Centre For Geogenetics
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Centre For Geogenetics
The Centre for Geogenetics is a Danish Basic Research Centre of Excellence (Grundforskningscenter) which officially opened in September 2010. It is located at the Natural History Museum of Denmark, University of Copenhagen and financed by the Danish National Research Foundation. Research program The centre originally focused on questions related to evolutionary biology and geology, but has expanded into various health and disease related topics. The program currently includes: * How did the first human colonization of the Americas happen. The centre addresses the timing, routes and origin of these questions * Why, how and when did the timing, nature and causes of the Late Quaternary megafaunal extinctions happen * Origins, intermixing and migration routes of humans into the New World’s northern extremes (North America, Greenland) * Providing long-term insights into the response of polar ecosystems and coastal sea ice cover to global warming * Advance our understanding of the ...
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Natural History Museum Of Denmark
The Natural History Museum of Denmark ( da, Statens Naturhistoriske Museum) is a natural history museum located in Copenhagen, Denmark. It was created as a 1 January 2004 merger of Copenhagen's Zoological Museum This is a list of natural history museums, also known as museums of natural history, i.e. museums whose exhibits focus on the subject of natural history, including such topics as animals, plants, ecosystems, geology, paleontology, and cl ..., Geological Museum, Botanical Museum and Central Library, and Botanical Gardens. It is affiliated with the University of Copenhagen. History The Natural History Museum of Denmark was established on 1 January 2004 by the merging of four long-standing institutions: the Botanical Garden, the Botanical Museum & Central Library, the Geological Museum, and the Zoological Museum. The history of the individual departments, which now are part of the united Natural History Museum of Denmark, can be traced back to the 17th ce ...
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Holocene
The Holocene ( ) is the current geological epoch. It began approximately 11,650 cal years Before Present (), after the Last Glacial Period, which concluded with the Holocene glacial retreat. The Holocene and the preceding Pleistocene together form the Quaternary period. The Holocene has been identified with the current warm period, known as MIS 1. It is considered by some to be an interglacial period within the Pleistocene Epoch, called the Flandrian interglacial.Oxford University Press – Why Geography Matters: More Than Ever (book) – "Holocene Humanity" section https://books.google.com/books?id=7P0_sWIcBNsC The Holocene corresponds with the rapid proliferation, growth and impacts of the human species worldwide, including all of its written history, technological revolutions, development of major civilizations, and overall significant transition towards urban living in the present. The human impact on modern-era Earth and its ecosystems may be considered of global si ...
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Paleogenomics
Paleogenomics is a field of science based on the reconstruction and analysis of genomic information in extinct species. Improved methods for the extraction of ancient DNA (aDNA) from museum artifacts, ice cores, archeological or paleontological sites, and next-generation sequencing technologies have spurred this field. It is now possible to detect genetic drift, ancient population migration and interrelationships, the evolutionary history of extinct plant, animal and ''Homo'' species, and identification of phenotypic features across geographic regions. Scientists can also use paleogenomics to compare ancient ancestors against modern-day humans. The rising importance of paleogenomics is evident from the fact that the 2022 Nobel Prize in physiology or medicine was awarded to a Swedish geneticist Svante Pääbo 955- who worked on paleogenomics. Background Initially, aDNA sequencing involved cloning small fragments into bacteria, which proceeded with low efficiency due to the oxidati ...
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Full Genome Sequence
Whole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014. In the future of personalized medicine, whole genome sequence data may be an important tool to guide therapeutic intervention. The tool of gene sequencing at SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. Whole genome sequencing should not be confused with DNA prof ...
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Pleistocene/Holocene Megafauna Extinctions
The Late Pleistocene to the beginning of the Holocene saw the extinction of the majority of the world's megafauna (typically defined as animal species having body masses over ), which resulted in a collapse in faunal density and diversity across the globe. The extinctions during the Late Pleistocene are differentiated from previous extinctions by its extreme size bias towards large animals (with small animals being largely unaffected), and widespread absence of ecological succession to replace these extinct megafaunal species, and the regime shift of previously established faunal relationships and habitats as a consequence. The timing and severity of the extinctions varied by region and are thought to have been driven by varying combinations of human and climatic factors. Human impact on megafauna populations is thought to have been driven by hunting ("overkill"), as well as possibly environmental alteration. The relative importance of human vs climatic factors in the extinct ...
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