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Churchill–Cope Reflex
The Churchill–Cope reflex is a reflex in which distension of the pulmonary vascular bed, as occurs in pulmonary edema, causes an increase in respiratory rate (tachypnoea Tachypnea, also spelt tachypnoea, is a respiratory rate greater than normal, resulting in abnormally rapid and shallow breathing. In adult humans at rest, any respiratory rate of 1220 per minute is considered clinically normal, with tachypnea be ...) by stimulation of the juxtacapillary (J) receptors. It was described in 1929 by Edward Delos Churchill and Oliver Cope.Churchill ED, Cope O. The rapid shallow breathing resulting from pulmonary congestion and edema. ''J Exp Med'' 1929; 49:531-537Full text/ref> References Cardiovascular physiology Reflexes {{circulatory-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reflex
In biology, a reflex, or reflex action, is an involuntary, unplanned sequence or action and nearly instantaneous response to a stimulus. Reflexes are found with varying levels of complexity in organisms with a nervous system. A reflex occurs via neural pathways in the nervous system called reflex arcs. A stimulus initiates a neural signal, which is carried to a synapse. The signal is then transferred across the synapse to a motor neuron which evokes a target response. These neural signals do not always travel to the brain, so many reflexes are an automatic response to a stimulus that does not receive or need conscious thought. Many reflexes are fine-tuned to increase organism survival and self-defense. This is observed in reflexes such as the startle reflex, which provides an automatic response to an unexpected stimuli, and the feline righting reflex, which reorients a cat's body when falling to ensure safe landing. The simplest type of reflex, a short-latency reflex, has a s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pulmonary Edema
Pulmonary edema, also known as pulmonary congestion, is excessive edema, liquid accumulation in the parenchyma, tissue and pulmonary alveolus, air spaces (usually alveoli) of the lungs. It leads to impaired gas exchange and may cause hypoxemia and respiratory failure. It is due to either failure of the left ventricle of the heart to remove oxygenated blood adequately from the pulmonary circulation (cardiogenic pulmonary edema), or an injury to the lung parenchyma, lung tissue directly or blood vessels of the lung (non-cardiogenic pulmonary edema). Treatment is focused on three aspects: firstly improving respiratory function, secondly, treating the underlying cause, and thirdly preventing further damage and assuring full recovery to the lung. Pulmonary edema, especially when sudden (acute), can lead to respiratory failure or cardiac arrest due to Hypoxia (medical), hypoxia. It is a cardinal feature of congestive heart failure. The term edema is from the Greek language, Greek (''oi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Respiratory Rate
The respiratory rate is the rate at which breathing occurs; it is set and controlled by the respiratory center of the brain. A person's respiratory rate is usually measured in breaths per minute. Measurement The respiratory rate in humans is measured by counting the number of breaths for one minute through counting how many times the chest rises. A fibre-optic breath rate sensor can be used for monitoring patients during a magnetic resonance imaging scan. Respiration rates may increase with fever, illness, or other medical conditions. Inaccuracies in respiratory measurement have been reported in the literature. One study compared respiratory rate counted using a 90-second count period, to a full minute, and found significant differences in the rates.. Another study found that rapid respiratory rates in babies, counted using a stethoscope, were 60–80% higher than those counted from beside the cot without the aid of the stethoscope. Similar results are seen with animals when th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tachypnoea
Tachypnea, also spelt tachypnoea, is a respiratory rate greater than normal, resulting in abnormally rapid and shallow breathing. In adult humans at rest, any respiratory rate of 1220 per minute is considered clinically normal, with tachypnea being any rate above that. Children have significantly higher resting ventilatory rates, which decline rapidly during the first three years of life and then steadily until around 18 years. Tachypnea can be an early indicator of pneumonia and other lung diseases in children, and is often an outcome of a brain injury. Distinction from other breathing terms Different sources produce different classifications for breathing terms. Some of the public describe tachypnea as any rapid breathing. Hyperventilation is then described as increased ventilation of the alveoli (which can occur through increased rate or depth of breathing, or a mix of both) where there is a smaller rise in metabolic carbon dioxide relative to this increase in ventilation. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Juxtacapillary (J) Receptors
Juxtacapillary receptors, J-receptors, or pulmonary C-fiber receptors are sensory nerve endings located within the alveolar walls in juxtaposition to the pulmonary capillaries of the lung, and are innervated by fibers of the vagus nerve. Although their functional role is unclear, J-receptors respond to events such as pulmonary edema, pulmonary emboli, pneumonia, congestive heart failure and barotrauma, which cause a decrease in oxygenation and thus lead to an increase in respiration. They may be also stimulated by hyperinflation of the lung as well as intravenous or intracardiac administration of chemicals such as capsaicin. The stimulation of the J-receptors causes a reflex increase in breathing rate, and is also thought to be involved in the sensation of dyspnea, the subjective sensation of difficulty breathing. The reflex response that is produced is apnea followed by rapid breathing, bradycardia Bradycardia (also sinus bradycardia) is a slow resting heart rate, commonly unde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Delos Churchill
Edward Delos Churchill (25 December 1895 – 28 August 1972) was an American surgeon known for his work in thoracic surgery and remembered for describing the Churchill-Cope reflex. Biography Edward Churchill was born on 25 December 1895 in Chenoa, Illinois. He attended Northwestern University, graduating B.S. in 1916 and M.A. in 1917. He then attended Harvard Medical School, graduating M.D. cum laude in 1920. He undertook his internship and residency at the Massachusetts General Hospital, and continued there as an associate surgeon; being named to that position in 1924. He studied in Europe on a Moseley Traveling Fellowship in 1926 and 1927, spending time in Copenhagen, Munich and Berlin.Art BaueEdward Delos Churchill. Pioneer, Educator; Leader in Surgery. The Massachusetts General Hospital Surgical Society Newsletter, vol 3, issue 1. Spring 2002. He returned to Massachusetts General in 1927, and moved to Boston City Hospital in 1928 to help found a full-time surgical unit ther ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oliver Cope
Oliver Cope (1902 - 30 April 1994), was an American surgeon known for his work in parathyroid surgery, burns treatment and breast cancer treatment. He is also remembered for describing the Churchill-Cope reflex. Biography Oliver Cope was born in 1902 in Germantown, Pennsylvania. He went to Haverford College in 1919, transferred to Harvard University the following year, and graduated in 1923. He then attended Harvard Medical School, graduating Doctor of Medicine, M.D. in 1928.Memorial Minute: Oliver Cope. ''Harvard University Gazette'', February 20, 1997. Accessed on 28 July 2010. His surgical training was carried out at Massachusetts General Hospital, where he became an assistant to Edward Delos Churchill. During this time he and Churchill published the findings of research which described the Chur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiovascular Physiology
Cardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular"). These subjects are sometimes addressed separately, under the names cardiac physiology and circulatory physiology. Although the different aspects of cardiovascular physiology are closely interrelated, the subject is still usually divided into several subtopics. Heart * Cardiac output (= heart rate * stroke volume. Can also be calculated with Fick principle,palpeting method.) ** Stroke volume (= end-diastolic volume − end-systolic volume) ** Ejection fraction (= stroke volume / end-diastolic volume) ** Cardiac output is mathematically ` to systole ** Inotropic, chronotropic, and dromotropic states ** Cardiac input (= heart rate * suction volume Can be calculated by inverting terms in Fick principle) ** Suction volume (= end-systolic volume + end-diastolic volume) ** Injection fraction (=suction volume / end-systolic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
