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Cocculus Carolinus
''Cocculus carolinus'', commonly called the Carolina coralbead, or snailseed, or Margil's Vine, is a perennial vine of the moonseed family (Cocculus). It is native to North America, where it is found in Mexico and in several states in the United States from the Southeast to the Midwest. The species' common name derives from the appearance of its small, rounded red fruits, and the rough half-moon shape of its seeds. Description ''Cocculus carolinus'' is a climbing vine reaching 5 meters or more. It produces ovate or triangle-shaped leaves. The male and female flowers are small and green, appearing on different plants. The bright red fruit, a drupe, appears from June to August. It reaches 8 mm in size. Each fruit has a single seed that resembles a small snail shell, protected by the hard endocarp or the inner section of the ovary wall.
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Cocculus
''Cocculus'' is a genus of 11 species of woody vines and shrubs, native to warm temperate to tropical regions of North America, Asia and Africa. The common name moonseed is also used for the closely related genus '' Menispermum''. Selected species *''Cocculus carolinus'' ( L.) DC. – red-berried moonseed or Carolina moonseed (southeastern United States) *''Cocculus diversifolius'' DC. – correhuela (southern Texas, southern Arizona and northern Mexico) *''Cocculus hirsutus'' (L.) Diels (tropical Africa east to India and Nepal) *''Cocculus laurifolius'' DC. – laurel-leaved snail tree (Himalayas east to Japan) *''Cocculus orbiculatus'' (L.) DC. – queen coralbead (India east to Java) *''Cocculus sarmentosus'' ( Lour.) Diels (Taiwan) Formerly placed here *'' Jateorhiza palmata'' (Lam.) Miers (as ''C. palmatus'' (Lam.) DC.) *''Pericampylus glaucus'' (Lam.) Merr. (as ''C. incanus'' Colebr.) *'' Sinomenium acutum'' (Thunb.) Rehder & E.H.Wilson (as ''C. diversi ...
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Quercitol
5-Deoxyinositol (quercitol) is a cyclitol. It can be found in wines aged in oak wood barrels. It can also be found in '' Quercus'' sp. (oaks) and in '' Gymnema sylvestre''. It is different from , a synonym of quercetin. Biosynthesis The proposed biosynthesis of 5-deoxyinositol begins with the conversion of D-glucose to myo-inositol. In this pathway, D-glucose is phosphorylated to form D-glucose-6-phosphate. The NAD+ Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an aden ... dependent enzyme inositol 1-phosphate synthase (I1PS) then catalyzes the subsequent oxidation, enolization, aldol cyclization, and reduction of D-glucose 6-phosphate to form myo-inositol 1-phosphate. Hydrolysis of the phosphate group on this molecule gives myo-inositol. Myo-inositol can then be converted into 5-de ...
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Antonio Margil
Antonio Margil, OFM (18 August 1657 – 6 August 1726) was a Spanish Franciscan missionary in North and Central America. Life Margil entered the Franciscan Order in his Native city of Valencia, Spain on 22 April 1673. After his ordination to the priesthood, he volunteered for the Native American missions and arrived at Vera Cruz on 6 June 1683. He was stationed at the missionary college of Santa Cruz, Querétaro, but was generally engaged in reaching missions in Yucatan, Costa Rica, Nicaragua, and especially in Guatemala. He always walked barefooted, without sandals, fasted every day in the year, never used meat or fish, and applied the discipline and other instruments of penance to himself unmercifully. He slept very little but passed in prayer the greater part of the night, as well as the time allotted for the ''siesta''. On 25 June 1706, Margil was appointed the first guardian of the newly erected missionary college of Guadalupe, Zacatecas. In 1716 he led a band of three ...
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Palmatine
Palmatine is a protoberberine alkaloid found in several plants including ''Phellodendron amurense'', ''Coptis Chinensis'' (Rhizoma coptidis, chinese goldthread) and '' Corydalis yanhusuo'', ''Tinospora cordifolia'' (gurjo, heart-leaved moonseed), ''Tinospora sagittata'', ''Phellodendron amurense'' (amur cork tree), '' Stephania yunnanensis.'' It is the major component of the protoberberine extract from ''Enantia chlorantha''. It has been studied for its potential use in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases. This compound also has weak ''in vitro'' activity against flavivirus. Pharmacology Neuroprotective activity Palmatine can be used to treat Alzheimer’s disease, mainly by inhibiting the activity of acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and neuraminidase-1 (NA-1). It was found, that the positively charged nitrogen on palmatine binds in the gorge of active sire of AChE. Research show that palma ...
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Magnoflorine
''(S)-''Magnoflorine is a quaternary benzylisoquinoline alkaloid (BIA) of the aporphine structural subgroup which has been isolated from various species of the family Menispermaceae, such as ''Pachygone ovata,'' '' Sinomenium acutum,'' and ''Cissampelos pareira.''   It was identified among the verified anti-inflammatory components in an extract of ''Sinomenii caulis'' and has been proposed to have other potential physiological effects, such as sedative and anxiolytic, reduction of erythrocyte hemolysis, antifungal activity, improvement of LPS-induced acute lung injury, and protection against muscle atrophy. Furthermore, magnoflorine has been identified to be an inhibitor of NF-κB activation and to be an agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ... at the β2 -adren ...
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Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ...
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Lactone
Lactones are cyclic carboxylic esters, containing a 1-oxacycloalkan-2-one structure (), or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. Lactones are formed by intramolecular esterification of the corresponding hydroxycarboxylic acids, which takes place spontaneously when the ring that is formed is five- or six-membered. Lactones with three- or four-membered rings (α-lactones and β-lactones) are very reactive, making their isolation difficult. Special methods are normally required for the laboratory synthesis of small-ring lactones as well as those that contain rings larger than six-membered. Nomenclature Lactones are usually named according to the precursor acid molecule (''aceto'' = 2 carbon atoms, ''propio'' = 3, ''butyro'' = 4, ''valero'' = 5, ''capro'' = 6, etc.), with a ''-lactone'' suffix and a Greek letter prefix that specifies the number of carbon atoms in the heterocycle — that is, the distance between the relevant -OH ...
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Viburnitol
5-Deoxyinositol (quercitol) is a cyclitol. It can be found in wines aged in oak wood barrels. It can also be found in '' Quercus'' sp. (oaks) and in '' Gymnema sylvestre''. It is different from , a synonym of quercetin. Biosynthesis The proposed biosynthesis of 5-deoxyinositol begins with the conversion of D-glucose to myo-inositol. In this pathway, D-glucose is phosphorylated to form D-glucose-6-phosphate. The NAD+ Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an aden ... dependent enzyme inositol 1-phosphate synthase (I1PS) then catalyzes the subsequent oxidation, enolization, aldol cyclization, and reduction of D-glucose 6-phosphate to form myo-inositol 1-phosphate. Hydrolysis of the phosphate group on this molecule gives myo-inositol. Myo-inositol can then be converted into 5-de ...
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Cyclitol
In organic chemistry, a cyclitol is a cycloalkane containing at least three hydroxyl, each attached to a different ring carbon atom. The general formula for an unsubstituted cyclitol is or where 3 ≤ ''x'' ≤ ''n''. The name is also used for compounds that can be viewed as result of substituting various functional groups for the hydrogen atoms in such a molecule, as well as similar molecules with one or more double bonds in the ring. Cyclitols and their derivatives are some of the compatible solutes which are formed in a plant as a response to salt or water stress. Some cyclitols (e.g. quinic or shikimic acid) are parts of hydrolysable tannins. Isomerism and nomenclature Unsubstituted cyclitols with the same ring size and number of hydroxyls may exist in several structural isomers, depending on the position of the hydroxyls along the ring. For example, cyclohexanetriol exists in three distinct isomers (1,2,3-, 1,2,4-, and 1,3,5-). Furthermore, the hydrogen and the hydroxyl ...
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Mexico
Mexico (Spanish: México), officially the United Mexican States, is a country in the southern portion of North America. It is bordered to the north by the United States; to the south and west by the Pacific Ocean; to the southeast by Guatemala, Belize, and the Caribbean Sea; and to the east by the Gulf of Mexico. Mexico covers ,Mexico
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making it the world's 13th-largest country by are ...
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