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Chrysoeriol
Chrysoeriol is a flavone, chemically the 3'-methoxy derivative of luteolin. Related compounds Diosmetin is one of three possible regioisomers of chrysoeriol. Natural sources Found in ''Artemisia''. Pharmacodynamics Vasorelaxant and hypotensive activity in vitro and in vivo in a murine model by intravenous infusion. See also * Cannflavin Cannflavins are a group of chemical compounds found in ''Cannabis sativa''. Chemically, they are prenylflavonoids and are unrelated to THC and other cannabinoids. Cannflavins A and B were first identified in the 1980s and cannflavin C was identif ...s, prenylated derivatives of chrysoeriol References External links Artemisia copa aqueous extract as vasorelaxant and hypotensive agent O-methylated flavones {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flavones
Flavones (from Latin ''flavus'' "yellow") are a class of flavonoids based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one) (as shown in the first image of this article). Flavones are common in foods, mainly from spices, and some yellow or orange fruits and vegetables. Common flavones include apigenin (4',5,7-trihydroxyflavone), luteolin (3',4',5,7-tetrahydroxyflavone), tangeritin (4',5,6,7,8-pentamethoxyflavone), chrysin (5,7-dihydroxyflavone), and 6-hydroxyflavone. Intake and elimination The estimated daily intake of flavones is about 2 mg per day. Following ingestion and metabolism, flavones, other polyphenols, and their metabolites are absorbed poorly in body organs and are rapidly excreted in the urine, indicating mechanisms influencing their presumed absence of metabolic roles in the body. Drug interactions Flavones have effects on CYP (P450) activity, which are enzymes that metabolize most drugs in the body. Biosynthesis The biosynthesis of f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luteolin
Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance. Luteolin is the principal yellow dye compound that is obtained from the plant ''Reseda luteola'', which has been used as a source of the dye since at least the first millennium B.C. Luteolin was first isolated in pure form, and named, in 1829 by the French chemist Michel Eugène Chevreul. The luteolin empirical formula was determined by the Austrian chemists Heinrich Hlasiwetz and Leopold Pfaundler in 1864. In 1896, the English chemist Arthur George Perkin proposed the correct structure for luteolin. Perkin's proposed structure for luteolin was confirmed in 1900 when the Polish-Swiss chemist Stanislaw Kostanecki (1860–1910) and his students A. Różycki and J. Tambor synthesized luteolin. Natural occurrences Luteolin is most often found in leaves, but it is also seen in rinds, barks, clover blossom, and ragweed pollen. It has also been isolated from the aromatic flowering plant, ''Salvia t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diosmetin
Diosmetin, also known as 5,7,3′-trihydroxy-4′-methoxyflavone, is an ''O''-methylated flavone, a chemical compound that can be found in the Caucasian vetch. It has been found to act as a weak TrkB receptor agonist. Glycosides Diosmetin is the aglycone of diosmin Diosmin (diosmetin 7-O-rutinoside), a flavone glycoside of diosmetin, is manufactured from citrus fruit peels as a phlebotonic non-prescription dietary supplement used to aid treatment of hemorrhoids or chronic venous diseases, mainly of the le .... See also * Tropomyosin receptor kinase B § Agonists References O-methylated flavones Resorcinols TrkB agonists 3-Hydroxypropenals within hydroxyquinones {{Aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regioisomer
In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a compound is another compound whose molecule has the same number of atoms of each element, but with logically distinct bonds between them. The term metamer was formerly used for the same concept. For example, butanol , methyl propyl ether , and diethyl ether have the same molecular formula but are three distinct structural isomers. The concept applies also to polyatomic ions with the same total charge. A classical example is the cyanate ion and the fulminate ion . It is also extended to ionic compounds, so that (for example) ammonium cyanate and urea are considered structural isomers,William F. Bynum, E. Janet Browne, Roy Porter (2014): ''Dictionary of the History of Science''. 530 pages. and so are methylammonium formate and ammonium acetate . Structural isomerism is the most radical type of isomerism. It is opposed to stereoisomerism, in which the atoms and bonding scheme ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artemisia (genus)
''Artemisia'' () is a large, diverse genus of plants with between 200 and 400 species belonging to the daisy family Asteraceae. Common names for various species in the genus include mugwort, wormwood, and sagebrush. ''Artemisia'' comprises hardy herbaceous plants and shrubs, which are known for the powerful chemical constituents in their essential oils. ''Artemisia'' species grow in temperate climates of both hemispheres, usually in dry or semiarid habitats. Notable species include '' A. vulgaris'' (common mugwort), '' A. tridentata'' (big sagebrush), '' A. annua'' (sagewort), '' A. absinthium'' (wormwood), ''A. dracunculus'' (tarragon), and '' A. abrotanum'' (southernwood). The leaves of many species are covered with white hairs. Most species have strong aromas and bitter tastes from terpenoids and sesquiterpene lactones, which discourage herbivory, and may have had a selective advantage. The small flowers are wind-pollinated. ''Artemisia'' species are used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cannflavin
Cannflavins are a group of chemical compounds found in ''Cannabis sativa''. Chemically, they are prenylflavonoids and are unrelated to THC and other cannabinoids. Cannflavins A and B were first identified in the 1980s and cannflavin C was identified in 2008. Because cannflavins A and B are inhibitors of prostaglandin E2 production ''in vitro'', the cannflavins have been studied for their potential use as anti-inflammatory agents. Biosynthesis Cannflavins A and B are biosynthesized by prenylation of chrysoeriol Chrysoeriol is a flavone, chemically the 3'-methoxy derivative of luteolin. Related compounds Diosmetin is one of three possible regioisomer In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a compo .... References {{reflist Prenylflavonoids ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
