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Cicatrizant
D03A Cicatrizants D03AA Cod-liver oil ointments D03AX Other cicatrizants :D03AX01 Cadexomer iodine :D03AX02 Dextranomer :D03AX03 Dexpanthenol :D03AX04 Calcium pantothenate :D03AX05 Hyaluronic acid :D03AX06 Becaplermin :D03AX09 Crilanomer :D03AX10 Enoxolone :D03AX11 Sodium chlorite (tetrachlorodecaoxide) :D03AX12 Trolamine :D03AX13 Betulae cortex :D03AX14 Centella asiatica herba :D03AX15 Trafermin :QD03AX90 Ketanserin D03B Enzymes D03BA Proteolytic enzymes :D03BA01 Trypsin :D03BA02 Clostridiopeptidase :D03BA03 Bromelain Bromelain is an enzyme extract derived from the stems of pineapples, although it exists in all parts of the fresh pineapple. The extract has a history of folk medicine use. As an ingredient, it is used in cosmetics, as a topical medication, and as ...s :D03BA52 Collagenase, combinations References {{Preparations for treatment of wounds and ulcers D03 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cicatrizant
D03A Cicatrizants D03AA Cod-liver oil ointments D03AX Other cicatrizants :D03AX01 Cadexomer iodine :D03AX02 Dextranomer :D03AX03 Dexpanthenol :D03AX04 Calcium pantothenate :D03AX05 Hyaluronic acid :D03AX06 Becaplermin :D03AX09 Crilanomer :D03AX10 Enoxolone :D03AX11 Sodium chlorite (tetrachlorodecaoxide) :D03AX12 Trolamine :D03AX13 Betulae cortex :D03AX14 Centella asiatica herba :D03AX15 Trafermin :QD03AX90 Ketanserin D03B Enzymes D03BA Proteolytic enzymes :D03BA01 Trypsin :D03BA02 Clostridiopeptidase :D03BA03 Bromelain Bromelain is an enzyme extract derived from the stems of pineapples, although it exists in all parts of the fresh pineapple. The extract has a history of folk medicine use. As an ingredient, it is used in cosmetics, as a topical medication, and as ...s :D03BA52 Collagenase, combinations References {{Preparations for treatment of wounds and ulcers D03 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trolamine
Triethanolamine, or TEA is a viscous organic compound that is both a tertiary amine and a triol. A triol is a molecule with three alcohol groups. Approximately 150,000 tonnes were produced in 1999. It is a colourless compound although samples may appear yellow because of impurities. Production Triethanolamine is produced from the reaction of ethylene oxide with aqueous ammonia, also produced are ethanolamine and diethanolamine. The ratio of the products can be controlled by changing the stoichiometry of the reactants. : Applications Triethanolamine is used primarily in making surfactants, such as for emulsifier. It is a common ingredient in formulations used for both industrial and consumer products. The triethanolamine neutralizes fatty acids, adjusts and buffers the pH, and solubilizes oils and other ingredients that are not completely soluble in water. Triethanolammonium salts in some cases are more soluble than salts of alkali metals that might be used otherwise, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bromelain (pharmacology)
Bromelain, a concentrate of proteolytic enzymes from the pineapple plant, is used in medicine. It is approved in the European Union for the debridement (removal of eschar, that is dead and damaged tissue) of severe burn wounds under the brand name Nexobrid. It was developed by MediWound. The medicine has been granted orphan drug status by the European Medicines Agency (EMA). In other contexts, bromelain has been researched for possible anti-inflammatory effects in treating a range of conditions or diseases, but results of these studies are mixed and regarded as preliminary. In December 2022, anacaulase-bcdb (Nexobrid) was approved for medical use in the United States. Medical uses In the United States, anacaulase gel is indicated for eschar removal in adults with deep partial thickness and/or full thickness thermal burns. The medication is approved for burns of degrees IIb, i.e. deep partial skin thickness burns, to III, i.e. full thickness burns, and has been shown to sign ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clostridiopeptidase
Clostripain (, ''clostridiopeptidase B'', ''clostridium histolyticum proteinase B'', ''alpha-clostridipain'', ''clostridiopeptidase'', ''Endoproteinase Arg-C'') is a proteinase that cleaves proteins on the carboxyl peptide bond of arginine. It was isolated from '' Clostridium histolyticum''. The isoelectric point of the enzyme is 4.8-4.9 (at 8 °C), and optimum pH is 7.4~7.8 (against α-benzoyl-arginine ethyl ester). The composition of the enzyme is indicated to be of two chains of relative molecular mass 45,000 and 12,500. See also * Benzoyl In organic chemistry, benzoyl (, ) is the functional group with the formula C6H5CO-. It can be viewed as benzaldehyde missing one hydrogen. The term "benzoyl" should not be confused with benzyl, which has the formula C6H5CH2. The benzoyl grou ... * Ethyl ester References External links * * EC 3.4.22 Post-translational modification {{hydrolase-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trypsin
Trypsin is an enzyme in the first section of the small intestine that starts the digestion of protein molecules by cutting these long chains of amino acids into smaller pieces. It is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyzes proteins. Trypsin is formed in the small intestine when its proenzyme form, the trypsinogen produced by the pancreas, is activated. Trypsin cuts peptide chains mainly at the carboxyl side of the amino acids lysine or arginine. It is used for numerous biotechnological processes. The process is commonly referred to as trypsin proteolysis or trypsinization, and proteins that have been digested/treated with trypsin are said to have been trypsinized. Trypsin was discovered in 1876 by Wilhelm Kühne and was named from the Ancient Greek word for rubbing since it was first isolated by rubbing the pancreas with glycerin. Function In the duodenum, trypsin catalyzes the hydrolysis of pept ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ketanserin
Ketanserin (INN, USAN, BAN) (brand name Sufrexal; former developmental code name R41468) is a drug used clinically as an antihypertensive agent and in scientific research to study the serotonin system; specifically, the 5-HT2 receptor family. It was discovered at Janssen Pharmaceutica in 1980. It is not available in the United States. Uses Medical uses Ketanserin is classified as an antihypertensive by the World Health Organization and the National Institute of Health. It has been used to reverse pulmonary hypertension caused by protamine (which in turn was administered to reverse the effects of heparin overdose). The reduction in hypertension is not associated with reflex tachycardia. It has been used in cardiac surgery. A 2000 Cochrane Review found that, compared to placebo, ketanserin did not provide significant relief for people suffering from Raynaud's phenomenon attacks in the setting of progressive systemic sclerosis (an autoimmune disorder). While the frequency of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trafermin
Trafermin (brand name Fiblast), also known as recombinant human basic fibroblast growth factor (rhbFGF), is a recombinant form of human basic fibroblast growth factor (bFGF) which is marketed in Japan as a topical spray for the treatment of skin ulcers. It is also currently in preregistration for the treatment of periodontitis. As a recombinant form of bFGF, trafermin is a potent agonist of the FGFR1, FGFR2, FGFR3, and FGFR4 Fibroblast growth factor receptor 4 is a protein that in humans is encoded by the ''FGFR4'' gene. FGFR4 has also been designated as CD334 (cluster of differentiation 334). The protein encoded by this gene is a member of the fibroblast growth fact .... The drug has been marketed in Japan since June 2001.Spaccapelo, L. RATIONALE FOR BASIC FGF IN WOUND HEALING AND REVIEW OF THERAPEUTIC APPLICATIONS. References External links Trafermin - AdisInsight Growth factors Human proteins Recombinant proteins {{dermatologic-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centella Asiatica
''Centella asiatica'', commonly known as gotu kola, kodavan, Indian pennywort and Asiatic pennywort, is a herbaceous, perennial plant in the flowering plant family Apiaceae. It is native to tropical regions of Africa, Asia, Australia, and islands in the western Pacific Ocean. It is consumed as a culinary vegetable and is used in traditional medicine. Description ''Centella'' grows in temperate and tropical swampy areas in many regions of the world. The stems are slender, creeping stolons, green to reddish-green in color, connecting plants to each other. It has long-stalked, green, rounded apices which have smooth texture with palmately netted veins. The leaves are borne on pericladial petioles, around . The rootstock consists of rhizomes, growing vertically down. They are creamish in color and covered with root hairs. The flowers are white or crimson in color, born in small, rounded bunches (umbels) near the surface of the soil. Each flower is partly enclosed in two green ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Betula
A birch is a thin-leaved deciduous hardwood tree of the genus ''Betula'' (), in the family Betulaceae, which also includes alders, hazels, and hornbeams. It is closely related to the beech-oak family Fagaceae. The genus ''Betula'' contains 30 to 60 known taxa of which 11 are on the IUCN 2011 Red List of Threatened Species. They are a typically rather short-lived pioneer species widespread in the Northern Hemisphere, particularly in northern areas of temperate climates and in boreal climates. Description Birch species are generally small to medium-sized trees or shrubs, mostly of northern temperate and boreal climates. The simple leaves are alternate, singly or doubly serrate, feather-veined, petiolate and stipulate. They often appear in pairs, but these pairs are really borne on spur-like, two-leaved, lateral branchlets. The fruit is a small samara, although the wings may be obscure in some species. They differ from the alders (''Alnus'', another genus in the family) i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetrachlorodecaoxide
"Tetrachlorodecaoxide" (TCDO) is a chlorite-containing substance with claimed immunomodulatory, macrophage-activating properties. WF10 (Macrokine, Immunokine, Oxoferin) is an aqueous solution of tetrachlorodecaoxide designed for intravenous injection. Tetrachlorodecaoxide/WF10 were originally developed by Oxo Chemie. The chemical formula is given as Cl4H2O114-. This incomplete formula shows a mixture of chlorite The chlorite ion, or chlorine dioxide anion, is the halite with the chemical formula of . A chlorite (compound) is a compound that contains this group, with chlorine in the oxidation state of +3. Chlorites are also known as salts of chlorou ... ion, water, and molecular oxygen: "Cl4H2O114-" = 4ClO2− + H2O + O2. Oxoferin was found to be equivalent with aqueous sodium chlorite. Tetrachlorodecaoxide / WF10 is used in the management of radiation cystitis, is effective in the treatment of diabetic foot ulcers, and is used in wound healing, where the mechanism of action ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cadexomer Iodine
Cadexomer iodine is an iodophor that is produced by the reaction of dextrin with epichlorhydrin coupled with ion-exchange groups and iodine. It is a water-soluble modified starch polymer containing 0.9% iodine, calculated on a weight-weight basis, within a helical matrix. History Cadexomer iodine was developed in the early 1980s in Sweden by Perstorp AB, and given the name Iodosorb. The product was shown to be effective in the treatment of venous ulcers,. More recently, it has been shown in studies in animals and humans that, unlike the iodophor povidone-iodine, Iodosorb causes an acceleration of the healing process in chronic human wounds. This is due to an increase in epidermal regeneration and epithelialization in both partial-thickness and full-thickness wounds. In this way cadexomer iodine acts as a cicatrizant. Properties When formulated as a topical wound dressing, Iodosorb adsorbs exudate and particulate matter from the surface of granulating wounds and, as the dressing be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Chlorite
Sodium chlorite (NaClO2) is a chemical compound used in the manufacturing of paper and as a disinfectant. Use The main application of sodium chlorite is the generation of chlorine dioxide for bleaching and stripping of textiles, pulp, and paper. It is also used for disinfection of municipal water treatment plants after conversion to chlorine dioxide. An advantage in this application, as compared to the more commonly used chlorine, is that trihalomethanes (such as chloroform) are not produced from organic contaminants. Chlorine dioxide generated from sodium chlorite is approved by FDA under some conditions for disinfecting water used to wash fruits, vegetables, and poultry. Sodium chlorite, NaClO2, sometimes in combination with zinc chloride, also finds application as a component in therapeutic rinses, mouthwashes, toothpastes and gels, mouth sprays, as preservative in eye drops, and in contact lens cleaning solution under the trade name Purite. It is also used for sanitizing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
