Csaba Szabo (pharmacologist)
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Csaba Szabo (pharmacologist)
Csaba Szabo, a physician and pharmacologist, is the Head of the Pharmacology Section and President of the Department of Oncology, Microbiology and Immunology (OMI) of the University of Fribourg in Switzerland. The Public Library of Science Magazine, PLOS Biology, recognized Szabo in 2019 as one of the most cited researchers in the world. Early life Szabo was born in Győr, Hungary on July 12, 1967. He received his M.D. from the Semmelweis University Medical School in Budapest in 1992. From 1992 to 1994 he trained in pharmacology at the William Harvey Institute in London with Nobel Laureate Sir John Vane and received a Ph.D. in pharmacology. Szabo also holds a Ph.D. in physiology, and a Doctor of Sciences degree from the Hungarian University of Sciences. From 2018 he serves as the Chair of the Pharmacology Section at the University of Fribourg, Switzerland. Research Szabo's research investigates the biological roles of small diffusible, labile gaseous molecules (gasotransmit ...
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ...
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Hungarian Pharmacologists
Hungarian may refer to: * Hungary, a country in Central Europe * Kingdom of Hungary, state of Hungary, existing between 1000 and 1946 * Hungarians, ethnic groups in Hungary * Hungarian algorithm, a polynomial time algorithm for solving the assignment problem * Hungarian language Hungarian () is an Uralic language spoken in Hungary and parts of several neighbouring countries. It is the official language of Hungary and one of the 24 official languages of the European Union. Outside Hungary, it is also spoken by Hungarian ..., a Finno-Ugric language spoken in Hungary and all neighbouring countries * Hungarian notation, a naming convention in computer programming * Hungarian cuisine, the cuisine of Hungary and the Hungarians See also * * {{disambiguation Language and nationality disambiguation pages ...
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Hungarian Physicians
Hungarian may refer to: * Hungary, a country in Central Europe * Kingdom of Hungary, state of Hungary, existing between 1000 and 1946 * Hungarians, ethnic groups in Hungary * Hungarian algorithm, a polynomial time algorithm for solving the assignment problem * Hungarian language, a Finno-Ugric language spoken in Hungary and all neighbouring countries * Hungarian notation, a naming convention in computer programming * Hungarian cuisine Hungarian or Magyar cuisine is the cuisine characteristic of the nation of Hungary and its primary ethnic group, the Magyars. Traditional Hungarian dishes are primarily based on meats, seasonal vegetables, fruits, bread, and dairy products. ..., the cuisine of Hungary and the Hungarians See also * * {{disambiguation Language and nationality disambiguation pages ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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1967 Births
Events January * January 1 – Canada begins a year-long celebration of the 100th anniversary of Confederation, featuring the Expo 67 World's Fair. * January 5 ** Spain and Romania sign an agreement in Paris, establishing full consular and commercial relations (not diplomatic ones). ** Charlie Chaplin launches his last film, ''A Countess from Hong Kong'', in the UK. * January 6 – Vietnam War: United States Marine Corps, USMC and Army of the Republic of Vietnam, ARVN troops launch ''Operation Deckhouse Five'' in the Mekong Delta. * January 8 – Vietnam War: Operation Cedar Falls starts. * January 13 – A military coup occurs in Togo under the leadership of Étienne Eyadema. * January 14 – The Human Be-In takes place in Golden Gate Park, San Francisco; the event sets the stage for the Summer of Love. * January 15 ** Louis Leakey announces the discovery of pre-human fossils in Kenya; he names the species ''Proconsul nyanzae, Kenyapithecus africanus''. ** American footbal ...
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PLOS Biology
''PLOS Biology'' is a monthly peer-reviewed scientific journal covering all aspects of biology. Publication began on October 13, 2003. It is the first journal published by the Public Library of Science. The editor-in-chief is Nonia Pariente. In addition to research articles, the journal publishes magazine content aimed to be accessible to a broad audience. Article types in this section are essays, "unsolved mysteries", editorials, and synopses. Abstracting and indexing The journal is abstracted and indexed in: *Biological Abstracts *BIOSIS Previews *''Current Contents''/Agriculture, Biology & Environmental Sciences *''Current Contents''/Life Sciences *Chemical Abstracts Service * Embase *''Index Medicus''/MEDLINE/PubMed *Science Citation Index *Scopus *''The Zoological Record'' According to ''Journal Citation Reports'', the journal had a 2019 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clariv ...
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British Pharmacological Society
The British Pharmacological Society is the primary UK learned society for pharmacologists concerned with research into drugs and the way they work. Members work in academia, industry, regulatory agencies and the health services, and many are medically qualified. The Society covers the whole spectrum of pharmacology, including laboratory, clinical, and toxicological aspects. Clinical pharmacology is the medical speciality dedicated to promoting safe and effective use of medicines for patient benefit. Clinical pharmacologists work as consultants in the National Health Service and many hold prominent positions in UK universities. History The Society was founded in 1931, in Oxford, by a group of about 20 pharmacologists. They were brought together on the initiative of Professor James Andrew Gunn, by a letter signed by Gunn, H.H. Dale, and W.E. Dixon and sent to the heads of departments for teaching pharmacology and of institutions for pharmacological research in Great Britain, with p ...
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Cyanide
Cyanide is a naturally occurring, rapidly acting, toxic chemical that can exist in many different forms. In chemistry, a cyanide () is a chemical compound that contains a functional group. This group, known as the cyano group, consists of a carbon atom triple-bonded to a nitrogen atom. In inorganic cyanides, the cyanide group is present as the anion . Soluble salts such as sodium cyanide (NaCN) and potassium cyanide (KCN) are highly toxic. Hydrocyanic acid, also known as hydrogen cyanide, or HCN, is a highly volatile liquid that is produced on a large scale industrially. It is obtained by acidification of cyanide salts. Organic cyanides are usually called nitriles. In nitriles, the group is linked by a covalent bond to carbon. For example, in acetonitrile (), the cyanide group is bonded to methyl (). Although nitriles generally do not release cyanide ions, the cyanohydrins do and are thus rather toxic. Bonding The cyanide ion is isoelectronic with carbon monoxide a ...
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Genentech
Genentech, Inc., is an American biotechnology corporation headquartered in South San Francisco, California. It became an independent subsidiary of Roche in 2009. Genentech Research and Early Development operates as an independent center within Roche. Historically, the company is regarded as the world's first biotechnology company. As of July 2021, Genentech employed 13,539 people. History The company was founded in 1976 by venture capitalist Robert A. Swanson and biochemist Herbert Boyer. Boyer is considered to be a pioneer in the field of recombinant DNA technology. In 1973, Boyer and his colleague Stanley Norman Cohen demonstrated that restriction enzymes could be used as "scissors" to cut DNA fragments of interest from one source, to be ligated into a similarly cut plasmid vector. While Cohen returned to the laboratory in academia, Swanson contacted Boyer to found the company. Boyer worked with Arthur Riggs and Keiichi Itakura from the Beckman Research Institute, and the ...
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Down Syndrome Bill
The Down Syndrome Act 2022 is an Act of Parliament introduced as a private member's bill and sponsored by Conservative MP Liam Fox. It was described as "world leading" by MP Ian Paisley Jr and is intended to make legal provisions for people living with Down syndrome. It was introduced by Baroness Hollins in the House of Lords. Background In the United Kingdom, it is estimated that there are 40,000 people living with the condition. The bill recognises people with Downs syndrome as a specific minority group, and ensures their specific social care needs are met. It is the first such legislation in the world. Support The bill was supported by the Conservative Disability Group, Down's Syndrome Policy Group and actor Tommy Jessop. The bill had the following cross-party co-sponsors in the House of Commons: Ben Lake, Ian Paisley, Lisa Cameron, Mark Logan, Nick Fletcher, Layla Moran, Darren Jones, James Daly, Flick Drummond and Elliot Colburn. Passage On 26 November 2021, i ...
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Upregulate
In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus. The complementary process that involves increases of such components is called upregulation. An example of downregulation is the cellular decrease in the expression of a specific receptor in response to its increased activation by a molecule, such as a hormone or neurotransmitter, which reduces the cell's sensitivity to the molecule. This is an example of a locally acting (negative feedback) mechanism. An example of upregulation is the response of liver cells exposed to such xenobiotic molecules as dioxin. In this situation, the cells increase their production of cytochrome P450 enzymes, which in turn increases degradation of these dioxin molecules. Downregulation or upregulation of an RNA or protein may also arise by an epigenetic alteration. Such an epige ...
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