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Cold Laser
Low-level laser therapy (LLLT), cold laser therapy, or photobiomodulation (PBM) is a form of medicine that applies low-level (low- power) lasers or light-emitting diodes (LEDs) to the surface of the body. Whereas high-power lasers are used in laser medicine to cut or destroy tissue, it is claimed that application of low-power lasers relieves pain or stimulates and enhances cell function. The effects appear to be limited to a specified set of wavelengths, and administering LLLT below the dose range does not appear to be effective. Mechanism Research is ongoing about the mechanism of LLLT. The effects of LLLT appear to be limited to a specified set of wavelengths of laser, and administering LLLT below the dose range does not appear to be effective. Photochemical reactions are well known in biological research, and LLLT make use of the first law in photochemistry ( Grotthuss-Draper law): light must be absorbed by a chemical substance in order for a photochemical reaction to take ...
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Medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, o ...
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ...
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Light Emitting Diodes
A light-emitting diode (LED) is a semiconductor device that emits light when current flows through it. Electrons in the semiconductor recombine with electron holes, releasing energy in the form of photons. The color of the light (corresponding to the energy of the photons) is determined by the energy required for electrons to cross the band gap of the semiconductor. White light is obtained by using multiple semiconductors or a layer of light-emitting phosphor on the semiconductor device. Appearing as practical electronic components in 1962, the earliest LEDs emitted low-intensity infrared (IR) light. Infrared LEDs are used in remote-control circuits, such as those used with a wide variety of consumer electronics. The first visible-light LEDs were of low intensity and limited to red. Early LEDs were often used as indicator lamps, replacing small incandescent bulbs, and in seven-segment displays. Later developments produced LEDs available in visible, ultraviolet (UV) ...
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Budapest
Budapest (, ; ) is the capital and most populous city of Hungary. It is the ninth-largest city in the European Union by population within city limits and the second-largest city on the Danube river; the city has an estimated population of 1,752,286 over a land area of about . Budapest, which is both a city and county, forms the centre of the Budapest metropolitan area, which has an area of and a population of 3,303,786; it is a primate city, constituting 33% of the population of Hungary. The history of Budapest began when an early Celtic settlement transformed into the Roman town of Aquincum, the capital of Lower Pannonia. The Hungarians arrived in the territory in the late 9th century, but the area was pillaged by the Mongols in 1241–42. Re-established Buda became one of the centres of Renaissance humanist culture by the 15th century. The Battle of Mohács, in 1526, was followed by nearly 150 years of Ottoman rule. After the reconquest of Buda in 1686, the ...
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Semmelweis University
Ignaz Philipp Semmelweis (; hu, Semmelweis Ignác Fülöp ; 1 July 1818 – 13 August 1865) was a Hungarian physician and scientist, who was an early pioneer of antiseptic procedures. Described as the "saviour of mothers", he discovered that the incidence of puerperal fever (also known as "childbed fever") could be drastically reduced by requiring hand disinfection in obstetrical clinics. Puerperal fever was common in mid-19th-century hospitals and often fatal. He proposed the practice of washing hands with chlorinated lime solutions in 1847 while working in Vienna General Hospital's First Obstetrical Clinic, where doctors' wards had three times the mortality of midwives' wards. He published a book of his findings in ''Etiology, Concept and Prophylaxis of Childbed Fever''. Despite various publications of results where hand-washing reduced mortality to below 1%, Semmelweis's observations conflicted with the established scientific and medical opinions of the time and his idea ...
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Ulcer (dermatology)
An ulcer is a sore on the skin or a mucous membrane, accompanied by the disintegration of tissue. Ulcers can result in complete loss of the epidermis and often portions of the dermis and even subcutaneous fat. Ulcers are most common on the skin of the lower extremities and in the gastrointestinal tract. An ulcer that appears on the skin is often visible as an inflamed tissue with an area of reddened skin. A skin ulcer is often visible in the event of exposure to heat or cold, irritation, or a problem with blood circulation. They can also be caused due to a lack of mobility, which causes prolonged pressure on the tissues. This stress in the blood circulation is transformed to a skin ulcer, commonly known as bedsores or decubitus ulcers. Ulcers often become infected, and pus forms. Signs and symptoms Skin ulcers appear as open craters, often round, with layers of skin that have eroded. The skin around the ulcer may be red, swollen, and tender. Patients may feel pain on the skin ...
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Reproducibility
Reproducibility, also known as replicability and repeatability, is a major principle underpinning the scientific method. For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated. There are different kinds of replication but typically replication studies involve different researchers using the same methodology. Only after one or several such successful replications should a result be recognized as scientific knowledge. With a narrower scope, ''reproducibility'' has been introduced in computational sciences: Any results should be documented by making all data and code available in such a way that the computations can be executed again with identical results. In recent decades, there has been a rising concern that many published scientific results fail the test of reproducibility, evoking a r ...
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Helium–neon Laser
A helium–neon laser or He-Ne laser, is a type of gas laser whose high energetic medium gain medium consists of a mixture of 10:1 ratio of helium and neon at a total pressure of about 1 torr inside of a small electrical discharge. The best-known and most widely used He-Ne laser operates at a wavelength of 632.8 nm, in the red part of the visible spectrum. History of He-Ne laser development The first He-Ne lasers emitted infrared at 1150 nm, and were the first gas lasers and the first lasers with continuous wave output. However, a laser that operated at visible wavelengths was much more in demand, and a number of other neon transitions were investigated to identify ones in which a population inversion can be achieved. The 633 nm line was found to have the highest gain in the visible spectrum, making this the wavelength of choice for most He-Ne lasers. However, other visible and infrared stimulated-emission wavelengths are possible, and by using mirror coatings ...
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Ruby Laser
A ruby laser is a solid-state laser that uses a synthetic ruby crystal as its gain medium. The first working laser was a ruby laser made by Theodore H. "Ted" Maiman at Hughes Research Laboratories on May 16, 1960. Ruby lasers produce pulses of coherent visible light at a wavelength of 694.3  nm, which is a deep red color. Typical ruby laser pulse lengths are on the order of a millisecond. Design A ruby laser most often consists of a ruby rod that must be pumped with very high energy, usually from a flashtube, to achieve a population inversion. The rod is often placed between two mirrors, forming an optical cavity, which oscillate the light produced by the ruby's fluorescence, causing stimulated emission. Ruby is one of the few solid state lasers that produce light in the visible range of the spectrum, lasing at 694.3 nanometers, in a deep red color, with a very narrow linewidth of 0.53 nm.''Principles of Lasers'' By Orazio Svelto – Plenum Press 1976 Page 367–370. ...
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Endre Mester
Hungarian physician Endre Mester (1903–1984) was a pioneer of laser medicine, especially the use of low level laser therapy (LLLT). In 1967, only a few years after the first working laser was invented, he started his experiments with the effects of lasers on skin cancer. He is credited as the discoverer of positive biological effects of low power lasers, which have been advocated as alternative medicine for use in wound healing, smoking cessation, tuberculosis, temporomandibular joint disorders, and musculoskeletal conditions such as carpal tunnel syndrome, fibromyalgia, osteoarthritis, and rheumatoid arthritis. LLLT devices are popular and may bring about temporary relief of some types of pain, but conventional medical authorities have found no reason to believe that they influence the course of any ailment or are more effective for pain control than other forms of heat delivery. Biography Early life Endre Mester was born on November 20, 1903 in Budapest, Hungary. He studied m ...
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Evidence-Based Veterinary Medicine Association
The Evidence-Based Veterinary Medicine Association (EBVMA) is an international, non-profit (501(c)3) professional organization founded with the mission of better organizing the emerging veterinary research, training, and practice of evidence-based veterinary medicine (EBVM) — the formal strategy to integrate the best critically designed and statistically evaluated research available combined with clinical expertise as well as the unique needs or wishes of each client in clinical practice. EBVM draws from and parallels the evidence-based medicine movement in human medicine. The EBVMA website asserts: Evidence-based veterinary medicine is the formal strategy to integrate the best research evidence available combined with clinical expertise as well as the unique needs or wishes of each client in clinical practice. Much of this is based on results from research studies that have been critically-designed and statistically evaluated. The EBVMA is based in Ridgeland, Mississippi, USA ...
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Tendinopathy
Tendinopathy, a type of tendon disorder that results in pain, swelling, and impaired function. The pain is typically worse with movement. It most commonly occurs around the shoulder ( rotator cuff tendinitis, biceps tendinitis), elbow (tennis elbow, golfer's elbow), wrist, hip, knee ( jumper's knee, popliteus tendinopathy), or ankle ( Achilles tendinitis). Causes may include an injury or repetitive activities. Less common causes include infection, arthritis, gout, thyroid disease, diabetes and the use of quinolone antibiotic medicines. Groups at risk include people who do manual labor, musicians, and athletes. Diagnosis is typically based on symptoms, examination, and occasionally medical imaging. A few weeks following an injury little inflammation remains, with the underlying problem related to weak or disrupted tendon fibrils. Treatment may include rest, NSAIDs, splinting, and physiotherapy. Less commonly steroid injections or surgery may be done. About 80% of patients r ...
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