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Cinchona Mission
The Cinchona Missions (1942-1945) were a series of expeditions led by the United States to find natural sources of quinine in South America during World War II. Background Bark of species from the genus ''Cinchona'' produces the alkaloid quinine, a potent anti-malarial treatment. Although originally native to South America, cinchona plantations were established in India, Ceylon, and the Dutch East Indies during the 19th century. By 1913, 95 percent of quinine production was controlled by the Dutch through large plantations on Java. With the outbreak of World War II, a supply of quinine was essential for successful military operations. In 1942, the Japanese occupation of the Dutch East Indies cut off the supply of quinine to the allies. Recognizing the need for a new source of quinine, a program was established by the United States Board of Economic Warfare under the operation of the Defense Supplies Corporation (DSC). Professor William C. Steere was brought on as assistant dire ...
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Quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. It can be taken by mouth or intravenously. Malaria resistance to quinine occurs in certain areas of the world. Quinine is also used as an ingredient in tonic water to impart a bitter taste. Common side effects include headache, ringing in the ears, vision issues, and sweating. More severe side effects include deafness, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy causes harm to the baby, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an alkaloid, a naturally occurring chemical compound. How it works as a medicin ...
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Costa Rica
Costa Rica (, ; ; literally "Rich Coast"), officially the Republic of Costa Rica ( es, República de Costa Rica), is a country in the Central American region of North America, bordered by Nicaragua to the north, the Caribbean Sea to the northeast, Panama to the southeast, the Pacific Ocean to the southwest, and Maritime boundary, maritime border with Ecuador to the south of Cocos Island. It has a population of around five million in a land area of . An estimated 333,980 people live in the capital and largest city, San José, Costa Rica, San José, with around two million people in the surrounding metropolitan area. The sovereign state is a Unitary state, unitary Presidential system, presidential Constitution of Costa Rica, constitutional republic. It has a long-standing and stable democracy and a highly educated workforce. The country spends roughly 6.9% of its budget (2016) on education, compared to a global average of 4.4%. Its economy, once heavily dependent on agricultu ...
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Joseph Andorfer Ewan
Joseph Andorfer Ewan (1909–1999) was a botanist, naturalist, and historian of botany and natural history. Biography Joseph Ewan grew up in Los Angeles and developed an early interest in the study of nature. At the age of eighteen, he published an ornithological report in '' The Condor''. He matriculated at UCLA and transferred to the University of California, Berkeley in 1933, graduating there with a B.A. in 1934. After graduating he remained at Berkeley until 1937 as a research assistant to Willis Jepson. In 1935 Ewan married a fellow botanical student, Ada Nesta Dunn (1908–2000), in Reno, Nevada. She often collaborated with him on their publications. He was from 1937 to 1944 an instructor at the University of Colorado, from 1944 to 1945 a botanist with the Foreign Economic Administration, from 1945 to 1946 an assistant curator at the Smithsonian Institution, and from 1946 to 1947 an associate botanist at the USDA's Bureau of Plant Industry. At Tulane University he became in ...
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William Brooks Drew
William Brooks Drew (December 11, 1908 – December 14, 1997) was an American botanist and professor. Career Drew received his B.S. degree from Massachusetts Agricultural College in 1930. He pursued an M.A. from Harvard University, which he received in 1931. He returned to Harvard and earned his Ph.D. in 1934. Drew started working as an Assistant at the Gray Herbarium while attending Harvard. In 1933, he signed on as a botanist for Louise A. Boyd's expedition of Greenland. At some point, Drew fell sick and Boyd was required to continue collecting plant specimens. He returned in 1934, taking professorships at the Cambridge School of Liberal Arts and at the American International College. In 1943, Drew took part in the Cinchona Missions in Ecuador to help gather quinine to treat malaria in the armed forces during WWII. In 1945, he was hired as an associate professor in the department of botany and plant pathology at Michigan State College. He was promoted to head of the departme ...
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Earl Lemley Core
Earl Lemley Core (January 20, 1902 – December 8, 1984) was a botanist and botanical educator, researcher, and author as well as a local West Virginia historian. He was founder of the Southern Appalachian Botanical Club and editor of its journal, '' Castanea'', for thirty-five years. He was a teacher and professor at West Virginia University (WVU) from 1928 to 1972. He served for four years on the Morgantown City Council, and served as mayor of Morgantown for two years. The Earl L. Core Arboretum at WVU was named in his honor in 1967. Clarkson, Roy B. and Jesse F. Clovis (1984), “Earl Lemley Core, 1902-1984”, ''Castanea'' 50(1): 1-6. Biography Youth and education Core was born on January 20, 1902, at Core, West Virginia, the son of Harry Michael and Clara Edna (''née'' Lemley) Core. He graduated from Morgantown High School and taught in rural schools from 1920 to 1923. He then attended WVU, earning a Bachelor of Arts in 1926 and a Master of Arts in 1928. He earned his Do ...
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La Paz
La Paz (), officially known as Nuestra Señora de La Paz (Spanish pronunciation: ), is the seat of government of the Bolivia, Plurinational State of Bolivia. With an estimated 816,044 residents as of 2020, La Paz is the List of Bolivian cities by population, third-most populous city in Bolivia. Its metropolitan area, which is formed by La Paz, El Alto, Achocalla Municipality, Achocalla, Viacha Municipality, Viacha, and Mecapaca Municipality, Mecapaca makes up the second most populous urban area in Bolivia, with a population of 2.0 million, after Santa Cruz de la Sierra with a population of 2.3 million. It is also the capital of the La Paz Department, Bolivia, La Paz Department. The city, in west-central Bolivia southeast of Lake Titicaca, is set in a canyon created by the Choqueyapu River. It is in a bowl-like depression, part of the Amazon basin, surrounded by the high mountains of the Altiplano. Overlooking the city is the towering, triple-peaked Illimani. Its peak ...
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Lima
Lima ( ; ), originally founded as Ciudad de Los Reyes (City of The Kings) is the capital and the largest city of Peru. It is located in the valleys of the Chillón River, Chillón, Rímac River, Rímac and Lurín Rivers, in the desert zone of the central coastal part of the country, overlooking the Pacific Ocean. Together with the seaside city of Callao, it forms a contiguous urban area known as the Lima Metropolitan Area. With a population of more than 9.7 million in its urban area and more than 10.7 million in its metropolitan area, Lima is one of the largest cities in the Americas. Lima was named by natives in the agricultural region known by native Peruvians as ''Limaq''. It became the capital and most important city in the Viceroyalty of Peru. Following the Peruvian War of Independence, it became the capital of the Republic of Peru (República del Perú). Around one-third of the national population now lives in its Lima Metropolitan Area, metropolitan area. The city of Li ...
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Quito
Quito (; qu, Kitu), formally San Francisco de Quito, is the capital and largest city of Ecuador, with an estimated population of 2.8 million in its urban area. It is also the capital of the province of Pichincha. Quito is located in a valley on the eastern slopes of Pichincha, an active stratovolcano in the Andes, at an elevation of , making it the second-highest capital city in the world.Contact Us
" TAME. Retrieved on 14 March 2010.
Quito is the political and cultural center of Ecuador as the country's major governmental, administrative, and cultural institutions are located within the city. The majority of transnational companies with a presence in Ecuador are headquartered there. It is also one of the country's two major industrial centers—the port city of

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Bogotá
Bogotá (, also , , ), officially Bogotá, Distrito Capital, abbreviated Bogotá, D.C., and formerly known as Santa Fe de Bogotá (; ) during the Spanish period and between 1991 and 2000, is the capital city of Colombia, and one of the largest cities in the world. The city is administered as the Capital District, as well as the capital of, though not part of, the surrounding department of Cundinamarca. Bogotá is a territorial entity of the first order, with the same administrative status as the departments of Colombia. It is the political, economic, administrative, and industrial center of the country. Bogotá was founded as the capital of the New Kingdom of Granada on 6 August 1538 by Spanish conquistador Gonzalo Jiménez de Quesada after a harsh expedition into the Andes conquering the Muisca, the indigenous inhabitants of the Altiplano. Santafé (its name after 1540) became the seat of the government of the Spanish Royal Audiencia of the New Kingdom of Granada (cre ...
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Rio Magdalena
The Magdalena River ( es, Río Magdalena, ; less commonly ) is the main river of Colombia, flowing northward about through the western half of the country. It takes its name from the biblical figure Mary Magdalene. It is navigable through much of its lower reaches, in spite of the shifting sand bars at the mouth of its delta, as far as Honda, at the downstream base of its rapids. It flows through the Magdalena River Valley. Its drainage basin covers a surface of , which is 24% of the country's area and where 66% of its population lives. Course The Magdalena River is the largest river system of the northern Andes, with a length of 1,612 km. Its headwaters are in the south of Colombia, where the Andean subranges Cordillera Central and Cordillera Oriental separate, in Huila Department. The river runs east then north in a great valley between the two cordilleras. It reaches the coastal plain at about nine degrees north, then runs west for about , then north again, reaching ...
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Cordillera Oriental (Colombia)
The Cordillera Oriental ( en, Eastern Ranges) is the widest of the three branches of the Colombian Andes. The range extends from south to north dividing from the Colombian Massif in Huila Department to Norte de Santander Department where it splits into the Serranía del Perijá and the Cordillera de Mérida in Venezuelan Andes. The highest peak is Ritacuba Blanco at in the Sierra Nevada del Cocuy. Geography The western part of the Cordillera Oriental belongs to the Magdalena River basin, while the eastern part includes the river basins of the Amazon River, Orinoco River, and Catatumbo River. Within it, the Altiplano Cundiboyacense and the Sierra Nevada del Cocuy (with the only snowy peaks in this mountain range) stand out. The mountain range contains the most páramos in the world. Protected areas * Cueva de los Guácharos * Chingaza National Natural Park * Yariguíes National Park * Sierra Nevada del Cocuy * Sumapaz Páramo * Tamá National Natural Park * Los Estoraques Uni ...
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Leslie Holdridge
Leslie Ransselaer Holdridge (September 29, 1907 – June 19, 1999) was an Americans, American botany, botanist and climatology, climatologist. He was the father of composer Lee Holdridge as well as the father of Leslie A. Holdridge, Lorena Holdridge, Marbella Holdridge, Marly Holdridge, Marisela Holdridge, Thania Holdridge, John Holdridge, Ida Holdridge, Reuseland Holdridge, Leythy J. Holdridge and youngest son Gregory Holdridge whom he fathered with Costa Rican Clara Luz Melendez. Career In his famous 1947 paper, he defined "life zones" using three indicators: # Mean annual biotemperature (average temperature, after data values below 0 °C or above 30 °C have been eliminated) # Total annual Precipitation (meteorology), precipitation # The ratio of mean annual potential evapotranspiration to mean total annual precipitation. Holdridge participated in the Cinchona Missions, a United States effort to search for natural sources of quinine during World War II.Steere, W. ...
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