Erythroparvovirus
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''Erythroparvovirus'' is a genus of
viruses A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...
in subfamily ''
Parvovirinae ''Parvovirinae'' is a subfamily of viruses in the family ''Parvoviridae''. There are ten genera and 84 species assigned to this subfamily. Taxonomy The following 10 genera are recognized: *'' Amdoparvovirus'' *'' Artiparvovirus'' *'' Aveparvovi ...
'' of the virus family ''
Parvoviridae Parvoviruses are a family of animal viruses that constitute the family ''Parvoviridae''. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the pr ...
''. Primates serve as natural hosts. There are seven species in this genus. Diseases associated with this genus include
fifth disease Erythema infectiosum, fifth disease, or slapped cheek syndrome is one of several possible manifestations of infection by parvovirus B19. Fifth disease typically presents as a rash and is more common in children. While parvovirus B19 can affect hu ...
and skin lesions.


Taxonomy

The following seven species are assigned to the genus: *'' Pinniped erythroparvovirus 1'' *''
Primate erythroparvovirus 1 Primate erythroparvovirus 1, generally referred to as B19 virus (B19V), parvovirus B19 or sometimes erythrovirus B19, is the first (and until 2005 the only) known human virus in the Family (biology), family ''Parvoviridae'', genus ''Erythroparvo ...
'' *'' Primate erythroparvovirus 2'' *'' Primate erythroparvovirus 3'' *'' Primate erythroparvovirus 4'' *'' Rodent erythroparvovirus 1'' *'' Ungulate erythroparvovirus 1''


Structure

Viruses in ''Erythroparvovirus'' are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, around 6kb in length.


Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. Dna templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear pore export. Primates serve as the natural host. Transmission routes are oral and respiratory.


References


External links


Viralzone: Erythroparvovirus

ICTV
{{Taxonbar, from=Q5396517 Parvovirinae Virus genera