Catacamas Virus
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Catacamas Virus
Catacamas virus is a single-stranded, enveloped novel RNA virus in the genus ''Orthohantavirus'' of the order ''Bunyavirales'' isolated in ''Oryzomys couesi'' near the town of Catacamas in eastern Honduras. It is a member virus of ''Bayou orthohantavirus''. Natural reservoir Catacamas virus was isolated from ''Oryzomys couesi'' and none of 41 other rodents that were also trapped near the town of Catacamas. The finding represents the first time a hantavirus species has been found in Honduras. Virology Analysis of nucleotide and amino acid sequence data indicated that this hantaviral strain is phylogenetically most closely related to ''Bayou orthohantavirus'' which is associated with the marsh rice rat (''Oryzomys palustris The marsh rice rat (''Oryzomys palustris'') is a semiaquatic North American rodent in the family Cricetidae. It usually occurs in wetland habitats, such as swamps and salt marshes. It is found mostly in the eastern and southern United States, fr ...'') ...
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RNA Virus
An RNA virus is a virusother than a retrovirusthat has ribonucleic acid (RNA) as its genetic material. The nucleic acid is usually single-stranded RNA ( ssRNA) but it may be double-stranded (dsRNA). Notable human diseases caused by RNA viruses include the common cold, influenza, SARS, MERS, Covid-19, Dengue Virus, hepatitis C, hepatitis E, West Nile fever, Ebola virus disease, rabies, polio, mumps, and measles. The International Committee on Taxonomy of Viruses (ICTV) classifies RNA viruses as those that belong to ''Group III'', ''Group IV'' or ''Group V'' of the Baltimore classification system. This category excludes ''Group VI'', viruses with RNA genetic material but which use DNA intermediates in their life cycle: these are called retroviruses, including HIV-1 and HIV-2 which cause AIDS. As of May 2020, all known RNA viruses encoding an RNA-directed RNA polymerase are believed to form a monophyletic group, known as the realm '' Riboviria''. The majority of such RNA ...
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Orthohantavirus
''Orthohantavirus'' is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family ''Hantaviridae'' within the order ''Bunyavirales''. Members of this genus may be called orthohantaviruses or simply hantaviruses. Orthohantaviruses typically cause chronic asymptomatic infection in rodents. Humans may become infected with hantaviruses through contact with rodent urine, saliva, or feces. Some strains cause potentially fatal diseases in humans, such as hantavirus hemorrhagic fever with renal syndrome (HFRS), or hantavirus pulmonary syndrome (HPS), also known as hantavirus cardiopulmonary syndrome (HCPS), while others have not been associated with known human disease (e.g. Prospect Hill virus). HPS (HCPS) is a "rare respiratory illness associated with the inhalation of aerosolized rodent excreta (urine and feces) contaminated by hantavirus particles." Human infections of hantaviruses have almost entirely been linked to human contact with rodent excrement; however, ...
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Bunyavirales
''Bunyavirales'' is an order of segmented negative-strand RNA viruses with mainly tripartite genomes. Member viruses infect arthropods, plants, protozoans, and vertebrates. It is the only order in the class ''Ellioviricetes''. The name ''Bunyavirales'' derives from Bunyamwera, where the original type species ''Bunyamwera orthobunyavirus'' was first discovered. ''Ellioviricetes'' is named in honor of late virologist Richard M. Elliott for his early work on bunyaviruses. Bunyaviruses belong to the fifth group of the Baltimore classification system, which includes viruses with a negative-sense, single-stranded RNA genome. They have an enveloped, spherical virion. Though generally found in arthropods or rodents, certain viruses in this order occasionally infect humans. Some of them also infect plants. In addition, there is a group of bunyaviruses whose replication is restricted to arthropods and is known as insect-specific bunyaviruses. A majority of bunyaviruses are vector-borne ...
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Oryzomys Couesi
''Oryzomys couesi'', also known as Coues's rice rat, is a semiaquatic rodent in the family Cricetidae occurring from southernmost Texas through Mexico and Central America into northwestern Colombia. It is usually found in wet habitats, such as marshes, but also lives in drier forests and shrublands. Weighing about , ''O. couesi'' is a medium-sized to large rat. The coarse fur is buff to reddish above and white to buff below. The hindfeet show some specializations for life in the water, such as reduced ungual tufts of hair around the digits. It has 56 chromosomes. There is much geographic variation in size, proportions, color, and skull features. ''Oryzomys couesi'' is active during the night and builds nests of vegetation that are suspended among reeds about above the ground. It is an excellent swimmer and dives well, but can also climb in vegetation. An omnivore, it eats both plant and animal food, including seeds and insects. It breeds throughout the year; females giv ...
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Catacamas
Catacamas is a city, with a population of 59,990 (2020 calculation), and a municipality in the Olancho Department of Honduras. It is the largest municipality in Central America in terms of area. Overview Catacamas, called the ''Florida City'' by the great poet and writer Froylán Turcios, extends over a vast plain irrigated by the Rio Guayape in the heart of the luxuriant department of Olancho. The city is situated 210 km. north-east of the Honduran capital, Tegucigalpa, and is easily accessible by paved road. Catacamas has historically been characterised by the hospitality, resilience, and progressive spirit of its people, as well as its rich natural setting, which is suitable for both agricultural and forest production. It is located in a valley 450 meters above sea level. The North White Stone Mountain, part of Agalta Mountains National Park, is located near the city, which is home to a variety of botanical species such as conifers, broadleaf plants, and some 80 var ...
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Honduras
Honduras, officially the Republic of Honduras, is a country in Central America. The republic of Honduras is bordered to the west by Guatemala, to the southwest by El Salvador, to the southeast by Nicaragua, to the south by the Pacific Ocean at the Gulf of Fonseca, and to the north by the Gulf of Honduras, a large inlet of the Caribbean Sea. Its capital and largest city is Tegucigalpa. Honduras was home to several important Mesoamerican cultures, most notably the Maya, before the Spanish Colonization in the sixteenth century. The Spanish introduced Catholicism and the now predominant Spanish language, along with numerous customs that have blended with the indigenous culture. Honduras became independent in 1821 and has since been a republic, although it has consistently endured much social strife and political instability, and remains one of the poorest countries in the Western Hemisphere. In 1960, the northern part of what was the Mosquito Coast was transferred from Nicara ...
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Member Virus
In biology, a strain is a genetic variant, a subtype or Axenic, a culture within a biological species. Strains are often seen as inherently artificial concepts, characterized by a specific intent for genetic isolation. This is most easily observed in microbiology where strains are derived from a single cell Colony (biology)#Microbial colonies, colony and are typically quarantined by the physical constraints of a Petri dish. Strains are also commonly referred to within virology, botany, and with Animal testing on rodents, rodents used in experimental studies. Microbiology and virology It has been said that "there is no universally accepted definition for the terms 'strain', 'Variant (biology), variant', and 'isolate' in the virology community, and most virologists simply copy the usage of terms from others". A strain is a Genetics, genetic variant or subtype of a microorganism (e.g., a virus, bacterium or fungus). For example, a "flu strain" is a certain biological form of the i ...
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Bayou Orthohantavirus
''Bayou orthohantavirus'' (BAYV) is a species of ''Orthohantavirus'' first identified in 1993 in Louisiana. and later confirmed by other investigators. In 1996, the marsh rice rat was identified as the natural reservoir of the virus, indicating the virus to be widespread throughout the Southeastern United States. BAYV infection causes hantavirus pulmonary syndrome (HPS) and represents the second most common hantavirus in the United States behind the ''Sin Nombre orthohantavirus ''Sin Nombre orthohantavirus'' (SNV) (from Spanish, meaning "without a name") is the prototypical etiologic agent of hantavirus cardiopulmonary syndrome (HCPS). Discovered in 1993 near the Cañon de la Muerte on the Navajo Reservation, it was o ...''. References Hantaviridae {{Virus-stub ...
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Nucleotide
Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth. Nucleotides are obtained in the diet and are also synthesized from common nutrients by the liver. Nucleotides are composed of three subunit molecules: a nucleobase, a five-carbon sugar (ribose or deoxyribose), and a phosphate group consisting of one to three phosphates. The four nucleobases in DNA are guanine, adenine, cytosine and thymine; in RNA, uracil is used in place of thymine. Nucleotides also play a central role in metabolism at a fundamental, cellular level. They provide chemical energy—in the form of the nucleoside triphosphates, adenosine triphosphate (ATP), guanosine triphosphate (GTP), cytidine triphosphate (CTP) and uridine triphosphate (UTP)—throughout the cell for the many cellular func ...
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Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha amino acids appear in the genetic code. Amino acids can be classified according to the locations of the core structural functional groups, as Alpha and beta carbon, alpha- , beta- , gamma- or delta- amino acids; other categories relate to Chemical polarity, polarity, ionization, and side chain group type (aliphatic, Open-chain compound, acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling life ...
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Oryzomys Palustris
The marsh rice rat (''Oryzomys palustris'') is a semiaquatic North American rodent in the family Cricetidae. It usually occurs in wetland habitats, such as swamps and salt marshes. It is found mostly in the eastern and southern United States, from New Jersey and Kansas south to Florida and northeasternmost Tamaulipas, Mexico; its range previously extended further west and north, where it may have been a commensal in corn-cultivating communities. Weighing about , the marsh rice rat is a medium-sized rodent that resembles the common black and brown rat. The upperparts are generally gray-brown, but are reddish in many Florida populations. The feet show several specializations for life in the water. The skull is large and flattened, and is short at the front. John Bachman discovered the marsh rice rat in 1816, and it was formally described in 1837. Several subspecies have been described since the 1890s, mainly from Florida, but disagreement exists over their validity. The Florida Key ...
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Playa De Oro Virus
Playa de Oro virus (OROV) is a probable species of orthohantavirus found in the rodents ''Oryzomys couesi'' and ''Sigmodon mascotensis'' in the Mexican state of Colima. The former is thought to be the main host (biology), host. The DNA sequence, sequences of parts of the virus's RNA-based genome have been determined; they differ by 7–10% in amino acid composition and 22–24% in nucleotide composition from closely related viruses. Playa de Oro virus was identified as a new species in 2008 and is most closely related to Bayou virus, Catacamas virus, Muleshoe virus, and Black Creek Canal virus, found in other species of ''Oryzomys'' and ''Sigmodon''. Catacamas virus is found in a different population of ''Oryzomys couesi'', and the presence of different viruses in these two species has been used as an argument for classifying the two populations of the host as separate species. History and occurrence Playa de Oro virus was first identified in rodents collected in 2004 as part of ...
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