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Centre For Geogenetics
The Centre for Geogenetics is a Danish Basic Research Centre of Excellence (Grundforskningscenter) which officially opened in September 2010. It is located at the Natural History Museum of Denmark, University of Copenhagen and financed by the Danish National Research Foundation. Research program The centre originally focused on questions related to evolutionary biology and geology, but has expanded into various health and disease related topics. The program currently includes: * How did the first human colonization of the Americas happen. The centre addresses the timing, routes and origin of these questions * Why, how and when did the timing, nature and causes of the Late Quaternary megafaunal extinctions happen * Origins, intermixing and migration routes of humans into the New World’s northern extremes (North America, Greenland) * Providing long-term insights into the response of polar ecosystems and coastal sea ice cover to global warming * Advance our understanding of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural History Museum Of Denmark
The Natural History Museum of Denmark ( da, Statens Naturhistoriske Museum) is a natural history museum located in Copenhagen, Denmark. It was created as a 1 January 2004 merger of Copenhagen's Zoological Museum This is a list of natural history museums, also known as museums of natural history, i.e. museums whose exhibits focus on the subject of natural history, including such topics as animals, plants, ecosystems, geology, paleontology, and cl ..., Geological Museum, Botanical Museum and Central Library, and Botanical Gardens. It is affiliated with the University of Copenhagen. History The Natural History Museum of Denmark was established on 1 January 2004 by the merging of four long-standing institutions: the Botanical Garden, the Botanical Museum & Central Library, the Geological Museum, and the Zoological Museum. The history of the individual departments, which now are part of the united Natural History Museum of Denmark, can be traced back to the 17th ce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Holocene
The Holocene ( ) is the current geological epoch. It began approximately 11,650 cal years Before Present (), after the Last Glacial Period, which concluded with the Holocene glacial retreat. The Holocene and the preceding Pleistocene together form the Quaternary period. The Holocene has been identified with the current warm period, known as MIS 1. It is considered by some to be an interglacial period within the Pleistocene Epoch, called the Flandrian interglacial.Oxford University Press – Why Geography Matters: More Than Ever (book) – "Holocene Humanity" section https://books.google.com/books?id=7P0_sWIcBNsC The Holocene corresponds with the rapid proliferation, growth and impacts of the human species worldwide, including all of its written history, technological revolutions, development of major civilizations, and overall significant transition towards urban living in the present. The human impact on modern-era Earth and its ecosystems may be considered of global si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paleogenomics
Paleogenomics is a field of science based on the reconstruction and analysis of genomic information in extinct species. Improved methods for the extraction of ancient DNA (aDNA) from museum artifacts, ice cores, archeological or paleontological sites, and next-generation sequencing technologies have spurred this field. It is now possible to detect genetic drift, ancient population migration and interrelationships, the evolutionary history of extinct plant, animal and ''Homo'' species, and identification of phenotypic features across geographic regions. Scientists can also use paleogenomics to compare ancient ancestors against modern-day humans. The rising importance of paleogenomics is evident from the fact that the 2022 Nobel Prize in physiology or medicine was awarded to a Swedish geneticist Svante Pääbo 955- who worked on paleogenomics. Background Initially, aDNA sequencing involved cloning small fragments into bacteria, which proceeded with low efficiency due to the oxidati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Full Genome Sequence
Whole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014. In the future of personalized medicine, whole genome sequence data may be an important tool to guide therapeutic intervention. The tool of gene sequencing at SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. Whole genome sequencing should not be confused with DNA prof ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pleistocene/Holocene Megafauna Extinctions
The Late Pleistocene to the beginning of the Holocene saw the extinction of the majority of the world's megafauna (typically defined as animal species having body masses over ), which resulted in a collapse in faunal density and diversity across the globe. The extinctions during the Late Pleistocene are differentiated from previous extinctions by its extreme size bias towards large animals (with small animals being largely unaffected), and widespread absence of ecological succession to replace these extinct megafaunal species, and the regime shift of previously established faunal relationships and habitats as a consequence. The timing and severity of the extinctions varied by region and are thought to have been driven by varying combinations of human and climatic factors. Human impact on megafauna populations is thought to have been driven by hunting ("overkill"), as well as possibly environmental alteration. The relative importance of human vs climatic factors in the extinct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of regulatory RNAs. It also includes promoters and their associated gene-regulatory elements, DNA playing structural and replicatory roles, such as scaffolding regions, telomeres, centromeres, and origins of replication, plus large numbers of transposable elements, inserted viral DNA, non-functional pseudogenes and simple, highly-repetitive sequences. Introns make up a large percentage of non-coding DNA. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science (journal)
''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature (journal), Nature'' c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Late Pleistocene
The Late Pleistocene is an unofficial Age (geology), age in the international geologic timescale in chronostratigraphy, also known as Upper Pleistocene from a Stratigraphy, stratigraphic perspective. It is intended to be the fourth division of the Pleistocene Epoch within the ongoing Quaternary Period. It is currently defined as the time between c. 129,000 and c. 11,700 years ago. The Late Pleistocene equates to the proposed Tarantian Age of the geologic time scale, preceded by the officially ratified Chibanian (formerly known as Middle Pleistocene) and succeeded by the officially ratified Greenlandian. The estimated beginning of the Tarantian is the start of the Eemian interglacial period (Marine Isotope Stage 5). It is held to end with the termination of the Younger Dryas, some 10th millennium BC, 11,700 years ago when the Holocene Epoch began. The term Upper Pleistocene is currently in use as a provisional or "quasi-formal" designation by the International Union of Geological ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Copenhagen
The University of Copenhagen ( da, Københavns Universitet, KU) is a prestigious public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia after Uppsala University, and ranks as one of the top universities in the Nordic countries, Europe and the world. Its establishment sanctioned by Pope Sixtus IV, the University of Copenhagen was founded by Christian I of Denmark as a Catholic teaching institution with a predominantly Theology, theological focus. In 1537, it was re-established by King Christian III as part of the Lutheran Reformation. Up until the 18th century, the university was primarily concerned with educating clergymen. Through various reforms in the 18th and 19th century, the University of Copenhagen was transformed into a modern, Secularism, secular university, with science and the humanities replacing theology as the main subjects studied and taught. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quaternary
The Quaternary ( ) is the current and most recent of the three periods of the Cenozoic Era in the geologic time scale of the International Commission on Stratigraphy (ICS). It follows the Neogene Period and spans from 2.58 million years ago to the present. The Quaternary Period is divided into two epochs: the Pleistocene (2.58 million years ago to 11.7 thousand years ago) and the Holocene (11.7 thousand years ago to today, although a third epoch, the Anthropocene, has been proposed but is not yet officially recognised by the ICS). The Quaternary Period is typically defined by the cyclic growth and decay of continental ice sheets related to the Milankovitch cycles and the associated climate and environmental changes that they caused. Research history In 1759 Giovanni Arduino proposed that the geological strata of northern Italy could be divided into four successive formations or "orders" ( it, quattro ordini). The term "quaternary" was introduced by Jules Desnoye ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ancient DNA
Ancient DNA (aDNA) is DNA isolated from ancient specimens. Due to degradation processes (including cross-linking, deamination and fragmentation) ancient DNA is more degraded in comparison with contemporary genetic material. Even under the best preservation conditions, there is an upper boundary of 0.4–1.5 million years for a sample to contain sufficient DNA for sequencing technologies. The oldest sample ever sequenced is estimated to be 1.65 million years old. Genetic material has been recovered from paleo/archaeological and historical skeletal material, mummified tissues, archival collections of non-frozen medical specimens, preserved plant remains, ice and from permafrost cores, marine and lake sediments and excavation dirt. On 7 December 2022, ''The New York Times'' reported that two-million year old genetic material was found in Greenland, and is currently considered the oldest DNA discovered so far. History of ancient DNA studies 1980s The first study of what would ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
