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Coulter Principle
A Coulter counter is an apparatus for counting and sizing particles suspended in electrolytes. The Coulter counter is the commercial term for the technique known as resistive pulse sensing or electrical zone sensing, the apparatus is based on The Coulter principle named after its inventor, Wallace H. Coulter. A typical Coulter counter has one or more microchannels that separate two chambers containing electrolyte solutions. As fluid-containing particles or cells are drawn through each microchannel, each particle causes a brief change to the electrical resistance of the liquid. The counter detects these changes in the electrical resistance. Coulter principle The ''Coulter principle'' states that particles pulled through an orifice, concurrent with an electric current, produce a change in impedance that is proportional to the volume of the particle traversing the orifice. This pulse in impedance originates from the displacement of electrolyte caused by the particle. The prin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Particle Transit Channel
In the Outline of physical science, physical sciences, a particle (or corpuscule in older texts) is a small wikt:local, localized physical body, object which can be described by several physical property, physical or chemical property, chemical properties, such as volume, density, or mass. They vary greatly in size or quantity, from subatomic particles like the electron, to microscopic scale, microscopic particles like atoms and molecules, to macroscopic scale, macroscopic particles like powder (substance), powders and other granular materials. Particles can also be used to create scientific models of even larger objects depending on their density, such as humans moving in a crowd or celestial bodies in motion (physics), motion. The term ''particle'' is rather general in meaning, and is refined as needed by various scientific fields. Anything that is composed of particles may be referred to as being particulate. However, the noun ''particulates, particulate'' is most frequently ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flow Cytometry
Flow cytometry (FC) is a technique used to detect and measure physical and chemical characteristics of a population of cells or particles. In this process, a sample containing cells or particles is suspended in a fluid and injected into the flow cytometer instrument. The sample is focused to ideally flow one cell at a time through a laser beam, where the light scattered is characteristic to the cells and their components. Cells are often labeled with fluorescent markers so light is absorbed and then emitted in a band of wavelengths. Tens of thousands of cells can be quickly examined and the data gathered are processed by a computer. Flow cytometry is routinely used in basic research, clinical practice, and clinical trials. Uses for flow cytometry include: * Cell counting * Cell sorting * Determining cell characteristics and function * Detecting microorganisms * Biomarker detection * Protein engineering detection * Diagnosis of health disorders such as blood cancers * Measuring ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microfluidics
Microfluidics refers to the behavior, precise control, and manipulation of fluids that are geometrically constrained to a small scale (typically sub-millimeter) at which surface forces dominate volumetric forces. It is a multidisciplinary field that involves engineering, physics, chemistry, biochemistry, nanotechnology, and biotechnology. It has practical applications in the design of systems that process low volumes of fluids to achieve multiplexing, automation, and high-throughput screening. Microfluidics emerged in the beginning of the 1980s and is used in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Typically, micro means one of the following features: * Small volumes (μL, nL, pL, fL) * Small size * Low energy consumption * Microdomain effects Typically microfluidic systems transport, mix, separate, or otherwise process fluids. Various applications rely on passive fluid control using capillary fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lab-on-a-chip
A lab-on-a-chip (LOC) is a device that integrates one or several laboratory functions on a single integrated circuit (commonly called a "chip") of only millimeters to a few square centimeters to achieve automation and high-throughput screening. LOCs can handle extremely small fluid volumes down to less than pico-liters. Lab-on-a-chip devices are a subset of microelectromechanical systems (MEMS) devices and sometimes called "micro total analysis systems" (µTAS). LOCs may use microfluidics, the physics, manipulation and study of minute amounts of fluids. However, strictly regarded "lab-on-a-chip" indicates generally the scaling of single or multiple lab processes down to chip-format, whereas "µTAS" is dedicated to the integration of the total sequence of lab processes to perform chemical analysis. The term "lab-on-a-chip" was introduced when it turned out that µTAS technologies were applicable for more than only analysis purposes. History After the invention of microtechnolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pulse Height Analyzer
A pulse-height analyzer (PHA) is an instrument that accepts electronic pulses of varying heights from particle and event detectors, digitizes the pulse heights, and saves the number of pulses of each height in registers or channels, thus recording a pulse-height spectrum or pulse-height distribution used for later pulse-height analysis. PHAs are used in nuclear- and elementary-particle physics research. A PHA is a specific modification to multichannel analyzers. A pulse-height analyzer is also integrated into particle counters or used as a discrete module to calibrate particle counters. See also * Nuclear electronics Nuclear electronics is a subfield of electronics concerned with the design and use of high-speed electronic systems for nuclear physics and elementary particle physics research, and for industrial and medical use. Essential elements of such systems ... Experimental particle physics {{nuclear-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Signal Processing
Signal processing is an electrical engineering subfield that focuses on analyzing, modifying and synthesizing ''signals'', such as audio signal processing, sound, image processing, images, and scientific measurements. Signal processing techniques are used to optimize transmissions, Data storage, digital storage efficiency, correcting distorted signals, subjective video quality and to also detect or pinpoint components of interest in a measured signal. History According to Alan V. Oppenheim and Ronald W. Schafer, the principles of signal processing can be found in the classical numerical analysis techniques of the 17th century. They further state that the digital refinement of these techniques can be found in the digital control systems of the 1940s and 1950s. In 1948, Claude Shannon wrote the influential paper "A Mathematical Theory of Communication" which was published in the Bell System Technical Journal. The paper laid the groundwork for later development of information c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jewel Bearing
A jewel bearing is a plain bearing in which a metal spindle turns in a jewel-lined pivot hole. The hole is typically shaped like a torus and is slightly larger than the shaft diameter. The jewels are typically made from the mineral corundum, usually either synthetic sapphire or synthetic ruby. Jewel bearings are used in precision instruments where low friction, long life, and dimensional accuracy are important. Their largest use is in mechanical watches. History Jewel bearings were invented in 1704 for use in watches by Nicolas Fatio de Duillier, Peter Debaufre, and Jacob Debaufre, who received an English patent for the idea. Originally natural jewels were used, such as diamond, sapphire, ruby, and garnet. In 1902, Verneuil process, a process to make synthetic sapphire and ruby (crystalline aluminium oxide, also known as corundum) was invented by Auguste Verneuil, making jewelled bearings much cheaper. Today most jewelled bearings are synthetic ruby or sapphire. Historica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artifact (error)
In natural science and signal processing, an artifact or artefact is any error An error (from the Latin ''error'', meaning "wandering") is an action which is inaccurate or incorrect. In some usages, an error is synonymous with a mistake. The etymology derives from the Latin term 'errare', meaning 'to stray'. In statistics ... in the perception or representation of any information introduced by the involved equipment or technique(s). Computer science In ''computer science'', digital artifacts are anomalies introduced into digital signals as a result of digital signal processing. Microscopy In ''microscopy'', visual artifacts are sometimes introduced during the processing of samples into microscopic slide, slide form. Econometrics In ''econometrics'', which trades on computing relationships between related Variable (mathematics), variables, an artifact is a spurious finding, such as one based on either a faulty choice of variables or an over-extension of the computed relati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Model A COULTER COUNTER From Advertisement
A model is an informative representation of an object, person or system. The term originally denoted the plans of a building in late 16th-century English, and derived via French and Italian ultimately from Latin ''modulus'', a measure. Models can be divided into physical models (e.g. a model plane) and abstract models (e.g. mathematical expressions describing behavioural patterns). Abstract or conceptual models are central to philosophy of science, as almost every scientific theory effectively embeds some kind of model of the physical or human sphere. In commerce, "model" can refer to a specific design of a product as displayed in a catalogue or show room (e.g. Ford Model T), and by extension to the sold product itself. Types of models include: Physical model A physical model (most commonly referred to simply as a model but in this context distinguished from a conceptual model) is a smaller or larger physical copy of an object. The object being modelled may be small (for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Laboratory Automation
''SLAS Technology'' (Translating Life Sciences Innovation) is a peer-reviewed scientific journal published by the Society for Laboratory Automation and Screening in partnership with Elsevier . The editor-in-chief is Edward Kai-Hua Chow, Ph.D. (National University of Singapore). The journal explores ways in which scientists adapt advancements in technology for scientific exploration and experimentation, especially in life sciences research and development. This includes drug-delivery; diagnostics; biomedical and molecular imaging; personalized and precision medicine; high-throughput and other laboratory automation technologies; micro/nanotechnologies; analytical, separation and quantitative techniques; synthetic chemistry and biology; informatics (data analysis, statistics, bio, genomic and chemoinformatics); and more. The journal was published from 1996 through 2016 with the title ''Journal of Laboratory Automation''. Its name changed in 2017 to more accurately reflect the evolution ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Office Of Naval Research
The Office of Naval Research (ONR) is an organization within the United States Department of the Navy responsible for the science and technology programs of the U.S. Navy and Marine Corps. Established by Congress in 1946, its mission is to plan, foster, and encourage scientific research to maintain future naval power and preserve national security. It carries this out through funding and collaboration with schools, universities, government laboratories, nonprofit organizations, and for-profit organizations, and overseeing the Naval Research Laboratory, the corporate research laboratory for the Navy and Marine Corps. NRL conducts a broad program of scientific research, technology and advanced development. ONR Headquarters is in the Ballston neighborhood of Arlington, Virginia. ONR Global has offices overseas in Santiago, Sao Paulo, London, Prague, Singapore, and Tokyo. Overview ONR was authorized by an Act of Congress, Public Law 588, and subsequently approved by President ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atomic Bombings Of Hiroshima And Nagasaki
The United States detonated two atomic bombs over the Japanese cities of Hiroshima and Nagasaki on 6 and 9 August 1945, respectively. The two bombings killed between 129,000 and 226,000 people, most of whom were civilians, and remain the only use of nuclear weapons in armed conflict so far. In the final year of World War II, the Allies prepared for a costly invasion of the Japanese mainland. This undertaking was preceded by a conventional and firebombing campaign that devastated 64 Japanese cities. The war in the European theatre concluded when Germany surrendered on 8 May 1945, and the Allies turned their full attention to the Pacific War. By July 1945, the Allies' Manhattan Project had produced two types of atomic bombs: "Fat Man", a plutonium implosion-type nuclear weapon; and "Little Boy", an enriched uranium gun-type fission weapon. The 509th Composite Group of the United States Army Air Forces was trained and equipped with the specialized Silverplate version of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
