately elongated heads of about 110 nanometers (nm) in length, 114 nm long tails with a collar, base plates with short spikes and six long kinked tail fibers. The genera within this subfamily are divided on the basis of head morphology with the genus ''Tequatrovirus'' (Provisional name: ''T4virus'') having a head length of 137 nm and those in the genus ''Schizot4virus'' being 111 nm in length. Within the genera on the basis of protein homology the species have been divided into a number of groups. The subfamily ''Peduovirinae'' have virions with heads of 6 ...
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Podoviridae
''Podoviridae'' is a family of bacteriophage in the order ''Caudovirales'' often associated with T-7 like phages. There are 130 species in this family, assigned to 3 subfamilies and 52 genera. This family is characterized by having very short, noncontractile tails. Podoviradae are largely understudied and most new isolates are of the phicbkviruses genus, a group of giant viruses that appear to be Caulobacter specific. Structure Viruses in ''Podoviridae'' are non-enveloped, with icosahedral and head-tail geometries. The diameter is around 60 nm, and consists of 72 capsomers. The head protein has a molecular mass of ~38 kiloDaltons and is present in 460 copies per virion. There are 9 structural proteins. The tail is non-contractile and has 6 short subterminal fibers. It is thick and rod-shaped and built of stacked disks. The maximum length is ~17 nm. The double stranded DNA genome is linear, around 40-42kb in length, and encodes ~55 genes. The guanine + cytosine Cy ...
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Prohead
A prohead or procapsid is an immature viral capsid structure formed in the early stages of self-assembly of some bacteriophages, including the ''Caudovirales ''Caudovirales'' is an order of viruses known as the tailed bacteriophages (''cauda'' is Latin for "tail"). Under the Baltimore classification scheme, the ''Caudovirales'' are group I viruses as they have double stranded DNA (dsDNA) genomes, ...'' or tailed bacteriophages. Production and assembly of stable proheads is an essential precursor to bacteriophage genome packaging; this packaging activity can be replicated ''in vitro''. The prohead structure may take a different shape from the head of a mature virion, as seen with the prohead of Bacillus subtilis phage φ29. References Bacteriophages {{virus-stub ...
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Capsid
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the helical shape resembles the shape of a spring, taking the space of a cylinder but not being a cylinder itself. The capsid faces may consist of one or more ...
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Siphoviridae
''Siphoviridae'' is a family of double-stranded DNA viruses in the order ''Caudovirales''. Bacteria and archaea serve as natural hosts. There are 1,166 species in this family, assigned to 366 genera and 22 subfamilies. The characteristic structural features of this family are a nonenveloped head and noncontractile tail. Structure Viruses in ''Siphoviridae'' are non-enveloped, with icosahedral and head-tail geometries (morphotype B1) or a prolate capsid (morphotype B2), and T=7 symmetry. The diameter is around 60 nm. Members of this family are also characterized by their filamentous, cross-banded, noncontractile tails, usually with short terminal and subterminal fibers. Genomes are double stranded and linear, around 50 kb in length, containing about 70 genes. The guanine/cytosine content is usually around 52%. Life cycle Viral replication is cytoplasmic. Entry into the host cell is achieved by adsorption into the host cell. Replication follows the replicative transposition ...
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