Parvovirinae
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Parvovirinae
''Parvovirinae'' is a subfamily of viruses in the family ''Parvoviridae''. There are ten genera and 84 species assigned to this subfamily. Taxonomy The following 10 genera are recognized: *'' Amdoparvovirus'' *'' Artiparvovirus'' *'' Aveparvovirus'' *'' Bocaparvovirus'' *'' Copiparvovirus'' *''Dependoparvovirus'' *'' Erythroparvovirus'' *'' Loriparvovirus'' *''Protoparvovirus'' *''Tetraparvovirus Tetraparvovirus are a genus of viruses in the family ''Parvoviridae''. There are six recognized species: '' Chiropteran tetraparvovirus 1'', '' Primate tetraparvovirus 1'', '' Ungulate tetraparvovirus 1'', '' Ungulate tetraparvovirus 2'', '' Ungu ...'' References External links ICTV ''Parvovirinae'' {{Taxonbar, from=Q2055184 Parvoviruses Virus subfamilies ...
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Parvoviridae
Parvoviruses are a family of animal viruses that constitute the family ''Parvoviridae''. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the protein the viral capsid is made of. The coding portion of the genome is flanked by telomeres at each end that form into hairpin loops that are important during replication. Parvovirus virions are small compared to most viruses, at 23–28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface. Parvoviruses enter a host cell by endocytosis, travelling to the nucleus where they wait until the cell enters its replication stage. At that point, the genome is uncoated and the coding portion is replicated. Viral messenger RNA (mRNA) is then transcribed and translated, resulting in NS1 initiating replication. During replication, the hairpins repeatedly unfold, are replicated, and refold to chang ...
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Parvoviruses
Parvoviruses are a family of animal viruses that constitute the family ''Parvoviridae''. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the protein the viral capsid is made of. The coding portion of the genome is flanked by telomeres at each end that form into hairpin loops that are important during replication. Parvovirus virions are small compared to most viruses, at 23–28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface. Parvoviruses enter a host cell by endocytosis, travelling to the nucleus where they wait until the cell enters its replication stage. At that point, the genome is uncoated and the coding portion is replicated. Viral messenger RNA (mRNA) is then transcribed and translated, resulting in NS1 initiating replication. During replication, the hairpins repeatedly unfold, are replicated, and refold to chang ...
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Parvovirinae
''Parvovirinae'' is a subfamily of viruses in the family ''Parvoviridae''. There are ten genera and 84 species assigned to this subfamily. Taxonomy The following 10 genera are recognized: *'' Amdoparvovirus'' *'' Artiparvovirus'' *'' Aveparvovirus'' *'' Bocaparvovirus'' *'' Copiparvovirus'' *''Dependoparvovirus'' *'' Erythroparvovirus'' *'' Loriparvovirus'' *''Protoparvovirus'' *''Tetraparvovirus Tetraparvovirus are a genus of viruses in the family ''Parvoviridae''. There are six recognized species: '' Chiropteran tetraparvovirus 1'', '' Primate tetraparvovirus 1'', '' Ungulate tetraparvovirus 1'', '' Ungulate tetraparvovirus 2'', '' Ungu ...'' References External links ICTV ''Parvovirinae'' {{Taxonbar, from=Q2055184 Parvoviruses Virus subfamilies ...
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Amdoparvovirus
''Amdoparvovirus'' is a genus of viruses in the family ''Parvoviridae'' in the subfamily ''Parvovirinae''. Mustelids (minks, ferrets, and fox Foxes are small to medium-sized, omnivorous mammals belonging to several genera of the family Canidae. They have a flattened skull, upright, triangular ears, a pointed, slightly upturned snout, and a long bushy tail (or ''brush''). Twelve sp ...es), skunk, and raccoons serve as natural hosts. There are five species in this genus. Diseases associated with this genus include progressive disorder of immune system. Taxonomy The following five species are assigned to the genus: *'' Carnivore amdoparvovirus 1'' *'' Carnivore amdoparvovirus 2'' *'' Carnivore amdoparvovirus 3'' *'' Carnivore amdoparvovirus 4'' *'' Carnivore amdoparvovirus 5'' Structure Viruses in the genus ''Amdoparvovirus'' have non-enveloped protein particles with T=1 icosahedral symmetry. They are around 18 to 26 nm in diameter and contain a single linear singl ...
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Aveparvovirus
''Aveparvovirus'' is a genus of viruses, in the subfamily ''Parvovirinae ''Parvovirinae'' is a subfamily of viruses in the family ''Parvoviridae''. There are ten genera and 84 species assigned to this subfamily. Taxonomy The following 10 genera are recognized: *'' Amdoparvovirus'' *'' Artiparvovirus'' *'' Aveparvovi ...'' of the virus family '' Parvoviridae''. There are three species in this genus. Diseases associated with this genus include: enteric disease and malabsorption syndrome. Taxonomy The following three species are assigned to the genus: * ''Columbid aveparvovirus 1'' * ''Galliform aveparvovirus 1'' * ''Gruiform aveparvovirus 1'' Structure Viruses in ''Aveparvovirus'' are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, around 6kb in length. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, and is probably driven by cla ...
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Bocaparvovirus
''Bocaparvovirus'' is a genus of viruses in the subfamily ''Parvovirinae'' of the virus family ''Parvoviridae''. Humans, cattle, and dogs serve as natural hosts. There are 28 species in this genus. Diseases associated with this genus include, in humans, acute respiratory illness, and in cattle, diarrhea and mild respiratory symptoms. History Bocaviruses were first described in animals in the early 1960s. Genome Like the other members of this family, bocaparvoviruses have two open reading frames—ORF1 and 2. Unique among parvoviruses, the bocaparvoviruses contain a third open reading frame between non-structural and structural coding regions. This gene encodes a highly phosphorylated nonstructural protein (NP1). ORF1 encodes a nonstructural protein (NS1) that is involved in viral genome replication. ORF2 encodes the two capsid proteins—VP1 and VP2. Like other parvoviruses, the VP1 unique region contains a phospholipase A(2) motif with a conserved Histidine– Aspartic acid-X ...
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Copiparvovirus
''Copiparvovirus'' is a genus of viruses in subfamily ''Parvovirinae ''Parvovirinae'' is a subfamily of viruses in the family ''Parvoviridae''. There are ten genera and 84 species assigned to this subfamily. Taxonomy The following 10 genera are recognized: *'' Amdoparvovirus'' *'' Artiparvovirus'' *'' Aveparvovi ...'' of the virus family '' Parvoviridae''. Pigs and cows are known to serve as natural hosts. There are seven species in this genus. Taxonomy The following seven species are assigned to the genus: *'' Pinniped copiparvovirus 1'' *'' Ungulate copiparvovirus 1'' *'' Ungulate copiparvovirus 2'' *'' Ungulate copiparvovirus 3'' *'' Ungulate copiparvovirus 4'' *'' Ungulate copiparvovirus 5'' *'' Ungulate copiparvovirus 6'' Structure Viruses in genus ''Copiparvovirus'' are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, around 6kb in length. Life cycle Viral replication is nuclear. Entr ...
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Dependoparvovirus
''Dependoparvovirus'' (formerly ''Dependovirus'' or Adeno-associated virus group) is a genus in the subfamily ''Parvovirinae'' of the virus family ''Parvoviridae''; they are Group II viruses according to the Baltimore classification. Some dependoparvoviruses are also known as adeno-associated viruses because they cannot replicate productively in their host cell without the cell being coinfected by a helper virus such as an adenovirus, a herpesvirus, or a vaccinia virus. Species There are eleven recognized species: * ''Adeno-associated dependoparvovirus A'' * '' Adeno-associated dependoparvovirus B'' * ''Anseriform dependoparvovirus 1'' * '' Avian dependoparvovirus 1'' * '' Carnivore dependoparvovirus 1'' * '' Chiropteran dependoparvovirus 1'' * '' Pinniped dependoparvovirus 1'' * '' Rodent dependoparvovirus 1'' * '' Rodent dependoparvovirus 2'' * '' Squamate dependoparvovirus 1'' * '' Squamate dependoparvovirus 2'' Virology Dependoparvoviruses have an icosahedral shape, mea ...
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Erythroparvovirus
''Erythroparvovirus'' is a genus of viruses in subfamily ''Parvovirinae'' of the virus family ''Parvoviridae''. Primates serve as natural hosts. There are seven species in this genus. Diseases associated with this genus include fifth disease and skin lesions. Taxonomy The following seven species are assigned to the genus: *'' Pinniped erythroparvovirus 1'' *''Primate erythroparvovirus 1 Primate erythroparvovirus 1, generally referred to as B19 virus (B19V), parvovirus B19 or sometimes erythrovirus B19, is the first (and until 2005 the only) known human virus in the Family (biology), family ''Parvoviridae'', genus ''Erythroparvo ...'' *'' Primate erythroparvovirus 2'' *'' Primate erythroparvovirus 3'' *'' Primate erythroparvovirus 4'' *'' Rodent erythroparvovirus 1'' *'' Ungulate erythroparvovirus 1'' Structure Viruses in ''Erythroparvovirus'' are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, ...
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Protoparvovirus
''Protoparvovirus'' is a genus of viruses in the ''Parvovirinae'' subfamily of the virus family ''Parvoviridae''. Vertebrates serve as natural hosts. There are 15 species in the genus including ''Rodent protoparvovirus 1'' for which the exemplar virus is minute virus of mice (MVM). This genus also includes canine parvovirus (CPV), which causes gastrointestinal tract damage in puppies that is about 80% fatal, and porcine parvovirus (PPV), which is a major cause of fetal death and infertility in pigs. The genus divides phylogenetically into two branches, one that contains many founder members of the family, such as MVM, CPV and PPV, which have been studied in considerable detail, and a second branch occupied exclusively by predicted viruses whose coding sequences were identified recently in the wild using virus discovery approaches, but whose biology remains minimally explored. This second branch currently contains two species whose members infect humans, called ''Primate protoparvo ...
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Canine Parvovirus
Canine parvovirus (also referred to as CPV, CPV2, or parvo) is a contagious virus mainly affecting dogs. CPV is highly contagious and is spread from dog to dog by direct or indirect contact with their feces. Vaccines can prevent this infection, but mortality can reach 91% in untreated cases. Treatment often involves veterinary hospitalization. Canine parvovirus often infects other mammals including foxes, wolves, cats, and skunks. Felines (cats) are also susceptible to panleukopenia, a different strain of parvovirus. Signs Dogs that develop the disease show signs of the illness within three to ten days. The signs may include lethargy, vomiting, fever, and diarrhea (usually bloody). Generally, the first sign of CPV is lethargy. Secondary signs are loss of weight and appetite or diarrhea followed by vomiting. Diarrhea and vomiting result in dehydration that upsets the electrolyte balance and this may affect the dog critically. Secondary infections occur as a result of the weaken ...
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Tetraparvovirus
Tetraparvovirus are a genus of viruses in the family ''Parvoviridae''. There are six recognized species: '' Chiropteran tetraparvovirus 1'', '' Primate tetraparvovirus 1'', '' Ungulate tetraparvovirus 1'', '' Ungulate tetraparvovirus 2'', '' Ungulate tetraparvovirus 3'', and '' Ungulate tetraparvovirus 4''. History The first member of this genus was identified in 2001 in pig serum and designated Porcine parvovirus 2.Hijikata M, Abe K, Win KM, Shimizu YK, Keicho N, ''et al'' (2001) Identification of new parvovirus DNA sequence in swine sera from Myanmar. Jpn J. Infect. Dis 54: 244-245. The first human tetraparvovirus, PARV4, was described in 2005.Jones MS, Kapoor A, Lukashov VV, Simmonds P, Hecht F, ''et al'' (2005) New DNA viruses identified in patients with acute viral infection syndrome. J Virol 79: 8230–8236. These new viruses were recognised as being related to but distinct from the known parvoviruses. They were isolated from a group of patients who had engaged in high risk ...
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