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Centre For Life
The Centre for Life is a science village in Newcastle upon Tyne where scientists, clinicians, educationalists and business people work to promote the advancement of the life sciences. The centre is a registered charity, governed by a board of trustees, which receives no public funding. History The centre was opened by the Queen in May 2000. In March 2009 the centre was the main venue for the UK's first Maker Faire, run as part of the Newcastle ScienceFest. The 2010 Newcastle Maker Faire was held at the Centre for Life and the nearby Discovery Museum. Maker Faire UK returned to the Centre for Life in 2013, at which over 300 hackers, crafters, coders, DIYers and inventors presented their projects alongside installations and drop-in workshops, and also in 2016. Life Science Centre The Life Science Centre is a visitor attraction at the International Centre for Life. It has a changing programme of events made up of temporary and permanent exhibitions, a Science Theatre, a planeta ...
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Newcastle Upon Tyne
Newcastle upon Tyne ( RP: , ), or simply Newcastle, is a city and metropolitan borough in Tyne and Wear, England. The city is located on the River Tyne's northern bank and forms the largest part of the Tyneside built-up area. Newcastle is also the most populous city of North East England. Newcastle developed around a Roman settlement called Pons Aelius and the settlement later took the name of a castle built in 1080 by William the Conqueror's eldest son, Robert Curthose. Historically, the city’s economy was dependent on its port and in particular, its status as one of the world's largest ship building and repair centres. Today, the city's economy is diverse with major economic output in science, finance, retail, education, tourism, and nightlife. Newcastle is one of the UK Core Cities, as well as part of the Eurocities network. Famous landmarks in Newcastle include the Tyne Bridge; the Swing Bridge; Newcastle Castle; St Thomas’ Church; Grainger Town including G ...
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Newcastle ScienceFest
Newcastle ScienceFest is a 10-day event at venues across NewcastleGateshead, with the principal aim of increasing the North East's enthusiasm for science and encouraging young people to consider a career in this area. Early history The first Science Festival programme in the city ran from 2002 – 2007. In 2008, funding from One NorthEast was awarded for an additional three festivals (2009–2011). The festival is delivered in partnership with Centre for Life, Tyne and Wear Museums, Newcastle Science City, Newcastle University, Newcastle City Council and culture10 as part of NewcastleGateshead’s world-class programme of festivals and events. Relaunch In 2009, the festival was re-launched with a new brand identity and website. There were three key strands of the programme catering for three different audiences; families, adults and schools. It included two family weekend events (7/8 & 14/15 March) and a series of adult events (lectures/science fiction/performances) during the we ...
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Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms become more common. The most obvious early symptoms are tremor, rigidity, slowness of movement, and difficulty with walking. Cognitive and behavioral problems may also occur with depression, anxiety, and apathy occurring in many people with PD. Parkinson's disease dementia becomes common in the advanced stages of the disease. Those with Parkinson's can also have problems with their sleep and sensory systems. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain, leading to a dopamine deficit. The cause of this cell death is poorly understood, but involves the build-up of misfolded proteins into Lewy bodies in the neurons. Collectively, the main motor symptoms are also known as ...
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term memory, remembering recent events. As the disease advances, symptoms can include primary progressive aphasia, problems with language, Orientation (mental), disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and challenging behaviour, behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an alle ...
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Diabetes
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to lo ...
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Embryos
An embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres are arranged as a solid ball that when reaching a certain size, called a morula, takes in fluid to create a cavity called a blastocoel. The structure is then termed a blastula, or a blastocyst in mammals. The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. Gastrulation is the formation of the three germ layers that will form all of the different parts of the body. Neurulation forms the nervous s ...
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Stem Cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50–150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. ''In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However ...
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Europe
Europe is a large peninsula conventionally considered a continent in its own right because of its great physical size and the weight of its history and traditions. Europe is also considered a Continent#Subcontinents, subcontinent of Eurasia and it is located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere. Comprising the westernmost peninsulas of Eurasia, it shares the continental landmass of Afro-Eurasia with both Africa and Asia. It is bordered by the Arctic Ocean to the north, the Atlantic Ocean to the west, the Mediterranean Sea to the south and Asia to the east. Europe is commonly considered to be Boundaries between the continents of Earth#Asia and Europe, separated from Asia by the drainage divide, watershed of the Ural Mountains, the Ural (river), Ural River, the Caspian Sea, the Greater Caucasus, the Black Sea and the waterways of the Turkish Straits. "Europe" (pp. 68–69); "Asia" (pp. 90–91): "A commonly accepted division between Asia and E ...
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Robert Winston
Robert Maurice Lipson Winston, Baron Winston, (born 15 July 1940) is a British professor, medical doctor, scientist, television presenter and Labour Party politician. Early life Robert Winston was born in London to Laurence Winston and Ruth Winston-Fox, and brought up as an Orthodox Jew. His mother was Mayor of the former Borough of Southgate. Winston's father died as a result of medical negligence when Winston was nine years old. Robert has two younger siblings: a sister, the artist Willow Winston, and a brother, Anthony.Robert Winston: 'I do have a very dark side'
''The Daily Telegraph'', 15 August 2008
Winston attended firstly

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Royal Victoria Infirmary
The Royal Victoria Infirmary (RVI) is a 673-bed tertiary referral hospital and research centre in Newcastle upon Tyne, England, with strong links to Newcastle University. The hospital is part of the Newcastle upon Tyne Hospitals NHS Foundation Trust and is a designated academic health science centre. History The original hospital was the Newcastle upon Tyne Infirmary at Forth Banks which was funded by way of public subscription. The foundation stone was laid by Joseph Butler, the Bishop of Durham, on 5 September 1751 and it opened on 8 October 1752. By the end of the 19th century, despite major extensions including the Dobson Wing which opened in 1855 and the Ravensworth Wards which opened in 1885, the infirmary became overcrowded and needed to be replaced. A new hospital to be known as the Royal Victoria Infirmary was designed by William Lister Newcomb and Percy Adams and built on of Town Moor given by the Corporation and Freemen of the City of Newcastle upon Tyne. It was op ...
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Newcastle University
Newcastle University (legally the University of Newcastle upon Tyne) is a UK public university, public research university based in Newcastle upon Tyne, North East England. It has overseas campuses in Singapore and Malaysia. The university is a red brick university and a member of the Russell Group, an association of research-intensive UK universities. The university finds its roots in the School of Medicine and Surgery (later the College of Medicine), established in 1834, and the Edward Fenwick Boyd#College of Physical Science, College of Physical Science (later renamed Armstrong College), founded in 1871. These two colleges came to form the larger division of the federal University of Durham, with the Durham Colleges forming the other. The Newcastle colleges merged to form King's College in 1937. In 1963, following an Act of Parliament, King's College became the University of Newcastle upon Tyne. The university subdivides into three faculties: the Faculty of Humanities and ...
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National Health Service
The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom (UK). Since 1948, they have been funded out of general taxation. There are three systems which are referred to using the "NHS" name ( NHS England, NHS Scotland and NHS Wales). Health and Social Care in Northern Ireland was created separately and is often locally referred to as "the NHS". The four systems were established in 1948 as part of major social reforms following the Second World War. The founding principles were that services should be comprehensive, universal and free at the point of delivery—a health service based on clinical need, not ability to pay. Each service provides a comprehensive range of health services, free at the point of use for people ordinarily resident in the United Kingdom apart from dental treatment and optical care. In England, NHS patients have to pay prescription charges; some, such as those aged over 60 and certain state ben ...
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