The Churchill–Cope reflex is a
reflex in which
distension of the pulmonary vascular bed, as occurs in
pulmonary edema
Pulmonary edema, also known as pulmonary congestion, is excessive liquid accumulation in the tissue and air spaces (usually alveoli) of the lungs. It leads to impaired gas exchange and may cause hypoxemia and respiratory failure. It is due t ...
, causes an increase in
respiratory rate
The respiratory rate is the rate at which breathing occurs; it is set and controlled by the respiratory center of the brain. A person's respiratory rate is usually measured in breaths per minute.
Measurement
The respiratory rate in humans is me ...
(
tachypnoea
Tachypnea, also spelt tachypnoea, is a respiratory rate greater than normal, resulting in abnormally rapid and shallow breathing.
In adult humans at rest, any respiratory rate of 1220 per minute is considered clinically normal, with tachypnea be ...
) by stimulation of the
juxtacapillary (J) receptors.
It was described in 1929 by
Edward Delos Churchill and
Oliver Cope.
[Churchill ED, Cope O. The rapid shallow breathing resulting from pulmonary congestion and edema. ''J Exp Med'' 1929; 49:531-537]
Full text
/ref>
References
Cardiovascular physiology
Reflexes
{{circulatory-stub