Cardiovirus B

	Cardiovirus B ''Cardiovirus B'' is a species in the genus ''Cardiovirus'' and is represented by two isolates, Saffold virus Saffold virus (SAFV) is a single-stranded RNA human virus belonging to the family ''Picornaviridae''. Discovered in 2007, it is the first human virus in the genus ''Cardiovirus'' and may provide a link to the development of multiple sclerosis or ... (SAFV) and Theiler's murine encephalomyelitis virus (TMEV). References Cardioviruses {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Cardiovirus Cardiovirus are a group of viruses within order ''Picornavirales'', family ''Picornaviridae''. Vertebrates serve as natural hosts for these viruses. Taxonomy There are currently six species in the genus: * ''Cardiovirus A'' * '' Cardiovirus B'' * '' Cardiovirus C'' * '' Cardiovirus D'' * '' Cardiovirus E'' * '' Cardiovirus F'' ''Cardiovirus A'' is composed of only one serotype, encephalomyocarditis virus (EMCV). ''Cardiovirus B'' consists of four viruses that are most probably serologically distinct. These are Theiler's Murine encephalomyelitis virus (TMEV), Vilyuisk human encephalomyelitis virus (VHEV), a Theiler-like rat virus (TRV) (which has yet to be named) and Saffold virus (SAF-V). Of these 4, only VHEV and SAF-V are thought to cause infection in humans. Thus far, ''Cardiovirus C'' has only been observed in the brown rat. Structure Cardioviruses are single-stranded RNA, non-enveloped viruses with icosahedral or spherical geometries, and a T=pseudo3 icosahedral capsid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Saffold Virus Saffold virus (SAFV) is a single-stranded RNA human virus belonging to the family ''Picornaviridae''. Discovered in 2007, it is the first human virus in the genus ''Cardiovirus'' and may provide a link to the development of multiple sclerosis or other serious diseases in humans. The Saffold virus was previously a member of the Theilovirus species but was re-classified in 2019 as an isolate of the species ''Cardiovirus D''. It has shown to affect the gastrointestinal tract and respiratory systems, and is found to be present early in life. Discovery SAFV was discovered by Morris S. Jones in 2007 while working at the David Grant USAF Medical Center in the United States. The virus was isolated from a stool sample taken in November 1981 from an 8-month-old female with fever of unknown origin. This is the first human virus in the genus ''Cardiovirus''. Found to occur in high prevalence (>90%) among humans, by analogy SAFV may have effects similar to those observed in mouse TMEV-indu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Theiler's Encephalomyelitis Virus Theiler's murine encephalomyelitis virus (TMEV) is a single-stranded RNA murine cardiovirus from the family ''Picornaviridae''. It has been used as a mouse model for studying virally induced paralysis, as well as encephalomyelitis comparable to multiple sclerosis. Depending on the mouse and viral strain, viral pathogenesis can range from negligible, to chronic or acute encephalomyelitis. Discovery The virus was discovered by virologist Max Theiler in 1937 while working at the Rockefeller University, Rockefeller Institute. Theiler discovered the encephalomyelitis virus during research on poliovirus-like paralysis symptoms in mice. That year Theiler had completed work on developing a vaccine for yellow fever, for which he is best known; in 1951 he received the Nobel Prize for that achievement. Strains The several different strains of TMEV are characterized by their pathology as well as DNA sequencing, genetic sequencing and proteomics. The two major groups are listed below; th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]