Carbogen
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Carbogen
Carbogen, also called Meduna's Mixture after its inventor Ladislas J. Meduna, Ladislas Meduna, is a mixture of carbon dioxide and oxygen gas. Meduna's original formula was 30% CO2 and 70% oxygen, but the term carbogen can refer to any mixture of these two gases, from 1.5%Prisman E, Slessarev M, Azami T, Nayot D, Milosevic M, and Fisher J. (2007). Modified oxygen mask to induce target levels of hyperoxia and hypercarbia during radiotherapy: a more effective alternative to carbogen. ''International Journal of Radiation Biology''. Jul;83(7):457-62. to 50%Erowid Carbogen Vault: Basics
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Mechanism

When carbogen is inhaled, the increased level of carbon dioxide causes a perception, both psychological and physiologica ...
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Carbon Dioxide
Carbon dioxide (chemical formula ) is a chemical compound made up of molecules that each have one carbon atom covalently double bonded to two oxygen atoms. It is found in the gas state at room temperature. In the air, carbon dioxide is transparent to visible light but absorbs infrared radiation, acting as a greenhouse gas. It is a trace gas in Earth's atmosphere at 421 parts per million (ppm), or about 0.04% by volume (as of May 2022), having risen from pre-industrial levels of 280 ppm. Burning fossil fuels is the primary cause of these increased CO2 concentrations and also the primary cause of climate change.IPCC (2022Summary for policy makersiClimate Change 2022: Mitigation of Climate Change. Contribution of Working Group III to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA Carbon dioxide is soluble in water and is found in groundwater, lakes, ice caps, ...
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Ladislas J
Ladislav is a Czech, Slovak and Croatian variant of the Slavic name Vladislav. The female form of this name is Ladislava. Folk etymology occasionally links ''Ladislav'' with the Slavic goddess Lada. Spellings and variations In Bulgarian and Russian this name is spelled in . ''László'' is a Hungarian variation of this name. Athletes *Ladislav Beneš, Czechoslovak Olympic handball player * Ladislav Benýšek, Czech ice hockey player *Ladislav Čepčianský, Czechoslovak sprint canoer *Ladislav Dluhoš, Czechoslovak ski jumper *Ladislav Fouček * Ladislav Hecht (1909–2004), Czechoslovak/American tennis player *Ladislav Hrubý, cross-country skier *Ladislav Jurkemik, Czechoslovak/Slovak footballer and manager *Ladislav Kačáni, Czechoslovak footballer and coach *Ladislav Kohn, Czech ice hockey player *Ladislav Kuna, Czechoslovak footballer *Ladislav Lubina, Czechoslovak ice hockey player and coach *Ladislav Maier, Czech footballer *Ladislav Nagy, Slovak ice hockey p ...
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Psychedelic Drug Research
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence'' Sometimes, they are called classic hallucinogens, serotonergic hallucinogens, or serotonergic psychedelics, and the term ''psychedelics'' is used more broadly to include all hallucinogens; this article uses the narrower definition of ''psychedelics''. Psychedelics cause specific psychological, visual, and auditory changes, and often a substantially altered state of consciousness.Leary, Timothy; Metzner, Ralph (1964). ''The Psychedelic Experience: A Manual Based on The Tibetan Book of the Dead'' Psychedelic states are often compared to meditative, psychodynamic or transcendental types of alterations of mind. The "classical" psychedelics, the psyc ...
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Gases
Gas is one of the four fundamental states of matter (the others being solid, liquid, and plasma). A pure gas may be made up of individual atoms (e.g. a noble gas like neon), elemental molecules made from one type of atom (e.g. oxygen), or compound molecules made from a variety of atoms (e.g. carbon dioxide). A gas mixture, such as air, contains a variety of pure gases. What distinguishes a gas from liquids and solids is the vast separation of the individual gas particles. This separation usually makes a colourless gas invisible to the human observer. The gaseous state of matter occurs between the liquid and plasma states, the latter of which provides the upper temperature boundary for gases. Bounding the lower end of the temperature scale lie degenerative quantum gases which are gaining increasing attention. High-density atomic gases super-cooled to very low temperatures are classified by their statistical behavior as either Bose gases or Fermi gases. For a comprehensive li ...
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Experimental Medical Treatments
An experiment is a procedure carried out to support or refute a hypothesis, or determine the efficacy or likelihood of something previously untried. Experiments provide insight into cause-and-effect by demonstrating what outcome occurs when a particular factor is manipulated. Experiments vary greatly in goal and scale but always rely on repeatable procedure and logical analysis of the results. There also exist natural experimental studies. A child may carry out basic experiments to understand how things fall to the ground, while teams of scientists may take years of systematic investigation to advance their understanding of a phenomenon. Experiments and other types of hands-on activities are very important to student learning in the science classroom. Experiments can raise test scores and help a student become more engaged and interested in the material they are learning, especially when used over time. Experiments can vary from personal and informal natural comparisons (e. ...
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Radiation Therapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. Ionizing radiation works by damaging the DNA of cancerous tissue ...
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Nicotinamide
Niacinamide or Nicotinamide (NAM) is a form of vitamin B3 found in food and used as a dietary supplement and medication. As a supplement, it is used by mouth to prevent and treat pellagra (niacin deficiency). While nicotinic acid (niacin) may be used for this purpose, niacinamide has the benefit of not causing skin flushing. As a cream, it is used to treat acne. It is a water-soluble vitamin. Niacinamide is the supplement name while Nicotinamide (NAM) is the scientific name. Side effects are minimal. At high doses liver problems may occur. Normal amounts are safe for use during pregnancy. Niacinamide is in the vitamin B family of medications, specifically the vitamin B3 complex. It is an amide of nicotinic acid. Foods that contain niacinamide include yeast, meat, milk, and green vegetables. Niacinamide was discovered between 1935 and 1937. It is on the World Health Organization's List of Essential Medicines. Niacinamide is available as a generic medication and over the c ...
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Artificial Cerebrospinal Fluid
Artificial cerebrospinal fluid (aCSF) is a buffer solution prepared with a composition representative of cerebrospinal fluid that is used experimentally to immerse isolated brains, brain slices, or exposed brain regions to supply oxygen, maintain osmolarity, and to buffer pH at biological levels. ACSF is commonly used for electrophysiology experiments to maintain the neurons that are being studied. Composition One protocol for electrophysiology recording suggests the following composition for aCSF, with the pH and oxygen level stabilized by bubbling with carbogen Carbogen, also called Meduna's Mixture after its inventor Ladislas J. Meduna, Ladislas Meduna, is a mixture of carbon dioxide and oxygen gas. Meduna's original formula was 30% CO2 and 70% oxygen, but the term carbogen can refer to any mixture of t ... (95% O and 5% CO): * 127 mM NaCl * 1.0 mM KCl * 1.2 mM KH2PO4 * 26 mM NaHCO3 * 10 mM D-glucose * 2.4 mM CaCl2 * 1.3 mM MgCl2 References {{Neuroscience-stub Neuroph ...
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Central Retinal Artery Occlusion
Central retinal artery occlusion (CRAO) is a disease of the eye where the flow of blood through the central retinal artery is blocked (occluded). There are several different causes of this occlusion; the most common is carotid artery atherosclerosis. Signs and symptoms Central retinal artery occlusion is characterized by painless, acute vision loss in one eye. Upon fundoscopic exam, one would expect to find: cherry-red spot (90%) (a morphologic description in which the normally red background of the choroid is sharply outlined by the swollen opaque retina in the central retina), retinal opacity in the posterior pole (58%), pallor (39%), retinal arterial attenuation (32%), and optic disk edema (22%). During later stages of onset, one may also find plaques, emboli, and optic atrophy. Diagnosis One diagnostic method for the confirmation of CRAO is Fluorescein angiography, it is used to examine the retinal artery filling time after the fluorescein dye is injected into t ...
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State University Of New York Press
The State University of New York (SUNY, , ) is a system of public colleges and universities in the State of New York. It is one of the largest comprehensive system of universities, colleges, and community colleges in the United States. Led by chancellor John B. King, the SUNY system has 91,182 employees, including 32,496 faculty members, and some 7,660 degree and certificate programs overall and a $13.08 billion budget. Its flagship universities are Stony Brook University and the University at Buffalo. SUNY's administrative offices are in Albany, the state's capital, with satellite offices in Manhattan and Washington, D.C. With 25,000 acres of land, SUNY's largest campus is SUNY College of Environmental Science and Forestry, which neighbors the State University of New York Upstate Medical University - the largest employer in the SUNY system with over 10,959 employees. The State University of New York was established in 1948 by Governor Thomas E. Dewey, through legislative i ...
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Abreaction
Abreaction (german: Abreagieren) is a psychoanalytical term for reliving an experience to purge it of its emotional excesses—a type of catharsis. Sometimes it is a method of becoming conscious of repressed traumatic events. Psychoanalytic origins The concept of abreaction may have actually been initially formulated by Freud's mentor, Josef Breuer; but it was in their joint work of 1895, '' Studies on Hysteria'', that it was first made public to denote the fact that pent-up emotions associated with a trauma can be discharged by talking about it. The release of strangulated affect by bringing a particular moment or problem into conscious focus, and thereby abreacting the stifled emotion attached to it, formed the cornerstone of Freud's early cathartic method of treating hysterical conversion symptoms. For instance, they believed that pent-up emotions associated with trauma can be discharged by talking about it. Freud and Breur, however, did not treat the spontaneous emotional reli ...
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Psychotherapeutic
Psychotherapy (also psychological therapy, talk therapy, or talking therapy) is the use of psychological methods, particularly when based on regular personal interaction, to help a person change behavior, increase happiness, and overcome problems. Psychotherapy aims to improve an individual's well-being and mental health, to resolve or mitigate troublesome behaviors, beliefs, compulsions, thoughts, or emotions, and to improve relationships and social skills. Numerous types of psychotherapy have been designed either for individual adults, families, or children and adolescents. Certain types of psychotherapy are considered evidence-based for treating some diagnosed mental disorders; other types have been criticized as pseudoscience. There are hundreds of psychotherapy techniques, some being minor variations; others are based on very different conceptions of psychology. Most involve one-to-one sessions, between the client and therapist, but some are conducted with groups, inclu ...
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