Celobar Incident (Brazil, 2003)
The Celobar incident was a pharmaceutical fraud that occurred in Brazil in 2003, and resulted in the death of more than twenty TUBINO, M.: SIMONI, J. A. Reflecting about Celobar® case. New Chemist. n. 2, 2007. X-ray patients by barium poisoning.''Caso Celobar: diretores do laboratório fabricante do medicamento são condenados''Court Sentence Summary(in Portuguese) by JusBrasil Notícias Jurídicas, extracted from the Rio de Janeiro Court of Justice proceedings of January 30, 2009. Accessed on 2009-06-30.''Justiça condena 2 por mortes por Celobar''. Folha de S.Paulo, January 30, 2009Online versionaccessed on 2009-06030. Laboratório Enila was a small Brazilian pharmaceutics manufacturer who made an oral X-ray contrast medium trademarked Celobar. The medium's main ingredient was pharmaceutics-grade barium sulfate (BaSO4) imported from Germany. In 2003, without having the necessary expertise or authorization, they tried to manufacture BaSO4 in-house from much-cheaper technical-gr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pharmaceutical
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell therapies) ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rio De Janeiro
Rio de Janeiro ( , , ; literally 'River of January'), or simply Rio, is the capital of the state of the same name, Brazil's third-most populous state, and the second-most populous city in Brazil, after São Paulo. Listed by the GaWC as a beta global city, Rio de Janeiro is the sixth-most populous city in the Americas. Part of the city has been designated as a World Heritage Site, named "Rio de Janeiro: Carioca Landscapes between the Mountain and the Sea", on 1 July 2012 as a Cultural Landscape. Founded in 1565 by the Portuguese, the city was initially the seat of the Captaincy of Rio de Janeiro, a domain of the Portuguese Empire. In 1763, it became the capital of the State of Brazil, a state of the Portuguese Empire. In 1808, when the Portuguese Royal Court moved to Brazil, Rio de Janeiro became the seat of the court of Queen Maria I of Portugal. She subsequently, under the leadership of her son the prince regent João VI of Portugal, raised Brazil to the dignity of a k ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bankruptcy
Bankruptcy is a legal process through which people or other entities who cannot repay debts to creditors may seek relief from some or all of their debts. In most jurisdictions, bankruptcy is imposed by a court order, often initiated by the debtor. Bankrupt is not the only legal status that an insolvent person may have, and the term ''bankruptcy'' is therefore not a synonym for insolvency. Etymology The word ''bankruptcy'' is derived from Italian ''banca rotta'', literally meaning "broken bank". The term is often described as having originated in renaissance Italy, where there allegedly existed the tradition of smashing a banker's bench if he defaulted on payment so that the public could see that the banker, the owner of the bench, was no longer in a condition to continue his business, although some dismiss this as a false etymology. History In Ancient Greece, bankruptcy did not exist. If a man owed and he could not pay, he and his wife, children or servants were forced into " ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Goiânia Accident
The Goiânia accident was a radioactive contamination accident that occurred on September 13, 1987, in Goiânia, Goiás, Brazil, after a forgotten radiotherapy source was stolen from an abandoned hospital site in the city. It was subsequently handled by many people, resulting in four deaths. About 112,000 people were examined for radioactive contamination and 249 of them were found to have been contaminated. In the consequent cleanup operation, topsoil had to be removed from several sites, and several houses were demolished. All the objects from within those houses, including personal possessions, were seized and incinerated. ''Time'' magazine has identified the accident as one of the world's "worst nuclear disasters" and the International Atomic Energy Agency (IAEA) called it "one of the world's worst radiological incidents". Description of the source The radiation source in the Goiânia accident was a small capsule containing about of highly radioactive caesium chlori ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Goiás
Goiás () is a Brazilian state located in the Center-West region. Goiás borders the Federal District and the states of (from north clockwise) Tocantins, Bahia, Minas Gerais, Mato Grosso do Sul and Mato Grosso. The state capital is Goiânia. With 7.2 million inhabitants, Goiás is the most populous state in the Center-West and the 11th most populous in the country. It has the ninth largest economy among Brazilian federative units. In Brazil's geoeconomic division, Goiás belongs to the Centro-Sul (Center-South), being the northernmost state of the southern portion of Brazil. The state has 3.3% of the Brazilian population and is responsible for 2.7% of the Brazilian GDP. The history of Goiás dates back to the beginning of the 18th century, with the arrival of pioneers from São Paulo. The Rio Vermelho region was the first to be occupied, where Vila Boa (later renamed Goiás) was founded. The development and settlement of the state took place, in a more intensified way, start ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Oswaldo Cruz Institute
The Oswaldo Cruz Foundation (Portuguese ''Fundação Oswaldo Cruz'', also known as FIOCRUZ) is a scientific institution for research and development in biological sciences located in Rio de Janeiro, Brazil; it is considered one of the world's main public health research institutions. It was founded by Dr. Oswaldo Cruz, a noted physician and epidemiologist. The organization started in 1898 as the Federal SeroTherapy Institute with the objective of developing serum and vaccines against the bubonic plague. It was located outside Rio de Janeiro. The institute's activities, however, changed from simple production into research and experimental medicine, especially after Oswaldo Cruz assumed its leadership in 1902. From there on, the institute became the base for memorable sanitation campaigns in an age of outbreaks and epidemics of the bubonic plague, yellow fever, and smallpox. The institute, however, was not confined to Rio de Janeiro and collaborated in the occupation of the cou ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Barium
Barium is a chemical element with the symbol Ba and atomic number 56. It is the fifth element in group 2 and is a soft, silvery alkaline earth metal. Because of its high chemical reactivity, barium is never found in nature as a free element. The most common minerals of barium are baryte ( barium sulfate, BaSO4) and witherite (barium carbonate, BaCO3). The name ''barium'' originates from the alchemical derivative "baryta", from Greek (), meaning 'heavy'. ''Baric'' is the adjectival form of barium. Barium was identified as a new element in 1774, but not reduced to a metal until 1808 with the advent of electrolysis. Barium has few industrial applications. Historically, it was used as a getter for vacuum tubes and in oxide form as the emissive coating on indirectly heated cathodes. It is a component of YBCO (high-temperature superconductors) and electroceramics, and is added to steel and cast iron to reduce the size of carbon grains within the microstructure. Barium compounds ar ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nilópolis
Nilópolis (, , ) is a municipality in Brazil, located in the Rio de Janeiro state's southwestern region, bordering São João de Meriti, Mesquita and Rio de Janeiro. It is the smallest municipality in Rio de Janeiro state, with a total area of 19.39 km2. The population of 162,693 inhabitants living in an area of 9 km2 and the remaining area corresponds to the Gericinó's Natural Park. Officially, the population density exceeds 8,120 inhabitants/km2, but if calculated just 9 km2 occupied, it becomes the most densely populated city in Brazil with more than 17.400 inhabitants/km2. Currently, São João de Meriti has the highest population density, with 12,897 inhabitants/km2. The city was named after Nilo Peçanha, a President of Brazil. Beija Flor Nilópolis is famous for its ''Grêmio Recreativo Escola de Samba Beija-Flor de Nilópolis'', one of the most successful and luxurious Samba school A samba school ( pt, Escola de samba) is a dancing, marching, and dr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nova Iguaçu
Nova Iguaçu (, locally: or , ''New Iguaçu'') is a municipality in Rio de Janeiro state in Brazil. Location The city is named after the Iguaçu River that runs through it and empties into Guanabara Bay (not to be confused with the Iguaçu River in Paraná state, which forms the Iguaçu Falls). It is part of the Greater Rio de Janeiro metropolitan area. It was the state's second largest city in population until Mesquita was split off, and now it is the fourth largest behind São Gonçalo, Duque de Caxias and the state capital, Rio de Janeiro. It lies northwest of Rio de Janeiro, in the centre of the northern part of its metropolitan area, Baixada Fluminense. The current mayor is Rogério Lisboa ( PR). The city is the seat of the Roman Catholic Diocese of Nova Iguaçu. Nova Iguaçu has an estimated population of around 800,000 people. Although not best defined as a commuter town, it is a suburb of Rio de Janeiro under the influence of the capital – to which tens of thousand ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brazil
Brazil ( pt, Brasil; ), officially the Federative Republic of Brazil (Portuguese: ), is the largest country in both South America and Latin America. At and with over 217 million people, Brazil is the world's fifth-largest country by area and the seventh most populous. Its capital is Brasília, and its most populous city is São Paulo. The federation is composed of the union of the 26 States of Brazil, states and the Federal District (Brazil), Federal District. It is the largest country to have Portuguese language, Portuguese as an List of territorial entities where Portuguese is an official language, official language and the only one in the Americas; one of the most Multiculturalism, multicultural and ethnically diverse nations, due to over a century of mass Immigration to Brazil, immigration from around the world; and the most populous Catholic Church by country, Roman Catholic-majority country. Bounded by the Atlantic Ocean on the east, Brazil has a Coastline of Brazi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Carbonate
A carbonate is a salt of carbonic acid (H2CO3), characterized by the presence of the carbonate ion, a polyatomic ion with the formula . The word ''carbonate'' may also refer to a carbonate ester, an organic compound containing the carbonate group C(=O)(O–)2. The term is also used as a verb, to describe carbonation: the process of raising the concentrations of carbonate and bicarbonate ions in water to produce carbonated water and other carbonated beverageseither by the addition of carbon dioxide gas under pressure or by dissolving carbonate or bicarbonate salts into the water. In geology and mineralogy, the term "carbonate" can refer both to carbonate minerals and carbonate rock (which is made of chiefly carbonate minerals), and both are dominated by the carbonate ion, . Carbonate minerals are extremely varied and ubiquitous in chemically precipitated sedimentary rock. The most common are calcite or calcium carbonate, CaCO3, the chief constituent of limestone (as well a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Barium Carbonate
Barium carbonate is the inorganic compound with the formula BaCO3. Like most alkaline earth metal carbonates, it is a white salt that is poorly soluble in water. It occurs as the mineral known as witherite. In a commercial sense, it is one of the most important barium compounds. Preparation Barium carbonate is made commercially from barium sulfide by treatment with sodium carbonate at 60 to 70 °C (soda ash method) or, more commonly carbon dioxide at 40 to 90 °C: In the soda ash process, an aqueous solution of barium sulfide is treated with sodium carbonate: :BaS + H2O + CO2 → BaCO3 + H2S Reactions Barium carbonate reacts with acids such as hydrochloric acid to form soluble barium salts, such as barium chloride: : + 2 HCl → + + Pyrolysis of barium carbonate gives barium oxide. Uses It is mainly used to remove sulfate impurities from feedstock of the chlor-alkali process. Otherwise it is a common precursor to barium-containing compounds such as ferrites. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |