Chandipura Vesiculovirus
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Chandipura Vesiculovirus
''Chandipura vesiculovirus'' (CHPV) is a member of the ''Rhabdoviridae'' family that is associated with an encephalitic illness in humans. It was first identified in 1965 after isolation from the blood of two patients from Chandipura village in Maharashtra state, India and has been associated with a number of otherwise unexplained outbreaks of encephalitic illness in central India. The most recent occurred in Andhra Pradesh and Maharashtra in June–August 2003 with 329 children affected and 183 deaths. Further sporadic cases and deaths in children were observed in Gujarat state in 2004. ''Chandipura vesiculovirus'' has been isolated from sandflies in India and West Africa and is probably spread through its bite. The presence of the virus in Africa indicates a wide distribution although no human cases have been observed outside India. The significance of ''Chandipura vesiculovirus'' as a human pathogen is unresolved due to doubts over its role in the 2003 and 2004 outbreaks. ...
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Rhabdoviridae
''Rhabdoviridae'' is a family of negative-strand RNA viruses in the order ''Mononegavirales''. Vertebrates (including mammals and humans), invertebrates, plants, fungi and protozoans serve as natural hosts. Diseases associated with member viruses include rabies encephalitis caused by the rabies virus, and flu-like symptoms in humans caused by vesiculoviruses. The name is derived from Ancient Greek , meaning rod, referring to the shape of the viral particles. The family has 40 genera, most assigned to three subfamilies. Structure The individual virus particles (virions) of rhabdoviruses are composed of RNA, protein, carbohydrate and lipid. They have complex bacilliform or bullet-like shapes. All these viruses have structural similarities and have been classified as a single family. The virions are about 75 nm wide and 180 nm long. Rhabdoviruses are enveloped and have helical nucleocapsids and their genomes are linear, around 11–15 kb in length. Rhabdoviruses c ...
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Vadodara
Vadodara (), also known as Baroda, is the second largest city in the Indian state of Gujarat. It serves as the administrative headquarters of the Vadodara district and is situated on the banks of the Vishwamitri River, from the state capital of Gandhinagar. The railway line and National Highway 8, which connect Delhi with Mumbai, pass through Vadodara. The city is named for its abundance of the Banyan (''Vad'') tree. Vadodara is also locally referred to as the ''Sanskari Nagari'' () and ''Kala Nagari'' () of India. The city is prominent for landmarks such as the Laxmi Vilas Palace, which served as the residence of the Maratha royal Gaekwad dynasty that ruled over Baroda State. It is also the home of the Maharaja Sayajirao University of Baroda. Etymology The city in one period was called Chandanavati after the rule of Chanda of the Dodiya Rajputs. The capital was also known as Virakshetra or Viravati (Land of Warriors). Later on, it was known as Vadpatraka or Vadodará, and ...
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Ahmedabad
Ahmedabad ( ; Gujarati: Amdavad ) is the most populous city in the Indian state of Gujarat. It is the administrative headquarters of the Ahmedabad district and the seat of the Gujarat High Court. Ahmedabad's population of 5,570,585 (per the 2011 population census) makes it the fifth-most populous city in India, and the encompassing urban agglomeration population estimated at 6,357,693 is the seventh-most populous in India. Ahmedabad is located near the banks of the Sabarmati River, from the capital of Gujarat, Gandhinagar, also known as its twin city. Ahmedabad has emerged as an important economic and industrial hub in India. It is the second-largest producer of cotton in India, due to which it was known as the 'Manchester of India' along with Kanpur. Ahmedabad's stock exchange (before it was shut down in 2018) was the country's second oldest. Cricket is a popular sport in Ahmedabad; a newly built stadium, called Narendra Modi Stadium, at Motera can accommodate 132,0 ...
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Sandfly
Sandfly (or sand fly) is a colloquial name for any species or genus of flying, biting, blood-sucking dipteran (fly) encountered in sandy areas. In the United States, ''sandfly'' may refer to certain horse flies that are also known as "greenheads" (family Tabanidae), or to members of the family Ceratopogonidae. The bites usually result in a small, intensely itchy bump or welt, the strength of which intensifies over a period of 5-7 days before dissipating. Moderate relief is achieved with varying success through the application of over the counter products such as Benadryl (ingested) or an analgesic cream such as After Bite (applied topically). Outside the United States, ''sandfly'' may refer to members of the subfamily Phlebotominae within the Psychodidae. Biting midges (Ceratopogonidae) are sometimes called sandflies or no-see-ums (no-see-em, noseeum). New Zealand sandflies are in the genus ''Austrosimulium'', a type of black fly. In the various sorts of sandfly only the fema ...
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Panchmahal District
Panchmahal, also known as Panch Mahals, is a district in the eastern portion of Gujarat State western India. ''Panch-mahal'' means "five tehsils/talukas" (5 sub-divisions), and refers to the five sub-divisions that were transferred by the Maharaja Jivajirao Scindia of Gwalior State to the British: Godhra, Dahod, Halol, Kalol and Jhalod, Devgadh Baria. The district had a population of 2,390,776 of which 12.51% were urban as of 2001. The district is located on eastern end of the state. It is bordered by Dahod district to the north-east & east, Vadodara district to the southwest and Chhota Udaipur district to southeast, Kheda district to the west and Mahisagar district to the north. Name ''Panch-mahal'' is a Hindustani or Gujarati word derived from Panch ("five") and Mahal which adopted from its original usage in Arabic for a place or type of building, later adopted in Hindi to refer to a province, district or its division, an estate etc. The district was originally called the ...
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Vadodara District
Vadodara District also known as Baroda District is a district in the eastern part of the state of Gujarat in western India. The city of Vadodara (Baroda), in the western part of the district, is the administrative headquarters. Vadodara District covers an area of 7,794 km2. As of 2011, the district had a population of 4,393,796 of which 49.6% were urban, 50.4% were rural, 5.3% were Scheduled castes and 27.6% were Scheduled tribes. As of 2011 it is the third most populous district of Gujarat (out of 33 Climate The Vadodara district has a dry climate and three distinct seasons, namely summer, winter and monsoon. Divisions Vadodara is divided into 2 Prants: # Vadodara # Dabhoi Vadodara is divided into 8 talukas: # Dabhoi # Karjan # Padra # Savli # Sinor # Vadodara City # Vadodara Rural # Waghodia Demographics According to the 2011 census Vadodara district has a population of 4,165,626, The district has a population density of . Its population growth rate over the d ...
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Kheda District
Kheda District is one of the thirty-three districts of Gujarat state in western India. Its central city, Kheda, is the administrative headquarters of the district. History Formerly known as Kaira district, it was divided in two with the southern part becoming Anand district in 1997. The Charotar region of Kaira consisted of four talukas (sub-districts): Nadiad, Anand, Borsad, and Petlad. When the district was divided, Nadiad Taluka went with Kheda district and the other three with Anand district. Today, Kheda has eleven talukas. Balasinor and Virpur, once in Kheda district, were moved to the newly formed Mahisagar district in 2013. During the Indian independence movement in the first half of the 20th century, the Patidars of the Charotar region and other areas in Kaira resisted the British in a number of standoffs, notably the Kaira anti-tax campaign of 1913, the Kheda Satyagraha of 1918, the Borsad Satyagraha of 1923, and the Bardoli Satyagraha of 1928. Demographics A ...
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Polycistronic
A cistron is an alternative term for "gene". The word cistron is used to emphasize that genes exhibit a specific behavior in a cis-trans test; distinct positions (or loci) within a genome are cistronic. History The words ''cistron'' and ''gene'' were coined before the advancing state of biology made it clear that the concepts they refer to are practically equivalent. The same historical naming practices are responsible for many of the synonyms in the life sciences. The term cistron was coined by Seymour Benzer in an article entitled ''The elementary units of heredity''. also reprinted in The cistron was defined by an operational test applicable to most organisms that is sometimes referred to as a cis-trans test, but more often as a complementation test. Definition For example, suppose a mutation at a chromosome position x is responsible for a change in recessive trait in a diploid organism (where chromosomes come in pairs). We say that the mutation is recessive because the ...
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Encephalitis
Encephalitis is inflammation of the brain. The severity can be variable with symptoms including reduction or alteration in consciousness, headache, fever, confusion, a stiff neck, and vomiting. Complications may include seizures, hallucinations, trouble speaking, memory problems, and problems with hearing. Causes of encephalitis include viruses such as herpes simplex virus and rabies virus as well as bacteria, fungi, or parasites. Other causes include autoimmune diseases and certain medications. In many cases the cause remains unknown. Risk factors include a weak immune system. Diagnosis is typically based on symptoms and supported by blood tests, medical imaging, and analysis of cerebrospinal fluid. Certain types are preventable with vaccines. Treatment may include antiviral medications (such as acyclovir), anticonvulsants, and corticosteroids. Treatment generally takes place in hospital. Some people require artificial respiration. Once the immediate problem is under co ...
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Cytosolic
The cytosol, also known as cytoplasmic matrix or groundplasm, is one of the liquids found inside cells (intracellular fluid (ICF)). It is separated into compartments by membranes. For example, the mitochondrial matrix separates the mitochondrion into many compartments. In the eukaryotic cell, the cytosol is surrounded by the cell membrane and is part of the cytoplasm, which also comprises the mitochondria, plastids, and other organelles (but not their internal fluids and structures); the cell nucleus is separate. The cytosol is thus a liquid matrix around the organelles. In prokaryotes, most of the chemical reactions of metabolism take place in the cytosol, while a few take place in membranes or in the periplasmic space. In eukaryotes, while many metabolic pathways still occur in the cytosol, others take place within organelles. The cytosol is a complex mixture of substances dissolved in water. Although water forms the large majority of the cytosol, its structure and propertie ...
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Sandfly
Sandfly (or sand fly) is a colloquial name for any species or genus of flying, biting, blood-sucking dipteran (fly) encountered in sandy areas. In the United States, ''sandfly'' may refer to certain horse flies that are also known as "greenheads" (family Tabanidae), or to members of the family Ceratopogonidae. The bites usually result in a small, intensely itchy bump or welt, the strength of which intensifies over a period of 5-7 days before dissipating. Moderate relief is achieved with varying success through the application of over the counter products such as Benadryl (ingested) or an analgesic cream such as After Bite (applied topically). Outside the United States, ''sandfly'' may refer to members of the subfamily Phlebotominae within the Psychodidae. Biting midges (Ceratopogonidae) are sometimes called sandflies or no-see-ums (no-see-em, noseeum). New Zealand sandflies are in the genus ''Austrosimulium'', a type of black fly. In the various sorts of sandfly only the fema ...
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